Two Linked Blood Pressure Quantitative Trait Loci on
... congenic strains derived from the progenitor strain. This original strain had a 74-cM segment from LEW rats introgressed into the S genetic background and showed a major lowering of BP by ⬇43 mm Hg compared with that of S. This has been reported previously.9 Congenic strains S.LEW⫻1 and S.LEW⫻6 were ...
... congenic strains derived from the progenitor strain. This original strain had a 74-cM segment from LEW rats introgressed into the S genetic background and showed a major lowering of BP by ⬇43 mm Hg compared with that of S. This has been reported previously.9 Congenic strains S.LEW⫻1 and S.LEW⫻6 were ...
Frequently Asked Questions (FAQs) What is this application related
... breeding or by genetic engineering using transgenes. A number of CMS systems have been tested in mustard. However, CMS/ restorer systems have been found to be inadequate for large scale hybrid seed production with high purity. CMS systems are either unstable or their restoration to fertility is inad ...
... breeding or by genetic engineering using transgenes. A number of CMS systems have been tested in mustard. However, CMS/ restorer systems have been found to be inadequate for large scale hybrid seed production with high purity. CMS systems are either unstable or their restoration to fertility is inad ...
Human respiratory mucins Human respiratory Lamblin, J.P.
... compounds to be clearly recognized as glycoproteins. However, the precise definition of mucins in general, as well as that of respiratory mucins, is still evolving due to the complexity of these molecules [1]. Initially, the definition of mucins was based on the chemical composition (from 50-80% car ...
... compounds to be clearly recognized as glycoproteins. However, the precise definition of mucins in general, as well as that of respiratory mucins, is still evolving due to the complexity of these molecules [1]. Initially, the definition of mucins was based on the chemical composition (from 50-80% car ...
PerfectBabyFullText
... context of reproduction are unavoidable, and are always made in a social context. People talk about perfect babies, whether or not they use a blueprint to define them. As the new reproductive and gene therapy technologies make diagnosis and cure of genetic anomalies possible, long-standing questions ...
... context of reproduction are unavoidable, and are always made in a social context. People talk about perfect babies, whether or not they use a blueprint to define them. As the new reproductive and gene therapy technologies make diagnosis and cure of genetic anomalies possible, long-standing questions ...
Chapter 10: Human Development
... fertilized egg and have identical genes. Dyzygotic, or fraternal, twins develop from two eggs and share only half of their genes, like any other sibling set. Studying sets of twins is a useful and informative way to know more about the influence of genes on behavior. ...
... fertilized egg and have identical genes. Dyzygotic, or fraternal, twins develop from two eggs and share only half of their genes, like any other sibling set. Studying sets of twins is a useful and informative way to know more about the influence of genes on behavior. ...
Application to Modify an Approved Exempt or Notifiable Low Risk
... Please initial each of the following statements to indicate that you understand your responsibilities when dealing with GMOs and then sign the application form. I have read, considered and understand my responsibilities under the Gene Technology Act 2000 and agree to undertake the GMO dealing outlin ...
... Please initial each of the following statements to indicate that you understand your responsibilities when dealing with GMOs and then sign the application form. I have read, considered and understand my responsibilities under the Gene Technology Act 2000 and agree to undertake the GMO dealing outlin ...
Aetiopathogenesis and Treatment of Vitiligo
... was the same as that in normal humans. The melanocytes from an uninvolved area of untreated vitiligo subjects can also not be passaged, i.e. they do not survive detachment by trypsinization, while melanocytes from normal humans survive many such detachments from culture dishes." The melanocytes from ...
... was the same as that in normal humans. The melanocytes from an uninvolved area of untreated vitiligo subjects can also not be passaged, i.e. they do not survive detachment by trypsinization, while melanocytes from normal humans survive many such detachments from culture dishes." The melanocytes from ...
A Novel Mouse Chromosome 17 Hybrid Sterility Locus
... 1991). The genotypes of all hybrid mice used in this study are described by a notation which takes the following form: X. [Y/Z]. The first letter, outside the brackets, is indicative of the genetic background of the animal. Letters inside the brackets, separated by a "/," symbolize the chromosome I7 ...
... 1991). The genotypes of all hybrid mice used in this study are described by a notation which takes the following form: X. [Y/Z]. The first letter, outside the brackets, is indicative of the genetic background of the animal. Letters inside the brackets, separated by a "/," symbolize the chromosome I7 ...
