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Enhancement of dissolution rate of poorly water
... by a simple blending with selected powder excipients referred to as the carrier and coating materials7–9. Various grades of cellulose, starch, lactose, and so on, may be used as the carriers, whereas very fine-particle-size silica powders may be used as the coating (or covering) materials10, 11. In ...
... by a simple blending with selected powder excipients referred to as the carrier and coating materials7–9. Various grades of cellulose, starch, lactose, and so on, may be used as the carriers, whereas very fine-particle-size silica powders may be used as the coating (or covering) materials10, 11. In ...
Pharmaceutical Dosage Forms
... • The drug in a particular dosage form is not commercially available on the market • The extraordinary low or high dose is needed (young children, elderly people, special situations – e.g., intoxications). In this case right dosage strength need not be readily commercially available for every patien ...
... • The drug in a particular dosage form is not commercially available on the market • The extraordinary low or high dose is needed (young children, elderly people, special situations – e.g., intoxications). In this case right dosage strength need not be readily commercially available for every patien ...
DRUG PROFILES Structural formula of Losartan
... ingredient preparations for the management of diarrhea, constipation, and obesity; it has also been used in a colon biodegradable pectin matrix with a pH-sensitive polymeric coating, which retards the onset of drug release, overcoming the problems of pectin solubility in the upper GI tract. Descript ...
... ingredient preparations for the management of diarrhea, constipation, and obesity; it has also been used in a colon biodegradable pectin matrix with a pH-sensitive polymeric coating, which retards the onset of drug release, overcoming the problems of pectin solubility in the upper GI tract. Descript ...
1.3.1.3 Package Leaflet
... pharmacist if you are not sure. Swallow the tablets with water, you can take them with or without food. You should take the last daily dose at the end of the afternoon. The recommended doses are: Starting dose: 10 mg 2 to 3 times daily. Maintenance dose: 40-80 mg daily divided in 2 to 3 doses. ...
... pharmacist if you are not sure. Swallow the tablets with water, you can take them with or without food. You should take the last daily dose at the end of the afternoon. The recommended doses are: Starting dose: 10 mg 2 to 3 times daily. Maintenance dose: 40-80 mg daily divided in 2 to 3 doses. ...
proper usage of drugs, chemicals and feed additives in food animals
... Shock may be observed following intravenous administration, especially where highly concentrated materials are involved. To minimize this occurrence, it is recommended that LIQUAMYCIN® LA-200 ® be administered slowly by this route. Shortly after injection, treated animals may have transient hemoglob ...
... Shock may be observed following intravenous administration, especially where highly concentrated materials are involved. To minimize this occurrence, it is recommended that LIQUAMYCIN® LA-200 ® be administered slowly by this route. Shortly after injection, treated animals may have transient hemoglob ...
Document Content Authoring and Hybrid Knowledge Bases
... fact that a certain pharmaceutical drug contains some molecule makes it dangerous for a certain patient condition) and (2) constraints about document organization (if a certain drug is dangerous for a certain condition, then a warning should be generated at a certain place in the document). A more p ...
... fact that a certain pharmaceutical drug contains some molecule makes it dangerous for a certain patient condition) and (2) constraints about document organization (if a certain drug is dangerous for a certain condition, then a warning should be generated at a certain place in the document). A more p ...
Public Assessment Report Scientific discussion Telhyd 40 mg/12.5
... Results remain within specification limits up to 24 months at long-term and intermediate conditions and 6 months accelerated conditions. The only change that was observed in photo stability studies was the appearance of ‘open’ tablets. The proposed shelf-life period of 24 months can be granted. No s ...
... Results remain within specification limits up to 24 months at long-term and intermediate conditions and 6 months accelerated conditions. The only change that was observed in photo stability studies was the appearance of ‘open’ tablets. The proposed shelf-life period of 24 months can be granted. No s ...
November 2014 PBAC Meeting
... The submission claimed that the oral suspension and tablets have been shown to be bioequivalent for pharmacokinetic parameter of area under curve (AUC), and so can be expected to behave similarly in therapeutic use. The submission further noted that the liquid formulation is absorbed more rapidly th ...
