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Chromosomal translocations deregulated BCL6
Chromosomal translocations deregulated BCL6

... lymphoma (Tweeddale et al., 1987). In all three cases, the involvement of the BCL6 locus in the translocation was confirmed by a cytogenetic analysis and by evidence of a rearranged BCL6 allele upon Southern blot analysis of the genomic DNA (data not shown). For cases SM1444 and KC1445, the cloning ...
The genetics of Caenorhabditis elegans.
The genetics of Caenorhabditis elegans.

... (JUDD, SHENand KAUFMAN 1972). Although there are many theories suggesting how the extra DNA might be used for complex genetic regulation (BRITTEN and DAVIDSON 1969; GEORGIEV 1969; CRICK 1971), the problem is still opaque. We know very little about the molecular mechanisms used to switch genes on and ...
p53, the Cellular Gatekeeper Review for Growth and Division
p53, the Cellular Gatekeeper Review for Growth and Division

... some suggestions that the missense mutant producing a faulty p53 protein could contribute a “gain of function” phenotype (Dittmer et al., 1993), but this remains to be substantiated by additional experimentation. A study of the mutational spectra at the p53 locus in different tissue types indicates ...
A Single Eubacterial Origin of Eukaryotic
A Single Eubacterial Origin of Eukaryotic

... were used to amplify a fragment of 1,539 bp, which was cloned into pGEMT (Promega). Two clones were sequenced on both strands. To distinguish between this PCR product and the published G. lamblia PFO gene sequence, we refer to the published sequence as G. lamblia PFO1 and to the gene represented by ...
Polymorphic mimicry in Papilio dardanus: mosaic
Polymorphic mimicry in Papilio dardanus: mosaic

... We were also able to obtain a sufficiently large sample of females from two mimicking forms, cenea and hippocoonides, of the race polytrophus for correlation analysis. In these forms the color pattern is more complicated in that in each wing cells there are two black patterns: a distal pattern that ex ...
Bacterial canker and blast of stone fruit trees, caused by
Bacterial canker and blast of stone fruit trees, caused by

... 7% instead of 5% sucrose and incubated at 30 deg C, or subculturing 30-day-old colonies on NSA, resulted in the appearance of clear, waterdrop-like colony variants. These variants did not induce the hypersensitivity reaction in tobacco leaves. This colony type was occasionally observed on NSA during ...
Primer on Molecular Biology
Primer on Molecular Biology

... • Human genome is around 3 billions base pair long • Almost every cell in human body contains same set of genes • But not all genes are used or expressed by those cells ...
UCSD_PevznerMolecula.. - Purdue University :: Computer Science
UCSD_PevznerMolecula.. - Purdue University :: Computer Science

DNA
DNA

... • Human genome is around 3 billions base pair long • Almost every cell in human body contains same set of genes • But not all genes are used or expressed by those cells ...
Student Handout
Student Handout

... teosinte and maize look like very different plants. It seemed unlikely that teosinte would give rise to maize within the 10,000 years or so that humans had been growing crops, because the process would involve changes in many genes—too many to occur in this time span. Dr. Beadle’s experiment set out ...
Primer on Molecular Biology
Primer on Molecular Biology

... • Human genome is around 3 billions base pair long • Almost every cell in human body contains same set of genes • But not all genes are used or expressed by those cells ...
View our poster (1.1 MB PDF)
View our poster (1.1 MB PDF)

... Figure 1. RNA interference (RNAi) is a highly evolutionarily conserved mechanism of gene regulation. RNAi occurs at the post-transcriptional level and is triggered by short double-stranded RNA (dsRNA), known as short interfering RNA (siRNA), which is endogenously processed from long dsRNA by the RNa ...
i A Thesis Entitled A Visual Screen for Centriolar Mutants in
i A Thesis Entitled A Visual Screen for Centriolar Mutants in