Hybrid Dysfunction: Population Genetic and Quantitative Genetic
... Demuth and Wade (2005) sought to compare the TurelliOrr model of hybrid dysfunction with a traditional quantitative genetics model with additive, dominance, and epistatic effects that can be estimated from line-cross data. They concluded that the two approaches can be understood in common terms when ...
... Demuth and Wade (2005) sought to compare the TurelliOrr model of hybrid dysfunction with a traditional quantitative genetics model with additive, dominance, and epistatic effects that can be estimated from line-cross data. They concluded that the two approaches can be understood in common terms when ...
View our poster (1.1 MB PDF)
... plasma PCSK9 protein and up to a 77% reduction in LDL-C. Moreover, the effect was maintained with very little fluctuation over 190 days of dosing. Safety studies in Rat and NHP at doses up to 300 mg/kg (multi-dose) showed that ALN-PCSsc was safe, demonstrating potential for a very wide therapeutic i ...
... plasma PCSK9 protein and up to a 77% reduction in LDL-C. Moreover, the effect was maintained with very little fluctuation over 190 days of dosing. Safety studies in Rat and NHP at doses up to 300 mg/kg (multi-dose) showed that ALN-PCSsc was safe, demonstrating potential for a very wide therapeutic i ...
The Human Genome Project: Genetic Screening and the
... (T), and Cystosine (C).'" There are two sets of the chain-base combination, and the bases from each chain attract each other and always pair up in the exact same way: (A) always pairs with (T), and (G) always pairs with (C). As the bases pair up, the chains wrap around one another, thus forming the ...
... (T), and Cystosine (C).'" There are two sets of the chain-base combination, and the bases from each chain attract each other and always pair up in the exact same way: (A) always pairs with (T), and (G) always pairs with (C). As the bases pair up, the chains wrap around one another, thus forming the ...
ANP 307 - National Open University of Nigeria
... all eight assignments in which case the best five of the eight assignments will be counted. The Tutor Marked Assignments (TMA) questions for the units in this course are contained in the assignment file. When you have completed each assignment, send it, together with a TMA form to your Tutor; make s ...
... all eight assignments in which case the best five of the eight assignments will be counted. The Tutor Marked Assignments (TMA) questions for the units in this course are contained in the assignment file. When you have completed each assignment, send it, together with a TMA form to your Tutor; make s ...
Estimates of Selection and Gene Flow From Measures of
... and that u rz 2.6 km. In erato, the shapes of the clines agreed with that expected on the basis of dominance. Heliconius melpomene has a nearly coincident hybrid zone. In this species, cline widths at four major color pattern loci varied between 1 1.7 and 13.4km. Pairwise gametic correlations peaked ...
... and that u rz 2.6 km. In erato, the shapes of the clines agreed with that expected on the basis of dominance. Heliconius melpomene has a nearly coincident hybrid zone. In this species, cline widths at four major color pattern loci varied between 1 1.7 and 13.4km. Pairwise gametic correlations peaked ...
Production of Vocalizations in Mammals
... At the opposite end of the frequency spectrum, some rodents, primates, and bats can produce ultrasonic vocalizations with fundamental frequencies of 40 kHz and higher (Suthers and Fattu, 1973). Adaptations of the middle ear and cochlea allow most mammals to hear high frequencies (above 10 kHz) that ...
... At the opposite end of the frequency spectrum, some rodents, primates, and bats can produce ultrasonic vocalizations with fundamental frequencies of 40 kHz and higher (Suthers and Fattu, 1973). Adaptations of the middle ear and cochlea allow most mammals to hear high frequencies (above 10 kHz) that ...
A Genetic Linkage Map of Mouse Chromosome 10
... et al. 1988). Third, molecular genetic linkage maps have been used for comparative mapping between mouse and human (or other) genomes [reviewed by NADEAU(1989) and SEARLE et al. (1 989)]. Comparative mapping can ultimately lead to the identification of mouse models of human diseases (BRUETON et a l ...
... et al. 1988). Third, molecular genetic linkage maps have been used for comparative mapping between mouse and human (or other) genomes [reviewed by NADEAU(1989) and SEARLE et al. (1 989)]. Comparative mapping can ultimately lead to the identification of mouse models of human diseases (BRUETON et a l ...
Human Senescence - Assets - Cambridge University Press
... all aspects of human life history. This biocultural complexity is often slighted or not fully conveyed in both sociocultural and biological studies of human senescence and life span. As gerontologists have turned their attention to individual and population variation in human senescence and to the s ...