... The submission claimed that the oral suspension and tablets have been shown to be bioequivalent for pharmacokinetic parameter of area under curve (AUC), and so can be expected to behave similarly in therapeutic use. The submission further noted that the liquid formulation is absorbed more rapidly th ...
FORMULATION, CHARACTERIZATION AND COMPARATIVE IN VITRO IN VIVO EVALUATION
... important in the pharmaceutical manufacturing industry. SR preparations are sophisticated products which have become so expensive that they are beyond the reach of many people. This is evident not only in Third World Countries but also in affluent societies1. Matrix systems still appear as one of th ...
... important in the pharmaceutical manufacturing industry. SR preparations are sophisticated products which have become so expensive that they are beyond the reach of many people. This is evident not only in Third World Countries but also in affluent societies1. Matrix systems still appear as one of th ...
Rx only for women younger than age 17
... ------------------------------------INDICATIONS AND USAGE-----------------------------------Next Choice One DoseTM is a progestin-only emergency contraceptive indicated for prevention of pregnancy following unprotected intercourse or a known or suspected contraceptive failure. Next Choice One DoseTM ...
... ------------------------------------INDICATIONS AND USAGE-----------------------------------Next Choice One DoseTM is a progestin-only emergency contraceptive indicated for prevention of pregnancy following unprotected intercourse or a known or suspected contraceptive failure. Next Choice One DoseTM ...
View PDF - e-Science Central
... predominant issue for a selected kind of polymers, in most cases drug unharnesses mechanics could be results of a mix of those 2 mechanisms. The presence of water decreases the glassy-rubbery temperature (for HPMC from 184°C to below 37°C), giving rise to transformation of glassy chemical compound t ...
... predominant issue for a selected kind of polymers, in most cases drug unharnesses mechanics could be results of a mix of those 2 mechanisms. The presence of water decreases the glassy-rubbery temperature (for HPMC from 184°C to below 37°C), giving rise to transformation of glassy chemical compound t ...
Respiratory Drug Agents
... intubated, and assisted ventilation was administered. The patient came out of the arrest but then returned to his preadmission state of wheezing and respiratory failure. Labs: CBC: leukocytosis, metabolic acidosis, hypoxemia, and airway obstruction. ...
... intubated, and assisted ventilation was administered. The patient came out of the arrest but then returned to his preadmission state of wheezing and respiratory failure. Labs: CBC: leukocytosis, metabolic acidosis, hypoxemia, and airway obstruction. ...
Neofloxin Prescribing Information
... without meals. The preferred time of dosing is two hours after a meal. Patients should also be advised to drink fluids liberally and not take antacids containing magnesium or aluminium concomitantly or within two hours after dosing. Ciprofloxacin may cause dizziness and lightheadedness, therefore pa ...
... without meals. The preferred time of dosing is two hours after a meal. Patients should also be advised to drink fluids liberally and not take antacids containing magnesium or aluminium concomitantly or within two hours after dosing. Ciprofloxacin may cause dizziness and lightheadedness, therefore pa ...
Quality assessment of samples of generic and similar aspirin tablets
... The interchangeability between a generic and the respective reference drug is based on the concept of therapeutic equivalence between them, usually provided by evidence of pharmaceutical equivalence, bioequivalence, Good Manufacturing Practices (GMP), and quality control. This study aimed to evaluat ...
... The interchangeability between a generic and the respective reference drug is based on the concept of therapeutic equivalence between them, usually provided by evidence of pharmaceutical equivalence, bioequivalence, Good Manufacturing Practices (GMP), and quality control. This study aimed to evaluat ...
PDR Physicians` Desk Reference PROOF
... CAN CAUSE INJURY. • Squeeze bottle until nearly all liquid is gone. It is not necessary to empty the bottle completely, as it contains more liquid than needed. A small amount of liquid will remain in the bottle after squeezing. • Remove Comfortip® from rectum and discard bottle. • Maintain position ...
