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p53
p53

... translated repeatedly in these cells. ...
ppt - Chair of Computational Biology
ppt - Chair of Computational Biology

... An HMM is a graph of connected states, each state potentially able to “emit” a series of observations. The process evolves in some dimension, often time, though not necessarily. The model is parameterized with probabilities governing the state at a time t + 1, given that one knows the previous state ...
Comparison between Human and Mouse genomes
Comparison between Human and Mouse genomes

... Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD. Automated partial DNA sequencing was conducted on more than 600 randomly selected human brain complementary DNA (cDNA) clones to generate expressed sequence tags (ESTs). ESTs have applications in the discovery of new hum ...
CHAPTER 14 MENDEL AND THE GENE IDEA
CHAPTER 14 MENDEL AND THE GENE IDEA

...  They had purple flowers because the allele for that trait is dominant. 4. 4. Mendel’s law of segregation states that the two alleles for a heritable character separate and segregate during gamete production and end up in different gametes.  This segregation of alleles corresponds to the distribut ...
Genome-scale CRISPR pooled screens
Genome-scale CRISPR pooled screens

... sgRNAs, and then counting the frequency of each sgRNA after nextgeneration sequencing (Fig. 1B). Ideally, the initial distribution of the library is as uniform as possible so that, after selection, any depletion or enrichment of specific sgRNAs is readily identifiable. In reality, biases can be introd ...
P generation
P generation

... that two or more independent events will occur together is the product of their individual probabilities  This can be applied to an F1 monohybrid cross  Segregation in a heterozygous plant is like flipping a coin: Each gamete has a 12 chance of carrying the dominant allele and a 12 chance of carry ...
Franks et al 2016 Mol Ecol - Department of Ecology and Evolution
Franks et al 2016 Mol Ecol - Department of Ecology and Evolution

... These ancestor-descendant comparisons revealed evolutionary shifts in allele frequencies in many genes. Some genes showing evolutionary shifts have functions related to drought stress and flowering time, consistent with an adaptive response to selection. Loci differentiated between ancestors and des ...
GENETIC CALCULATOR (HORSE COLOUR) Help File
GENETIC CALCULATOR (HORSE COLOUR) Help File

... single factor and double factor Tobiano horses cannot reliably be determined by visual inspection. The size of the white patches varies considerably from completely white body to completely normal body (the latter being the likely source of “Crop out” individuals). As the Chestnut, Roan and Tobiano ...
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Who was Gregor Mendel

... Theory (not really Mendel’s) Hereditary information is transmitted from parents to offspring as ___________ found on chromosomes. These genes determine an individual’s traits. ...
Statistical analysis of DNA microarray data
Statistical analysis of DNA microarray data

Presentation
Presentation

... This is when one allele of a pair isn’t fully dominant over its partner, so a heterozygous phenotype somewhere in between the two homozygous phenotypes emerges (creating a ...
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list of publications

... In multicellular organisms, the division of a single totipotent cell, the homologues are highly conserved, and a substantial number of papers describe fertilized zygote, ultimately results in a myriad of cells with different structures their mode of action, it remains unknown how any of these protei ...
Document
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... of a run-off transcription assay using a DNA fragment with two spoVG promoters spaced 10 bp apart, The fraction numbers at the top of the inset correspond to the fraction numbers from the column at bottom. The last lane (M) contained marker DNA fragments. The two arrowheads at the left of the inset ...
Four Genes Affecting Seed Traits in Soybeans Map to Linkage
Four Genes Affecting Seed Traits in Soybeans Map to Linkage

... which are encoded by Gy4 ( Kitamura et al. 1984; Staswick and Nielsen 1983). The absence of these protein subunits can be used for mapping the Cgy1 and Gy4 genes. T311 is a shriveled seed mutant. This trait is inherited as a single recessive allele, with partial penetrance and incomplete expressivit ...
Bioinfo_primer_01
Bioinfo_primer_01

