Sudden Cardiac Death in Athletes
... Commotio cordis, literally meaning “concussion of the heart,” involves a blunt, non-penetrating impact to the precordial region of the chest7. The kinetic energy of the impact is transmitted to the heart muscle and causes a fatal ventricular arrhythmia. For the impact to be fatal, it is thought that ...
... Commotio cordis, literally meaning “concussion of the heart,” involves a blunt, non-penetrating impact to the precordial region of the chest7. The kinetic energy of the impact is transmitted to the heart muscle and causes a fatal ventricular arrhythmia. For the impact to be fatal, it is thought that ...
Guidelines for the management of patients with NSTEMI ACS
... • Do not use in renal impairment (eGFR <20ml/min) – use enoxaparin 1mg/kg once daily as an alternative. • Contraindicated in active clinically significant bleeding. Caution in history of known bleeding complications. • Discontinuation of parenteral anticoagulation should be considered after PCI, unl ...
... • Do not use in renal impairment (eGFR <20ml/min) – use enoxaparin 1mg/kg once daily as an alternative. • Contraindicated in active clinically significant bleeding. Caution in history of known bleeding complications. • Discontinuation of parenteral anticoagulation should be considered after PCI, unl ...
Role of Electron Beam Computed Tomography in Detecting and
... the sensitivity of EBCT. However, the sensitivity of EBCT compares favorably with other routinely performed noninvasive studies (Table 2).41,42 To determine whether EBCT could identify patients with scintigraphic ischemia on the basis of calcium score, a group of investigators sought to correlate th ...
... the sensitivity of EBCT. However, the sensitivity of EBCT compares favorably with other routinely performed noninvasive studies (Table 2).41,42 To determine whether EBCT could identify patients with scintigraphic ischemia on the basis of calcium score, a group of investigators sought to correlate th ...
Daily Report 09-14-2016
... 48 hours ago after a late presentation with anterior ST-elevation myocardial infarction. The patient underwent coronary angiography and was found to have an occluded proximal left anterior descending coronary artery but did not undergo an attempt at revascularization at the time of coronary angiogra ...
... 48 hours ago after a late presentation with anterior ST-elevation myocardial infarction. The patient underwent coronary angiography and was found to have an occluded proximal left anterior descending coronary artery but did not undergo an attempt at revascularization at the time of coronary angiogra ...
Myocardial uptake characteristics of three 99mTc
... Objective: 99mTc-tetrofosmin and 99mTc-sestamibi are approved tracers for myocardial perfusion studies. Recently, a 99mTc-MIBI preparation from a different manufacturer (99mTc-cardiospectMIBI) has been introduced to the market. Therefore, the aim of this study was the evaluation of 99mTc-tetrofosmin ...
... Objective: 99mTc-tetrofosmin and 99mTc-sestamibi are approved tracers for myocardial perfusion studies. Recently, a 99mTc-MIBI preparation from a different manufacturer (99mTc-cardiospectMIBI) has been introduced to the market. Therefore, the aim of this study was the evaluation of 99mTc-tetrofosmin ...
ideal - Clinical Trial Results
... IDEAL Trial: Summary • Among patients with a previous myocardial infarction, treatment with high-dose atorvastatin was associated with a directional but nonsignificant reduction in the primary composite endpoint of major coronary events compared with standard dose simvastatin at five year follow-up ...
... IDEAL Trial: Summary • Among patients with a previous myocardial infarction, treatment with high-dose atorvastatin was associated with a directional but nonsignificant reduction in the primary composite endpoint of major coronary events compared with standard dose simvastatin at five year follow-up ...
Robert Kloner - Ischemic Conditioning Therapy
... patients with acute myocardial infarction: a randomised trial • 333 patients with first AMI randomized to primary PCI with or without remote conditioning (4 cycles of 5-minute brachial artery cuff inflation & 5 minutes deflation) • Median salvage index by myocardial perfusion imaging 0.75 in remote ...
... patients with acute myocardial infarction: a randomised trial • 333 patients with first AMI randomized to primary PCI with or without remote conditioning (4 cycles of 5-minute brachial artery cuff inflation & 5 minutes deflation) • Median salvage index by myocardial perfusion imaging 0.75 in remote ...
Complete Article - Journal of Morphological Science
... Figure 1. View from the left (A) and a scheme from the right (B) of the heart, in the left anterior oblique incidence (LAOI), showing the origin of the sinus node artery (SNA) that derives directly from the aorta. This artery crosses the transversal sinus of the pericardium to reach the anterior wal ...
... Figure 1. View from the left (A) and a scheme from the right (B) of the heart, in the left anterior oblique incidence (LAOI), showing the origin of the sinus node artery (SNA) that derives directly from the aorta. This artery crosses the transversal sinus of the pericardium to reach the anterior wal ...
Indezine Template
... • Troponin complex consist of I, C and T subunits, that mediates actin and myosin coupling. The troponin I and T isoforms are specific to the myocardium. • Two storage forms: cytosolic and myofibrillar. The concentration is 35X higher in the myofibril. • Therefore a marker of myocardial damagedoesn’ ...
