Forche et al. 2008 PLoS Biology
... precisely halve the DNA content in the cell, often for the formation of haploid gametes from diploid precursor cells. This specialized form of cell division involves one round of DNA replication followed by two successive rounds of DNA division. Each round of DNA division is unique. During the first ...
... precisely halve the DNA content in the cell, often for the formation of haploid gametes from diploid precursor cells. This specialized form of cell division involves one round of DNA replication followed by two successive rounds of DNA division. Each round of DNA division is unique. During the first ...
Nematode genome evolution
... an 11-gene region sequenced from P. pacificus chromosome III, 10/11 genes had orthologs on C. elegans chromosome III (Lee et al., 2003). This led Lee et al. to suggest that P. pacificus chromosome III and C. elegans chromosome III shared a common ancestor. If this is true, there must have been a lot ...
... an 11-gene region sequenced from P. pacificus chromosome III, 10/11 genes had orthologs on C. elegans chromosome III (Lee et al., 2003). This led Lee et al. to suggest that P. pacificus chromosome III and C. elegans chromosome III shared a common ancestor. If this is true, there must have been a lot ...
The Parasexual Cycle in Candida albicans Provides an
... precisely halve the DNA content in the cell, often for the formation of haploid gametes from diploid precursor cells. This specialized form of cell division involves one round of DNA replication followed by two successive rounds of DNA division. Each round of DNA division is unique. During the first ...
... precisely halve the DNA content in the cell, often for the formation of haploid gametes from diploid precursor cells. This specialized form of cell division involves one round of DNA replication followed by two successive rounds of DNA division. Each round of DNA division is unique. During the first ...
PPT File
... produced by meiosis, rather than mitosis • Meiosis results in one set of chromosomes in each gamete • Fertilization and meiosis alternate in sexual life cycles to maintain chromosome number Copyright © 2008 Pearson Education Inc., publishing as Pearson Benjamin Cummings ...
... produced by meiosis, rather than mitosis • Meiosis results in one set of chromosomes in each gamete • Fertilization and meiosis alternate in sexual life cycles to maintain chromosome number Copyright © 2008 Pearson Education Inc., publishing as Pearson Benjamin Cummings ...
Genome-Wide Scan of Obesity in the Old Order Amish*
... same BMI. BMI-adjusted leptin levels were highly correlated with both percent fat (r ⫽ 0.60) and the original (i.e. unadjusted) leptin concentrations (r ⫽ 0.76), suggesting a potential link between BMI-adjusted leptin levels and obesity. The heritabilities for BMI, waist circumference, percent fat, ...
... same BMI. BMI-adjusted leptin levels were highly correlated with both percent fat (r ⫽ 0.60) and the original (i.e. unadjusted) leptin concentrations (r ⫽ 0.76), suggesting a potential link between BMI-adjusted leptin levels and obesity. The heritabilities for BMI, waist circumference, percent fat, ...
Quantitative trait loci affecting amylose, amylopectin and starch
... that favourable effects over the 2 years are well balanced between Io and F-2, eleven vs. thirteen, respectively, when pooling all traits and both methods (table III). However, large differences appeared when looking at trait by trait. In 1995 for AP, most of the beneficial alleles were from F-2 (5/ ...
... that favourable effects over the 2 years are well balanced between Io and F-2, eleven vs. thirteen, respectively, when pooling all traits and both methods (table III). However, large differences appeared when looking at trait by trait. In 1995 for AP, most of the beneficial alleles were from F-2 (5/ ...
Research in Biology
... and finally the DNA sequence requirements on the X chromosome. At the start of my post-doc it was of great interest to know how these “three distinct parts” evolved; whether they were all conserved, all diverged, or a combination of the two. This was a relatively unexplored aspect of nematode dosage ...
... and finally the DNA sequence requirements on the X chromosome. At the start of my post-doc it was of great interest to know how these “three distinct parts” evolved; whether they were all conserved, all diverged, or a combination of the two. This was a relatively unexplored aspect of nematode dosage ...
A Feeling for the Organism — Life and Work of Barbara McClintock
... existence. We have the circumstantial evidence of thousands of years of Anastasia's ancestors, many of whom lived well past their hundredth birthday, and the scientific evidence of over fifty years of Barbara McClintock's life(1). There is another aspect of Barbara McClintock's life and work which a ...
