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The celiac risk factors L. Greco
The celiac risk factors L. Greco

... (PAMPs) GLUTEN??? and mediate the production of cytokines necessary for the development of effective immunity. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. ...
Sjogren's Syndrome
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... Their apoptosis or expansion is regulated through Fas pathways that are modulated by cytokines and bcl-2 ...
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... 22. Is the following sentence true or false? Antibodies can fight viruses but not bacteria. 23. Label the antigen-binding sites in the drawing below. ...
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... • Tonsils are modified nodes of the throat, this position allows quick attack on inhaled or ingested pathogens ...
Hemophagocytic Lymphohistiocytosis (HLH)
Hemophagocytic Lymphohistiocytosis (HLH)

... Localized disease-skin, bone, lymph nodes  Good prognosis  Minimal/no treatment  Localized skin lesions, especially in infants, can regress spontaneously  If treatment is required, topical corticosteroids may be tried  Intralesional steroids ...
Transplantation Immunology October 1st, 2003 HHSC 401 Outline
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... Types of Grafts • Autologous (self) • e.g., BM, peripheral blood stem cells, skin, bone • Syngeneic (identical twin) • Allogeneic (another human except identical twin) ...
The Case of Baby Joe: Chronic Infections in an Infant
The Case of Baby Joe: Chronic Infections in an Infant

... Part III—Proteins Required for B and T Cell Development Baby Joe’s doctors diagnosed his condition as severe combined immunodeficiency (SCID). This disease is life-threatening; without treatment, it is usually fatal in childhood. SCID can be caused by several genetic mutations. Many of these mutatio ...
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Lab Dx Day 1 Intro to Hematopoietic System

... morning and high in late afternoon Newborn normal (1020,000) and gradually decreases until age 21 ...
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Comprehensive cancer care with a multidisciplinary approach

... Consultation with a transplant center early in the course of disease helps ensure that if a transplant is indicated, it is performed at an optimal time for the patient. We provide guidelines for timing of transplant consultation that specify which patients are at risk for disease progression and who ...
Alterations in White Blood Cells
Alterations in White Blood Cells

... Multiple myeloma is a plasma cell cancer of the osseous tissue and accounts for 10% to 15% of all hematologic malignancies. It is characterized by the uncontrolled proliferation of an abnormal clone of plasma cells, which secrete primarily IgG or IgA. There is an atypical proliferation of one of the ...
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... • Biologic Agents—the new “holy target” based on success in RA; however, biologics have been disappointing in SLE and SS (we will deal with these later in talk). • Cytotoxics such as cyclophosphamide—although we worry about cyclophosphamide, we need to ask how much is actually justified if we use ca ...
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Burkitt`s Lymphoma

... Later research showed that B-lymphocytes in these children had been infected with the Epstein-Barr virus (or E-B virus). Epstein-Barr virus infections are known as glandular fever or infectious mononucleosis: they are common and usually cause no problems, but in central Africa many of the children h ...
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... macrophages, T-helper cells and B-plasma cells ...
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... Immunodeficiency diseases occur when the immune system is less active than normal, resulting in recurring and life-threatening infections. Immunodeficiency can either be the result of a genetic disease, such as severe combined immunodeficiency, or be produced by pharmaceuticals or an infection, such ...
CHAPTER 16: LYMPHATIC SYSTEM AND IMMUNITY OBJECTIVES
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... Injection of gamma globulin with ready (PASSIVE) made antibodies. No immune response, short term immunity. ...
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... – Activate immune system by stimulating lymphocyte proliferation ...
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... The class of antibody is determined by the structure of the constant region Monomers – single Y-shaped molecules Dimers – paired Y-shaped molecules Pentamers – clusters of 5 Y-shaped molecules linked ...
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THE BODY`S DEFENSES
THE BODY`S DEFENSES

... produce chemicals called antibodies. Antibodies bind to the antigens on a pathogen, inactivate the pathogen, and mark them for destruction by other immune cells. Each kind of B-cell produces an antibody that bind to only one kind of antigen. Acquired immune deficiency syndrome, or AIDS, is a disease ...
kdfkdfjsdk - Austin Community College
kdfkdfjsdk - Austin Community College

...  Most important HLA are types A, B (MHC I) and DR (MHC II)  MHC I present antigens to cytotoxic T cells and MHC II use antigenpresenting cells for helper T cells  For this reason, it is important to have closely matched HLA between donor and recipient to avoid rejection, i.e., to avoid donor cell ...
chapter 13 t-cell/b-cell cooperation in humoral immunity
chapter 13 t-cell/b-cell cooperation in humoral immunity

... adulthood, a condition known as runting syndrome. However, runting only developed if thymectomy was carried out within the first 24 hours of birth -- thymectomy in older mice had little or no effect, consistent with the results of the earlier experiments referred to above. The cause of runting in th ...
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... Macrophages Macrophages, which also become widely distributed throughout the lymphoid organs and connective tissues, arise from monocytes formed in the bone marrow. They act as antigen presenters in the specific defense system. Macrophages also secrete cytokine proteins, called monokines, that are i ...
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X-linked severe combined immunodeficiency

X-linked severe combined immunodeficiency (X-SCID) is an immunodeficiency disorder in which the body produces very few T cells and NK cells. In the absence of T cell help, B cells become defective. It is an x-linked recessive trait, stemming from a mutated (abnormal) version of the IL2-RG gene located at xq13.1 on the X-chromosome, which is shared between receptors for IL-2, IL-4, IL-7, IL-9, IL-15 and IL-21.
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