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... B,G = standard Beta & Gamma functions N = number of aligned sites; T = number of total possible sites Fjb = number of occurrences of base b at position j (F = sum) Gb = background genomic frequency for base b bb = n x Gb for n pseudocounts (b = sum) W = width of motif; C = number of columns in motif ...
Signals of recent positive selection in a worldwide sample of human
Signals of recent positive selection in a worldwide sample of human

... pairwise FST between geographic regions in a 100-kb window surrounding the SNP in the HGDP data, as well as a histogram of the null distribution calculated by finding the maximum FST in 100-kb windows surrounding each of 10,000 random SNPs. The dotted lines shows the position beyond which 5% of the ...
chapter_16
chapter_16

... Even-numbered polyploids are more likely to be fertile because of potential for equal segregation during meiosis. Odd-numbered polyploids have unpaired chromosomes and usually are sterile. Most seedless fruits are triploid. ...
Quantitative Genetics and Whole Genome Approaches
Quantitative Genetics and Whole Genome Approaches

... B. Backcross the F1 to the parental strains C. Examine the F2 phenotype and the genetic markers D. Cosegregation between the trait and a marker or markers suggests the QTL is nearby E. Examples using various methods 1. Backcrossing F1 to the parental strains and examining F2 directly a. DDT resistan ...
Male Female vg + b + pr + vg b + pr + vg + b pr + vg b pr + vg + b + pr
Male Female vg + b + pr + vg b + pr + vg + b pr + vg b pr + vg + b + pr

... 1. 100’s of DNA markers mapped onto each chromosome – high density linkage map. the relative location of 100s of polymorphic DNA markers on chromosomes can be mapped using mapping panels. 2. identify markers linked to trait of interest by recombination analysis. Use LOD score to determine if markers ...
Supplementary Results dN/dS Complete results for all three models
Supplementary Results dN/dS Complete results for all three models

... In the branch-site evolutionary model, we see six mce genes showing significant positive selection on the branch leading to the pathogenic Mycobacteria: mce1D, mce1C, mce4F, mce1A, mce4E, and mce4D. Genes involved in the synthesis of mycolic acid coat. The PFAM group for cyclopropanefatty-acyl-phosp ...
18.1 The Basis of Heredity Genetics: is the study of heredity Heredity
18.1 The Basis of Heredity Genetics: is the study of heredity Heredity

... Half coloured means the person is heterozygous for an autosomal recessive In each pedigree diagram:  Generations are numbered using roman numerals  Individuals within each generation are numbered using Arabic numbers  Males are represented by squares  Females are represented by circles ...
High frequency of TTTY2-like gene-related deletions in patients with
High frequency of TTTY2-like gene-related deletions in patients with

... spermatogenesis and they imply that additional genetic tests of Y chromosome deletions is necessary in couples with fertility problems", says Prof. Yapijakis. The studied cohort of 94 infertile patients was divided into three groups as following: group A (n = 28) included men with idiopathic moderat ...
No Slide Title
No Slide Title

... Human Oddities • 3 promoters: 2 on H strand, one on L • pL transcribes entire light strand; later processed into tRNA & ND6 • pH1 transcribes entire H strand • pH2 may transcribe 12S & 16S rRNA • In vitro only need TFAM & TFB2M to transcribe pL & pH1 • Uncertain if pH2 is used ...
Genetics Terms You`ve Gotta Know
Genetics Terms You`ve Gotta Know

... Homozygous: When a person’s two alleles for a gene are the same (AA or aa)  Heterozygous: When a person’s two alleles for a gene are different (Aa)  You get one allele from your mom and one from your dad.  If you get the same alleles from your mom and dad, you are homozygous for that trait.  If ...
chapter 19 the organization and control of eukaryotic
chapter 19 the organization and control of eukaryotic

...  Gene expression must be controlled on a long-term basis during cellular differentiation, the divergence in form and function as cells in a multicellular organism specialize.  A typical human cell probably expresses about 20% of its genes at any given time.  Highly specialized cells, such as nerv ...
Chart 1
Chart 1

... ** With the multifactorial inheritance  most congenital malformations and many common adult diseases are the result of a complex interaction of multiple genetic and environmental factors. - Multiple genes as well as multiple environmental factors influence them CHROMOSOMAL DELETION SYNDROMES ...
Section 1: Mutation and Genetic Change Preview • Bellringer • Key
Section 1: Mutation and Genetic Change Preview • Bellringer • Key

