Genetic balancers
... generated deficiencies on linkage group (LG) III that were lethal as homozygotes, Greenwald, I.S., and Horvitz, H.R. (1980) kept them as heterozygotes over an unc-93 dpy-17 chromosome. These animals were Unc-93 in phenotype because the deficiencies deleted unc-93, and they segregated Unc-93, Unc-93 ...
... generated deficiencies on linkage group (LG) III that were lethal as homozygotes, Greenwald, I.S., and Horvitz, H.R. (1980) kept them as heterozygotes over an unc-93 dpy-17 chromosome. These animals were Unc-93 in phenotype because the deficiencies deleted unc-93, and they segregated Unc-93, Unc-93 ...
Chapter_004 - IHMC Public Cmaps (2)
... Site on the long arm of the X chromosome Associated with mental retardation; second in occurrence to Down syndrome Higher incidence in males because they have only ...
... Site on the long arm of the X chromosome Associated with mental retardation; second in occurrence to Down syndrome Higher incidence in males because they have only ...
Human chromosomal bands: nested structure
... and to estimate how often each of those rules is used (see Table S3), but not for mapping or calculating length statistics, which are both done at the 850-band level. ...
... and to estimate how often each of those rules is used (see Table S3), but not for mapping or calculating length statistics, which are both done at the 850-band level. ...
Neurospora tetrasperma crosses heterozygous for hybrid
... of ‘first-cousin’ nuclei can become homoallelic for markers that underwent first-division segregation and heteroallelic for markers that underwent second-division segregation, whereas ascospores that receive a pair of ‘second-cousin’ nuclei can become homoallelic for markers that underwent second-di ...
... of ‘first-cousin’ nuclei can become homoallelic for markers that underwent first-division segregation and heteroallelic for markers that underwent second-division segregation, whereas ascospores that receive a pair of ‘second-cousin’ nuclei can become homoallelic for markers that underwent second-di ...
Regulation of meiotic progression by the meiosis
... Expression of the mek1+ gene was monitored by northern blot analysis during a pat1-driven synchronous meiosis (Fig. 2AC). Consistent with the results shown above, no expression of mek1+ is detected in vegetatively growing cells; its expression is induced at the same time as the onset of premeiotic S ...
... Expression of the mek1+ gene was monitored by northern blot analysis during a pat1-driven synchronous meiosis (Fig. 2AC). Consistent with the results shown above, no expression of mek1+ is detected in vegetatively growing cells; its expression is induced at the same time as the onset of premeiotic S ...
Analysis of CAG and CCG repeats in Huntingtin gene
... Analysis of the CAG repeat locus among 28 unrelated clinically diagnosed HD patients from the eastern part of India showed that the range of expansion of CAG repeats was between 41 and 56 in the huntingtin gene. The smallest size of the CAG repeat which causes HD is not defined precisely. In Western ...
... Analysis of the CAG repeat locus among 28 unrelated clinically diagnosed HD patients from the eastern part of India showed that the range of expansion of CAG repeats was between 41 and 56 in the huntingtin gene. The smallest size of the CAG repeat which causes HD is not defined precisely. In Western ...
Mendelian genetics
... Mendelian Genetics • We can determine an organism’s physical traits (characteristics) by examining its chromosomes. • Chromosomes are made up of a series of genes, sequences that code for proteins. • In the mid-1800s, Gregor Mendel experimented with pea plants. He discovered that he could predict w ...
... Mendelian Genetics • We can determine an organism’s physical traits (characteristics) by examining its chromosomes. • Chromosomes are made up of a series of genes, sequences that code for proteins. • In the mid-1800s, Gregor Mendel experimented with pea plants. He discovered that he could predict w ...
genetic variability, twin hybrids and constant hybrids, in a case of
... several years ago by DEXTER(1914).His extensive and exemplary investigations have, besides confirming points mentioned above, brought to light a number of further facts which have an important bearing on the problem. H e has found, firstly, that the character is markedly affected by various environm ...
... several years ago by DEXTER(1914).His extensive and exemplary investigations have, besides confirming points mentioned above, brought to light a number of further facts which have an important bearing on the problem. H e has found, firstly, that the character is markedly affected by various environm ...
The-NOS-problem
... First they generated a 20kb deletion of the NOS locus, which also included 5 flanking genes. This was called Df(2L)69F. In this review I’ll write it as Df(69F) as Pat did in lecture. Second they went through a screen for NOS point mutants, and they utilized Df(69F) to screen for lethality. FIGURE 1 ...
... First they generated a 20kb deletion of the NOS locus, which also included 5 flanking genes. This was called Df(2L)69F. In this review I’ll write it as Df(69F) as Pat did in lecture. Second they went through a screen for NOS point mutants, and they utilized Df(69F) to screen for lethality. FIGURE 1 ...
