Quantitative trait loci associated with maximal exercise endurance in
... exercise endurance (HEE) and low exercise endurance (LEE), respectively (26). Ten female Balb/cJ mice were bred with nine male DBA/2J mice to produce BaD2 F1 mice. We chose the Balb/cJ mice as the maternal progenitor strain because earlier studies had suggested that exercise endurance was a maternal ...
... exercise endurance (HEE) and low exercise endurance (LEE), respectively (26). Ten female Balb/cJ mice were bred with nine male DBA/2J mice to produce BaD2 F1 mice. We chose the Balb/cJ mice as the maternal progenitor strain because earlier studies had suggested that exercise endurance was a maternal ...
HGSS2 Mendel
... genotype is defined as the two alleles that a person (or group of people) has at a locus. At the ABO locus, the genotypes are AA, AB, AO, BB, BO, and OO. (There is a tacit understanding that the heterozygotes AO and OA are the same genotype.) The word “genotype” may also be used as a vague designati ...
... genotype is defined as the two alleles that a person (or group of people) has at a locus. At the ABO locus, the genotypes are AA, AB, AO, BB, BO, and OO. (There is a tacit understanding that the heterozygotes AO and OA are the same genotype.) The word “genotype” may also be used as a vague designati ...
drosophila melanogaster.
... artificial selection experiment, selection for low recombination was not effective despite the demonstration of genetic variability in both directions in the base population; selection for high recombination was very effective. The patterns of recombination frequency changes in the 16A and 16B subli ...
... artificial selection experiment, selection for low recombination was not effective despite the demonstration of genetic variability in both directions in the base population; selection for high recombination was very effective. The patterns of recombination frequency changes in the 16A and 16B subli ...
Imprinting capacity of gamete lineages in C. elegans
... For reasons that are not well understood, a large fraction of transgene arrays in C. elegans exhibit mosaic expression: expression in some but not all of the cells where expression would be expected based on knowledge of the promoter used in the initial reporter construct (FIRE and MELLO 1995). Alth ...
... For reasons that are not well understood, a large fraction of transgene arrays in C. elegans exhibit mosaic expression: expression in some but not all of the cells where expression would be expected based on knowledge of the promoter used in the initial reporter construct (FIRE and MELLO 1995). Alth ...
Fine mapping of Noonan/cardio-facio cutaneous syndrome
... these individuals are so severely affected that they do not reproduce. It is possible that in some families CFC syndrome is not related to a gene on 12q24, but this has not yet been documented. However, present and previous data indicate that in several cases CFC syndrome is a severe expression of N ...
... these individuals are so severely affected that they do not reproduce. It is possible that in some families CFC syndrome is not related to a gene on 12q24, but this has not yet been documented. However, present and previous data indicate that in several cases CFC syndrome is a severe expression of N ...
Identification and Isolation of Dominant Susceptibility Loci for
... We have used rat models with striking similarities to human RA (15) in a system to examine the genetics of arthritis. Rat models that fulfil the criteria used for diagnosis of RA in humans include those with cartilage-restricted Ag-induced arthritis, such as collagen type II-induced arthritis (16), ...
... We have used rat models with striking similarities to human RA (15) in a system to examine the genetics of arthritis. Rat models that fulfil the criteria used for diagnosis of RA in humans include those with cartilage-restricted Ag-induced arthritis, such as collagen type II-induced arthritis (16), ...
EFFECT OF VARIOUS BIOMOLECULES FOR NORMAL FUNCTIONING OF HUMAN SPERM... FERTILIZATION: A REVIEW Research Article
... Zinc is acting as a cofactor for DNA-binding proteins that contain the zinc finger motif. Recent studies hypothesized that insufficient intake of Zn can impair antioxidant defence and may be an important risk factor in oxidant release, compromising the mechanism of DNA repair, and making the sperm c ...
... Zinc is acting as a cofactor for DNA-binding proteins that contain the zinc finger motif. Recent studies hypothesized that insufficient intake of Zn can impair antioxidant defence and may be an important risk factor in oxidant release, compromising the mechanism of DNA repair, and making the sperm c ...
genetics and cytogenetics
... grasp the fundamentals of heredIty in spite of limited biological training. However, I have also included some of the data that support these principles so that the student who wishes can ac~ quire an adequate background for further studies in heredity, and I have added a fairly extensive bibliograp ...
... grasp the fundamentals of heredIty in spite of limited biological training. However, I have also included some of the data that support these principles so that the student who wishes can ac~ quire an adequate background for further studies in heredity, and I have added a fairly extensive bibliograp ...