... DNA and chromosomes are involved in many processes, so there are many kinds of mutations. Most mutations involve a misplacement of a nucleotide in a DNA segment. A mutation may change the results of a gene (when the gene is translated and transcribed), but not all mutations do so. Different kinds of ...
Biology 2
Biology 2

... replication. Then replication proceeds in both directions, creating replicating bubbles. The parental DNA strands open up as the daughter strands elongate on both sides of each bubble. Thousands of bubbles can be present at once. Eventually, all the bubbles merge, yielding two completed daughter DNA ...
Segregation, Assortment, and Dominance Relationships
Segregation, Assortment, and Dominance Relationships

... information for the correct amino acid sequence; Therefore, its protein product in nonfunctional In the heterozygote, the dominant allele encodes sufficient production of the protein to produce the dominant phenotype. This is also called complete dominance ...
Ch - TeacherWeb
Ch - TeacherWeb

... Main Idea: The crossing over of linked genes is a source of genetic variation. a. ...
mendelian genetics powerpoint 2013
mendelian genetics powerpoint 2013

... only have sons, no daughters. I don't want to have any daughters who might be color blind and have so many problems like I do. Color blindness wouldn't matter so much for a boy. ...
L12 Intro to Inheritance Fa08
L12 Intro to Inheritance Fa08

... • Mendel worked with characteristics that were controlled by simple dominant/recessive inheritance of one gene • Many diseases controlled by a single gene • Most genetic disorders recessive – Most from 2 heterozygous parents – The closer the parents are related, the more likely they are to carry the ...
Multiple Comparisons with Gene Expression Arrays Using a Data
Multiple Comparisons with Gene Expression Arrays Using a Data

... • tissue samples of nodules and surrounding • analysed with Affymetrix® Gene Chips • Signal log ratio nodule vs. surrounding from each patient for each of 12.625 genes • outlier catching by additional logistic transformation ...
Dominant Recessive
Dominant Recessive

... – Most pea plants self pollinate (true breeding) – Mendel forced plants to cross pollinate (have 2 plants) ...
Genetics Listening Bingo
Genetics Listening Bingo

... with many pea plants with many different traits • For each, he discovered that there seem to be “factors” that disappeared in one generation and then reappeared in the next • This went against the idea that an organism is a blend of their parents’ traits ...
Section 11_3 notes - Vista del Lago High School
Section 11_3 notes - Vista del Lago High School

... • During meiosis, genes for ...
Biology 3201 Chromosomal Mutations Information Table
Biology 3201 Chromosomal Mutations Information Table

... chromosomes (46) in every cell. Other symptoms include: short with female genitalia but no ovaries or menstrual period, webbed neck, heart defects, kidney and skeletal abnormalities, learning difficulty, and thyroid disfunction. Treatments include: Injections of HGH to improve height and injections ...
cDNA Sequences of Three Kinds of /3
cDNA Sequences of Three Kinds of /3

... 3.1. Structure and features of rice 0-tubulins Figure 1 shows the structure of three completely sequenced /3-tubulin cDNA clones. Similarity in the nucleotide sequence among the three clones was high in their open reading frames. For example, similarities between pTUB22 and R2242, pTUB22 and R1623. ...
Unit 8.2: Human Inheritance
Unit 8.2: Human Inheritance

... form bones. The gene for this protein also affects the ears and eyes. This was discovered from mutations in the gene. They result in problems not only in bones but also in these sensory organs. ...
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Genomic imprinting

Genomic imprinting is the epigenetic phenomenon by which certain genes are expressed in a parent-of-origin-specific manner. If the allele inherited from the father is imprinted, it is thereby silenced, and only the allele from the mother is expressed. If the allele from the mother is imprinted, then only the allele from the father is expressed. Forms of genomic imprinting have been demonstrated in fungi, plants and animals. Genomic imprinting is a fairly rare phenomenon in mammals; most genes are not imprinted.In insects, imprinting affects entire chromosomes. In some insects the entire paternal genome is silenced in male offspring, and thus is involved in sex determination. The imprinting produces effects similar to the mechanisms in other insects that eliminate paternally inherited chromosomes in male offspring, including arrhenotoky.Genomic imprinting is an inheritance process independent of the classical Mendelian inheritance. It is an epigenetic process that involves DNA methylation and histone methylation without altering the genetic sequence. These epigenetic marks are established (""imprinted"") in the germline (sperm or egg cells) of the parents and are maintained through mitotic cell divisions in the somatic cells of an organism.Appropriate imprinting of certain genes is important for normal development. Human diseases involving genomic imprinting include Angelman syndrome and Prader–Willi syndrome.
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