... CAN CAUSE INJURY. • Squeeze bottle until nearly all liquid is gone. It is not necessary to empty the bottle completely, as it contains more liquid than needed. A small amount of liquid will remain in the bottle after squeezing. • Remove Comfortip® from rectum and discard bottle. • Maintain position ...
DESIGN AND DEVELOPMENT OF MUCOADHESIVE BUCCAL DELIVERY FOR PANTOPRAZOLE
... Buccal drug delivery is an alternative route for the oral administration of drugs which undergo degradation in the gastrointestinal track or hepatic first pass metabolism. Buccal drug delivery offers a safer mode of drug delivery system and the dosage form can be removed in case of toxicity. Buccal ...
... Buccal drug delivery is an alternative route for the oral administration of drugs which undergo degradation in the gastrointestinal track or hepatic first pass metabolism. Buccal drug delivery offers a safer mode of drug delivery system and the dosage form can be removed in case of toxicity. Buccal ...
Development of solid self-emulsifying drug delivery systems: preparation techniques and dosage forms
... solubility in water, which leads to poor bioavailability, high intrasubject/intersubject variability and lack of dose proportionality. Furthermore, oral delivery of numerous drugs is hindered owing to their high hydrophobicity [1,2]. Therefore, producing suitable formulations is very important to im ...
... solubility in water, which leads to poor bioavailability, high intrasubject/intersubject variability and lack of dose proportionality. Furthermore, oral delivery of numerous drugs is hindered owing to their high hydrophobicity [1,2]. Therefore, producing suitable formulations is very important to im ...
Evaluation of Quality Control Parameters of Two Brands of
... subjected to physical parameter tests such as weight variation, hardness, thickness, friability and disintegration. The brands passed the tests as no tablets cross the ±7.5% weight variation. Average thickness of the Seduxen® was 0.252cm with 0% variation and average thickness of Sedil® was 3.155cm ...
... subjected to physical parameter tests such as weight variation, hardness, thickness, friability and disintegration. The brands passed the tests as no tablets cross the ±7.5% weight variation. Average thickness of the Seduxen® was 0.252cm with 0% variation and average thickness of Sedil® was 3.155cm ...
selegiline (se-le-ji-leen) - DavisPlus
... 5 wk prior to selegiline, venlafaxine should be discontinued 7 days before selegiline, other agents should be discontinued 2 wk before selegiline). Selegiline should be discontinued 2 wk before SSRIs are initiated. Concurrent use with tricyclic antidepressants may result in asystole, diaphoresis, hy ...
... 5 wk prior to selegiline, venlafaxine should be discontinued 7 days before selegiline, other agents should be discontinued 2 wk before selegiline). Selegiline should be discontinued 2 wk before SSRIs are initiated. Concurrent use with tricyclic antidepressants may result in asystole, diaphoresis, hy ...
FORMULATION AND IN VITRO EVALUATION OF SUSTAINED RELEASE FLOATING TABLET OF CEPHALEXIN USING HYDROPHILIC POLYMERS
... Gastroretentive dosage forms significantly extend the period of time, over which drug may be released and thus prolong dosing intervals and increase patient compliance.4,5 Such retention systems are important for those drug that are degraded in the intestine like antacids or ...
... Gastroretentive dosage forms significantly extend the period of time, over which drug may be released and thus prolong dosing intervals and increase patient compliance.4,5 Such retention systems are important for those drug that are degraded in the intestine like antacids or ...
Prescribing Information
... Cases of benign and malignant liver tumors, which may lead to life-threatening intra-abdominal hemorrhage, have been observed after the use of Androcur. If severe upper abdominal complaints, liver enlargement or signs of intra-abdominal hemorrhage occur, a liver tumor should be included in the diffe ...
