![Age-associated hyper-methylated regions in the human brain](http://s1.studyres.com/store/data/014588729_1-2a88d2163e2618996412ffb9573dc366-300x300.png)
Age-associated hyper-methylated regions in the human brain
... epigenetic modifications has so far only been identified with respect to age-associated hyper-methylated sites in blood. In this study, we observed that age-associated differentially methylated sites characterized in the human brain were also highly enriched in bivalent domains. Analysis of hyper- v ...
... epigenetic modifications has so far only been identified with respect to age-associated hyper-methylated sites in blood. In this study, we observed that age-associated differentially methylated sites characterized in the human brain were also highly enriched in bivalent domains. Analysis of hyper- v ...
Neural networks engaged in milliseconds and seconds time
... tasks has been reported in patients with lesions of the cerebellum in the range of both milliseconds and a few seconds (Ivry et al. 1988; Nichelli et al. 1996; Mangels et al. 1998). Malapani et al. (1998a,b), using a peak interval procedure, reported that the variability of time estimates increased ...
... tasks has been reported in patients with lesions of the cerebellum in the range of both milliseconds and a few seconds (Ivry et al. 1988; Nichelli et al. 1996; Mangels et al. 1998). Malapani et al. (1998a,b), using a peak interval procedure, reported that the variability of time estimates increased ...
Connectionist AI, symbolic AI, and the brain
... In the past few years a new approach to artificial intelligence (AI), called connectionist modelling, has been gaining increasing attention in research and d e v e l o p m e n t laboratories. Connectionist systems are large networks of extremely simple processors, massively interconnected and runnin ...
... In the past few years a new approach to artificial intelligence (AI), called connectionist modelling, has been gaining increasing attention in research and d e v e l o p m e n t laboratories. Connectionist systems are large networks of extremely simple processors, massively interconnected and runnin ...
Book of Abstracts - Oxygen Club of California
... Sun, A.Y. ..........................................65 Swaminathan, S. ............................ 113 Sykiotis, G.P. ................................. 122 ...
... Sun, A.Y. ..........................................65 Swaminathan, S. ............................ 113 Sykiotis, G.P. ................................. 122 ...
Lorazepam dose-dependently decreases risk-taking
... risk-taking behavior with gains and losses, respectively, were used to evaluate the neural systems response to the experienced outcome: (1) selecting a risky response (40 or 80), which resulted in reward; and (2) selecting a risky response, which resulted in punishment (−40 or −80). These regressors ...
... risk-taking behavior with gains and losses, respectively, were used to evaluate the neural systems response to the experienced outcome: (1) selecting a risky response (40 or 80), which resulted in reward; and (2) selecting a risky response, which resulted in punishment (−40 or −80). These regressors ...
1 Brain Development, SIDS and Shaken Baby By Rhonda Crabbs
... National Institute of Child Health and Human Development (NICHD) defines SIDS as the sudden death of an infant under one year of age, which remains unexplained after a thorough case investigation, which includes the performance of a complete autopsy, examination of the death scene and review of the ...
... National Institute of Child Health and Human Development (NICHD) defines SIDS as the sudden death of an infant under one year of age, which remains unexplained after a thorough case investigation, which includes the performance of a complete autopsy, examination of the death scene and review of the ...
Downloaded - Cisler Lab
... engaged by TF-CBT that enable its clinical outcomes. Subsequent efforts would then focus on identifying new ways to more effectively engage these key mechanisms during TF-CBT. Here, we report results from an exploratory study designed to provide initial data regarding the neural mechanisms engaged b ...
... engaged by TF-CBT that enable its clinical outcomes. Subsequent efforts would then focus on identifying new ways to more effectively engage these key mechanisms during TF-CBT. Here, we report results from an exploratory study designed to provide initial data regarding the neural mechanisms engaged b ...
Three approaches to investigating functional compromise to the
... with TAI (i.e., high-velocity motor vehicle collision (MVC) or MVC-pedestrian collision), 2) had either subcortical injury seen on Computed Tomography (CT) scan at admission or a post-resuscitation GCS 3-12 if CT was normal, 3) were hemodynamically stable so that transfer to the scanner was clinical ...
... with TAI (i.e., high-velocity motor vehicle collision (MVC) or MVC-pedestrian collision), 2) had either subcortical injury seen on Computed Tomography (CT) scan at admission or a post-resuscitation GCS 3-12 if CT was normal, 3) were hemodynamically stable so that transfer to the scanner was clinical ...
The epistemic value of brain-machine systems for the study of the
... sufficient to accurately predict hand position and velocity but not gripping force). The achievement of good performances in the successive “brain control” phase may be taken as indicative of decoder accuracy (even though, as often pointed out in the literature, efficient prosthetic control can be d ...
