The OSBP-related proteins (ORPs) - Biochemical Society Transactions
... of the ER (endoplasmic reticulum). ORP5 and ORP8 have instead a C-terminal membrane anchor that has, in the case of ORP8, been shown to specify ER targeting (D. Yan, M. Lehto and V.M. Olkkonen, unpublished work). The PH domain in the N-terminal region is in several cases known to bind membrane phosp ...
... of the ER (endoplasmic reticulum). ORP5 and ORP8 have instead a C-terminal membrane anchor that has, in the case of ORP8, been shown to specify ER targeting (D. Yan, M. Lehto and V.M. Olkkonen, unpublished work). The PH domain in the N-terminal region is in several cases known to bind membrane phosp ...
NAC Protein Family
... • Def: Stem-cell tissue at the tip of the shoot or root that divides, and is responsible for increasing the plant’s length. Shoot AM --> Root AM --> ...
... • Def: Stem-cell tissue at the tip of the shoot or root that divides, and is responsible for increasing the plant’s length. Shoot AM --> Root AM --> ...
Gene Normalization - Computational Bioscience Program
... sites on proteins with literature-based validation ...
... sites on proteins with literature-based validation ...
Dreissena
... The zebra mussel (Dreissena polymorpha) and quagga mussel (Dreissena bugensis) are changing the Great Lakes ecosystem and surrounding fresh waters. They alter ecosystems through their voracious filter feeding ability that removes algae, bacteria, and protozoa from the water column which disrupts the ...
... The zebra mussel (Dreissena polymorpha) and quagga mussel (Dreissena bugensis) are changing the Great Lakes ecosystem and surrounding fresh waters. They alter ecosystems through their voracious filter feeding ability that removes algae, bacteria, and protozoa from the water column which disrupts the ...
Straying off the Highway: Trafficking of Secreted
... interaction, to covalently bound. In addition, when cell walls extracts are prepared, by tissue or cell homogenization followed by centrifugation, substantial amounts of intracellular protein inevitably associate with the wall pellet, while proteins and peptides that were not bound to the wall in vi ...
... interaction, to covalently bound. In addition, when cell walls extracts are prepared, by tissue or cell homogenization followed by centrifugation, substantial amounts of intracellular protein inevitably associate with the wall pellet, while proteins and peptides that were not bound to the wall in vi ...
Gene Ontology (GO)
... because the same amino acid features are important to both. For instance, hydrophobicity is a main component in both mutation matrices and some interaction parameter sets. •Some similarities between methods also occur when potential energy parameters contain a strong "sequence memory" by including c ...
... because the same amino acid features are important to both. For instance, hydrophobicity is a main component in both mutation matrices and some interaction parameter sets. •Some similarities between methods also occur when potential energy parameters contain a strong "sequence memory" by including c ...
Protein microarrays
... gene products by large-scale genomic and proteomic initiatives has required the development of high-throughput strategies to elucidate their function [8]. There have primarily been two approaches to characterize multiple proteins in biological samples. The first approach, 2D-gels, has been widely us ...
... gene products by large-scale genomic and proteomic initiatives has required the development of high-throughput strategies to elucidate their function [8]. There have primarily been two approaches to characterize multiple proteins in biological samples. The first approach, 2D-gels, has been widely us ...
Final Presentations Abstract Book(1.3 Mb .pdb file)
... diseases are caused by members of the viral family Picornaviridae. The common cold is the most prevalent infectious disease in humans and results in major economic impact through loss of productivity and strain on healthcare systems. 3A is a membrane protein produced by these viruses that is necessa ...
... diseases are caused by members of the viral family Picornaviridae. The common cold is the most prevalent infectious disease in humans and results in major economic impact through loss of productivity and strain on healthcare systems. 3A is a membrane protein produced by these viruses that is necessa ...
Protein folding
... polypeptide to end (before the stop codon) 2. make RNA using nucleotides and polymerase enzyme 3. add to an in vitro translation system (rabbit reticulocyte lysate), which has all of the required components to translate the RNA 4. if the RNA is not truncated, the full-length protein will be made and ...
... polypeptide to end (before the stop codon) 2. make RNA using nucleotides and polymerase enzyme 3. add to an in vitro translation system (rabbit reticulocyte lysate), which has all of the required components to translate the RNA 4. if the RNA is not truncated, the full-length protein will be made and ...
