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Bipolar disorder and disruptive mood
Bipolar disorder and disruptive mood

... placebo-controlled trials in youth BD established that atypical antipsychotics have better efficacy and tolerability compared with anticonvulsants and lithium (effect size atypical antipsychotics 0.65, CI 0.53 to 0.78 vs anticonvulsants and lithium 0.24, 95% CI 0.06 to 0.41). Particularly in youth, a ...
Depression
Depression

... 2. Treatment Options: a) Medication (SSRI, SNRI, Bupropion, Mirtazipine, TCA, and MAOI) If patient is started on medication they must be monitored weekly for suicidal ideation for 4 to 6 weeks. Note: anxiety and depression often co-exist so treatment of depression can unmask anxiety disorder and unr ...
Psychiatric use of drugs
Psychiatric use of drugs

... • First-generation antipsychotic drugs have been effective in reducing symptoms for many patients, but they also carry the potential for the development of severe movement-related motor problems. • Second-generation and third-generation antipsychotic medications do not produce this particular side e ...
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Illegal Drugs - Texarkana Independent School District
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Antipsychotic Use in Children and Adolescents: Minimizing Adverse Effects to Maximize Outcomes
Antipsychotic Use in Children and Adolescents: Minimizing Adverse Effects to Maximize Outcomes

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... Choice of typical antipsychotics depot2 There are few differences between individual first generation antipsychotics depots. However, Zuclopenthixol Decanoate may be more effective in prevention relapses although this may be at the expense of increased burden of side-effect. Flupenthixol Decanoate c ...
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... dopaminergic drugs has generally been the first step in the treatment of hallucinosis or delusions in PD when at all possible. • Classic neuroleptic drugs are best avoided but there are reports that atypical antipsychotic drugs such as risperidone or olanzapine,are useful. ...
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The Use of Antipsychotic Medications in Nursing Home
The Use of Antipsychotic Medications in Nursing Home

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... DNA sequence (polymorphisms) in genes that have been implicated by the known pharmacology and neurochemical mechanisms of these drugs (reviewed in [4]). The target receptors for the antipsychotic drugs thus provide valuable ‘‘candidate’’ genes. It is the dopamine D2 receptor that is considered the m ...
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... retrospect, the terms “ultra high-risk” or “clinical highrisk” or “At Risk Mental State” (ARMS) are used. The first results of these projects have indicated that ARMS individuals are indeed at imminent risk of psychosis, with transition rates ranging from 15% to 54% after 6 months to 1 year (e.g. Ha ...
Geriatric Giants, Day 1 - Acute Care Geriatric Nurse Network
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... depression, suicide attempts, family Hx • Differentiate Dx of type of mood/affective disorder from chronic dysthymia. SUICIDE • Physical to r/o medical cause (e.g.thyroid) • Labs - same as antipsychotics • Referral to appropriate psychiatrist ...
280KB, PPT
280KB, PPT

...  Schizophrenia has a course that is chronic and, if not deteriorating, is stable and usually nonremitting.  Positive symptoms (e.g., hallucinations and delusions) “burn out” over time and are replaced by increasing negative symptoms (e.g., reduced affective experience and expression and reduced ...
Overview of the Brain and Psychiatric Illnesses by Dr. Daniel Healy
Overview of the Brain and Psychiatric Illnesses by Dr. Daniel Healy

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Antipsychotic



Antipsychotics (also known as neuroleptics or major tranquilizers) are a class of psychiatric medication primarily used to manage psychosis (including delusions, hallucinations, or disordered thought), in particular in schizophrenia and bipolar disorder, and are increasingly being used in the management of non-psychotic disorders (ATC code N05A). The word neuroleptic originates from the Greek word νεῦρον neuron (""nerve"") and λῆψις lepsis (""seizure"", ""fit"", ""occupation"").First-generation antipsychotics, known as typical antipsychotics, were discovered in the 1950s. Most second-generation drugs, known as atypical antipsychotics, have been developed more recently, although the first atypical antipsychotic, clozapine, was discovered in the 1950s and introduced clinically in the 1970s. Both generations of medication tend to block receptors in the brain's dopamine pathways, but atypicals tend to act on serotonin receptors as well.Antipsychotics are more effective than placebo in treating symptoms of psychosis, but some people do not respond fully or even partly to treatment. Their use is associated with significant side effects, most notably movement disorders and weight gain.
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