ARGONAUTE1 Acts in Arabidopsis Root Radial
... genomes. In Arabidopsis, initial cloning experiments identified 19 miRNAs which fell into 15 families (Llave et al. 2002a, Mette et al. 2002, Park et al. 2002, Reinhart et al. 2002). Largescale sequencing approaches have revealed numerous miRNAs and their target genes (Rajagopalan et al. 2006, Fahlgr ...
... genomes. In Arabidopsis, initial cloning experiments identified 19 miRNAs which fell into 15 families (Llave et al. 2002a, Mette et al. 2002, Park et al. 2002, Reinhart et al. 2002). Largescale sequencing approaches have revealed numerous miRNAs and their target genes (Rajagopalan et al. 2006, Fahlgr ...
Caspary T, Cleary MA, Perlman EJ, Zhang P, Elledge SJ, and Tilghman SM. Genes Dev. 1999 Dec 1;13(23):3115-24. Oppositely imprinted genes p57Kip2 and Igf2 interact in a mouse model for Beckwith-Wiedemann syndrome.
... Beckwith–Wiedemann syndrome (BWS) is a clinically variable disorder characterized by somatic overgrowth, macroglossia, abdominal wall defects, visceromegaly, and an increased susceptibility to childhood tumors. The disease has been linked to a large cluster of imprinted genes at human chromosome 11p ...
... Beckwith–Wiedemann syndrome (BWS) is a clinically variable disorder characterized by somatic overgrowth, macroglossia, abdominal wall defects, visceromegaly, and an increased susceptibility to childhood tumors. The disease has been linked to a large cluster of imprinted genes at human chromosome 11p ...
Twin methodology in epigenetic studies
... phenotypes including molecular phenotypes such as gene expression activity and DNA methylation levels. DZ twin pairs are in fact ordinary siblings. By estimating phenotype-dependent allele-sharing identical-by-descent (IBD) within a pair, the non-parametric linkage analysis can be performed using va ...
... phenotypes including molecular phenotypes such as gene expression activity and DNA methylation levels. DZ twin pairs are in fact ordinary siblings. By estimating phenotype-dependent allele-sharing identical-by-descent (IBD) within a pair, the non-parametric linkage analysis can be performed using va ...
Point mutation of bacterial artificial chromosomes by ET recombination
... Sternberg, 1992; Ioannou et al., 1994), offer great potential for these studies, because in most cases all of the regulatory regions of the gene can be included. Thus, these large constructs provide an environment in which the native expression pattern is preserved, without the need to identify all ...
... Sternberg, 1992; Ioannou et al., 1994), offer great potential for these studies, because in most cases all of the regulatory regions of the gene can be included. Thus, these large constructs provide an environment in which the native expression pattern is preserved, without the need to identify all ...
Hybrid Plasmids Containing the Pyruvate
... Enzymology. The specific activities of the pyruvate dehydrogenase complex, its three components and the 2-oxoglutarate complex were assayed in ultrasonic extracts of the conjugants grown in glucose-based minimal media and L broth plus glucose (Table 2). The results confirmed that one plasmid, pGS2, ...
... Enzymology. The specific activities of the pyruvate dehydrogenase complex, its three components and the 2-oxoglutarate complex were assayed in ultrasonic extracts of the conjugants grown in glucose-based minimal media and L broth plus glucose (Table 2). The results confirmed that one plasmid, pGS2, ...
DnaJ-related protein essential for placentation - Development
... in only a portion of mutant conceptuses indicating that the VCAM1/α4 integrin interaction is not the only mechanism mediating chorioallantoic fusion. FGF signaling also plays a role in placental development since a hypomorphic mutation in the FGFR2 gene causes either defects in chorioallantoic fusio ...
... in only a portion of mutant conceptuses indicating that the VCAM1/α4 integrin interaction is not the only mechanism mediating chorioallantoic fusion. FGF signaling also plays a role in placental development since a hypomorphic mutation in the FGFR2 gene causes either defects in chorioallantoic fusio ...
MicroRNA-mediated regulation of flower development in grasses
... develop bract-like structures – palea and lemma. Reproductive organs are enclosed by round lodicule that not only protects reproductive organs but also plays an important role during flower opening. The first genetic model for floral organ development was proposed 25 years ago and it was based on th ...
