Automated discovery of drug treatment patterns for endocrine
... used the manually abstracted treatment regimens from a prior breast cancer pharmacogenomic study to test the hypothesis that automatically extracted information from the EMR originally created by the practitioner at the point of care, coupled with computational techniques, is comparable to the infor ...
... used the manually abstracted treatment regimens from a prior breast cancer pharmacogenomic study to test the hypothesis that automatically extracted information from the EMR originally created by the practitioner at the point of care, coupled with computational techniques, is comparable to the infor ...
Full Article
... resonator each time the light travels past the binding site. If the detection site was simply on a waveguide, that slight change would probably be too small to detect. However, since the light in the resonator travels back and forth many times between entering and exiting the resonator, and the capt ...
... resonator each time the light travels past the binding site. If the detection site was simply on a waveguide, that slight change would probably be too small to detect. However, since the light in the resonator travels back and forth many times between entering and exiting the resonator, and the capt ...
Understanding Side Effects of Drug Therapy
... Program. For more information, call the World Trade Center Health Program at (888) 982-4748 or visit www.cdc.gov/wtc. Depression. Treatment for depression has proven benefits for people living with cancer. Depression is an illness that should be treated even when a person is undergoing cancer treatm ...
... Program. For more information, call the World Trade Center Health Program at (888) 982-4748 or visit www.cdc.gov/wtc. Depression. Treatment for depression has proven benefits for people living with cancer. Depression is an illness that should be treated even when a person is undergoing cancer treatm ...
Photostability
... determined to photodegrade upon direct exposure but is adequately protected by packaging, an in-use study may be needed to support the use of the product (e.g., a parenteral drug that is infused over a period of time). The test conditions for in-use studies will vary depending on the product and use ...
... determined to photodegrade upon direct exposure but is adequately protected by packaging, an in-use study may be needed to support the use of the product (e.g., a parenteral drug that is infused over a period of time). The test conditions for in-use studies will vary depending on the product and use ...
Chapter 55. Cancer Chemotherapy
... tumor heterogeneity. There may also be other tumor cells that reside in pharmacologic sanctuary sites (eg, the central nervous system, testes), where effective drug concentrations may be difficult to achieve. When cell cycle-specific drugs are used, the tumor stem cells must also be in the sensitive ...
... tumor heterogeneity. There may also be other tumor cells that reside in pharmacologic sanctuary sites (eg, the central nervous system, testes), where effective drug concentrations may be difficult to achieve. When cell cycle-specific drugs are used, the tumor stem cells must also be in the sensitive ...
Countering Drug Resistance in the Developing World: An Assessment of
... biotech companies have weak incentives to pay adequate attention to the impact of drug resistance or to develop new resistance friendly technologies and narrow spectrum antibiotics, especially those focused towards the developing world. Smaller biotech companies and large generic manufacturers have ...
... biotech companies have weak incentives to pay adequate attention to the impact of drug resistance or to develop new resistance friendly technologies and narrow spectrum antibiotics, especially those focused towards the developing world. Smaller biotech companies and large generic manufacturers have ...
Clinical Trials – The New Frontier of Cancer Treatment
... Limited collaboration between sponsors, academia, and funding sources • Traditional models not designed to address “niche” agents with very small populations expected to benefit Kaitin, KI, Dimasi JA. Pharmaceutical Innovation in the 21st century: new drug approvals in the first decade, 2000-2009. C ...
... Limited collaboration between sponsors, academia, and funding sources • Traditional models not designed to address “niche” agents with very small populations expected to benefit Kaitin, KI, Dimasi JA. Pharmaceutical Innovation in the 21st century: new drug approvals in the first decade, 2000-2009. C ...
Principles of Colloid and Interface Science
... Nanoscale Colloid and Interface Science is an important field of research and application in the industry. Many pharmaceutical and food products are formulated as disperse systems such as suspensions, emulsions, microemulsions, gels etc. These systems can vary from colloidal dispersions (covering th ...
... Nanoscale Colloid and Interface Science is an important field of research and application in the industry. Many pharmaceutical and food products are formulated as disperse systems such as suspensions, emulsions, microemulsions, gels etc. These systems can vary from colloidal dispersions (covering th ...
ADVANCES IN THERAPEUTIC PROTEIN PRODUCTION AND DELIVERY Review Article AMIT KUMAR NAYAK*
... During past few decades, therapeutic proteins have emerging in prominence as potential drug candidates for the future to treat patients suffering from various diseases like cancers, heart attacks, strokes, cystic fibrosis, diabetes, anemia, hemophilia, Gaucher’s di ...