... all aspects of human life history. This biocultural complexity is often slighted or not fully conveyed in both sociocultural and biological studies of human senescence and life span. As gerontologists have turned their attention to individual and population variation in human senescence and to the s ...
Identifying the genomic determinants of aging and longevity in
... Human life expectancy has increased remarkably over the last two centuries worldwide [1], although it is still highly variable between countries [2]. This lifespan extension is mainly due to improvement of health care, hygiene, and nutrition. The healthy life expectancy, however, has not increased a ...
... Human life expectancy has increased remarkably over the last two centuries worldwide [1], although it is still highly variable between countries [2]. This lifespan extension is mainly due to improvement of health care, hygiene, and nutrition. The healthy life expectancy, however, has not increased a ...
Functional variation of MC1R alleles from red
... are uniformly black (11). Surprisingly, mice that lack proopiomelanocortin (POMC), the precursor of αMSH, are not yellow but are quite dark (15), suggesting that there is substantial ligand-independent signalling from MC1R. Furthermore, these mice show an agouti pattern on their hairs, indicating th ...
... are uniformly black (11). Surprisingly, mice that lack proopiomelanocortin (POMC), the precursor of αMSH, are not yellow but are quite dark (15), suggesting that there is substantial ligand-independent signalling from MC1R. Furthermore, these mice show an agouti pattern on their hairs, indicating th ...
EXCHANGE OF GENETIC MATERIAL BETWEEN
... Transfer of the Hfr character from E. coli to Salmonella: It is known that the Hfr character, unlike the F+ character, is not transferable to F- cells by infection but can be transferred by conjugation (BERNSTEIN1958); in other words, the factor responsible for Hfr is located on the bacterial chromo ...
... Transfer of the Hfr character from E. coli to Salmonella: It is known that the Hfr character, unlike the F+ character, is not transferable to F- cells by infection but can be transferred by conjugation (BERNSTEIN1958); in other words, the factor responsible for Hfr is located on the bacterial chromo ...
Preliminary study on resynthesis of winter oilseed - IHAR
... crossing between progenitor species with yellow or brown seeds will cause introgression of this trait (Zaman 1988). Yellow seeded oilseed rape lines are characterized by a thinner seed coats, which is a source of fiber in the seeds, and tend to have higher fat and protein content than brown or black ...
... crossing between progenitor species with yellow or brown seeds will cause introgression of this trait (Zaman 1988). Yellow seeded oilseed rape lines are characterized by a thinner seed coats, which is a source of fiber in the seeds, and tend to have higher fat and protein content than brown or black ...
Methods and Logic: Gregor Mendel Experiments in Plant
... • Mendel chose to pick two differentiating characteristics and unite them by cross fertilization. • He utilized male and female plants to cross and make his first generation. • Some possible experimental errors that he mentioned were: – Bug contamination: Buchus pisi – Unwanted pollination from othe ...
... • Mendel chose to pick two differentiating characteristics and unite them by cross fertilization. • He utilized male and female plants to cross and make his first generation. • Some possible experimental errors that he mentioned were: – Bug contamination: Buchus pisi – Unwanted pollination from othe ...
Xenobiotic-metabolizing cytochrome P450 enzymes in human lung
... xenobiotics, including most of the therapeutic drugs and environmental pollutants (Nelson et al. 1996, Bertz & Granneman 1997). The first report on the existence of a CYP enzyme or a “microsomal carbon monoxide-binding pigment”, as it was called at that time, was published in 1958 by Klingenberg et ...
... xenobiotics, including most of the therapeutic drugs and environmental pollutants (Nelson et al. 1996, Bertz & Granneman 1997). The first report on the existence of a CYP enzyme or a “microsomal carbon monoxide-binding pigment”, as it was called at that time, was published in 1958 by Klingenberg et ...
Multiple Quantitative Trait Loci Modify Cochlear Hair Cell
... are electromotile amplifiers of auditory stimuli that can be functionally assessed by distortion product otoacoustic emission (DPOAE) analysis. When C3H-Tmc1Bth/Bth is crossed with either C57BL/6J or DBA/2J wild-type mice, F1 hybrid Tmc1Bth/1 progeny have increased hearing loss associated with incre ...
... are electromotile amplifiers of auditory stimuli that can be functionally assessed by distortion product otoacoustic emission (DPOAE) analysis. When C3H-Tmc1Bth/Bth is crossed with either C57BL/6J or DBA/2J wild-type mice, F1 hybrid Tmc1Bth/1 progeny have increased hearing loss associated with incre ...
