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1903. - Sutton, Walter S. The chromosomes in heredity. Biological
1903. - Sutton, Walter S. The chromosomes in heredity. Biological

... they represent. In other words, it is probable that specific differences and individual variations are alike traceable to a common source, which is a difference in the constitution of homologous chromatin entities. Slight differences in homologues would mean corresponding, slight variations in the c ...
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Cell Division (Meiosis)

... nonsister chromatids at the chiasmata. • Crossing over: segments of nonsister chromatids break and reattach to the other ...
Ch14_Genetics
Ch14_Genetics

... carbohydrates to red blood cells: IA, IB, and i. • The enzyme encoded by the IA allele adds the A carbohydrate, whereas the enzyme encoded by the IB allele adds the B carbohydrate; the enzyme encoded by the i allele adds neither ...
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disorder - Cloudfront.net

... Dd Disorder ...
P.Point Lecture Template - Green River Community College
P.Point Lecture Template - Green River Community College

... where tongue rolling is dominant to non-rolling. What is the chance that the couple will produce a girl that is a non-roller? Use the following steps as a general guide to solve this and other problems: 1. Select a letter to represent the gene involved • Use upper case for the dominant allele, lower ...
Meiosis
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... that is, the material breaks off and reattaches at the same  position on the homologous chromosome.  This is like  cutting and pasting pieces of chromosomes.  As long as  the same area is cut and pasted on each chromosome, the  children can end up with “grandpa’s eyes” and “grandma’s  nose” kind of  ...
cell cycle - Montville.net
cell cycle - Montville.net

... When a chromosome is examined during mitosis or meiosis there is a pinched in region somewhere along the length of the chromosome called the centromere. The centromere is a region to which the spindle fibers attach to the chromosome and it is in a characteristic position that is constant for differe ...
Chapter 12 The Chromosomal Basis of Inheritance
Chapter 12 The Chromosomal Basis of Inheritance

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... Cri-du-chat syndrome, Klinefelter syndrome, triplo-X- syndrome Klinefelter syndrome, triplo-X- syndrome, Supermale syndrome Incheritance of a dominant autosomal disorder differs from incheritance of an autosomal recessive disorder in that: A Dominant disorder may be passed on only if both parents ar ...
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DETERMINING THE BEST MUTATION PROBABILITIES OF A

... to find a better solution. Our goal is to further improve the aforementioned algorithm by finding the optimal probabilities for the mutation methods. The GA3SM algorithm uses the following mutation steps: 1. Select a processor: a) Randomly, b) With the biggest total execution time. 2. Select a task ...
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... still need to understand how heterochromatic domains of gene expression are organized and what accounts for the differences between heterochromatic and euchromatic domains. To this regard it is worth noting that active heterochromatic genes might show a nucleosome array characteristic of euchromatin ...
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Chromosome intermingling—the physical basis of chromosome
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... Although chromosome length and gene density may guide the radial organization of CTs, these factors remain constant across multiple cell types in an organism, and hence, are insufficient to explain the cell typespecific organization of CTs. 3C data have uncovered intrachromosome interactions that re ...
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... planet called ZORK. The inhabitants were known as Zorkonians. They are made up of 10 basic genes (unit) that code for their appearance. Each one of these genes is made up 2 alleles (traits). With this in mind, there are 1,024 different possible combinations for their appearance! This is called their ...
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Effects of linkage on response to directional selection from new

... in the model had to be specified, for example the number of loci, the effects and initial frequency of each gene and, in most cases, the recombination fraction between adjacent loci. In our model all that have to be specified, in addition to the basic assumption of additive gene action, are: (i) the ...
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Case study: maintenance scheduling

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... 1. From the wide variety of mutational possibilities for most genes, we can usually distinguish only functional and non-functional alleles. 2. The functional allele is usually dominant to the non-functional allele in individuals with both alleles (heterozygote). 3. Offspring from heterozygous parent ...
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Print - Circulation Research

... Recently, we have demonstrated the expression of nonmuscle myosin in restenotic lesions in human coronary as well as peripheral arteries.25 The appearance of the nonmuscle isoform correlates with the newly acquired ability of smooth muscle cells to divide and disappears when cells return to their co ...
Caspary T, Cleary MA, Baker CC, Guan XJ, Tilghman SM. Mol Cell Biol. 1998 Jun;18(6):3466-74. Multiple mechanisms of imprinting on distal mouse chromosome 7.
Caspary T, Cleary MA, Baker CC, Guan XJ, Tilghman SM. Mol Cell Biol. 1998 Jun;18(6):3466-74. Multiple mechanisms of imprinting on distal mouse chromosome 7.

... contains a cluster of four maternally expressed genes, H19, Mash2, Kvlqt1, and p57Kip2, as well as two paternally expressed genes, Igf2 and Ins2, and assess the expression and imprinting of Mash2, Kvlqt1, and p57Kip2 during development in embryonic and extraembryonic tissues. Unlike Igf2 and Ins2, w ...
Reconstruction of a 450-My-old ancestral vertebrate protokaryotype
Reconstruction of a 450-My-old ancestral vertebrate protokaryotype

... Chromosomal painting techniques (Zoo–FISH analysis) This technique relies on DNA sequence similarity, which is revealed by fluorescence in situ hybridization (FISH) techniques. Preferably, DNA probes from single chromosomes are used, which under prolonged hybridization indicate the orthologous chrom ...
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Skewed X-inactivation

Skewed X chromosome inactivation occurs when the inactivation of one X chromosome is favored over the other, leading to an uneven number of cells with each chromosome inactivated. It is usually defined as one allele being found on the active X chromosome in over 75% of cells, and extreme skewing is when over 90% of cells have inactivated the same X chromosome. It can be caused by primary nonrandom inactivation, either by chance due to a small cell pool or directed by genes, or caused by secondary nonrandom inactivation, which occurs by selection. Most females will have some levels of skewing. It is relatively common in adult females; around 35% of women have skewed ratio over 70:30, and 7% of women have an extreme skewed ratio of over 90:10. This is of medical significance due to the potential for the expression of disease genes present on the X chromosome that are normally not expressed due to random X inactivation. X chromosome inactivation occurs in females to provide dosage compensation between the sexes. If females kept both X chromosomes active they would have twice the number of active X genes than males, who only have one copy of the X chromosome. At approximately the time of implantation (see Implantation (human embryo), one of the two X chromosomes is randomly selected for inactivation. The cell undergoes transcriptional and epigenetic changes to ensure this inactivation is permanent. All progeny from these initial cells will maintain the inactivation of the same chromosome, resulting in a mosaic pattern of cells in females.
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