... During past few decades, therapeutic proteins have emerging in prominence as potential drug candidates for the future to treat patients suffering from various diseases like cancers, heart attacks, strokes, cystic fibrosis, diabetes, anemia, hemophilia, Gaucher’s di ...
text building
... 2 The overall purpose of additives in modern food manufacture is the same as it was in the traditional kitchen – to prepare, preserve, process and, as the case may be, cook basic _______ ingredients to convert them into wholesome, attractive, better tasting and _______ food, ready to be consumed. 3 ...
... 2 The overall purpose of additives in modern food manufacture is the same as it was in the traditional kitchen – to prepare, preserve, process and, as the case may be, cook basic _______ ingredients to convert them into wholesome, attractive, better tasting and _______ food, ready to be consumed. 3 ...
Medicare Outpatient Oncology Reimbursement 2007
... 60 percent of payment is adjusted by the hospital ...
... 60 percent of payment is adjusted by the hospital ...
Metabolism and Excretion of Drugs
... for drug–drug pharmacokinetic interactions. The most common type of inhibition is simple competitive inhibition, wherein two drugs are vying for the same active site and the drug with the highest affinity for the site wins out. In this scenario, addition of a second drug with greater affinity for th ...
... for drug–drug pharmacokinetic interactions. The most common type of inhibition is simple competitive inhibition, wherein two drugs are vying for the same active site and the drug with the highest affinity for the site wins out. In this scenario, addition of a second drug with greater affinity for th ...
Table of Contents - International College of Health Sciences
... (ATP); name the enzyme involved in the conversion of hypoxanthine to xanthine and xanthine to uric acid; and compare and contrast the solubility of hypoxanthine, xanthine, and uric acid in body fluids (e.g., urine, synovial fluid). Summarize the mechanisms of action of allopurinol, probenecid, and c ...
... (ATP); name the enzyme involved in the conversion of hypoxanthine to xanthine and xanthine to uric acid; and compare and contrast the solubility of hypoxanthine, xanthine, and uric acid in body fluids (e.g., urine, synovial fluid). Summarize the mechanisms of action of allopurinol, probenecid, and c ...
Pyroelectrically Driven •OH Generation by Barium Titanate and
... aromatic rings. Living cells are damaged by radicals reacting with amino acids and DNA molecules.3 Photocatalytic E. coli inactivation with TiO2 showed cell damage caused by various ROS, such as OH radicals, hyperoxide radicals, and H2O2.4 Basically ROS react immediately at the place of their origin ...
... aromatic rings. Living cells are damaged by radicals reacting with amino acids and DNA molecules.3 Photocatalytic E. coli inactivation with TiO2 showed cell damage caused by various ROS, such as OH radicals, hyperoxide radicals, and H2O2.4 Basically ROS react immediately at the place of their origin ...
Provincial Working Group Report on the
... living better than at any other time in history. Five-year relative survival rates for patients with the four most common cancers is increasing (20% increase for prostate, 10% increase for breast, 6% increase for colorectal. Survival for lung cancer remains low at a 2% increase). This survival impro ...
... living better than at any other time in history. Five-year relative survival rates for patients with the four most common cancers is increasing (20% increase for prostate, 10% increase for breast, 6% increase for colorectal. Survival for lung cancer remains low at a 2% increase). This survival impro ...
Translational Research Success Stories
... treat the symptoms of AD and its causes. The Bredesen Laboratory at the Buck Institute for Research on Aging has been very active in the field of AD pathophysiology and has uncovered some interesting biology as to the amyloid precursor protein (APP) gene’s function as well as methods to control its ...
... treat the symptoms of AD and its causes. The Bredesen Laboratory at the Buck Institute for Research on Aging has been very active in the field of AD pathophysiology and has uncovered some interesting biology as to the amyloid precursor protein (APP) gene’s function as well as methods to control its ...
Nosy Neuroprotection
... ishemic brain damage. NAD+ was observed to reduce infarct formation by up to 86% even when administered at 2 hours after ischemic onset. Because PARP activation appears to be a downstream ischemic event, it may be worthwhile to also investigate the ability of IN administration of agents such as anti ...
... ishemic brain damage. NAD+ was observed to reduce infarct formation by up to 86% even when administered at 2 hours after ischemic onset. Because PARP activation appears to be a downstream ischemic event, it may be worthwhile to also investigate the ability of IN administration of agents such as anti ...
CLINICAL PHARMACOLOGY OF ANTIBACTERIAL AGENTS
... infectious complications of other therapeutic modalities such as cancer chemotherapy and surgery. However, evidence is overwhelming that antimicrobial agents are vastly overprescribed in outpatient settings, and the availability of antimicrobial agents without prescription in many developing countri ...
