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ch 13 and genetic disorders
ch 13 and genetic disorders

... -there is a chance that half of the zygotes will be 46XX and half will be 46XY -all egg cells carry a single X chromosome -however, half of all sperm cells carry an X chromosome and half carry a Y -human chromosomes contain both protein and a single, double-stranded DNA molecule -many human genes ha ...
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... is the division of the cytoplasm to make two new cells. The 2 new cells that are formed from Meiosis I are because they contain half of the chromosome of the original cell that started meiosis. At the start of Meiosis I you had 1 cell. Meiosis II must take place because each of our new cells still h ...
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... In order to escape the cellular mechanisms that detect and repair damaged DNA, the ends of our chromosomes are covered by molecular ʻcapsʼ called telomeres. These complexes, formed of proteins and repetitive DNA, constitute an ʻanti-enzyme shieldʼ that protects chromosome ends. Inadvertent end joini ...
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... Klinefelters individuals, increases dramatically at some point beyond “normal” reproductive age, but only in females; inflection point in human females is around 40 years of age 1. Essentially a “storage effect -- sperm are turned over every 20 or so days, whereas eggs are generated, held at meiosis ...
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Polyploid



Polyploid cells and organisms are those containing more than two paired (homologous) sets of chromosomes. Most species whose cells have nuclei (Eukaryotes) are diploid, meaning they have two sets of chromosomes—one set inherited from each parent. However, polyploidy is found in some organisms and is especially common in plants. In addition, polyploidy occurs in some tissues of animals that are otherwise diploid, such as human muscle tissues. This is known as endopolyploidy. Species whose cells do not have nuclei, that is, Prokaryotes, may be polyploid organisms, as seen in the large bacterium Epulopicium fishelsoni [1]. Hence ploidy is defined with respect to a cell. Most eukaryotes have diploid somatic cells, but produce haploid gametes (eggs and sperm) by meiosis. A monoploid has only one set of chromosomes, and the term is usually only applied to cells or organisms that are normally diploid. Male bees and other Hymenoptera, for example, are monoploid. Unlike animals, plants and multicellular algae have life cycles with two alternating multicellular generations. The gametophyte generation is haploid, and produces gametes by mitosis, the sporophyte generation is diploid and produces spores by meiosis.Polyploidy refers to a numerical change in a whole set of chromosomes. Organisms in which a particular chromosome, or chromosome segment, is under- or overrepresented are said to be aneuploid (from the Greek words meaning ""not"", ""good"", and ""fold""). Therefore the distinction between aneuploidy and polyploidy is that aneuploidy refers to a numerical change in part of the chromosome set, whereas polyploidy refers to a numerical change in the whole set of chromosomes.Polyploidy may occur due to abnormal cell division, either during mitosis, or commonly during metaphase I in meiosis.Polyploidy occurs in some animals, such as goldfish, salmon, and salamanders, but is especially common among ferns and flowering plants (see Hibiscus rosa-sinensis), including both wild and cultivated species. Wheat, for example, after millennia of hybridization and modification by humans, has strains that are diploid (two sets of chromosomes), tetraploid (four sets of chromosomes) with the common name of durum or macaroni wheat, and hexaploid (six sets of chromosomes) with the common name of bread wheat. Many agriculturally important plants of the genus Brassica are also tetraploids.Polyploidy can be induced in plants and cell cultures by some chemicals: the best known is colchicine, which can result in chromosome doubling, though its use may have other less obvious consequences as well. Oryzalin will also double the existing chromosome content.
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