Gene Expression in C. elegans - Buffalo State College Faculty and
Gene Expression in C. elegans - Buffalo State College Faculty and

... cells, 959 somatic cells, and the lineage of each cell in the adult worm is known ...
Detailed Supporting Information
Detailed Supporting Information

... the pellet in 2 mL ice-cold 12% PCA in the old 50 mL tube we placed the tubes in an ultrasound ice bath for 5 min. We collected the supernatants, and lyophilized them in a freeze-dry system overnight. After re-suspending 13C, 1H and 31P spectra were obtained on a 9T Brucker vertical bore instrument ...
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Author`s personal copy

... reducers, including denitrifiers from environmental samples, by using nutrient rich media and anaerobic conditions with nitrogen oxides as electron acceptors [73]. Although a variety of denitrifying bacteria were isolated successfully from soil [19,21,29] these cultivation attempts generally resulted ...
miRNA pptx - NUS School of Computing
miRNA pptx - NUS School of Computing

Quantitative analysis of NOR expression in a B chromosome of the
Quantitative analysis of NOR expression in a B chromosome of the

... The mechanisms regulating the activation of ribosomal chromatin are less understood than those responsible for repression (Huang et al. 2006). Chromosome context appears to be important for NOR activity, as deduced from changes in the on/off activity status following chromosome rearrangements moving ...
Microarray Data Analysis
Microarray Data Analysis

... Expression ratio of control gene or house keeping should not be change under two conditions, but often one finds that it deviates from 1. This may be due to various reasons, for example, variation caused by differential labeling efficiency of the two fluorescent dyes, or different amounts of startin ...
Gene - Representing Genes
Gene - Representing Genes

... any heritable change in the nucleotide sequence of a chromosome, which may occur either by the substitution of one nucleotide for another or by the translocation or inversion of a chromosome segment. In classical genetics, however, mutation was necessarily defined as a change in the intrinsic nature ...
2015 JUNIOR GENETICS EASY 4455 (easy) HIH1040-1/ES94
2015 JUNIOR GENETICS EASY 4455 (easy) HIH1040-1/ES94

... Q: What is the dense center of a cell that contains the genetic material? A: Nucleus 4461 (easy) TH447/HIH1060-1 Q: 2 part question: How many pairs of chromosomes are there in a horse & are these pairs always identical in nature? A: 32 pairs; not always identical 4462 (easy) HIH1060-1/HS19/TH458-9/E ...
PPT
PPT

... REDUCE algorithm has high runtime ...
Pearl millet, food for the future in the Sahel
Pearl millet, food for the future in the Sahel

... and also certain morphological traits such as spike length and stem diameter. Flowering time was strongly linked to climatic conditions: a long flowering time was better adapted to more humid climates, a shorter one suitable for drier conditions. For example, the species cultivated in coastal tropic ...
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Genomic imprinting

Genomic imprinting is the epigenetic phenomenon by which certain genes are expressed in a parent-of-origin-specific manner. If the allele inherited from the father is imprinted, it is thereby silenced, and only the allele from the mother is expressed. If the allele from the mother is imprinted, then only the allele from the father is expressed. Forms of genomic imprinting have been demonstrated in fungi, plants and animals. Genomic imprinting is a fairly rare phenomenon in mammals; most genes are not imprinted.In insects, imprinting affects entire chromosomes. In some insects the entire paternal genome is silenced in male offspring, and thus is involved in sex determination. The imprinting produces effects similar to the mechanisms in other insects that eliminate paternally inherited chromosomes in male offspring, including arrhenotoky.Genomic imprinting is an inheritance process independent of the classical Mendelian inheritance. It is an epigenetic process that involves DNA methylation and histone methylation without altering the genetic sequence. These epigenetic marks are established (""imprinted"") in the germline (sperm or egg cells) of the parents and are maintained through mitotic cell divisions in the somatic cells of an organism.Appropriate imprinting of certain genes is important for normal development. Human diseases involving genomic imprinting include Angelman syndrome and Prader–Willi syndrome.
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