... Cases of benign and malignant liver tumors, which may lead to life-threatening intra-abdominal hemorrhage, have been observed after the use of Androcur. If severe upper abdominal complaints, liver enlargement or signs of intra-abdominal hemorrhage occur, a liver tumor should be included in the diffe ...
urine drug test information sheet barbiturates
... Prescribed Use: Induction of anesthesia, adjunct for intubation in head injury patients, control of convulsive states and treatment of intracranial pressure Mode of Use: IV injection Appearance: Powder for reconstitution as a solution for IV injection Metabolism and Precautions: Thiopental is a shor ...
... Prescribed Use: Induction of anesthesia, adjunct for intubation in head injury patients, control of convulsive states and treatment of intracranial pressure Mode of Use: IV injection Appearance: Powder for reconstitution as a solution for IV injection Metabolism and Precautions: Thiopental is a shor ...
Thyro-Tabs® - Vhsvets.com
... The clinical effects of levothyroxine sodium therapy are slow in being manifested. Overdosage of any thyroid drug may produce the signs and symptoms of thyrotoxicosis including, but not limited to: polydypsia, polyuria, polyphagia, reduced heat tolerance and hyperactivity or personality change. Thyr ...
... The clinical effects of levothyroxine sodium therapy are slow in being manifested. Overdosage of any thyroid drug may produce the signs and symptoms of thyrotoxicosis including, but not limited to: polydypsia, polyuria, polyphagia, reduced heat tolerance and hyperactivity or personality change. Thyr ...
Expert Opinion as to What “One Would Expect” is Speculation, not
... formulating a new drug. It would not be known whether any particular formulation would work, let alone provide the rapid onset found in the patented formulation. However, the Court observed that textbooks in the area noted that the task was not so daunting, stating “It will become obvious to the for ...
... formulating a new drug. It would not be known whether any particular formulation would work, let alone provide the rapid onset found in the patented formulation. However, the Court observed that textbooks in the area noted that the task was not so daunting, stating “It will become obvious to the for ...
develpoment and evaluation of sustained release formulations of
... In the present study, Venlafaxine was chosen as a model drug which is a Anti-Depressant. Because of its short life (5-11hr) and its high water solubility it was chosen as a suitable candidate for sustain matrix tablet formulation. It was formulated in to matrix tablet using hydrophilic polymer such ...
... In the present study, Venlafaxine was chosen as a model drug which is a Anti-Depressant. Because of its short life (5-11hr) and its high water solubility it was chosen as a suitable candidate for sustain matrix tablet formulation. It was formulated in to matrix tablet using hydrophilic polymer such ...
Tablet (pharmacy)
![](https://commons.wikimedia.org/wiki/Special:FilePath/FlattenedRoundPills.jpg?width=300)
A tablet is a pharmaceutical dosage form. Tablets may be defined as the solid unit dosage form of medicament or medicaments with or without suitable diluents and prepared either by molding or by compression. It comprises a mixture of active substances and excipients, usually in powder form, pressed or compacted from a powder into a solid dose. The excipients can include diluents, binders or granulating agents, glidants (flow aids) and lubricants to ensure efficient tabletting; disintegrants to promote tablet break-up in the digestive tract; sweeteners or flavours to enhance taste; and pigments to make the tablets visually attractive. A polymer coating is often applied to make the tablet smoother and easier to swallow, to control the release rate of the active ingredient, to make it more resistant to the environment (extending its shelf life), or to enhance the tablet's appearance.The compressed tablet is the most popular dosage form in use today. About two-thirds of all prescriptions are dispensed as solid dosage forms, and half of these are compressed tablets. A tablet can be formulated to deliver an accurate dosage to a specific site; it is usually taken orally, but can be administered sublingually, buccally, rectally or intravaginally. The tablet is just one of the many forms that an oral drug can take such as syrups, elixirs, suspensions, and emulsions. Medicinal tablets were originally made in the shape of a disk of whatever color their components determined, but are now made in many shapes and colors to help distinguish different medicines. Tablets are often stamped with symbols, letters, and numbers, which enable them to be identified. Sizes of tablets to be swallowed range from a few millimeters to about a centimeter.