... • Troponin complex consist of I, C and T subunits, that mediates actin and myosin coupling. The troponin I and T isoforms are specific to the myocardium. • Two storage forms: cytosolic and myofibrillar. The concentration is 35X higher in the myofibril. • Therefore a marker of myocardial damagedoesn’ ...
Myocardial infarction in an individual with Wolff-Parkinson
... examination of the heart revealed no accessory atrioventricular connection, but revealed a recent myocardial infarction. The case underlines the potential danger of the Wolff—Parkinson—White syndrome in patients with no or minimal clinical manifestations. The rapid unexpected death can be attributed ...
... examination of the heart revealed no accessory atrioventricular connection, but revealed a recent myocardial infarction. The case underlines the potential danger of the Wolff—Parkinson—White syndrome in patients with no or minimal clinical manifestations. The rapid unexpected death can be attributed ...
Association of lipoprotein-associated phospholipase A2 levels with
... angiographic CAD, and with the incidence of major adverse events. Methods and results We measured Lp-PLA2 levels in 504 consecutive patients undergoing clinically indicated coronary angiography. Mean age was 60 + 11 years and 38% were women. The mean (+SD) Lp-PLA2 level (ng/mL) was 245 + 91. Lp-PLA2 ...
... angiographic CAD, and with the incidence of major adverse events. Methods and results We measured Lp-PLA2 levels in 504 consecutive patients undergoing clinically indicated coronary angiography. Mean age was 60 + 11 years and 38% were women. The mean (+SD) Lp-PLA2 level (ng/mL) was 245 + 91. Lp-PLA2 ...
Chronic Ischemic Heart Disease
... oxygen demand. In addition, vasodilators may dilate normal coronary arteries more than diseased coronary arteries, augmenting any differences in regional perfusion of the myocardium, which can be detected by perfusion scanning. In general, vasodilator stress is preferred for myocardial perfusion ima ...
... oxygen demand. In addition, vasodilators may dilate normal coronary arteries more than diseased coronary arteries, augmenting any differences in regional perfusion of the myocardium, which can be detected by perfusion scanning. In general, vasodilator stress is preferred for myocardial perfusion ima ...
The Next Generation of Drug-Coated Balloons
... worldwide in their drug-eluting clinical program, including both large, randomized trials and investigator-initiated research on both DCBs and DESs. The Ranger SFA multicenter study is ongoing in Europe, randomizing the Ranger DCB to a standard, uncoated PTA balloon. Results from the MAJESTIC trial, ...
... worldwide in their drug-eluting clinical program, including both large, randomized trials and investigator-initiated research on both DCBs and DESs. The Ranger SFA multicenter study is ongoing in Europe, randomizing the Ranger DCB to a standard, uncoated PTA balloon. Results from the MAJESTIC trial, ...
this PDF file
... ● Slowing of the yearly rate of progression of coronary atherosclerosis in patients with and without MI, as demonstrated by intravascular ultrasound evaluation of atheroma volume.10 ● Inhibition of platelet aggregation and thromboxane synthesis.11 ● One or more of the above mechanisms may contribute ...
... ● Slowing of the yearly rate of progression of coronary atherosclerosis in patients with and without MI, as demonstrated by intravascular ultrasound evaluation of atheroma volume.10 ● Inhibition of platelet aggregation and thromboxane synthesis.11 ● One or more of the above mechanisms may contribute ...
Consensus Statement on the Utilisation of Cardiac CT
... Coronary artery disease (CAD) is characterised by the presence of atherosclerotic plaques in the coronary arteries. Coronary artery calcification is part of the development of these atherosclerotic plaques. These plaques progressively narrow the arterial lumen and hence impair blood flow. The reduct ...
... Coronary artery disease (CAD) is characterised by the presence of atherosclerotic plaques in the coronary arteries. Coronary artery calcification is part of the development of these atherosclerotic plaques. These plaques progressively narrow the arterial lumen and hence impair blood flow. The reduct ...
Right atrial dyssynchrony and atrial fibrillation after
... Introduction: Prevalence of post-coronary bypass grafting surgery (post-CABG) atrial fibrillation (AF) is high, and it’s complications are serious. Prediction of this problem and prophylactic or presumably curative managements may be helpful not only in post-CABG AF, but also in other conditions tha ...
... Introduction: Prevalence of post-coronary bypass grafting surgery (post-CABG) atrial fibrillation (AF) is high, and it’s complications are serious. Prediction of this problem and prophylactic or presumably curative managements may be helpful not only in post-CABG AF, but also in other conditions tha ...
Identification of Microvascular Obstruction Christopher M. Kramer
... demonstrated on steady state free precession cine imaging after gadolinium infusion[3]. The latter imaging strategy has been shown to correlate with findings on first pass-contrast enhanced perfusion imaging and inversion recovery gradient echo imaging[3]. These regions are generally subendocardial ...
... demonstrated on steady state free precession cine imaging after gadolinium infusion[3]. The latter imaging strategy has been shown to correlate with findings on first pass-contrast enhanced perfusion imaging and inversion recovery gradient echo imaging[3]. These regions are generally subendocardial ...