... infectious complications of other therapeutic modalities such as cancer chemotherapy and surgery. However, evidence is overwhelming that antimicrobial agents are vastly overprescribed in outpatient settings, and the availability of antimicrobial agents without prescription in many developing countri ...
Nasal fentanyl for pre-hospital pain - Quiz (click here)
... 6. Why do medications taken by mouth often come in higher dosage concentrations than medications given as a shot? a. Medications taken by mouth often are partially destroyed by the stomach acid and intestinal enzymes so more is required to achieve a therapeutic effect. b. Medications taken by mouth ...
... 6. Why do medications taken by mouth often come in higher dosage concentrations than medications given as a shot? a. Medications taken by mouth often are partially destroyed by the stomach acid and intestinal enzymes so more is required to achieve a therapeutic effect. b. Medications taken by mouth ...
A novel approach for mass production of Ag nanoparticles by using
... (DNA) as a major component (around 8% wet weight), which can be efficiently extracted. DNA has been widely studied as one of the natural polymer due to its unique structure, which causes interactions with various molecules and ions. In recent years, biopolymers have been researched as a template to ...
... (DNA) as a major component (around 8% wet weight), which can be efficiently extracted. DNA has been widely studied as one of the natural polymer due to its unique structure, which causes interactions with various molecules and ions. In recent years, biopolymers have been researched as a template to ...
raus-respiratory-care-pharmacology-8th-edition
... for useful physiologic effects. No testing has occurred before this step. Once an active chemical is isolated and identified, a series of animal studies examines its general effect on animals and effects on specific organs such as the liver or kidneys. Toxicology studies to examine mutagenicity, ter ...
... for useful physiologic effects. No testing has occurred before this step. Once an active chemical is isolated and identified, a series of animal studies examines its general effect on animals and effects on specific organs such as the liver or kidneys. Toxicology studies to examine mutagenicity, ter ...
Drugs, Dose Forms, and Delivery Systems
... segment of recombined DNA into a host cell, scientists can change what proteins the cell produces. In effect, this converts the cell into a small-scale protein factory to produce chemical substances that can be used as drugs. For example, using the bacterium Escherichia coli, microbiologists and gen ...
... segment of recombined DNA into a host cell, scientists can change what proteins the cell produces. In effect, this converts the cell into a small-scale protein factory to produce chemical substances that can be used as drugs. For example, using the bacterium Escherichia coli, microbiologists and gen ...
Basic Nursing: Foundations of Skills and Concepts Chapter 24
... Medication or Drug is a chemical substance intended for use in the diagnosis, treatment, cure, mitigation, or prevention of a disease. When a drug is given to a client, there is an intended specific effect. An assumption made by nurses before administration of any medication is that the drug wi ...
... Medication or Drug is a chemical substance intended for use in the diagnosis, treatment, cure, mitigation, or prevention of a disease. When a drug is given to a client, there is an intended specific effect. An assumption made by nurses before administration of any medication is that the drug wi ...
Nanomedicine
Nanomedicine is the medical application of nanotechnology. Nanomedicine ranges from the medical applications of nanomaterials and biological devices, to nanoelectronic biosensors, and even possible future applications of molecular nanotechnology such as biological machines. Current problems for nanomedicine involve understanding the issues related to toxicity and environmental impact of nanoscale materials (materials whose structure is on the scale of nanometers, i.e. billionths of a meter).Functionalities can be added to nanomaterials by interfacing them with biological molecules or structures. The size of nanomaterials is similar to that of most biological molecules and structures; therefore, nanomaterials can be useful for both in vivo and in vitro biomedical research and applications.Thus far, the integration of nanomaterials with biology has led to the development of diagnostic devices, contrast agents, analytical tools, physical therapy applications, and drug delivery vehicles.Nanomedicine seeks to deliver a valuable set of research tools and clinically useful devices in the near future. The National Nanotechnology Initiative expects new commercial applications in the pharmaceutical industry that may include advanced drug delivery systems, new therapies, and in vivo imaging. Nanomedicine research is receiving funding from the US National Institutes of Health, including the funding in 2005 of a five-year plan to set up four nanomedicine centers.Nanomedicine is a large industry, with nanomedicine sales reaching $6.8 billion in 2004, and with over 200 companies and 38 products worldwide, a minimum of $3.8 billion in nanotechnology R&D is being invested every year. In April 2006, the journal Nature Materials estimated that 130 nanotech-based drugs and delivery systems were being developed worldwide. As the nanomedicine industry continues to grow, it is expected to have a significant impact on the economy.