Leukaemia Section MLL amplification in leukemia Atlas of Genetics and Cytogenetics
... Drosophila trithorax (trx) protein, which is involved in the regulation of HOX gene expression. MLL plays an essential role in embryonic development, also as regulator of growth of hematopoietic precursors. ...
... Drosophila trithorax (trx) protein, which is involved in the regulation of HOX gene expression. MLL plays an essential role in embryonic development, also as regulator of growth of hematopoietic precursors. ...
Sequence requirements for function of the
... Large cloned fragments of the chorion gene loci can be re-introduced into the Drosophila genome via P elementmediated germline transformation, and these transgenic constructs can amplify with the correct tissue and temporal specificity (deCicco and Spradling, 1984). However, amplification is highly ...
... Large cloned fragments of the chorion gene loci can be re-introduced into the Drosophila genome via P elementmediated germline transformation, and these transgenic constructs can amplify with the correct tissue and temporal specificity (deCicco and Spradling, 1984). However, amplification is highly ...
Nosology of Deafness - American Academy of Audiology
... severe . In Waardenburg syndrome, an autosomal-dominant disorder, 50 percent of the offspring are affected but only 20 percent have deafness (Jones, 1988). Often in the same family, the expressivity differs substantially (e .g., see Treacher Collins Syndrome in this issue [Jahrsdoerfer and Jacobson, ...
... severe . In Waardenburg syndrome, an autosomal-dominant disorder, 50 percent of the offspring are affected but only 20 percent have deafness (Jones, 1988). Often in the same family, the expressivity differs substantially (e .g., see Treacher Collins Syndrome in this issue [Jahrsdoerfer and Jacobson, ...
15_chapter 5
... function of their topology and the choice of automata used. Evolutionary methods can be applied to the optimisation of the parameters, but their computational cost is prohibitive unless they operate on a compact representation. Earlier direct coding was used as it was simple. Grammar-based encoding ...
... function of their topology and the choice of automata used. Evolutionary methods can be applied to the optimisation of the parameters, but their computational cost is prohibitive unless they operate on a compact representation. Earlier direct coding was used as it was simple. Grammar-based encoding ...
Neurospora tetrasperma crosses heterozygous for hybrid
... the haploid parental mat A and mat a nuclei produces a diploid zygote nucleus that undergoes meiosis and a postmeiotic mitosis to generate 8 haploid progeny nuclei (4 mat A+ 4 mat a), that become partitioned into 4 initially binucleate (dikaryotic) ascospores, each ascospore receives a pair of non-s ...
... the haploid parental mat A and mat a nuclei produces a diploid zygote nucleus that undergoes meiosis and a postmeiotic mitosis to generate 8 haploid progeny nuclei (4 mat A+ 4 mat a), that become partitioned into 4 initially binucleate (dikaryotic) ascospores, each ascospore receives a pair of non-s ...
11. NEW DATA
... Only ten percent of all the offspring are found to have resulted from crossing over between vermilion and sable. It is known from certain experiments that in about forty percent of cases there is no crossing over whatever between the two X chromosomes. Of the sixty percent of cases in which crossing ...
... Only ten percent of all the offspring are found to have resulted from crossing over between vermilion and sable. It is known from certain experiments that in about forty percent of cases there is no crossing over whatever between the two X chromosomes. Of the sixty percent of cases in which crossing ...
Rather than test an unmapped gene successively for linkage to... groups, it is advantageous to test all linkage groups in... alcoy David Perkins
... temperature sensitive-1, yellow-1, and conidial separation-2 (which marks linkage group VII). All four are readily scored by eye. The strains grow on minimal medium. No transfer to test-media is necessary. Crosses heterozygous for alcoy .have proved useful in cytological studies of the synaptonemal ...
... temperature sensitive-1, yellow-1, and conidial separation-2 (which marks linkage group VII). All four are readily scored by eye. The strains grow on minimal medium. No transfer to test-media is necessary. Crosses heterozygous for alcoy .have proved useful in cytological studies of the synaptonemal ...
Selective Disruption of Aurora C Kinase Reveals Distinct Functions
... successful. Therefore, the meiotic function of AURKC is still not fully understood. Here, we describe an ATP-binding-pocketAURKC mutant, that when expressed in mouse oocytes specifically perturbs AURKC-CPC and not AURKB-CPC function. Using this mutant we show for the first time that AURKC has functi ...
... successful. Therefore, the meiotic function of AURKC is still not fully understood. Here, we describe an ATP-binding-pocketAURKC mutant, that when expressed in mouse oocytes specifically perturbs AURKC-CPC and not AURKB-CPC function. Using this mutant we show for the first time that AURKC has functi ...
