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Mcp7, a meiosis-specific coiled-coil protein of fission yeast
Mcp7, a meiosis-specific coiled-coil protein of fission yeast

... mnd1-null mutant arrests in meiotic prophase with most DSBs unrepaired and homolog pairing severely reduced (23). Mnd1 is suggested to be involved in strand invasion since mnd1-1 mutant cells initiated recombination but did not form heteroduplex DNA or Holliday junctions (24). We report here the fun ...
fog-1, a Regulatory Gene Required for Specification of
fog-1, a Regulatory Gene Required for Specification of

... In wild-type Caenorhabditis elegans, the X 0 male germ line makes only sperm and the XX hermaphrodite germ line makes sperm and then oocytes. In contrast, the germ line of either a male or a hermaphrodite carrying a mutation of the fog-1 (feminization of the germ line) locus is sexually transformed: ...


... between genetic variants and bacterial colonisation on a diagnosis were tested based on biological conceivability: TLR2 (rs3804099 and rs4696480) with gram-positive bacteria (S. pneumoniae and S. aureus); TLR4 (rs2737190) and CD14 (rs2569190) with gram-negative bacteria (H. (para)influenzae). In add ...
Gene Regulation and Systems Biology GA
Gene Regulation and Systems Biology GA

... Abstract: In the past decade, the development of synthetic gene networks has attracted much attention from many researchers. In ­particular, the genetic oscillator known as the repressilator has become a paradigm for how to design a gene network with a desired dynamic behaviour. Even though the repr ...
S2 File.
S2 File.

... Fig A: Results of optical density measurement (top) and the crystal violet assay (bottom) for replicates (n = 3) of the wells that were harvested for RNA sequencing. Wells without NaCl addition were harvested after 1 day of incubation, while wells with NaCl addition were harvested after 2 days, to ...
Lec17_heritability
Lec17_heritability

... (bell curve) ...
Highly Recurrent RET Mutations and Novel Mutations in
Highly Recurrent RET Mutations and Novel Mutations in

... live births) (1 ). The M:F ratio is ⬃4:1 for SSA-HSCR patients and ⬃1:1 for LSA-HSCR patients (1 ). Approximately 20% of HSCR cases are familial. The recurrence risk for siblings of SSA-HSCR probands varies from 1.5% to 3.3%, whereas the risk for siblings of LSA-HSCR probands varies from 3% to 18% ( ...
Chromosome intermingling—the physical basis of chromosome
Chromosome intermingling—the physical basis of chromosome

... Although chromosome length and gene density may guide the radial organization of CTs, these factors remain constant across multiple cell types in an organism, and hence, are insufficient to explain the cell typespecific organization of CTs. 3C data have uncovered intrachromosome interactions that re ...
The hidden complexity of Mendelian traits across yeast
The hidden complexity of Mendelian traits across yeast

... Hidden complexity of a rare Mendelian variant across different genetic backgrounds While focusing on highly frequent cases such as CuSO4 and NaCl provided indications about the transmission stability of common Mendelian variants and revealed previously unknown co-segregations, we were particularly i ...
Measuring the effect of inbreeding on reproductive success in a
Measuring the effect of inbreeding on reproductive success in a

... Sexual conflict is one of the major causes for speciation. Even if natural selection guides some penetrant alleles to become highly preferred, sexual conflicts can cause the reduction of the fitness in the same alleles in another sex (Mayr et al. 2005). This antagonistic interaction is detectable no ...
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PDF

Untitled - System Components
Untitled - System Components

... (Grundlage) of photoperiodism, investigators have sought physiological parallelisms between circadian behavior and photoperiodic response. With a deeper understanding of the molecular basis of circadian rhythmicity in Drosophila melanogaster, circadian rhythm genes quickly became candidate loci for ...
DNA Polymorphisms in the β-lactoglobulin and κ–casein Genes
DNA Polymorphisms in the β-lactoglobulin and κ–casein Genes

