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in cellular neuroscience
in cellular neuroscience

... the glia of the worm to those of animals possessing more complex nervous systems. For these comparisons to be accurate, it is important to keep in mind that the nervous system of the worm likely contains fewer cells and connections that are optimal for its ecological niche, and not because it did no ...
syg-2
syg-2

... Scanning EM; 150μm region centered on the vulva 1 WT L4; 1 L4 syg-1(ky652); 2 L4 syg-2(ky673); 1 L4 syg-2(ky671) ...
Cilia development, morphogenesis, and
Cilia development, morphogenesis, and

... "'G?#(*8J iltrastructure of C. elegans cilia. 2a. Cilia in the amphid sensillum exhibit a variety of morphologies. The rod-like channel cilia are found in XS`, XSG, XSH, XSI, XSh, XSK, XDF, and XDL neurons. XDF and XDL possess two cilia each, while the other cells possess a single cilium. These cili ...
Cell-Specific Transcriptional Profiling of Ciliated Sensory Neurons
Cell-Specific Transcriptional Profiling of Ciliated Sensory Neurons

... and cil-7 are required for response and vulva location behaviors, but not sex drive [20]. For the EVN-specific genes regulating mating behaviors, response and vulva location depended on EV biogenesis or cilia-EV interactions, whereas sex drive was independent. These results also suggest that polycys ...
Students labor on the Worm Farm
Students labor on the Worm Farm

... elegans – alive and well-fed for Miller’s experiments. Dalton is a molecular biology and computer science major while Maune is majoring in molecular biology and chemistry. The two women have held paid positions in the lab for about three years. Along with growing worm food, the two seniors are curre ...
Pseudocoelomates
Pseudocoelomates

... Nematode muscle cells are unique: they have “arms” that contact the nerve cord. In most species, nerve cells have processes that touch muscles. ...
Major Divisions of Life
Major Divisions of Life

... Nematode muscle cells are unique: they have “arms” that contact the nerve cord. In most species, nerve cells have processes that touch muscles. ...
Mather research with USC colleagues compares octopus
Mather research with USC colleagues compares octopus

... “Most  of  us  are  used  to  the  idea  that  we  move  around  with  muscles  attached  to  bones,   but  many  movement  systems  don't  do  that,”  says  Mather,  who  leaves  this  week  for  a   field  study  at  USC.  “Sy ...
Contents •
Contents •

... Regulation of Centromere Localization of the Drosophila Shugoshin MEI-S332 and Sister-Chromatid Cohesion in Meiosis Cristina Nogueira, Helena Kashevsky, Belinda Pinto, Astrid Clarke, and Terry L. Orr-Weaver Shugoshin (Sgo) proteins play an essential role in accurate chromosome segregation in mitosis ...
Evolution and analysis of minimal neural circuits for klinotaxis in
Evolution and analysis of minimal neural circuits for klinotaxis in

... Recently, Iino and colleagues have described a complementary strategy, called klinotaxis. This work combines neural network modeling and evolutionary algorithms to identify simple circuit motifs for klinotaxis. It then uses dynamical systems analysis to understand how they function. ...
A leading centre for innovation, expertise, and discovery
A leading centre for innovation, expertise, and discovery

... genes involved in the development and function of synapses. In the last few years, her lab has discovered novel “ion channel” proteins that affect the communication between neurons and neural circuits, and are also implicated in developmental defects. Her research team and colleagues have also ident ...
How do maggots and worms navigate temperature
How do maggots and worms navigate temperature

... limited research council funds on? This particular study carried out in the daVinci group, Harvard University uses nematode C. elegans organisms. The nematode C. elegans are ideal for the study as they comprise of just 302 neurons, they are optically transparent and about 1mm long therefore each neu ...
The beginning of connectomics: a commentary on White
The beginning of connectomics: a commentary on White

... worm’s connectome. Publications started with a description of the head sensory structures in 1975 [10], of the pharyngeal nervous system [11] and ventral nerve cord [8] in 1976 and of a partial reconstruction of the circuits in the male tail in 1980 [12]. (The male tail connectome was completed in t ...
Supplemental discussion of modifier gene function
Supplemental discussion of modifier gene function