... sufficient to accurately predict hand position and velocity but not gripping force). The achievement of good performances in the successive “brain control” phase may be taken as indicative of decoder accuracy (even though, as often pointed out in the literature, efficient prosthetic control can be d ...
Effect of Language Switching on Arithmetic: A Bilingual fMRI Study
... 2004). Similarly, Munduruku subjects were able to compare and approximately add large numbers that are outside of their verbal count sequence, but failed in exact arithmetic with numbers larger than 4 (Pica et al., 2004). Thus, individuals from both Amazonian groups were unable to perform exact calc ...
... 2004). Similarly, Munduruku subjects were able to compare and approximately add large numbers that are outside of their verbal count sequence, but failed in exact arithmetic with numbers larger than 4 (Pica et al., 2004). Thus, individuals from both Amazonian groups were unable to perform exact calc ...
Differential functional connectivity of rostral
... college students. Participants completed the Penn State Worry Questionnaire (PSWQ; Meyer et al., 1990; Molina and Borkovec, 1994), which measures AP, and the Mood and Anxiety Symptom Questionnaire (MASQ; Watson et al., 1995a,b), which measures AR with the MASQ-AA subscale and AD with the MASQ-AD sub ...
... college students. Participants completed the Penn State Worry Questionnaire (PSWQ; Meyer et al., 1990; Molina and Borkovec, 1994), which measures AP, and the Mood and Anxiety Symptom Questionnaire (MASQ; Watson et al., 1995a,b), which measures AR with the MASQ-AA subscale and AD with the MASQ-AD sub ...
Memory Cure -- through ‘brain specific nutrients’?
... In animals, PS has been shown to attenuate many neuronal effects of aging, and to restore normal memory on a variety of tasks. Preliminary findings with humans, though, are limited. For older adults with probable Alzheimer's disease, a single study failed to demonstrate positive effects of PS on mem ...
... In animals, PS has been shown to attenuate many neuronal effects of aging, and to restore normal memory on a variety of tasks. Preliminary findings with humans, though, are limited. For older adults with probable Alzheimer's disease, a single study failed to demonstrate positive effects of PS on mem ...
Slide 1
... Recorded from MT neurons Quantify attentional effect by comparing the responses of individual MT neurons to identical visual display conditions when the monkey was instructed to attend to one or the other aperture Neuronal responses were measured as the number of spikes that the cell fired dur ...
... Recorded from MT neurons Quantify attentional effect by comparing the responses of individual MT neurons to identical visual display conditions when the monkey was instructed to attend to one or the other aperture Neuronal responses were measured as the number of spikes that the cell fired dur ...
Progress and Controversy in the Study of Posttraumatic Stress
... Unlike fear, which can be experienced by rats, guilt and shame are complex emotions which can only be experienced by animals possessing a sense of self. As the animal conditioning model reduces trauma to its biological basis, it does not capture this uniquely human aspect of trauma. ...
... Unlike fear, which can be experienced by rats, guilt and shame are complex emotions which can only be experienced by animals possessing a sense of self. As the animal conditioning model reduces trauma to its biological basis, it does not capture this uniquely human aspect of trauma. ...
datos de los autores
... SPECT findings on ADHD Amen et.al (26-27) divided ADD into 6 subtypes using SPECT. Type 1 or classic ADHD involves a normal resting brain, but during concentration there are decreases in metabolic activity on the topside (dorsolateral) and underside (orbito-frontal) prefrontal cortex. Thus, reduced ...
... SPECT findings on ADHD Amen et.al (26-27) divided ADD into 6 subtypes using SPECT. Type 1 or classic ADHD involves a normal resting brain, but during concentration there are decreases in metabolic activity on the topside (dorsolateral) and underside (orbito-frontal) prefrontal cortex. Thus, reduced ...
Age-related differences in brain activity underlying identification of
... Finally, the insula is thought to be critically involved in perceiving disgust (Phillips et al., 1997; Sprengelmeyer et al., 1998; Calder et al., 2000; Anderson et al., 2003), likely due to its role in visceral and somatosensory responses (Adolphs, 2002). The effect of aging on social cognition has ...
... Finally, the insula is thought to be critically involved in perceiving disgust (Phillips et al., 1997; Sprengelmeyer et al., 1998; Calder et al., 2000; Anderson et al., 2003), likely due to its role in visceral and somatosensory responses (Adolphs, 2002). The effect of aging on social cognition has ...
Background Paper 3 - Yale School of Medicine
... anatomical homology between rodent and primate prefrontal cortex is controversial49,50. However, studies of the infralimbic (IL) and prelimbic (PL) areas within rat medial PFC (mPFC), the most likely functional homologue of dlPFC in NHP and human, largely support the results from rhesus monkey. Firs ...