... ionization time of flight mass spectrometry (MALDI-TOF) and DNA sequencing methods in 752 individuals from Chinese Holstein cattle breeds. A single nucleotide polymorphism (g.1810C>T) in exon III in β-lactoglobulin gene and two single nucleotide polymorphisms (g.10888T>C and g.12703G>T) in exon IV a ...
Breast Cancer - Deanna Bennett
Breast Cancer - Deanna Bennett

what is tuberous sclerosis
what is tuberous sclerosis

... 2. It is a rare genetic disease that is multi-system, in other words, it affects many of the body’s different organ systems. 3. Tuberous sclerosis causes benign tumors to grow in the brain and other organs such as the kidneys, heart, eyes, and lungs and on the skin. ...
Chapter 17 Section 1: Genetic Variation
Chapter 17 Section 1: Genetic Variation

Gene Mutations Caused by Radiation
Gene Mutations Caused by Radiation

... also to the determination of the spectra of both spontaneous and induced mutations to be obtained under given conditions, as in different cell stages, on application of chosen chemicals, in various physiological states, and in the presence of particular genes. But, although no such exact comparison ...
number of fifty human tumours
number of fifty human tumours

... uteri (Atkin, 1964b). In contrast, chromosome studies demand material containing adequate numbers of dividing cells (not always present in small samples of human tumour material) and furthermore are subject to the vagaries of presentday techniques for chromosome spreading: metaphases may be poorly s ...
11.3.2005 Official Journal of the European Union L 65/39
11.3.2005 Official Journal of the European Union L 65/39

... To be able to establish itself in the environment a GMM would have to survive dispersal to, and establish itself in, a suitable niche. Consideration should be given to the method of dispersal and the likelihood of survival during dispersal. Many micro-organisms survive, for example, when dispersed i ...
1 X chromosome crossover formation and genome stability in
1 X chromosome crossover formation and genome stability in

... histone H2A (H2AK5ac) is emerging as a vital player in these processes. In xnd1 mutant germ lines, an increase in H2AK5ac was associated with decreased DSB formation, especially on the X chromosome (WAGNER et al. 2010; GAO et al. 2015). H2AK5ac levels are diminished in htp-3 mutants and, in late pac ...
Chapter 15 Test - cloudfront.net
Chapter 15 Test - cloudfront.net

... C) genes D) heredity 19. The scientific study of heredity is called __________. A) Genetics B) alleles C) genes D) Homozygous 20. True or False: Organisms produced by sexual reproduction receive half of their DNA from the female parent and the other half from the male parent A) True B) False 21. Tru ...
Two Anthranilate Synthase Genes in Arabidopsis
Two Anthranilate Synthase Genes in Arabidopsis

... 2B) and confirmed by S1 nuclease protection (data not shown). For ASA1 mRNA, there are two major 5' ends, resulting in 5' untranslated leaders of 90 and 93 nucleotides. The mRNA corresponding to ASA2 begins at a single site 41 nucleotides upstream of the first AUG codon. As determined by cDNA sequen ...
Leukaemia Section i(17q) solely in myeloid malignancies Atlas of Genetics and Cytogenetics
Leukaemia Section i(17q) solely in myeloid malignancies Atlas of Genetics and Cytogenetics

... Testa JR, Cohen BC. Dicentric chromosome 17 in patients with leukemia. Cancer Genet Cytogenet. 1986 Sep;23(1):47-52 ...
Articles - American Scientist
Articles - American Scientist

... genetic pickpockets, grabbing genes to occur through faces of the viral capCentral to the placement of giant vi- from their hosts over eons. Interpreta- sid that are not the stargate—DNA enruses in the tree of life is the presence tion of viral phylogenetic reconstruc- try into and exit from the vir ...
Symbiotic DNA in eukaryotic genomes
Symbiotic DNA in eukaryotic genomes

... presence of the same sequence The evolutionary relationship be at several locations, and by the tween these mobile elements and the genomes they inhabit recombinogenic nature of most transposition mechanisms. is one of the most intriguing aspects of molecular genetics. Chromosomal instability result ...
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Genome (book)

Genome: The Autobiography of a Species in 23 Chapters is a 1999 popular science book by Matt Ridley, published by Fourth Estate.
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