Effete, a Drosophila chromatin-associated ubiquitin
... DNA replication and shield chromosome ends from inappropriate DNA repair, which might result in end-to-end fusion (Palm and De Lange 2008; Jain and Cooper 2010; Raffa et al. 2011). In most organisms, telomeres terminate with tandemly repeated of G-rich sequences, which are added to chromosome ends b ...
... DNA replication and shield chromosome ends from inappropriate DNA repair, which might result in end-to-end fusion (Palm and De Lange 2008; Jain and Cooper 2010; Raffa et al. 2011). In most organisms, telomeres terminate with tandemly repeated of G-rich sequences, which are added to chromosome ends b ...
WING VEIN DEVELOPMENT IN CROSSVEINLESS-LIKE
... becomes enhanced by the increasing density of cells over the former. The progress of wing vein development with age: As described by WADDINGTON (1940) , the pupal wing begins with the end of expansion of the prepupal wing into a bloated sac. In the pupa this sac contracts into a flat blade, and the ...
... becomes enhanced by the increasing density of cells over the former. The progress of wing vein development with age: As described by WADDINGTON (1940) , the pupal wing begins with the end of expansion of the prepupal wing into a bloated sac. In the pupa this sac contracts into a flat blade, and the ...
get Assignment File
... a. Oak trees get taller as they grow. b. Hydrangea flower color varies with soil pH. c. Dandelion plants are self pollinating. d. Pinion trees bear cones every other year. ...
... a. Oak trees get taller as they grow. b. Hydrangea flower color varies with soil pH. c. Dandelion plants are self pollinating. d. Pinion trees bear cones every other year. ...
Complex inheritance of larval adaptation in Plutella
... of cultivated cruciferous vegetables in tropical and semitropical regions worldwide. However, in 1999 a population in the Kenyan Rift Valley was reported to feed on sugar snap pea (Pisum sativum L. var. macrocarpon, cultivar Oregon Sugar Pod (Fabaceae)) (Löhr, 2001; Löhr and Gathu, 2002). This sur ...
... of cultivated cruciferous vegetables in tropical and semitropical regions worldwide. However, in 1999 a population in the Kenyan Rift Valley was reported to feed on sugar snap pea (Pisum sativum L. var. macrocarpon, cultivar Oregon Sugar Pod (Fabaceae)) (Löhr, 2001; Löhr and Gathu, 2002). This sur ...
Synapsis-Mediated Fusion of Free DNA Ends Forms Inverted Dimer Plasmids in Yeast.
... the plasmid do not share homology with the yeast genome, circular inverted (head-to-head) dimer plasmids are theprincipal product of repair. By measurements of the DNA concentration dependence of transformation with alinearized plasmid, and by transformation with mixtures of genetically marked plasm ...
... the plasmid do not share homology with the yeast genome, circular inverted (head-to-head) dimer plasmids are theprincipal product of repair. By measurements of the DNA concentration dependence of transformation with alinearized plasmid, and by transformation with mixtures of genetically marked plasm ...
Identification of Functional Domains in the Cohesin Loader Subunit
... identify key regions in Scc4 that contribute to the interaction. In yeast, cohesin loading is regulated by a cell cycle-dependent proteolytic cleavage of Scc2. The protein is cleaved after loading in G1/S, and the cleaved product is unable to interact with Scc4 (Woodman et al. 2014). Biochemical ana ...
... identify key regions in Scc4 that contribute to the interaction. In yeast, cohesin loading is regulated by a cell cycle-dependent proteolytic cleavage of Scc2. The protein is cleaved after loading in G1/S, and the cleaved product is unable to interact with Scc4 (Woodman et al. 2014). Biochemical ana ...
Albinism Project - shsbiogeneticdisorders
... normal skin and hair color, although it is typically lighter than either parent. Many even have a normal eye appearance. Also, ocular albinism is generally sex-linked, therefore ...
... normal skin and hair color, although it is typically lighter than either parent. Many even have a normal eye appearance. Also, ocular albinism is generally sex-linked, therefore ...
Analysis of clones carrying repeated DNA sequences in two YAC
... EW (Ward and Jen, 1990) and Yup (Ecker, 1990) libraries. These are all derived from the Columbia ecotype. The average insert size in the EG and the EW libraries is 160 kb and the libraries represent three to four genome equivalents each, while the Yup library contains YACs with an average insert siz ...
... EW (Ward and Jen, 1990) and Yup (Ecker, 1990) libraries. These are all derived from the Columbia ecotype. The average insert size in the EG and the EW libraries is 160 kb and the libraries represent three to four genome equivalents each, while the Yup library contains YACs with an average insert siz ...
Instruction Manual for “ChromoPainter: a copying model for
... ChromoPainter is a program to explore admixture in the Single-NucleotidePolymorphism (SNP) data of haplotypes sampled from multiple populations. In particular, ChromoPainter takes as input: (1) the SNP data for a set of admixed “recipient” chromosomes, (2) the SNP data for a set of “donor” chromosom ...
