
Anti-biotic Resistance
... in 1992, 13,300 hospital patients died of antibioticresistant bacterial infections cost of treating hospital infections is $1-3 billion/yr Patients with noscomial bacteremia spend $3,600 more in direct hospital costs, and remain in hospital 14 days longer than uninfected patients. 500,000 patients i ...
... in 1992, 13,300 hospital patients died of antibioticresistant bacterial infections cost of treating hospital infections is $1-3 billion/yr Patients with noscomial bacteremia spend $3,600 more in direct hospital costs, and remain in hospital 14 days longer than uninfected patients. 500,000 patients i ...
Information on Staphylococcal Infections
... penicillins, including Augmentin ®, dicloxacillin, or other methicillin-related antibiotics. These bacteria are also resistant to the cephalosporins. Consequently, the treatment is often longer, more expensive, and more complicated, with frequent recurrence of infections. Depending on the antibiotic ...
... penicillins, including Augmentin ®, dicloxacillin, or other methicillin-related antibiotics. These bacteria are also resistant to the cephalosporins. Consequently, the treatment is often longer, more expensive, and more complicated, with frequent recurrence of infections. Depending on the antibiotic ...
What is MRSA? A Powerpoint Presentation
... channels that drain to lymph glands, causing red streaks in the skin • Osteomyelitis – a bone infection • Paronychia – an infection of the skin folds of the ...
... channels that drain to lymph glands, causing red streaks in the skin • Osteomyelitis – a bone infection • Paronychia – an infection of the skin folds of the ...
Gum Disease Treatment
... very expensive drug; and the cost also includes all of the nursing care that is involved. Resulted Health Care costs for treating Defficil was estimated to exceed in this country more than 1 Billion dollars a year. Just from one side effect of antibiotic use. And so his recommendation regarding the ...
... very expensive drug; and the cost also includes all of the nursing care that is involved. Resulted Health Care costs for treating Defficil was estimated to exceed in this country more than 1 Billion dollars a year. Just from one side effect of antibiotic use. And so his recommendation regarding the ...
Keypads with CuVerro® Keys - Bactericidal Copper Keyboards
... Available in either x-y matrix or USB * Laboratory testing shows that, when cleaned regularly, CuVerro surfaces kill greater than 99.9% of the following bacteria within 2 hours of exposure: Methicillin-Resistant Staphylococcus aureus, Staphylococcus aureus, Entrerobacter aerogenes, Pseudomonas aerug ...
... Available in either x-y matrix or USB * Laboratory testing shows that, when cleaned regularly, CuVerro surfaces kill greater than 99.9% of the following bacteria within 2 hours of exposure: Methicillin-Resistant Staphylococcus aureus, Staphylococcus aureus, Entrerobacter aerogenes, Pseudomonas aerug ...
CASE 1: IMPETIGO
... the adherence to the extracellular matrix are collectively organized under the term MSCRAMM (microbial surface components recognizing adhesive matrix molecules).[14] Within this term, many proteins have been suggested to play important roles for S. aureus adhesion, but the two most notable ones are ...
... the adherence to the extracellular matrix are collectively organized under the term MSCRAMM (microbial surface components recognizing adhesive matrix molecules).[14] Within this term, many proteins have been suggested to play important roles for S. aureus adhesion, but the two most notable ones are ...
fcs102607
... Source: Peggy Riley, HEEL Specialist Outbreaks of resistant forms of staph infections have been making the news around the country in recent weeks. This highly contagious infection comes from the staphylococcus aureus bacteria that are normally found on the skin. The resistant strain recently appear ...
... Source: Peggy Riley, HEEL Specialist Outbreaks of resistant forms of staph infections have been making the news around the country in recent weeks. This highly contagious infection comes from the staphylococcus aureus bacteria that are normally found on the skin. The resistant strain recently appear ...
Example Needs Statement from: Infectious Disease Case
... and chemotherapy stirred interest in the idea that certain drugs may produce improved outcomes when targeted to a specific histologicalsubtype: in the case of bevacizumab, the nonsquamous subtype.2, (NEEDS DOCUMENT: Recent Research)Our in-depth analysis indicates that oncologists and hematologists h ...
... and chemotherapy stirred interest in the idea that certain drugs may produce improved outcomes when targeted to a specific histologicalsubtype: in the case of bevacizumab, the nonsquamous subtype.2, (NEEDS DOCUMENT: Recent Research)Our in-depth analysis indicates that oncologists and hematologists h ...
Marine Natural Products Chemistry
... Bacteria often live as a community encased in a protective extracellular matrix (biofilm) attached to a biotic or abiotic surface. ...