Ischaemic events and bleeding in patients undergoing
... treatment modalities, patients enrolled in such trials are carefully selected through the implementation of strict inclusion and exclusion criteria and, therefore, may not fully reflect patient populations in routine clinical practice2,3. Consequently, data from registries are an important addition ...
... treatment modalities, patients enrolled in such trials are carefully selected through the implementation of strict inclusion and exclusion criteria and, therefore, may not fully reflect patient populations in routine clinical practice2,3. Consequently, data from registries are an important addition ...
Intractable Ventricular Tachycardia Associated With Stress
... A 75-year-old woman presented with medically intractable wide QRS tachycardia. She had experienced chest discomfort during a vertebral procedure and was transferred to our hospital. Electrocardiography showed sustained wide QRS tachycardia, which persisted in various QRS axes despite the repeated ad ...
... A 75-year-old woman presented with medically intractable wide QRS tachycardia. She had experienced chest discomfort during a vertebral procedure and was transferred to our hospital. Electrocardiography showed sustained wide QRS tachycardia, which persisted in various QRS axes despite the repeated ad ...
Aortic Aneurysms - Richard Bowman MD
... with 75% occurring in the abdomen and the other 25% in the chest. Rupture of an aortic aneurysm is the 13th leading cause of death in the U.S. causing over 15,000 deaths each year. When detected early, the aorta can usually be repaired with surgery. Risk Factors for Aortic Aneurysms Abdominal aortic ...
... with 75% occurring in the abdomen and the other 25% in the chest. Rupture of an aortic aneurysm is the 13th leading cause of death in the U.S. causing over 15,000 deaths each year. When detected early, the aorta can usually be repaired with surgery. Risk Factors for Aortic Aneurysms Abdominal aortic ...
Appropriate - CCC Symposium
... To provide guidance for patients and clinicians for judicious and rational use of PCI To provide a substitute for clinical judgment Patel, M. R., et al. (2009). "ACCF/SCAI/STS/AATS/AHA/ASNC 2009 Appropriateness Criteria for Coronary Revascularization: a report by the American College of Cardiology F ...
... To provide guidance for patients and clinicians for judicious and rational use of PCI To provide a substitute for clinical judgment Patel, M. R., et al. (2009). "ACCF/SCAI/STS/AATS/AHA/ASNC 2009 Appropriateness Criteria for Coronary Revascularization: a report by the American College of Cardiology F ...
Cardiovascular Drug Delivery - Technologies, Markets and Companies Brochure
... proliferation in the adult, conversion of fibroblasts to contractile myocytes, conversion of bone marrow stem cells into cardiomyocytes, and transplantation of myocytes or other cells into injured myocardium. Advances in molecular pathophysiology of cardiovascular diseases have brought gene therapy ...
... proliferation in the adult, conversion of fibroblasts to contractile myocytes, conversion of bone marrow stem cells into cardiomyocytes, and transplantation of myocytes or other cells into injured myocardium. Advances in molecular pathophysiology of cardiovascular diseases have brought gene therapy ...
Linköping University Post Print Management of acute coronary syndromes from
... modest benefit by reducing the combined endpoint death /MI by 30 days [11.8% vs. 10.8%, OR = 0.91, 95% CI (0.84-0.98)]. Effect was mainly restricted to patients with high risk features such as elevated troponin or ST-depression. Patients undergoing PCI or CABG had greater risk reduction compared to ...
... modest benefit by reducing the combined endpoint death /MI by 30 days [11.8% vs. 10.8%, OR = 0.91, 95% CI (0.84-0.98)]. Effect was mainly restricted to patients with high risk features such as elevated troponin or ST-depression. Patients undergoing PCI or CABG had greater risk reduction compared to ...
PPT, 6.99MB
... • Infused intravenously, it reduces mortality in acute myocardial infarction, and this beneficial effect is additive with aspirin. • Its action is blocked by antibodies, which appear 4 days or more after the initial dose: its use should not be repeated after this time has elapsed. ...
... • Infused intravenously, it reduces mortality in acute myocardial infarction, and this beneficial effect is additive with aspirin. • Its action is blocked by antibodies, which appear 4 days or more after the initial dose: its use should not be repeated after this time has elapsed. ...
Drug-eluting stent
A drug-eluting stent (DES) is a peripheral or coronary stent (a scaffold) placed into narrowed, diseased peripheral or coronary arteries that slowly releases a drug to block cell proliferation. This prevents fibrosis that, together with clots (thrombi), could otherwise block the stented artery, a process called restenosis. The stent is usually placed within the peripheral or coronary artery by an interventional cardiologist or interventional radiologist during an angioplasty procedure.Drug-eluting stents in current clinical use were approved by the FDA after clinical trials showed they were statistically superior to bare-metal stents for the treatment of native coronary artery narrowings, having lower rates of major adverse cardiac events (usually defined as a composite clinical endpoint of death + myocardial infarction + repeat intervention because of restenosis). The first drug-eluting stents to be approved in Europe and the U.S. were coated with paclitaxel or an mTOR inhibitor, such as sirolimus.