gemini Documentation
... As version 0.12.2 of GEMINI it is required that your input VCF file undergo additional preprocessing such that multiallelic variants are decomposed and normalized using the vt toolset from the Abecasis lab. Note that we have also decomposed and normalized all of the VCF-based annotation files (e.g., ...
... As version 0.12.2 of GEMINI it is required that your input VCF file undergo additional preprocessing such that multiallelic variants are decomposed and normalized using the vt toolset from the Abecasis lab. Note that we have also decomposed and normalized all of the VCF-based annotation files (e.g., ...
Duplication 12p and PallisterKillian syndrome
... FGFR2 as well as the GLI3 gene, all of which were within normal limits. BAC array comparative genomic hybridization was performed, and revealed a 12p13.31 microduplication and a 16p13.11 microdeletion. To further refine the breakpoint of microduplication, single nucleotide polymorphism (SNP) microarr ...
... FGFR2 as well as the GLI3 gene, all of which were within normal limits. BAC array comparative genomic hybridization was performed, and revealed a 12p13.31 microduplication and a 16p13.11 microdeletion. To further refine the breakpoint of microduplication, single nucleotide polymorphism (SNP) microarr ...
Optimal estimation of diffusion coefficients from single
... σ 2 , of localization errors, which receives also a contribution from true errors on localization due to photonic shot noise in images of the tracked object. However, substrate motion needs to be modeled to some degree beyond white noise if the longest time scale of substrate motion is comparable to ...
... σ 2 , of localization errors, which receives also a contribution from true errors on localization due to photonic shot noise in images of the tracked object. However, substrate motion needs to be modeled to some degree beyond white noise if the longest time scale of substrate motion is comparable to ...
hemipterous Encodes a Novel Drosophila MAP
... development. The cellular and mechanistic aspects of concerted cell movements have been described in several organisms, and a number of studies suggest an important role for cell communication in morphogenesis (for reviews, see Fristrom, ...
... development. The cellular and mechanistic aspects of concerted cell movements have been described in several organisms, and a number of studies suggest an important role for cell communication in morphogenesis (for reviews, see Fristrom, ...
Children and Their Development, Second Canadian Edition Kail
... 38) Why are relatively few inherited disorders caused by dominant alleles? A) Most disorders caused by dominant alleles lead to sterility, which means the dominant allele will not be passed on. B) Genetic testing can more readily identify dominant rather than recessive alleles; genetic counselling h ...
... 38) Why are relatively few inherited disorders caused by dominant alleles? A) Most disorders caused by dominant alleles lead to sterility, which means the dominant allele will not be passed on. B) Genetic testing can more readily identify dominant rather than recessive alleles; genetic counselling h ...
Computational Definition of
... sequence families comprising 2069 putative exonic enhancers and 974 putative exonic silencers. Representatives of each class indeed functioned as enhancers or silencers when inserted into a test exon and assayed in transfected mammalian cells. As a class, the enhancer sequencers were more prevalent ...
... sequence families comprising 2069 putative exonic enhancers and 974 putative exonic silencers. Representatives of each class indeed functioned as enhancers or silencers when inserted into a test exon and assayed in transfected mammalian cells. As a class, the enhancer sequencers were more prevalent ...
Selective Crossover Using Gene Dominance as an Adaptive
... evolutionary computing. It has been widely agreed that standard crossover in genetic programming is more bias towards local searching and not ideal to explore the search space of programs efficiently. It has been argued strongly, in both Genetic Algorithm (GA) and Genetic Programming (GP) that more ...
... evolutionary computing. It has been widely agreed that standard crossover in genetic programming is more bias towards local searching and not ideal to explore the search space of programs efficiently. It has been argued strongly, in both Genetic Algorithm (GA) and Genetic Programming (GP) that more ...
SPA1: A New Genetic Locus Involved in Phytochrome A
... rates of continuous far-red light that are absent in the parental phyA-105 mutant, such as deetiolation, anthocyanin accumulation, and a far-red light–induced inability of seedlings to green upon subsequent transfer to continuous white light. spa1 mutations do not cause a phenotype in darkness, indi ...
... rates of continuous far-red light that are absent in the parental phyA-105 mutant, such as deetiolation, anthocyanin accumulation, and a far-red light–induced inability of seedlings to green upon subsequent transfer to continuous white light. spa1 mutations do not cause a phenotype in darkness, indi ...
