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Analysis of Clines with Variable Selection and Variable Migration
Analysis of Clines with Variable Selection and Variable Migration

... and Barton 1989) to predict how much gene flow is required to fit the observed patterns. This method has some desirable properties of both direct methods, such as measuring dispersal over a specific timescale, and indirect methods, such as measuring the effective dispersal of genes and avoiding dire ...
here - Genomes Unzipped
here - Genomes Unzipped

... Li et al.[1] sequenced cDNA from lymphoblastoid cell lines derived from 27 individuals whose genomes have been sequenced at low coverage [2], and identified 10,210 sites of mismatches between an individual’s mRNA and DNA sequences (RDD sites, for RNA-DNA difference). RDD sites included all possible ...
Gene Section AIP (aryl hydrocarbon receptor interacting protein) in Oncology and Haematology
Gene Section AIP (aryl hydrocarbon receptor interacting protein) in Oncology and Haematology

... (aryl hydrocarbon receptor). AIP regulates its subcellular localization and degradation. AhR, also known as dioxin receptor is a ligand activated transcription factor found in the cytoplasm as part of a multiprotein complex with Hsp90 (Perdew, 1988), AIP (Carver and Bradfield, 1997; Meyer et al., 19 ...
Evolutionary significance of stress- induced mutagenesis in
Evolutionary significance of stress- induced mutagenesis in

... (MRS) (Figure I, 4a) [15] and induction of the dinB gene that codes for the error-prone translesion synthesis polymerase (Figure I, 4b) [45] result in increased mutagenesis [4,7,46], revealing the conflict between priorities during the stress response. (5) Stresses have also been shown to induce the ...
The Maintenance and Propagation of Plasmid Genes in Bacterial
The Maintenance and Propagation of Plasmid Genes in Bacterial

... Plasmids (like the chromosome) need to be efficiently partitioned to each daughter cell at cell division if they are to be stably inherited in a population. For a plasmid with a low copy number (e.g. 1-2 per chromosome), there must be active and efficient segregation if it is to be stably maintained ...
Quantitative analysis of SMN1 and SMN2 genes based on DHPLC
Quantitative analysis of SMN1 and SMN2 genes based on DHPLC

Genetic diversity and epidemiology of infectious hematopoietic
Genetic diversity and epidemiology of infectious hematopoietic

... obtained from only 1 site (hatchery,lake, etc.).The temporal pattern of the G F haplotypes suggested a 'genetic acclimation' of the G gene, possibly due to positive selection on the glycoprotein. A pairwise comparison of the sequence data determined that the maximum nucleotide d~versityof the isolat ...
Genetic and evolutionary analysis of diversification and reproductive
Genetic and evolutionary analysis of diversification and reproductive

... which genetic changes are responsible for the discontinuities between already established types (between two species of yeast, S. cerevisiae and S. paradoxus). In chapter three, I look at how nucleotide sequence variation can accumulate to such an extent that it prevents the segregation of diverged ...
Optimizing Testing Efficiency with Error
Optimizing Testing Efficiency with Error

... expectation to detect as many errors as possible with a test case) and the reliability of software. Testing coverage techniques have one major drawback which is they look at the entire program. Even with reduction methods there can be many test cases in a large program and it can become intractable ...
Fulltext PDF - Indian Academy of Sciences
Fulltext PDF - Indian Academy of Sciences

... on DNA sequence. The latter is in the form of cytosine methylation at CG, CHG and CHH elements (where H = A, T or C) and a variety of histone modifications in nucleosomes. The epialleles arising from cytosine methylation marks on the nuclear genomic loci have better heritability than the epiallelic v ...
Base Composition and Translational Selection are Insufficient to
Base Composition and Translational Selection are Insufficient to

... 5.7kb that is translated from subgenomic RNAs, and geminiviruses have one or two circular, ~2.7kb, ambisense genomic segments that are transcribed by host enzymes [23]. Unlike cellular organisms, which share related genes across extremely divergent clades, which can be used as the basis for phylogen ...
Aucsia Gene Silencing Causes Parthenocarpic Fruit Development in
Aucsia Gene Silencing Causes Parthenocarpic Fruit Development in

... Figure 1. Expression of SlAucsia-1 and SlAucsia-2 genes in tomato. A, cDNA-AFLP analysis showing down-regulation of SlAucsia-1 in preanthesis flower buds from two parthenocarpic auxin-synthesis (iaaM) tomato lines (DefH9-iaaM line 3 and DefH9-RI-iaaM line s5; Pandolfini et al., 2002). B, qRT-PCR ana ...
The molecular basis of human retinal and vitreoretinal
The molecular basis of human retinal and vitreoretinal