... Bacteria often live as a community encased in a protective extracellular matrix (biofilm) attached to a biotic or abiotic surface. ...
Micro: Lecture 17: Gram-Positive Bacteria Study Objectives •List
... −Toxins are heat-stable so reheating food does not inactivate toxins (cannot taste in food) −Antibiotics are not useful Toxic Shock Syndrome Toxin-1 •A superantigen toxin that results in release cytokines causing fever, capillary leakage, circulatory collapse and shock •Superantigen toxins also prev ...
... −Toxins are heat-stable so reheating food does not inactivate toxins (cannot taste in food) −Antibiotics are not useful Toxic Shock Syndrome Toxin-1 •A superantigen toxin that results in release cytokines causing fever, capillary leakage, circulatory collapse and shock •Superantigen toxins also prev ...
Antibiotic Reading for Lab
... these powerful drugs. While antibiotic resistance benefits the microbes, it presents humans with two big problems: it makes it more difficult to purge infections from the body; and it heightens the risk of acquiring infections in a hospital. Diseases such as tuberculosis, gonorrhea, malaria, and chi ...
... these powerful drugs. While antibiotic resistance benefits the microbes, it presents humans with two big problems: it makes it more difficult to purge infections from the body; and it heightens the risk of acquiring infections in a hospital. Diseases such as tuberculosis, gonorrhea, malaria, and chi ...
What is MRSA (Methycillin Resistant Staphylococcus Aureus)
... What is MRSA (Methycillin Resistant Staphylococcus Aureus)? In layman’s words – it is a bacteria found in human noses and mouths, on human hands and on many surfaces in our environment that when given entry into an open wound causes a serious infection because the bacteria is resistant to many antib ...
... What is MRSA (Methycillin Resistant Staphylococcus Aureus)? In layman’s words – it is a bacteria found in human noses and mouths, on human hands and on many surfaces in our environment that when given entry into an open wound causes a serious infection because the bacteria is resistant to many antib ...
Lecture 15 and 16 Microbiology: Gram Positive Bacteria infections
... • Permits invasion of tissues and dissolves fibrin clots formed by coagulase, respectively (break through tissue layers and go through tissue damage) − *Bacteremia: when there is bacteria in blood stream; immune system isn’t clearing it Diagnosis • Culture − Pus/surface swab, blood, sputum specimen ...
... • Permits invasion of tissues and dissolves fibrin clots formed by coagulase, respectively (break through tissue layers and go through tissue damage) − *Bacteremia: when there is bacteria in blood stream; immune system isn’t clearing it Diagnosis • Culture − Pus/surface swab, blood, sputum specimen ...
Antimicrobial resistance among bacterial pathogens
... infections are considered the number one in the low income countries and the fourth killer in the developed countries. Most of the infections are caused by bacteria Antibiotics are the only drugs for these bacterial diseases ...
... infections are considered the number one in the low income countries and the fourth killer in the developed countries. Most of the infections are caused by bacteria Antibiotics are the only drugs for these bacterial diseases ...
Veterinary Microbiology 108 (2005) 145-148
... 'University of Pennsylvania, New Bolton Center, 382 West St Rd, Kennett Sq., PA 19148, USA Received 19 November 2004; received in revised form 17 February 2005; accepted 18 February 2005 ...
... 'University of Pennsylvania, New Bolton Center, 382 West St Rd, Kennett Sq., PA 19148, USA Received 19 November 2004; received in revised form 17 February 2005; accepted 18 February 2005 ...
Global resistance trends and the potential impact of Methicillin
... cytolytic toxins (α and β hemolysins), exfoliative toxins, Panton-Valentine leukocidin (PVL), protein A, and several enzymes [16]. Important virulence factor in S. aureus is PVL, a member of the recently described family of synergohymenotropic toxins. PVL damages the membranes of host defense cells ...
... cytolytic toxins (α and β hemolysins), exfoliative toxins, Panton-Valentine leukocidin (PVL), protein A, and several enzymes [16]. Important virulence factor in S. aureus is PVL, a member of the recently described family of synergohymenotropic toxins. PVL damages the membranes of host defense cells ...
Novel DNA Supercoiling Inhibitors
... intravenous and oral administration Efficacious in multiple rodent models of Grampositive and Gram-negative infections Chemically tractable and scalable synthetic routes, with an attractive safety profile ...
... intravenous and oral administration Efficacious in multiple rodent models of Grampositive and Gram-negative infections Chemically tractable and scalable synthetic routes, with an attractive safety profile ...
Understanding the Enemy: Calming the Panic When New
... UK and Ireland: Both countries scored low for UAI but high for MAS. In this mindset, targets work well. ...