A Theory of Conceptual Advance: Explaining Conceptual Change in
... epistemological concern. The particular topic of the dissertation is conceptual change in science, more specifically, conceptual change in biology. The task of a discussion of conceptual change is the study of historical episodes in science so as to offer a philosophical account of how and why scien ...
... epistemological concern. The particular topic of the dissertation is conceptual change in science, more specifically, conceptual change in biology. The task of a discussion of conceptual change is the study of historical episodes in science so as to offer a philosophical account of how and why scien ...
A role for wingless in the segmental gradient of Drosophila?
... for 2.5 hours at 25°C, then aged 13.5 hours at 15°C, given a heatshock pulse and left at 15°C for 4 days. Although the resulting smooth phenotypes are more variable than those of embryos kept at 15°C all the time, we did not observe consistent differences between embryos with or without the HSwg con ...
... for 2.5 hours at 25°C, then aged 13.5 hours at 15°C, given a heatshock pulse and left at 15°C for 4 days. Although the resulting smooth phenotypes are more variable than those of embryos kept at 15°C all the time, we did not observe consistent differences between embryos with or without the HSwg con ...
FREE Sample Here
... 38) Why are relatively few inherited disorders caused by dominant alleles? A) Most disorders caused by dominant alleles lead to sterility, which means the dominant allele will not be passed on. B) Genetic testing can more readily identify dominant rather than recessive alleles; genetic counselling h ...
... 38) Why are relatively few inherited disorders caused by dominant alleles? A) Most disorders caused by dominant alleles lead to sterility, which means the dominant allele will not be passed on. B) Genetic testing can more readily identify dominant rather than recessive alleles; genetic counselling h ...
Haemophilia (2013) - Haemophilia Foundation Australia
... have another factor VIII or IX gene to help with blood clotting and will have haemophilia. If a male with haemophilia has children, all his daughters will carry the haemophilia gene because he will pass the altered factor VIII or IX gene on to them on his X chromosome. His sons will not have haemoph ...
... have another factor VIII or IX gene to help with blood clotting and will have haemophilia. If a male with haemophilia has children, all his daughters will carry the haemophilia gene because he will pass the altered factor VIII or IX gene on to them on his X chromosome. His sons will not have haemoph ...
List two characteristics of a mutant allele
... ANS Isolation of population/ Mutations occur/ Natural selection occurs / Speciation or new species formed List 3 ways to conserve endangered species ...
... ANS Isolation of population/ Mutations occur/ Natural selection occurs / Speciation or new species formed List 3 ways to conserve endangered species ...
Novel p53 mutants selected in BRCA
... the formation of meristems, and the mammalian NADPH-quinone oxidoreductase which is a potent inducer of reactive oxygen species (ROS) which are powerful inducers of apoptosis. The importance of transactivation in mediating the biological eects of p53 has been illustrated by studies of human tumour ...
... the formation of meristems, and the mammalian NADPH-quinone oxidoreductase which is a potent inducer of reactive oxygen species (ROS) which are powerful inducers of apoptosis. The importance of transactivation in mediating the biological eects of p53 has been illustrated by studies of human tumour ...
trigger - Bioconductor
... gene end for all the genes in the gene expression matrix. The rows of exp.pos should match those of exp. marker: A matrix with p rows and n columns, containing genotyping information. marker.pos: A matrix with p rows and 2 columns containing the chromosome number and SNP position for all the genes i ...
... gene end for all the genes in the gene expression matrix. The rows of exp.pos should match those of exp. marker: A matrix with p rows and n columns, containing genotyping information. marker.pos: A matrix with p rows and 2 columns containing the chromosome number and SNP position for all the genes i ...
Reproductive barriers in indica-japonica rice
... differentially expressed at MMC, MEI and AME. Large numbers of cell wall ...
... differentially expressed at MMC, MEI and AME. Large numbers of cell wall ...
Genetic and biochemical analysis of the adenylyl cyclase of
... In S. cerevisiae, expression of the regulatory amino terminal domain of adenylyl cyclase dominantly interferes with normal adenylyl cyclase activity, presumably by binding to regulatory proteins (Field et aL., 1990b). To test if expression of the amino terminal domain of adenylyl cyclase could simil ...