Previous releases and international approvals
... IOGTR identified a number of instances of non-compliance with GMAC conditions, as detailed in IOGTR Quarterly Reports. Some of these instances of non-compliance related to trials of InVigor canola, specifically PR-63X(4) and PR-62X(4). In some of these instances Bayer notified the IOGTR of the non- ...
... IOGTR identified a number of instances of non-compliance with GMAC conditions, as detailed in IOGTR Quarterly Reports. Some of these instances of non-compliance related to trials of InVigor canola, specifically PR-63X(4) and PR-62X(4). In some of these instances Bayer notified the IOGTR of the non- ...
Human–animal hybrid
The term human–animal hybrid or animal–human hybrid refers to an entity that incorporates elements from both humans and non-human animals. For thousands of years, these hybrids have been one of the most common themes in storytelling about animals throughout the world. The lack of a strong divide between humanity and animal nature in multiple traditional and ancient cultures has provided the underlying historical context for the popularity of tales where humans and animals have mingling relationships, such as in which one turns into the other or in which some mixed being goes through a journey. Interspecies friendships within the animal kingdom, as well as between humans and their pets, additionally provides an underlying root for the popularity of such beings.In various mythologies throughout history, many particularly famous hybrids have existed, including as a part of Egyptian and Indian spirituality. According to artist and scholar Pietro Gaietto, ""representations of human-animal hybrids always have their origins in religion"". As well, ""successive traditions they may change in meaning but they still remain within spiritual culture"" in his view. The entities have also been characters in fictional media more recently in history such as in H.G. Wells' work The Island of Doctor Moreau, adapted into the popular 1932 film Island of Lost Souls. In legendary terms, the hybrids have play varying roles from that of trickster and/or villain to serving as divine heroes in very different contexts, depending on the given culture.For example, Pan is a deity in Greek mythology that rules over and symbolizes the untamed wild, being worshiped by hunters, fishermen, and shepherds in particular. The mischievous yet cheerful character has the hindquarters, legs, and horns of a goat while otherwise being essentially human in appearance, with stories of his encounters with different gods, humans, and others being retold for centuries on after the days of early Greece by groups such as the Delphian Society. Specifically, the human-animal hybrid has appeared in acclaimed works of art by figures such as Francis Bacon. Additional famous mythological hybrids include the Egyptian god of death, named Anubis, and the fox-like Japanese beings that are called Kitsune.When looked at scientifically, outside of a fictional and/or mythical context, the real-life creation of human-animal hybrids has served as a subject of legal, moral, and technological debate in the context of recent advances in genetic engineering. Defined by the magazine H+ as ""genetic alterations that are blendings [sic] of animal and human forms"", such hybrids may be referred by other names occasionally such as ""para-humans"". They may additionally may be called ""humanized animals"". Technically speaking, they are also related to ""cybrids"" (cytoplasmic hybrids), with ""cybrid"" cells featuring foreign human nuclei inside of them being a topic of interest. Possibly, a real-world human-animal hybrid may be an entity formed from either a human egg fertilized by a nonhuman sperm or a nonhuman egg fertilized by a human sperm. While at first being a concept in the likes of legends and thought experiments, the first stable human-animal chimeras (not hybrids but related) to actually exist were first created by Shanghai Second Medical University scientists in 2003, the result of having fused human cells with rabbit eggs. As well, a U.S. patent has notably been granted for a mouse chimera with a human immune system.In terms of scientific ethics, restrictions on the creation of human–animal hybrids have proved a controversial matter in multiple countries. While the state of Arizona banned the practice altogether in 2010, a proposal on the subject that sparked some interest in the United States Senate from 2011 to 2012 ended up going nowhere. Although the two concepts are not strictly related, discussions of experimentation into blended human and animal creatures has paralleled the discussions around embryonic stem-cell research (the 'stem cell controversy'). The creation of genetically modified organisms for a multitude of purposes has taken place in the modern world for decades, examples being specifically designed foodstuffs made to have features such as higher crop yields through better disease resistance.Despite the legal and moral controversy over the possible real-life making of such beings, then President George W. Bush even speaking on the subject in his 2006 State of the Union, the concept of humanoid creatures with hybrid characteristics from animals, played in a dramatic and sensationalized fashion, has continued to be a popular element of fictional media in the digital age. Examples include Splice, a 2009 movie about experimental genetic research, and The Evil Within, a survival horror video game released in 2014 in which the protagonist fights grotesque hybrid creatures among other enemies.