... existence. We have the circumstantial evidence of thousands of years of Anastasia's ancestors, many of whom lived well past their hundredth birthday, and the scientific evidence of over fifty years of Barbara McClintock's life(1). There is another aspect of Barbara McClintock's life and work which a ...
Chpt8_RecombineDNA.doc
... from two parental DNA molecules or different segments of the same DNA molecule; this will be the topic of this chapter. Transposition is a highly specialized form of recombination in which a segment of DNA moves from one location to another, either on the same chromosome or a different chromosome; t ...
... from two parental DNA molecules or different segments of the same DNA molecule; this will be the topic of this chapter. Transposition is a highly specialized form of recombination in which a segment of DNA moves from one location to another, either on the same chromosome or a different chromosome; t ...
X-Chromosome dosage compensation
... The discovery of sex-specific lethal mutations that preferentially killed XX hermaphrodites was pivotal for the identification of dosage compensation genes (Hodgkin, 1983; Plenefisch et al., 1989). Mutations in eight genes-sdc-1, sdc-2, sdc-3, dpy-21, dpy-26, dpy-27, dpy-28, and dpy-30 reduced the v ...
... The discovery of sex-specific lethal mutations that preferentially killed XX hermaphrodites was pivotal for the identification of dosage compensation genes (Hodgkin, 1983; Plenefisch et al., 1989). Mutations in eight genes-sdc-1, sdc-2, sdc-3, dpy-21, dpy-26, dpy-27, dpy-28, and dpy-30 reduced the v ...
What is the cause of autism?
... developmental disability group. 1998-2002 there was a 96.69% increase in reported cases. ...
... developmental disability group. 1998-2002 there was a 96.69% increase in reported cases. ...
Adaptive evolution drives divergence of a hybrid inviability gene
... incompatible with alleles at interacting loci from another species. However, almost nothing is known about the genes involved in such hybrid incompatibilities or the evolutionary forces that drive their divergence. Here we identify a gene that causes epistatic inviability in hybrids between two frui ...
... incompatible with alleles at interacting loci from another species. However, almost nothing is known about the genes involved in such hybrid incompatibilities or the evolutionary forces that drive their divergence. Here we identify a gene that causes epistatic inviability in hybrids between two frui ...
A Novel Compact Genetic Algorithm using Offspring Survival
... cGA using os-ES. Section IV shows the simulation results on well-known benchmark functions. Section V presents the summary of the results. ...
... cGA using os-ES. Section IV shows the simulation results on well-known benchmark functions. Section V presents the summary of the results. ...
Patterns of Inheritance
... alleles is not always the case; some alleles are codominant, and sometimes dominance is incomplete.) Using his understanding of dominant and recessive traits, Mendel tested whether a recessive trait could be lost altogether in a pea lineage or whether it would resurface in a later generation. By cro ...
... alleles is not always the case; some alleles are codominant, and sometimes dominance is incomplete.) Using his understanding of dominant and recessive traits, Mendel tested whether a recessive trait could be lost altogether in a pea lineage or whether it would resurface in a later generation. By cro ...
Kinetic proofreading of gene activation by chromatin remodeling
... the previous section that the main contribution in discrimination is due to the presence of the remodeling step, while changes in mere equilibrium binding matter considerably less. Therefore, the experimental observation can easily be interpreted by noting that the changes in binding energy due to t ...
... the previous section that the main contribution in discrimination is due to the presence of the remodeling step, while changes in mere equilibrium binding matter considerably less. Therefore, the experimental observation can easily be interpreted by noting that the changes in binding energy due to t ...
Mitotic recombination counteracts the benefits of
... varying parameters on the waiting times. For example, we graphically explored the sensitivity of the waiting time to changes in population size and dominance coefficients across a range of parameters: N varied from 104 to 108, r varied from 10K10 to 10K4, h varied from 0.01 to 0.99, s varied from 0. ...
... varying parameters on the waiting times. For example, we graphically explored the sensitivity of the waiting time to changes in population size and dominance coefficients across a range of parameters: N varied from 104 to 108, r varied from 10K10 to 10K4, h varied from 0.01 to 0.99, s varied from 0. ...
Scientist finds the gene that determines major sensitivity to bitter taste
... world. Those millions of Europeans, Asians, and individuals from other populations around the world who are non-tasters descended from a common ancestor who emerged from Africa far back in prehistory. Human DNA sequences are overwhelmingly similar, with some small, but sometimes important difference ...