... cash-1 encodes the C. elegans ortholog of mammalian striatin known as CKA in Drosophila [81]. Striatin contains calveolin-binding, calmodulin-binding, and WD-repeat domains that may couple endocytosis to signaling pathways and hormone receptors [82]. Striatin expression is highly enriched in the ner ...
S. Zuryn et al. 5 SI Supporting Methods Preparation of mutants: C
S. Zuryn et al. 5 SI Supporting Methods Preparation of mutants: C

... This strategy vastly increases the overall robustness of mutation identification by minimizing false-positive and falsenegative results caused by reference genome errors. We recommend backcrossing to the original strain that was subjected to mutagenesis. Doing so ensures that all mutant strains will ...
C. elegans Neurology Supplement - Bio-Rad
C. elegans Neurology Supplement - Bio-Rad

... intensity over long distances and to speed up signal transmission by serving as an insulator. C. elegans neurons do not transmit signals across large distances, since C. elegans grow to be only about 1 mm long, and thus do not have a need for myelin. The neuronal system is the most complex organ sys ...
So, do worms sleep?
So, do worms sleep?

... Despite much progress in our understanding of C. elegans locomotion and navigation, little is known about the regulation of the absence of movement. Yet behavioral quiescent states are universal to the animal world, with the most famous and mysterious of these being sleep. The roundworm C. elegans i ...
Hunting a robot controlled by an artificial brain
Hunting a robot controlled by an artificial brain

... For the demonstration we have the following requirements: a space of 4x4x3 meter is needed. The motion tracking system is mounted on poles around this area. For safety, we can guard the surroundings with curtains mounted on the poles, although the AR.Drone has its own safety mechanism. The ground ro ...
Research Proposal: Nivedita Chatterjee
Research Proposal: Nivedita Chatterjee

... glia-like cells. This work will also use existing mutant strains to study genes involved in neuron-glia interactions during nervous system development. So far, there exists little information as to how the activities of individual neurons might correlate with particular behavioral patterns. In colla ...
Postdoctoral Researcher /Research Associate Bio
Postdoctoral Researcher /Research Associate Bio

Slide 1
Slide 1

...  Male mating: mating hermaphrodites + males increases number of males up to 50%  Heat-shock: exposure of hermaphrodites to 30°C for several hours increases  Exposure to ethanol increases the number of males ...
Characterising nicotinic acetylcholine receptors in the plant parasitic
Characterising nicotinic acetylcholine receptors in the plant parasitic

... within a short time period while the environmental conditions are optimal. Therefore, locomotion is an essential component of its invasion strategy. It belongs to the phylum Nematoda, which also includes the free-living model genetic nematode C. elegans. We explored the idea that the neurobiological ...
Neural Network of C. elegans is a Small
Neural Network of C. elegans is a Small

... Masroor Hossain Wednesday, February 29th, 2012 Introduction to Complex Systems ...
Varsha Singh Indian Institute of Science, Bangalore, India
Varsha Singh Indian Institute of Science, Bangalore, India

... How does a bacterivore defend itself from pathogenic microbes? C. elegans lives in soil, close to dead or decaying matter which provides source of nutrition. A decaying piece of fruit may have both pathogenic bacteria and food bacteria making it essential for worms to pick and choose. One might imag ...
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Caenorhabditis elegans



Caenorhabditis elegans /ˌseɪnɵræbˈdɪtɪs ˈɛlɛɡænz/ is a free-living (not parasitic), transparent nematode (roundworm), about 1 mm in length, that lives in temperate soil environments. The name is a blend of Greek (caeno- - recent, rhabditis - rod-like) and Latin (elegans - elegant). In 1900, Maupas initially named it Rhabditides elegans, Osche placed it in the subgenus Caenorhabditis in 1952, and in 1955, Dougherty raised it to the status of genus.C. elegans is an unsegmented pseudocoelomate, and lacks a respiratory and a circulatory system. They possess gut granules which emit a brilliant blue fluorescence, a wave of which is seen at death in a 'death fluorescence'. The majority of these nematodes are female hermaphrodites. Males have specialised tails for mating that include spicules.In 1963, Sydney Brenner proposed research into C. elegans primarily in the area of neuronal development. In 1974, he began research into the molecular and developmental biology of C. elegans, which has since been extensively used as a model organism.C. elegans was the first multicellular organism to have its whole genome sequenced, and as of 2012, the only organism to have its connectome (neuronal ""wiring diagram"") completed.
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