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Interactive Visualization of Gene Regulatory Networks with
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... for visualization of gene regulatory networks. Gene regulatory networks can be represented by graphs, in which nodes represent genes, and edges represent interactions between a gene product (a regulator protein) and its target genes. The nodes have several attributes, such as position on the chromos ...
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... • genes carried on X chromosome are absent from the Y chromosome • a recessive sex-linked allele is expressed in the phenotype of a male – females may be “carriers” – males express the single allele ...
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... PART A: BASIC GENETICS 1. Widow’s peak is dominant to no widow’s peak. Determine the genotype and phenotype ratios for a cross between a homozygous dominant female and a homozygous recessive male. 2. Dimples is dominant to no dimples. Determine the genotype and phenotype ratios for a cross between a ...
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... • Both the mother and the father of a colorblind male appear to be normal. From whom did the son inherit the allele for colorblindness? What are the genotypes of the mother, father, and the son? • A woman is colorblind. What are the chances that her son will be colorblind? If she is married to a man ...
computational biology
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... REFERENCE. SEGMENT is a new keyword here. The FEATURES table is what really makes a eukaryotic genomic entry special, and as such, is much longer than the ones for prokaryotic organisms. It contains the following elements: • The source section contains a /map section. For AF018430, it indicates thet ...
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... found to be associated with large domains up to several megabases in length, which cover about 40% of the genome in mouse and human cells [6,7]. In flies, however, the size and the coverage of lamin-associated regions were not determined precisely because the cDNA microarrays used for detection cont ...
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... morphogenetic mechanisms listed above occur during Drosophila gastrulation, although the initial and most dramatic events are mediated only by shape changes of epithelia and by cell intercalation within epithelia. Our own work, and this review, concentrates on an example of epithelial invagination, ...
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... word “different” itself is a fuzzy concept and fuzzy theory has many advantages in dealing with data containing uncertainty; therefore fuzzy approaches have been taken into consideration to analyze DNA microarrays. Liang et al. [1] proposed a fuzzy set theory based approach, namely a fuzzy membershi ...
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... Automatically finds genes and other features of the sequence Associates sequence and features with data from other sources Provides a publicly accessible web based interface to the database ...
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... and many genes encoding hypothetical proteins that have not previously been established as essential. Three genes selected from our list of genes predicted to be essential, pyrH, accA, and sodB, were independently confirmed to be essential through the generation of conditional mutants, validating ou ...
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... methylcytosine-binding protein MeCP2 (Nan et al., 1997 ). ...
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Genomic imprinting

Genomic imprinting is the epigenetic phenomenon by which certain genes are expressed in a parent-of-origin-specific manner. If the allele inherited from the father is imprinted, it is thereby silenced, and only the allele from the mother is expressed. If the allele from the mother is imprinted, then only the allele from the father is expressed. Forms of genomic imprinting have been demonstrated in fungi, plants and animals. Genomic imprinting is a fairly rare phenomenon in mammals; most genes are not imprinted.In insects, imprinting affects entire chromosomes. In some insects the entire paternal genome is silenced in male offspring, and thus is involved in sex determination. The imprinting produces effects similar to the mechanisms in other insects that eliminate paternally inherited chromosomes in male offspring, including arrhenotoky.Genomic imprinting is an inheritance process independent of the classical Mendelian inheritance. It is an epigenetic process that involves DNA methylation and histone methylation without altering the genetic sequence. These epigenetic marks are established (""imprinted"") in the germline (sperm or egg cells) of the parents and are maintained through mitotic cell divisions in the somatic cells of an organism.Appropriate imprinting of certain genes is important for normal development. Human diseases involving genomic imprinting include Angelman syndrome and Prader–Willi syndrome.
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