... mammalian CPAP in cell culture leads to centriole over-elongation (Kohlmaier 2009; Schmidt 2009; Tang 2009). Bld10/CEP135 and Poc1/POC1 are centriolar proteins recruited to the centriole around the same time as Sas4/CPAP. These proteins stabilize centrioles likely through direct binding of centriol ...
The Backyard Geneticist
The Backyard Geneticist

... This drastic little fable is an exaggeration--but not much of one. Here’s similar, though less drastic, example from real life: There once was a Quarter Horse stallion named Impressive. The name fit. He sired many foals who also exhibited his desired traits. But when they and their descendants were ...
Imputation-Based Fine-Mapping Suggests that Most QTL in an
Imputation-Based Fine-Mapping Suggests that Most QTL in an

... effects of long-term (more than 50 generations), divergent, single-trait selection for 56-day ...
Reproductive barriers in indica-japonica rice
Reproductive barriers in indica-japonica rice

... the functional allele of each gene is indicated with “+” while the non-functional allele ...
3.1.molecular_evolution - T
3.1.molecular_evolution - T

... (or “clocklike”) and because selection does not influence the rate of divergence, divergence of DNA and protein molecules in two separate lineages should occur in a REGULAR, clocklike manner ...
Biopsychology, 7e (Pinel) - College Test bank
Biopsychology, 7e (Pinel) - College Test bank

... D) that used tools. E) all of the above Answer: A Diff: 2 Page Ref: 34 Topic: 2.2 Human Evolution 61) Mendel A) studied dichotomous pea-plant traits. B) began his experiments by crossing the offspring of true-breeding lines. C) collaborated with Darwin. D) all of the above E) both A and B Answer: E ...
Recruitment of CRABS CLAW to promote nectary development
Recruitment of CRABS CLAW to promote nectary development

... The nectary provides an interesting example with which to address this question owing to its diversity in both structure and ontogeny. Nectaries are highly variable in their morphologies, anatomies and locations, and are defined based on their shared function: the secretion of nectar (Fahn, 1979). D ...
Interferon Gamma Gene Polymorphism as a Biochemical Marker in
Interferon Gamma Gene Polymorphism as a Biochemical Marker in

... The development of atopy depends on several genes, and disease expression is influenced by exposure to environmental factors. Several genome-wide searches have linked the development of atopy to different autosomal chromosomal regions, many of which directly or indirectly regulate IgE production and ...
Apical-basal pattern formation in the Arabidopsis
Apical-basal pattern formation in the Arabidopsis

... (RF) using the mapping function. RF values were determined as RF=x/(2−x) where x is the proportion of gnom heterozygous among all F2 plants showing the same marker phenotype. As a control, the RF value for an - dis-1 was calculated: x=(1−RF)2 where x is the proportion of an dis-1 among all F2 plants ...
Mapping Polygenes - University of Warwick
Mapping Polygenes - University of Warwick

... linkage between molecular markers and genes controlling quantitative traits (34, 43, 52, 55, 62). In species where severe inbreeding is tolerated, recombinant inbred populations (derived by inbreeding F2 progeny until they become virtually homozygous lines by selfing or sibbing) have also been used ...
the full article - Medical Writing
the full article - Medical Writing

... for obesity-related traits (BMI, WC, WH ratio, body fat percentage, and extreme-early onset obesity) led to the discovery of 52 robust loci.24,26 For BMI, 32 loci reaching genome-wide significance have been identified for white European-type adults. Of the 32 loci identified by Speliotes et al.,27 e ...
Isolation, Characterization and Complementation
Isolation, Characterization and Complementation

... In summary, only two of the mutant classes described by Abou-JaoudC et al. (1978a) were deficient in their ability to reduce nitrite and only the nirD strain was defective in NADHdependent nitrite reductase activity. The phenotype of LCB82 was identical to that of strain JCB203, but although both of ...
Granato 1996
Granato 1996

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Genome (book)

Genome: The Autobiography of a Species in 23 Chapters is a 1999 popular science book by Matt Ridley, published by Fourth Estate.
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