... world. Those millions of Europeans, Asians, and individuals from other populations around the world who are non-tasters descended from a common ancestor who emerged from Africa far back in prehistory. Human DNA sequences are overwhelmingly similar, with some small, but sometimes important difference ...
Kinds and Rates of Human Heritable Mutations
... of sentinel phenotypes. The most important one results from the choice of phenotypes studied: phenotypes that occur in the population most often are the ones most likely to be recorded. Phenotypes that are so severe as to cause prenatal death, or so mild as to be indistinguishable from the normal va ...
... of sentinel phenotypes. The most important one results from the choice of phenotypes studied: phenotypes that occur in the population most often are the ones most likely to be recorded. Phenotypes that are so severe as to cause prenatal death, or so mild as to be indistinguishable from the normal va ...
... the COGA sample has few Asian families but rather consists primarily of non-Hispanic White and African American families. This linkage result on chromosome 4 suggests that the protective effects of ADH are not limited to the Asian population. We report the results of additional genotyping performed ...
17. Prof. K. P. Bhatia: Paroxysmal Movement Disorders
... An autosomal dominant pattern of inheritance has been noted in all reported families with typical PNKD.4,18-21 A family with PDC with interictal myokymia22 and another with spasticity referred to as CSE (choreoathetosis/spasticity, episodic movement disorder) have been reported.23 Patients usually d ...
... An autosomal dominant pattern of inheritance has been noted in all reported families with typical PNKD.4,18-21 A family with PDC with interictal myokymia22 and another with spasticity referred to as CSE (choreoathetosis/spasticity, episodic movement disorder) have been reported.23 Patients usually d ...
Genome position and gene amplification | SpringerLink
... may be post-transcriptional, post-translational or involve alteration in expression of upstream genes. Tumor subtypes may also be distinguished by their propensity to amplify oncogenes, suggesting that the particular types of genomic instability present in a tumor are important determinants of how e ...
... may be post-transcriptional, post-translational or involve alteration in expression of upstream genes. Tumor subtypes may also be distinguished by their propensity to amplify oncogenes, suggesting that the particular types of genomic instability present in a tumor are important determinants of how e ...
The role of meiotic drive in hybrid male sterility
... or XO species, competition between the two chromosomes would be eliminated and no arms race would occur to increase the chance of hybrid incompatibilities (reviewed further in Coyne & Orr 2004). The remainder of this review will focus mainly on X chromosome male drive and its relevance to speciation ...
... or XO species, competition between the two chromosomes would be eliminated and no arms race would occur to increase the chance of hybrid incompatibilities (reviewed further in Coyne & Orr 2004). The remainder of this review will focus mainly on X chromosome male drive and its relevance to speciation ...
publication
... The Giemsa negative band q22 of human chromosome 7 is an area known to be gene-rich and prone to chromosomal breakage. Aberrations at 7q22 are commonly observed in myeloid leukemias and myelodysplastic syndromes, with critical deleted regions being mapped using fluorescent in situ hybridization (1–4 ...
... The Giemsa negative band q22 of human chromosome 7 is an area known to be gene-rich and prone to chromosomal breakage. Aberrations at 7q22 are commonly observed in myeloid leukemias and myelodysplastic syndromes, with critical deleted regions being mapped using fluorescent in situ hybridization (1–4 ...
oil palm haploid technology: screening for naturally
... chromosome number (n) or having a single set of chromosomes. Knowledge of the haploid number is useful in breeding and genetic studies. Haploids are used to produce double haploids (2n) where the chromosome number is doubled using chemicals. Chemicals such as colchicine or oryzalin interfere with tu ...
... chromosome number (n) or having a single set of chromosomes. Knowledge of the haploid number is useful in breeding and genetic studies. Haploids are used to produce double haploids (2n) where the chromosome number is doubled using chemicals. Chemicals such as colchicine or oryzalin interfere with tu ...
Detecting copy number variants and runs of homozygosity on a
... challenging. It is not possible to detect UPD using a All ROH have the potential to cause an autosomal traditional CGH array as there are no changes in recessive disease. However, it is the excessively CN, so a platform containing SNP probes must be long ROH that are likely to greatly increase the u ...
... challenging. It is not possible to detect UPD using a All ROH have the potential to cause an autosomal traditional CGH array as there are no changes in recessive disease. However, it is the excessively CN, so a platform containing SNP probes must be long ROH that are likely to greatly increase the u ...