... anatomical homology between rodent and primate prefrontal cortex is controversial49,50. However, studies of the infralimbic (IL) and prelimbic (PL) areas within rat medial PFC (mPFC), the most likely functional homologue of dlPFC in NHP and human, largely support the results from rhesus monkey. Firs ...
The Anterior Midline Field: Coercion or decision making? Brain and
... (e.g., after the word break in the journalist began the article after his coffee break). In other words, one might hypothesize that the activity generating the AMF reflects the difficulty of sensicality judgments, and that those judgments are performed incrementally at each word and are the hardest fo ...
... (e.g., after the word break in the journalist began the article after his coffee break). In other words, one might hypothesize that the activity generating the AMF reflects the difficulty of sensicality judgments, and that those judgments are performed incrementally at each word and are the hardest fo ...
Not all brains are created equal: The relevance of
... strengths, such that 1mA and 2mA of A-tDCS achieve different outcomes on cognitive tasks. One study reports reduced reaction times with prolonged but not shorter stimulation periods at 2mA, whereas reaction times increased with longer stimulation times at 1mA (Teo et al., 2011). Reaction times were ...
... strengths, such that 1mA and 2mA of A-tDCS achieve different outcomes on cognitive tasks. One study reports reduced reaction times with prolonged but not shorter stimulation periods at 2mA, whereas reaction times increased with longer stimulation times at 1mA (Teo et al., 2011). Reaction times were ...
Responses of the Human Brain to Mild Dehydration and
... challenges of de- and rehydration by serial measurements of brain volume, tissue fluid, and metabolites. MATERIALS AND METHODS: Serial T1-weighted and 1H-MR spectroscopy data were acquired in 15 healthy individuals at normohydration, on 12 hours of dehydration, and during 1 hour of oral rehydration. ...
... challenges of de- and rehydration by serial measurements of brain volume, tissue fluid, and metabolites. MATERIALS AND METHODS: Serial T1-weighted and 1H-MR spectroscopy data were acquired in 15 healthy individuals at normohydration, on 12 hours of dehydration, and during 1 hour of oral rehydration. ...
collective intelligence
... The openness and inclusiveness to a lay community of contributors, makes the Missing Maps project an excellent case to discuss the specificity of collective intelligence. The project shows that single agents with minimal topical expertise can generate results through collaboration, the scale of whic ...
... The openness and inclusiveness to a lay community of contributors, makes the Missing Maps project an excellent case to discuss the specificity of collective intelligence. The project shows that single agents with minimal topical expertise can generate results through collaboration, the scale of whic ...
Brain and effort: brain activation and effort-related working
... KLS but not in healthy participants. The altered brain activation pattern in KLS patients was accompanied by lower performance levels and longer reaction times. In addition to functional differences between KLS and controls, we have also observed that the level of activation differs between individu ...
... KLS but not in healthy participants. The altered brain activation pattern in KLS patients was accompanied by lower performance levels and longer reaction times. In addition to functional differences between KLS and controls, we have also observed that the level of activation differs between individu ...
Choline Signal Changes after Choline
... a little boy with ADHD. Yet it was not until 1902 that Still (2) described a group of impulsive children with significant behavioral problems caused by a genetic dysfunction and not by poor child rearing children who still would be easily recognized as having ADHD. Since then, thousand scientific pa ...
... a little boy with ADHD. Yet it was not until 1902 that Still (2) described a group of impulsive children with significant behavioral problems caused by a genetic dysfunction and not by poor child rearing children who still would be easily recognized as having ADHD. Since then, thousand scientific pa ...
- Philsci
... Interestingly, the monkeys still moved their own limbs at the beginning of the “brain control” phase, even though these movements were no more functional to controlling the cursor; eventually, however, they ceased to produce hand movements while continuing to brain-control the cursor. Performances s ...
... Interestingly, the monkeys still moved their own limbs at the beginning of the “brain control” phase, even though these movements were no more functional to controlling the cursor; eventually, however, they ceased to produce hand movements while continuing to brain-control the cursor. Performances s ...
The Neural Bases of Cognitive Conflict and Control in Moral Judgment
... participants considered personal moral dilemmas, while “cognitive” brain areas associated with abstract reasoning and problem solving exhibited increased activity while participants considered impersonal moral dilemmas. Second, we found that reaction times (RTs) were, on average, considerably longer ...
... participants considered personal moral dilemmas, while “cognitive” brain areas associated with abstract reasoning and problem solving exhibited increased activity while participants considered impersonal moral dilemmas. Second, we found that reaction times (RTs) were, on average, considerably longer ...