... ChromoPainter is a program to explore admixture in the Single-NucleotidePolymorphism (SNP) data of haplotypes sampled from multiple populations. In particular, ChromoPainter takes as input: (1) the SNP data for a set of admixed “recipient” chromosomes, (2) the SNP data for a set of “donor” chromosom ...
CCA Summer 2004 Newsletter - Children`s Craniofacial Association
... (spontaneous gene mutation), and 70 percent of people with CCD have an affected parent. The condition is highly variable from one affected person to another. A brief review of chromosomes and genes may be helpful at this point. Genes are the basic units of heredity, and they are present in almost ev ...
... (spontaneous gene mutation), and 70 percent of people with CCD have an affected parent. The condition is highly variable from one affected person to another. A brief review of chromosomes and genes may be helpful at this point. Genes are the basic units of heredity, and they are present in almost ev ...
Polyploidy
... – the probability of having a second Down Syndrome child is usually similar to the population at large, ...
... – the probability of having a second Down Syndrome child is usually similar to the population at large, ...
13 MODIFIED TRUE/FALSE 1
... LOC: LS-R-01 TOP: The Function of the Nucleus within the Cell KEY: DNA | molecule | nitrogen | base 24. ANS: B PTS: 1 DIF: Average OBJ: Section LOC: LS-R-01 TOP: The Function of the Nucleus within the Cell KEY: genetic | code | bases | DNA | molecule 25. ANS: B PTS: 1 DIF: Average OBJ: Section LOC: ...
... LOC: LS-R-01 TOP: The Function of the Nucleus within the Cell KEY: DNA | molecule | nitrogen | base 24. ANS: B PTS: 1 DIF: Average OBJ: Section LOC: LS-R-01 TOP: The Function of the Nucleus within the Cell KEY: genetic | code | bases | DNA | molecule 25. ANS: B PTS: 1 DIF: Average OBJ: Section LOC: ...
Good quality blastocyst from non-/mono
... interesting for poor ovarian response women. However, there is no study giving an appropriate way to select the available mono- and non-pronuclear zygotes in clinic. In the present study, we found that the incidence rates of blastocysts with normal chromosomal composition were higher for non- and mo ...
... interesting for poor ovarian response women. However, there is no study giving an appropriate way to select the available mono- and non-pronuclear zygotes in clinic. In the present study, we found that the incidence rates of blastocysts with normal chromosomal composition were higher for non- and mo ...
Chromosome
A chromosome (chromo- + -some) is a packaged and organized structure containing most of the DNA of a living organism. It is not usually found on its own, but rather is complexed with many structural proteins called histones as well as associated transcription (copying of genetic sequences) factors and several other macromolecules. Two ""sister"" chromatids (half a chromosome) join together at a protein junction called a centromere. Chromosomes are normally visible under a light microscope only when the cell is undergoing mitosis. Even then, the full chromosome containing both joined sister chromatids becomes visible only during a sequence of mitosis known as metaphase (when chromosomes align together, attached to the mitotic spindle and prepare to divide). This DNA and its associated proteins and macromolecules is collectively known as chromatin, which is further packaged along with its associated molecules into a discrete structure called a nucleosome. Chromatin is present in most cells, with a few exceptions - erythrocytes for example. Occurring only in the nucleus of eukaryotic cells, chromatin composes the vast majority of all DNA, except for a small amount inherited maternally which is found in mitochondria. In prokaryotic cells, chromatin occurs free-floating in cytoplasm, as these cells lack organelles and a defined nucleus. The main information-carrying macromolecule is a single piece of coiled double-stranded DNA, containing many genes, regulatory elements and other noncoding DNA. The DNA-bound macromolecules are proteins, which serve to package the DNA and control its functions. Chromosomes vary widely between different organisms. Some species such as certain bacteria also contain plasmids or other extrachromosomal DNA. These are circular structures in the cytoplasm which contain cellular DNA and play a role in horizontal gene transfer.Compaction of the duplicated chromosomes during cell division (mitosis or meiosis) results either in a four-arm structure (pictured to the right) if the centromere is located in the middle of the chromosome or a two-arm structure if the centromere is located near one of the ends. Chromosomal recombination during meiosis and subsequent sexual reproduction plays a vital role in genetic diversity. If these structures are manipulated incorrectly, through processes known as chromosomal instability and translocation, the cell may undergo mitotic catastrophe and die, or it may unexpectedly evade apoptosis leading to the progression of cancer.In prokaryotes (see nucleoids) and viruses, the DNA is often densely packed and organized. In the case of archaea by homologs to eukaryotic histones, in the case of bacteria by histone-like proteins. Small circular genomes called plasmids are often found in bacteria and also in mitochondria and chloroplasts, reflecting their bacterial origins.