Supplementary Information (doc 290K)
... dynamics are highly conserved in both species; however its induction at 2 hours did not meet the predefined significance level (see supplementary methods). Figure 7: Robustness of the early-response network assessed by edge permutations. In each permutation step, one edge of the network is deleted, ...
... dynamics are highly conserved in both species; however its induction at 2 hours did not meet the predefined significance level (see supplementary methods). Figure 7: Robustness of the early-response network assessed by edge permutations. In each permutation step, one edge of the network is deleted, ...
Beyond Dominant and Recessive Alleles
... • Many traits are produced by the interaction of several genes. • Traits controlled by two or more genes are said to be polygenic traits. • Skin color in humans is caused by multiple genes that code for melanin in the skin. • Many genetic disorders are polygenic such as autism, diabetes, and cancer. ...
... • Many traits are produced by the interaction of several genes. • Traits controlled by two or more genes are said to be polygenic traits. • Skin color in humans is caused by multiple genes that code for melanin in the skin. • Many genetic disorders are polygenic such as autism, diabetes, and cancer. ...
Supplementary Figure and Table Legend (doc 44K)
... competitive microarray comparing CD44+/CD24- fraction versus ‘rest’ fraction of NBLE cells. (b) Validation of competitive microarray comparing CD44+/CD24- fraction versus ‘rest’ fraction of CB272 cells. (The inset tables show fold changes observed in the respective microarray data). Supplementary Fi ...
... competitive microarray comparing CD44+/CD24- fraction versus ‘rest’ fraction of NBLE cells. (b) Validation of competitive microarray comparing CD44+/CD24- fraction versus ‘rest’ fraction of CB272 cells. (The inset tables show fold changes observed in the respective microarray data). Supplementary Fi ...
bioinformatix-ex
... first calculate the fold changes for each gene between every two time points in the time series as (ln t2 – ln t1). b) Based on the newly calculated fold change table we apply a t-Test between the two different populations, based on which we can calculate the significance (p-value) of the changes be ...
... first calculate the fold changes for each gene between every two time points in the time series as (ln t2 – ln t1). b) Based on the newly calculated fold change table we apply a t-Test between the two different populations, based on which we can calculate the significance (p-value) of the changes be ...
Chapter 11 Genetic and Meiosis
... This fact means that alleles are capable of segregate independently Independent Assortment – genes for different traits are able to separate on their own and do not influence each others inheritance ...
... This fact means that alleles are capable of segregate independently Independent Assortment – genes for different traits are able to separate on their own and do not influence each others inheritance ...
Mendel & Heredity
... Probability – the likelihood that a specific event will occur Pedigree – Identifying patterens of inheritance within a family over several ...
... Probability – the likelihood that a specific event will occur Pedigree – Identifying patterens of inheritance within a family over several ...
cognitive measures (set-shifting)
... Magnus Institute of Neuroscience, Dept. of Neuroscience and Pharmacology, University Medical Center Utrecht, The Netherlands Centre for Eating Disorders, Altrecht Mental Health Institute, Zeist, The Netherlands 3-Dept. of Clinical & Health Psychology, Utrecht University, The Netherlands 4-Rudolf Mag ...
... Magnus Institute of Neuroscience, Dept. of Neuroscience and Pharmacology, University Medical Center Utrecht, The Netherlands Centre for Eating Disorders, Altrecht Mental Health Institute, Zeist, The Netherlands 3-Dept. of Clinical & Health Psychology, Utrecht University, The Netherlands 4-Rudolf Mag ...
The Two Versions of the Human Genome - Max-Planck
... down on paper. Why is it important to know how certain mutations are distributed between the two parts of the genome? “Because, it can mean, for instance, the difference between cancer and no cancer,” she says. “If there are two mutations – for example, of the BRCA1 risk gene associated with breast ...
... down on paper. Why is it important to know how certain mutations are distributed between the two parts of the genome? “Because, it can mean, for instance, the difference between cancer and no cancer,” she says. “If there are two mutations – for example, of the BRCA1 risk gene associated with breast ...
Document
... b. Alkaptonuria is much more common in 1st cousin marriages than marriages with unrelated partners. ...
... b. Alkaptonuria is much more common in 1st cousin marriages than marriages with unrelated partners. ...
Gene Network Central
... • To see which genes are expressed in a tissue of interest, use the “View Tissue-Specific Association” drop-down menu to view known associations for the tissue of interest. • The image to the right shows associations that have been reported from normal human blood samples. ...
... • To see which genes are expressed in a tissue of interest, use the “View Tissue-Specific Association” drop-down menu to view known associations for the tissue of interest. • The image to the right shows associations that have been reported from normal human blood samples. ...
Yeast, Flies, Worms, and Fish
... ganism known to have a specific mutation in a gene PEN-2.41 Further study of these proteins may yield of interest. The added mutations in other genes may insights into the function of presenilins and may modify the usual phenotype, thereby providing clues thus suggest new therapeutic targets. to the ...
... ganism known to have a specific mutation in a gene PEN-2.41 Further study of these proteins may yield of interest. The added mutations in other genes may insights into the function of presenilins and may modify the usual phenotype, thereby providing clues thus suggest new therapeutic targets. to the ...
local FDR - Stanford Translational Medicine
... • Pi is the p value of the ordered gene i, Ri is the total number of rejected genes whose p-values are less than the threshold t=Pi and m̂0 Is an estimate of the total number of non-differentially expressed genes, m0 • the q-value tries to attach each feature with a significance measure • the q-valu ...
... • Pi is the p value of the ordered gene i, Ri is the total number of rejected genes whose p-values are less than the threshold t=Pi and m̂0 Is an estimate of the total number of non-differentially expressed genes, m0 • the q-value tries to attach each feature with a significance measure • the q-valu ...