... basic research. Still, a reliable molecular diagnosis is possible for only half of the affected individuals or families with monogenic forms of retinal diseases. In addition, the predictive value of a mutation or risk allele for multifactorial disorders is problematic since the phenotypic and/or sym ...
Syntabulin, a motor protein linker, controls dorsal
Syntabulin, a motor protein linker, controls dorsal

... Quantitative (q) RT-PCR analysis was conducted to examine the expression of syntabulin, the other candidate genes and Wnt genes in wild-type and tkk embryos, using an ABI Prism 7000 (Applied Biosystems) or LightCycler 480 (Roche) with Power SYBR Green PCR Master Mix (Applied Biosystems) or SYBR Gree ...
Recommended Nomenclature for the Vertebrate Alcohol
Recommended Nomenclature for the Vertebrate Alcohol

... ADHs previously called ADHa, ADHb, and ADHg are named ADH1A, ADH1B, and ADH1C, respectively. For genes, we recommend the italicized root symbol “ADH” for human and “Adh” for mouse and rat, followed by the appropriate Arabic number for the class, and a letter if necessary for multiple isoenzymes with ...
Gene regulation in three dimensions
Gene regulation in three dimensions

... taking the time to answer my questions. Last, but not least I would like to thank Julie my fiancé who has supported me and been there for me when I needed it the most. K.T.W ...
::: Gene Set Enrichment Analysis - GSEA
::: Gene Set Enrichment Analysis - GSEA

... into a single gene vector, which is identified by its HUGO gene symbol. In this case, you are using HUGO gene symbols for the analysis. The gene sets that you use for the analysis must use HUGO gene symbols to identify the genes in the gene sets. 2. Choose false to use your expression dataset "as is ...
9th Grade Reading Problems of the Day
9th Grade Reading Problems of the Day

... fruit but not in its leaves. With the weed genes, the tomatoes turned dark green. The reason the tomatoes had been light green was that they had the uniform ripening mutation, which set up a sort of chain reaction. The mutation not only made tomatoes turn uniformly green and then red, but also disab ...
A-2015A: Amplified Fragment Length
A-2015A: Amplified Fragment Length

... times between instruments. In order to test these potential sources of variation, we compared a watercooled thermal cycler against a peltier cooled thermal cycler using the cycling program as described by Vos et al.[1] To this, we compared a substantially different program, as described in our previ ...
The CpG island methylator phenotype (CIMP) in
The CpG island methylator phenotype (CIMP) in

... interfering in responses to DNA damage. Sporadic MSI tumors are generally affected by promoter hypermethylation of the mismatch repair gene MLH1 resulting in the inactivation of this gene (6). The familial form of MSI CRC is hereditary non polyposis CRC (HNPCC, or Lynch syndrome), which is caused by ...
Prentice Hall Biology
Prentice Hall Biology

... Normal human body cells each contain 46 chromosomes. The cell division process that body cells undergo is called mitosis and produces daughter cells that are virtually identical to the parent cell. Working with a partner, discuss and answer the questions that follow. ...
IOSR Journal of Dental and Medical Sciences (IOSR-JDMS)
IOSR Journal of Dental and Medical Sciences (IOSR-JDMS)

... or more break points and exchange of genetic material between two or more chromosomes (1). Around 15 to 20% of pregnancies end up in spontaneous abortions (SABs) in humans. The incidence of chromosomal rearrangements in those abortions is as high as 50% and a majority of the rearrangements may be of ...
Inbreeding 1
Inbreeding 1

... Half of heterozygosity is lost each generation. ...
Recurrent Pregnancy Loss and Its Relation to Combined Parental
Recurrent Pregnancy Loss and Its Relation to Combined Parental

...  Just 2 % of pregnant women experience two consecutive pregnancy losses and only 0.4 to 1% have three consecutive pregnancy losses. ...
Review Article Viral Bacterial Artificial - diss.fu
Review Article Viral Bacterial Artificial - diss.fu

... Within a few days, genes or sequence elements can be removed. Foreign sequences can readily be inserted into the genome, allowing detection of viral proteins via epitope tags, or expression of foreign genes for development of vector vaccines [2–7]. Furthermore, reporter genes such as the green fluor ...
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Designer baby

Designer baby is a term that refers to the product of a genetically engineered baby. These babies are ""designed"" (fixed/changed) while still in the womb to achieve more desired looks, skills, or talents.
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