AXL_Instruction
... Background Information The protein encoded by this gene is a member of the Tyro3-Axl-Mer (TAM) receptor tyrosine kinase subfamily. The encoded protein possesses an extracellular domain which is composed of two immunoglobulin-like motifs at the N-terminal, followed by two fibronectin type-III motifs. ...
... Background Information The protein encoded by this gene is a member of the Tyro3-Axl-Mer (TAM) receptor tyrosine kinase subfamily. The encoded protein possesses an extracellular domain which is composed of two immunoglobulin-like motifs at the N-terminal, followed by two fibronectin type-III motifs. ...
Read more... - Barrhaven Business Improvement Area
... protocol supervised by a health professional. “Patients will come in and meet for an initial consultation, and then we will meet once a week after that,” said Little. “There are two components to the program structured around four distinct phases. There is a weight loss phase, and then a maintenance ...
... protocol supervised by a health professional. “Patients will come in and meet for an initial consultation, and then we will meet once a week after that,” said Little. “There are two components to the program structured around four distinct phases. There is a weight loss phase, and then a maintenance ...
Functions and inhibitors of SecA, an essential protein in bacterial
... across cytoplasmic membranes. In addition to the high-affinity SecA-SecYEG-SecDF•YajC protein-conducting channels, we have found that there are low-affinity SecA-only channels that elicit ion channel activity and promote protein translocation. These pore channels are less efficient, and like Prl sup ...
... across cytoplasmic membranes. In addition to the high-affinity SecA-SecYEG-SecDF•YajC protein-conducting channels, we have found that there are low-affinity SecA-only channels that elicit ion channel activity and promote protein translocation. These pore channels are less efficient, and like Prl sup ...
Assignment 02 Computational Proteomics and Metabolomics
... (c) isoelectric point (pI): Consider the peptide EVEDLQVR. Show that the theoretical pI value is between 4 and 4.5 . Use the programs ’ProtParam’ and ’Compute pI/Mw’ from the expasy website to verify this. (d) m/z ratio: In a spectrogram there are two peaks at m/z values 239 and 358. Examine if thes ...
... (c) isoelectric point (pI): Consider the peptide EVEDLQVR. Show that the theoretical pI value is between 4 and 4.5 . Use the programs ’ProtParam’ and ’Compute pI/Mw’ from the expasy website to verify this. (d) m/z ratio: In a spectrogram there are two peaks at m/z values 239 and 358. Examine if thes ...
Datasheet for Protein Marker, Broad Range (2-212 kDa)
... Contents: 0.1–0.2 mg/ml of each protein in 70 mM Tris-HCl (pH 6.8 @ 25°C), 33 mM NaCl, 1 mM Na2EDTA, 2% (w/v) SDS, 40 mM DTT, 0.01% (w/v) bromophenol blue and 10% glycerol. ...
... Contents: 0.1–0.2 mg/ml of each protein in 70 mM Tris-HCl (pH 6.8 @ 25°C), 33 mM NaCl, 1 mM Na2EDTA, 2% (w/v) SDS, 40 mM DTT, 0.01% (w/v) bromophenol blue and 10% glycerol. ...
Asp P
... cholera (a facultative aerobe) binds NO in a high spin 5-coordinate complex and excludes oxygen, while the H-NOX domain from Thermoanaerobacter tengcongensis (Tt, obligate anaerobe) has been found to bind oxygen in a low-spin 6-coordinate complex, making it the first member of the family to bind O2. ...
... cholera (a facultative aerobe) binds NO in a high spin 5-coordinate complex and excludes oxygen, while the H-NOX domain from Thermoanaerobacter tengcongensis (Tt, obligate anaerobe) has been found to bind oxygen in a low-spin 6-coordinate complex, making it the first member of the family to bind O2. ...
Model Design Parameters
... determined the important features of the protein that you wish to display in the model. As you are reading background papers, you should make a list of important interactions you might consider displaying on your model. Here’s a list of some of the features that may be useful to display in your mode ...
... determined the important features of the protein that you wish to display in the model. As you are reading background papers, you should make a list of important interactions you might consider displaying on your model. Here’s a list of some of the features that may be useful to display in your mode ...