Full Text
... select for moderate levels of PBC while selecting for Sr2. The genetic basis of the association between the durable rust resistance genes and the traits LTN and PBC is not completely understood. Despite the detection of many Quantitative Trait Loci (QTL) for LTN (Messmer et al., 2000; Schnurbusch et ...
... select for moderate levels of PBC while selecting for Sr2. The genetic basis of the association between the durable rust resistance genes and the traits LTN and PBC is not completely understood. Despite the detection of many Quantitative Trait Loci (QTL) for LTN (Messmer et al., 2000; Schnurbusch et ...
The genomic landscape of meiotic crossovers and gene
... Figure 1. Experimental design and summary of recombination events within 62 recombinants. (A) 13 complete tetrads were generated by crossing qrt1 in a Col background to qrt1 in a Ler background, and then using single pollen tetrads from the F1 hybrids to fertilize a Cvi male sterile pollen receptor. ...
... Figure 1. Experimental design and summary of recombination events within 62 recombinants. (A) 13 complete tetrads were generated by crossing qrt1 in a Col background to qrt1 in a Ler background, and then using single pollen tetrads from the F1 hybrids to fertilize a Cvi male sterile pollen receptor. ...
Alu - Environmental
... • Alu elements are only found in the primate branch • Each Alu insertion is a unique event and is inherited from each parent • Most occurred millions of years ago and are often on both pairs of chromosomes • There are Alu elements that have occurred since humans branched from other primates • This g ...
... • Alu elements are only found in the primate branch • Each Alu insertion is a unique event and is inherited from each parent • Most occurred millions of years ago and are often on both pairs of chromosomes • There are Alu elements that have occurred since humans branched from other primates • This g ...
Using Genetic Algorithms with Asexual Transposition
... transposition and one point crossover, two point and uniform crossover, for the Schwefel's function. The solutions obtained when using asexual transposition refer to populations size of 50 individuals, since that, with 100 and 200 strings, the results were always much better. After these detailed an ...
... transposition and one point crossover, two point and uniform crossover, for the Schwefel's function. The solutions obtained when using asexual transposition refer to populations size of 50 individuals, since that, with 100 and 200 strings, the results were always much better. After these detailed an ...
Novel familial cases of ICCA (infantile convulsions with paroxysmal
... increased in frequency and occurred almost daily. These were precipitated by unanticipated sudden movement, with his right arm stuck in a dystonic posture that lasted for a few seconds. His mother (II.4) also had similar symptoms starting at around six to seven years of age. She described her lower ...
... increased in frequency and occurred almost daily. These were precipitated by unanticipated sudden movement, with his right arm stuck in a dystonic posture that lasted for a few seconds. His mother (II.4) also had similar symptoms starting at around six to seven years of age. She described her lower ...
Arabidopsis Cell Division Cycle 20.1 Is Required for Normal Meiotic
... Aurora kinase, providing evidence that CDC20.1 regulates Aurora localization for meiotic chromosome segregation. Further evidence that CDC20.1 and Aurora are functionally related was provided by meiosis-specific knockdown of At-Aurora1 expression, resulting in meiotic chromosome segregation defects s ...
... Aurora kinase, providing evidence that CDC20.1 regulates Aurora localization for meiotic chromosome segregation. Further evidence that CDC20.1 and Aurora are functionally related was provided by meiosis-specific knockdown of At-Aurora1 expression, resulting in meiotic chromosome segregation defects s ...
genetics - Krishikosh
... Dr. Altenburg was born in Jersey City in 1888. He received all his academic degrees - the A. B. in 1911, A. M. in 1912, and Ph. D. in 1916 - from Columbia Uinversity, where he was a student of T. H. Margan.. It was there that he and H. J. Muller met and became friends and research collaborators, and ...
... Dr. Altenburg was born in Jersey City in 1888. He received all his academic degrees - the A. B. in 1911, A. M. in 1912, and Ph. D. in 1916 - from Columbia Uinversity, where he was a student of T. H. Margan.. It was there that he and H. J. Muller met and became friends and research collaborators, and ...
Figure 15.6 Nonreplicative transposition allows a transposon to
... released by nicking. This inserts the transposon into the target DNA, flanked by the direct repeats of the target, and the donor is left with a double-strand break. ...
... released by nicking. This inserts the transposon into the target DNA, flanked by the direct repeats of the target, and the donor is left with a double-strand break. ...
15.13 Spm elements influence gene expression
... released by nicking. This inserts the transposon into the target DNA, flanked by the direct repeats of the target, and the donor is left with a double-strand break. ...
... released by nicking. This inserts the transposon into the target DNA, flanked by the direct repeats of the target, and the donor is left with a double-strand break. ...