Subtle Accents
... Hybrids – the offspring of crosses between parents with different traits Genes – a sequence of DNA that determines a particular trait ...
... Hybrids – the offspring of crosses between parents with different traits Genes – a sequence of DNA that determines a particular trait ...
embj201284303-sup-0001-SupportingInformation
... Supplementary Methods and Materials Supplementary Figures and Legends (Please see Supplementary Tables S1, S2, and S4 in separate Excel sheets) Supplementary Table S3 Supplementary Table S5 Supplementary References ...
... Supplementary Methods and Materials Supplementary Figures and Legends (Please see Supplementary Tables S1, S2, and S4 in separate Excel sheets) Supplementary Table S3 Supplementary Table S5 Supplementary References ...
a π i, π i+1
... • GENSCAN uses a training set in order to estimate the HMM parameters, then the algorithm returns the exon structure using maximum likelihood approach standard to many HMM algorithms (Viterbi algorithm). • Biological input: Codon bias in coding regions, gene structure (start and stop codons, typical ...
... • GENSCAN uses a training set in order to estimate the HMM parameters, then the algorithm returns the exon structure using maximum likelihood approach standard to many HMM algorithms (Viterbi algorithm). • Biological input: Codon bias in coding regions, gene structure (start and stop codons, typical ...
Exam 3 Multiple Choice Practice Questions
... 1. Which of the following describes an organism’s relative fitness? a) survival b) number of matings c) adaptation to the environment d) successful competition of resources e) relative number of visible offspring 2. According to the Hardy-Weinberg principle, a) the allele frequencies of a population ...
... 1. Which of the following describes an organism’s relative fitness? a) survival b) number of matings c) adaptation to the environment d) successful competition of resources e) relative number of visible offspring 2. According to the Hardy-Weinberg principle, a) the allele frequencies of a population ...
Kartagener`s Syndrome: a relentless triad
... – Looking for markers linked with the disease in affected families ...
... – Looking for markers linked with the disease in affected families ...
Reconciling the many faces of lateral gene transfer
... one or more ORFs, and whose length is rounded to the nearest ~500 bp; different colours represent segments of transferred DNA identified by either or both methods. Despite several reasons why these procedures are expected to identify somewhat different sets of genes, the degree of overlap (red bars) ...
... one or more ORFs, and whose length is rounded to the nearest ~500 bp; different colours represent segments of transferred DNA identified by either or both methods. Despite several reasons why these procedures are expected to identify somewhat different sets of genes, the degree of overlap (red bars) ...
Identification and functional analysis of novel genes
... demonstrated to substitute for each other thus ensuring the robustness of development. To determine the functional redundancy among similar proteins in the embryonic germline of Drosophila, we performed a largescale combinatorial gene silencing experiment. We co-silenced the gene-pairs that are para ...
... demonstrated to substitute for each other thus ensuring the robustness of development. To determine the functional redundancy among similar proteins in the embryonic germline of Drosophila, we performed a largescale combinatorial gene silencing experiment. We co-silenced the gene-pairs that are para ...
Genetics (patterns of inheritance) - Jocha
... Example: HEMOPHILIA is a X-linked trait in humans. Let N=normal allele and n=hemophilia allele If a woman who is heterozygous (carrier) for the trait has children with a man who is normal Genotype woman=XN Xn and male=XN Y As meiosis separates alleles for the trait, only one allele can be present fo ...
... Example: HEMOPHILIA is a X-linked trait in humans. Let N=normal allele and n=hemophilia allele If a woman who is heterozygous (carrier) for the trait has children with a man who is normal Genotype woman=XN Xn and male=XN Y As meiosis separates alleles for the trait, only one allele can be present fo ...
CHAPTER OUTLINE
... CHAPTER OUTLINE 24.1 Gene Linkage All the alleles on one chromosome form a linkage group because they tend to be inherited together and do not show independent assortment. 24.2 Sex-Linked Inheritance Out of 23 pairs of chromosomes, 22 are called autosomes and one pair is the sex chromosomes, so name ...
... CHAPTER OUTLINE 24.1 Gene Linkage All the alleles on one chromosome form a linkage group because they tend to be inherited together and do not show independent assortment. 24.2 Sex-Linked Inheritance Out of 23 pairs of chromosomes, 22 are called autosomes and one pair is the sex chromosomes, so name ...
REGULATION OF GENE EXPRESSION
... DNA methylation prevents the binding of the transcriptional machinery and is associated with transcriptional silencing. DNA methylation.is the underlying mechanism of a genetic process called imprinting which is considered as an epigenetic inheritance. In a diploid cell, a gene exists in two copies ...
... DNA methylation prevents the binding of the transcriptional machinery and is associated with transcriptional silencing. DNA methylation.is the underlying mechanism of a genetic process called imprinting which is considered as an epigenetic inheritance. In a diploid cell, a gene exists in two copies ...
Hereditary risks associated with preeclampsia
... best goodness of fit for • a major dominant gene with about 30% penetrance – (homozygous 1% and heterozygous 10-12%) ...
... best goodness of fit for • a major dominant gene with about 30% penetrance – (homozygous 1% and heterozygous 10-12%) ...
Crossing Over - Biology D118
... has genes 3 (E) and gene 4 (F). They are now four different chromosomes, and when these chromosomes are distributed to sperm or egg cells, four different cells can result. Without crossing over only two different cells could result. 9. Crossing over is tremendously significant in the evolutionary pr ...
... has genes 3 (E) and gene 4 (F). They are now four different chromosomes, and when these chromosomes are distributed to sperm or egg cells, four different cells can result. Without crossing over only two different cells could result. 9. Crossing over is tremendously significant in the evolutionary pr ...