Coevolution analysis of viral sequences: from HBV - LCQB
... 2. The computational identification of the residues being involved in HBV membrane fusion. We shall extend the use of our coevolution analysis tool (see Objective 1), to predict intra- and inter-protein interactions underlying the HBV entry process, including the binding and membrane fusio ...
... 2. The computational identification of the residues being involved in HBV membrane fusion. We shall extend the use of our coevolution analysis tool (see Objective 1), to predict intra- and inter-protein interactions underlying the HBV entry process, including the binding and membrane fusio ...
A Ran-binding protein, RanBPM, stabilizes p73 and enhances its
... important regulator in inducing programmed cell death of sympathetic neurons. Like p53, p73 inhibits cell cycle progression and/or stimulates apoptosis, which is in large part due to its transactivation ability. Previously, we and others demonstrated that the extreme COOH-terminal region of p73alpha ...
... important regulator in inducing programmed cell death of sympathetic neurons. Like p53, p73 inhibits cell cycle progression and/or stimulates apoptosis, which is in large part due to its transactivation ability. Previously, we and others demonstrated that the extreme COOH-terminal region of p73alpha ...
(PUNCH-P) reveals cell cycle
... Monitoring protein synthesis is essential to our understanding of gene expression regulation, as protein abundance is thought to be predominantly controlled at the level of translation. Mass-spectrometric and RNA sequencing methods have been recently developed for investigating mRNA translation at a ...
... Monitoring protein synthesis is essential to our understanding of gene expression regulation, as protein abundance is thought to be predominantly controlled at the level of translation. Mass-spectrometric and RNA sequencing methods have been recently developed for investigating mRNA translation at a ...
Structure of Proteins
... 9. The process is repeated many times , thus translating the mRNA into a complete polypeptide chain. 10.When a stop codon is reached the site A on the ribosome releases the polypeptide. This whole process needs energy from ATP. ...
... 9. The process is repeated many times , thus translating the mRNA into a complete polypeptide chain. 10.When a stop codon is reached the site A on the ribosome releases the polypeptide. This whole process needs energy from ATP. ...
Amino Acids
... • X-ray crystallography and IR spectroscopy demonstrate a characteristic β-pleated sheet conformation in nonbranching fibrils • This peptide, when aggregated in β-pleated sheet configuration, is neurotoxic, is central pathogenic event cognitive impairment characteristic of disease • Aβ amyloid dep ...
... • X-ray crystallography and IR spectroscopy demonstrate a characteristic β-pleated sheet conformation in nonbranching fibrils • This peptide, when aggregated in β-pleated sheet configuration, is neurotoxic, is central pathogenic event cognitive impairment characteristic of disease • Aβ amyloid dep ...
Presentación de PowerPoint - International Potato Center
... The evolutionary history was inferred using the Neighbor-Joining method [2]. The bootstrap consensus tree inferred from 1000 replicates [3] is taken to represent the evolutionary history of the taxa analyzed [3]. Branches corresponding to partitions reproduced in less than 50% bootstrap replicates a ...
... The evolutionary history was inferred using the Neighbor-Joining method [2]. The bootstrap consensus tree inferred from 1000 replicates [3] is taken to represent the evolutionary history of the taxa analyzed [3]. Branches corresponding to partitions reproduced in less than 50% bootstrap replicates a ...
Proteomics
Proteomics is the large-scale study of proteins, particularly their structures and functions. Proteins are vital parts of living organisms, as they are the main components of the physiological metabolic pathways of cells. The term proteomics was first coined in 1997 to make an analogy with genomics, the study of the genome. The word proteome is a portmanteau of protein and genome, and was coined by Marc Wilkins in 1994 while working on the concept as a PhD student.The proteome is the entire set of proteins, produced or modified by an organism or system. This varies with time and distinct requirements, or stresses, that a cell or organism undergoes. Proteomics is an interdisciplinary domain formed on the basis of the research and development of the Human Genome Project; it is also emerging scientific research and exploration of proteomes from the overall level of intracellular protein composition, structure, and its own unique activity patterns. It is an important component of functional genomics.While proteomics generally refers to the large-scale experimental analysis of proteins, it is often specifically used for protein purification and mass spectrometry.