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... I), each homologous pair of chromosomes lines up at the equator in random order (remember that homologous pairs can have different alleles for a certain gene). • Spindle microtubules attach to whichever chromosome is closest. • Each pole is equally likely to receive either chromosome. • In humans, t ...
Genetics - Valhalla High School
Genetics - Valhalla High School

... the case where three or more alleles of the same gene exist. Remember, an organism will have only two of these alleles (one from mom and one from dad). – Examples: Coat color in rabbits, blood type in humans ...
doc Summer 2010 Lecture 3
doc Summer 2010 Lecture 3

... There are a number of genes in the mtDNA - many involved with energy production - some play roles in heredity - chromosomal inheritance is 50% male and 50% female - organelle DNA: male contribution is low o random distribution—no spindle dividing it  get a segregation of mitochondria into 2 daughte ...
Multiple Alleles and Polygenic Inheritance
Multiple Alleles and Polygenic Inheritance

... The human Y chromosome is much smaller and appears to contain only few genes. Father determines the sex of the offspring The chance is always 50-50 for either sex A recessive gene has no matching gene on the Y More Sex linked disorders are found in males ...
genetics_4
genetics_4

... • Phenotypic ratio = 2 Black: 2 Red ...
Additional traits
Additional traits

... Beyond Mendel’s Laws of Inheritance ...
2 cp u9 inheritance notes
2 cp u9 inheritance notes

... – Who will show more X-linked disorders, males or females? Why? • Males – b/c they only have one X (XY) so it doesn’t matter if trait is dominant or recessive – Examples: • Colorblindness – carried on X-chromosome • Hemophilia – impaired blood clotting ...
b - nnhschen
b - nnhschen

... The Chromosomal Basis of Sex • In humans and other mammals: X vs. Y • Y is tiny!! • The SRY gene on the Y chromosome • Some disorders caused by recessive alleles on the X: • Color blindness (mostly X-linked) • Duchenne muscular dystrophy • Hemophilia ...
Genetics Study Guide
Genetics Study Guide

...  Allele: Different forms of a gene.  Dominant allele: The allele that is always expressed if it is present. Recessive allele: The allele that is expressed only if the dominant allele is not present.  Punnett Square: A tool used to visualize all the possible combination of alleles from the parents ...
Mendel’s Laws of Heredity
Mendel’s Laws of Heredity

... different traits.  Each gene on one chromosome of the pair has a similar gene on the other chromosome of the pair.  Each gene of a gene pair is called an allele (uh LEEL) ...
Mutations - year13bio
Mutations - year13bio

... to a stop codon resulting in a shorter, usually nonfunctional protein. ...
Unit Plan Assessments
Unit Plan Assessments

... 1. The different forms of a gene are called_________. a. Traits b. Alleles c. Hybrids d. Homozygous 2. Who is the father of genetics? a. Einstein b. Darwin c. Watson d. Mendel 3. If a pea plant’s alleles for height are tt, what is true of its parents? a. Both parents contributed a dominant allele b. ...
Period 5 1. In Trisomy X Syndrome, what is the abnormality? a. An
Period 5 1. In Trisomy X Syndrome, what is the abnormality? a. An

... The division of the cell nucleus and its contents The creation of offspring from a single parent and does not involve the joining of gametes The regular pattern of growth, DNA duplication, and cell division that occurs in eukaryote cells d. The process that divides the cell cytoplasm ...
Algorithms for Genetics: Introduction, and sources of
Algorithms for Genetics: Introduction, and sources of

... and P(ab)), then these combinations can be treated as multiple alleles at a single locus. Applying the HW equilibrium to multiple alleles at a single locus is described above. * If we assume an infinite size population with random mating, the allele frequency does not change from generation to gener ...
Genetics - Georgia Highlands College
Genetics - Georgia Highlands College

... Autosomal Disorders • Dominant – Rare because always expressed  embryo/fetal death – Huntington’s disease: impairs motor functioning • Onset after reproductive age, increase probability of passing ...
Please Take Out The Following: Pencil Science Journal Chapter 8
Please Take Out The Following: Pencil Science Journal Chapter 8