... In S. cerevisiae, expression of the regulatory amino terminal domain of adenylyl cyclase dominantly interferes with normal adenylyl cyclase activity, presumably by binding to regulatory proteins (Field et aL., 1990b). To test if expression of the amino terminal domain of adenylyl cyclase could simil ...
The role of tumor necrosis factor-alpha
... some cytokine gene polymorphisms were analyzed for susceptibility to the disease. The aim of this study was to investigate the role of tumor necrosis factor-alpha (TNF-α) -308 G/A and transforming growth factor-beta 1 (TGF-β1) –915 G/C polymorphisms in the development and clinical progression of chi ...
... some cytokine gene polymorphisms were analyzed for susceptibility to the disease. The aim of this study was to investigate the role of tumor necrosis factor-alpha (TNF-α) -308 G/A and transforming growth factor-beta 1 (TGF-β1) –915 G/C polymorphisms in the development and clinical progression of chi ...
Assessing the role of anammox in a nitrogen contaminated aquifer
... step is the reduction of nitric oxide to nitrous oxide. This reduction is interesting because the enzyme that catalyzes this reaction, nitric oxide reductase (nor), is the enzyme that creates formation of the dinitrogen bond between the two nitrogen atoms of nitrous oxide (Bothe et al., 2000). Nitro ...
... step is the reduction of nitric oxide to nitrous oxide. This reduction is interesting because the enzyme that catalyzes this reaction, nitric oxide reductase (nor), is the enzyme that creates formation of the dinitrogen bond between the two nitrogen atoms of nitrous oxide (Bothe et al., 2000). Nitro ...
Tansley Review No. 103 Biological clocks in
... that carry light signals to reset the oscillator (change its phase), and the output pathways, which carry timing signals from the oscillator to clock-regulated processes in the cell. This has been a very useful, heuristic model, but it is increasingly clear that the biological mechanisms might blur ...
... that carry light signals to reset the oscillator (change its phase), and the output pathways, which carry timing signals from the oscillator to clock-regulated processes in the cell. This has been a very useful, heuristic model, but it is increasingly clear that the biological mechanisms might blur ...
Current Trends of Emergence and Spread of Vancomycin
... 3.4 Resistance to macrolides, lincosamides and streptogramin B (MLSB) Resistance to MLSB antibiotics is encoded by the widespread erm(B) gene and only occasionally via erm(A) or erm(C)(Roberts et al., 1999). Erm (“erythromycin resistance methylases”) confer resistance by modifying nucleotide A2058 o ...
... 3.4 Resistance to macrolides, lincosamides and streptogramin B (MLSB) Resistance to MLSB antibiotics is encoded by the widespread erm(B) gene and only occasionally via erm(A) or erm(C)(Roberts et al., 1999). Erm (“erythromycin resistance methylases”) confer resistance by modifying nucleotide A2058 o ...
Cytogenetic Analysis Shows that the Unusually Large Chromosome
... (black larval marking) silkworm (Bombyx mori) strain (TWPB). We have analyzed the composition and arrangement of this large chromosome. A genetic linkage analysis shows that the large chromosome is made up of the W chromosome, the second chromosome fragment (p fragment), and the fifth chromosome (li ...
... (black larval marking) silkworm (Bombyx mori) strain (TWPB). We have analyzed the composition and arrangement of this large chromosome. A genetic linkage analysis shows that the large chromosome is made up of the W chromosome, the second chromosome fragment (p fragment), and the fifth chromosome (li ...
Evolvable Hardware: By Antony Savich
... Need to map a circuit description (phenotype) to an evolutionary technique description (genotype) How do we represent a circuit? ...
... Need to map a circuit description (phenotype) to an evolutionary technique description (genotype) How do we represent a circuit? ...
Arabidopsis onset of leaf death mutants identify a regulatory
... old2 in Col-0 (Table 1). These characteristics make mapping a rather time-consuming process. The old2 mutant belongs to Class II early leaf senescence mutants, and among 12 mutants isolated 6 showed similar phenotypes and complex genetic behaviour, including the presence of a dominant suppressor in ...
... old2 in Col-0 (Table 1). These characteristics make mapping a rather time-consuming process. The old2 mutant belongs to Class II early leaf senescence mutants, and among 12 mutants isolated 6 showed similar phenotypes and complex genetic behaviour, including the presence of a dominant suppressor in ...