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Some Like it Cool
Some Like it Cool

... Some like it cool – THz absorption studies of as a tool to study biomolecular hydration Martina Havenith Ruhr-Universität Bochum ...
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Slide 1

... What molecule contains the master instructions for genetic traits & where is it found? What molecule does DNA actually code for the production of? Why do we care about proteins? Where are proteins made? What are they made of? TRAITS!!! How does DNA send the ‘message’ to the ribosomes to make protein ...
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biological process

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Brief overview of Bio backgound

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Protein–protein interaction



Protein–protein interactions (PPIs) refer to physical contacts established between two or more proteins as a result of biochemical events and/or electrostatic forces.In fact, proteins are vital macromolecules, at both cellular and systemic levels, but they rarely act alone. Diverse essential molecular processes within a cell are carried out by molecular machines that are built from a large number of protein components organized by their PPIs. Indeed, these interactions are at the core of the entire interactomics system of any living cell and so, unsurprisingly, aberrant PPIs are on the basis of multiple diseases, such as Creutzfeld-Jacob, Alzheimer's disease, and cancer.PPIs have been studied from different perspectives: biochemistry, quantum chemistry, molecular dynamics, signal transduction, among others. All this information enables the creation of large protein interaction networks – similar to metabolic or genetic/epigenetic networks – that empower the current knowledge on biochemical cascades and disease pathogenesis, as well as provide putative new therapeutic targets.
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