... UK and Ireland: Both countries scored low for UAI but high for MAS. In this mindset, targets work well. ...
National Skin Centre, Singapore
... in the United Kingdom in 1961, two years after the introduction of methicillin. MRSA is a recognized pathogen among hospitalized patients and persons with certain healthcare-associated risk factors. Recent reports suggest that the frequency of MRSA infections among otherwise healthy persons without ...
... in the United Kingdom in 1961, two years after the introduction of methicillin. MRSA is a recognized pathogen among hospitalized patients and persons with certain healthcare-associated risk factors. Recent reports suggest that the frequency of MRSA infections among otherwise healthy persons without ...
Bacterial_Pathogensis_Impetigo
... • When S. aureus is a skin commensal: • they utilize adhesive molecules called MSCRAMMs that bind to host epithelial cells • Clumping factor B and Teichoic acid are the MSCRAMMs that facilitate adherence to the host epithelial cells • Breakage in the skin barrier: • Endothelial and Epithelial cells ...
... • When S. aureus is a skin commensal: • they utilize adhesive molecules called MSCRAMMs that bind to host epithelial cells • Clumping factor B and Teichoic acid are the MSCRAMMs that facilitate adherence to the host epithelial cells • Breakage in the skin barrier: • Endothelial and Epithelial cells ...
Methicillin-resistant Staphylococcus aureus (MRSA): focus on
... predominantly carry SCCmec type IV, which is smaller in size than the gene cassette found in most HA strains (type I-III). This observed SCC size differential may allow for more efficient transfer of resistance among different bacteria, a factor which may be relevant in the alarmingly rapid emergenc ...
... predominantly carry SCCmec type IV, which is smaller in size than the gene cassette found in most HA strains (type I-III). This observed SCC size differential may allow for more efficient transfer of resistance among different bacteria, a factor which may be relevant in the alarmingly rapid emergenc ...
Bacterial Diseases
... • One of the most common communicable diseases in the United States is gonorrhea, an STD caused by Neisseria gonorrhoeae. How does it attach to the tissues? How does it spread? What is its only natural host? What is its most common symptoms? When do ...
... • One of the most common communicable diseases in the United States is gonorrhea, an STD caused by Neisseria gonorrhoeae. How does it attach to the tissues? How does it spread? What is its only natural host? What is its most common symptoms? When do ...
Pathogenic Cocci
... classified according to their hemolytic enzymes and cell wall antigens. Group A beta-hemolytic streptococci (including Streptococcus pyogenes) are the pathogens most important to humans. Produce a number of virulence factors: M protein, erythrogenic toxin, deoxyribonuclease, streptokinases, ...
... classified according to their hemolytic enzymes and cell wall antigens. Group A beta-hemolytic streptococci (including Streptococcus pyogenes) are the pathogens most important to humans. Produce a number of virulence factors: M protein, erythrogenic toxin, deoxyribonuclease, streptokinases, ...
Staphylococcus aureus

Staphylococcus aureus is a gram-positive coccal bacterium that is a member of the Firmicutes, and is frequently found in the respiratory tract and on the skin. It is often positive for catalase and nitrate reduction. Although S. aureus is not always pathogenic, it is a common cause of skin infections such as abscesses, respiratory infections such as sinusitis, and food poisoning. Pathogenic strains often promote infections by producing potent protein toxins, and expressing cell-surface proteins that bind and inactivate antibodies. The emergence of antibiotic-resistant forms of S. aureus such as MRSA is a worldwide problem in clinical medicine.Staphylococcus was first identified in 1880 in Aberdeen, Scotland, by the surgeon Sir Alexander Ogston in pus from a surgical abscess in a knee joint. This name was later appended to Staphylococcus aureus by Friedrich Julius Rosenbach, who was credited by the official system of nomenclature at the time. An estimated 20% of the human population are long-term carriers of S. aureus which can be found as part of the normal skin flora and in the nostrils. S. aureus is the most common species of Staphylococcus to cause Staph infections and is a successful pathogen due to a combination of nasal carriage and bacterial immunoevasive strategies.S. aureus can cause a range of illnesses, from minor skin infections, such as pimples, impetigo, boils, cellulitis, folliculitis, carbuncles, scalded skin syndrome, and abscesses, to life-threatening diseases such as pneumonia, meningitis, osteomyelitis, endocarditis, toxic shock syndrome, bacteremia, and sepsis. Its incidence ranges from skin, soft tissue, respiratory, bone, joint, endovascular to wound infections. It is still one of the five most common causes of hospital-acquired infections and is often the cause of postsurgical wound infections. Each year, around 500,000 patients in United States' hospitals contract a staphylococcal infection.