... Answer When alleles for different characteristics are on separate chromosomes, they are distributed to gametes separately. This is known as: The Law of Independent Assortment *Mendel's Law of Independent Assortment - The alleles of the many different genes present in any given (diploid) organism se ...
Perspectives on the Medical and Genetic Aspects
Perspectives on the Medical and Genetic Aspects

... developmental genes in 13, 18, 21, so all three are live born with a full third chromosome. However, there is substantial fetal loss. Half of those identified with having trisomy 13 before 20 weeks are still born. Fetal loss is not so great with Down syndrome. The genes in chromosomes number 1, 2, 3 ...
Separated Twins
Separated Twins

... • Forgetfulness, tremors, jerky motions, loss of ability to talk, temper tantrums, blindness, death • Onset after 30 • Lab tests can identify the gene itself, but not its marker… ...
RW - My CCSD
RW - My CCSD

...  The 23rd pair of chromosomes are XX for a female and XY for a male.  Mom can only pass on her X chromosome, but dad can pass X or Y.  Dad determines if offspring is male or female.  Dads give their Y to sons, Moms always give their X to their sons Sex linked traits-traits on this pair of chromo ...
chapter_16
chapter_16

... Nullisomy = loss of one homologous chromosome pair. Monosomy = loss of a single chromosome. Trisomy = one extra chromosome. ...
Wide-spread polyploidizations during plant evolution Dicot
Wide-spread polyploidizations during plant evolution Dicot

... Figure 3. Progression of rearrangem ent s and chromoso me fusions leading t o t he loss of a cent romere in Z. rouxii. Two non-reciprocal telomeric translocations and a telomere-to-telomere fusion gave rise to the extant chromosome structures in Z. rouxii. Chromosomes in green boxes are those that u ...
Chromosomal Basis of Inheritance
Chromosomal Basis of Inheritance

... Hemizygous - 1 copy of X chromosome. Show ALL X traits (dominant or recessive). More likely to show X recessive gene problems than females. ...
The Chromosomal Basis of Inheritance
The Chromosomal Basis of Inheritance

... chromosome. Testcrosses show that the recombination frequency between A and B is 28% and between A and C is 12%. A’s in the middle! Can you determine the linear order of these genes are their relative distance from each other in map units? ...
Lecture 4 pdf
Lecture 4 pdf

... - low (incomplete) penetrance some people with a particular genotype do not show the expected phenotype 60% with Aa show expected phenotype (ie allele is penetrant in these people) 40% with Aa do not show expected phenotype (ie. allele is not penetrant in these people) Penetrance of this allele = 60 ...
Study Guide 1-10
Study Guide 1-10

... Define and DRAW Crossing-over. When does crossing over occur? ...
< 1 ... 164 165 166 167 168 169 170 171 172 ... 241 >

Skewed X-inactivation

Skewed X chromosome inactivation occurs when the inactivation of one X chromosome is favored over the other, leading to an uneven number of cells with each chromosome inactivated. It is usually defined as one allele being found on the active X chromosome in over 75% of cells, and extreme skewing is when over 90% of cells have inactivated the same X chromosome. It can be caused by primary nonrandom inactivation, either by chance due to a small cell pool or directed by genes, or caused by secondary nonrandom inactivation, which occurs by selection. Most females will have some levels of skewing. It is relatively common in adult females; around 35% of women have skewed ratio over 70:30, and 7% of women have an extreme skewed ratio of over 90:10. This is of medical significance due to the potential for the expression of disease genes present on the X chromosome that are normally not expressed due to random X inactivation. X chromosome inactivation occurs in females to provide dosage compensation between the sexes. If females kept both X chromosomes active they would have twice the number of active X genes than males, who only have one copy of the X chromosome. At approximately the time of implantation (see Implantation (human embryo), one of the two X chromosomes is randomly selected for inactivation. The cell undergoes transcriptional and epigenetic changes to ensure this inactivation is permanent. All progeny from these initial cells will maintain the inactivation of the same chromosome, resulting in a mosaic pattern of cells in females.
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