... develop bract-like structures – palea and lemma. Reproductive organs are enclosed by round lodicule that not only protects reproductive organs but also plays an important role during flower opening. The first genetic model for floral organ development was proposed 25 years ago and it was based on th ...
Coexpression of Linked Genes in Mammalian
... of linked yeast genes (Lercher and Hurst 2006), the adaptive model implies that the gene order in the yeast genome must be highly organized. However, the high plasticity of yeast gene order revealed from a comparison of 11 species (Fischer et al. 2006) argues against this view. In addition, it is we ...
... of linked yeast genes (Lercher and Hurst 2006), the adaptive model implies that the gene order in the yeast genome must be highly organized. However, the high plasticity of yeast gene order revealed from a comparison of 11 species (Fischer et al. 2006) argues against this view. In addition, it is we ...
Pole Region-Dependent Repression of the Drosophila Gap Gene
... genes acting at the poles. The formation of the Kf protein domain may involve ubiquitous activation of Kr gene expression which, however, is limited by regionspecific repression through the action of the maternal anterior and posterior pattern organizer genes. In addition, the formation of the Kr pr ...
... genes acting at the poles. The formation of the Kf protein domain may involve ubiquitous activation of Kr gene expression which, however, is limited by regionspecific repression through the action of the maternal anterior and posterior pattern organizer genes. In addition, the formation of the Kr pr ...
Microcalorimetry of biological macromolecules
... the heat capacity of the native and unfolded states of the protein over the whole considered temperature range. In the first calorimetric experiments, when the precision of the calorimetric measurements was not high, it was assumed that the difference between the heat capacity of the native and unfo ...
... the heat capacity of the native and unfolded states of the protein over the whole considered temperature range. In the first calorimetric experiments, when the precision of the calorimetric measurements was not high, it was assumed that the difference between the heat capacity of the native and unfo ...
The Schistosoma gene discovery program: state of the art
... Fig. 1. The success of the Schistosoma Gene Discovery Program. Number of S. mansoni (A) and S. japonicum (B) ESTs and genes deposited in databases from 1993 to 1999. ...
... Fig. 1. The success of the Schistosoma Gene Discovery Program. Number of S. mansoni (A) and S. japonicum (B) ESTs and genes deposited in databases from 1993 to 1999. ...
Abnormal anaphase resolution - Journal of Cell Science
... these mitotic domains. The zygotic expression of cyclin A (Lehner and O’Farrell, 1989) and string (Edgar and O’Farrell, 1989; Jimenez et al., 1990), is required to regulate the length of G2 phase within these newly cellularized embryonic cells (Edgar and O’Farrell, 1990), whereas zygotic expression ...
... these mitotic domains. The zygotic expression of cyclin A (Lehner and O’Farrell, 1989) and string (Edgar and O’Farrell, 1989; Jimenez et al., 1990), is required to regulate the length of G2 phase within these newly cellularized embryonic cells (Edgar and O’Farrell, 1990), whereas zygotic expression ...
The trp Operon
... the flexible neck straw. Smooth the tape down as much as possible. Each colored straw segment represents a gene. Collectively, the structure formed when the pieces are taped to the longer straw now represents the trp operon. d. The RNA polymerase is represented by the segment of straw with the large ...
... the flexible neck straw. Smooth the tape down as much as possible. Each colored straw segment represents a gene. Collectively, the structure formed when the pieces are taped to the longer straw now represents the trp operon. d. The RNA polymerase is represented by the segment of straw with the large ...
Screen Guidelines
... other hand, it is not possible to tell how many siRNAs from a given pool generate a particular phenotype, which may increase the number of false-positives or false negatives. Typically, putative hits from pooled siRNA screens are evaluated by testing each siRNA alone. If an identical phenotype is ob ...
... other hand, it is not possible to tell how many siRNAs from a given pool generate a particular phenotype, which may increase the number of false-positives or false negatives. Typically, putative hits from pooled siRNA screens are evaluated by testing each siRNA alone. If an identical phenotype is ob ...
A xylem-specific cellulose synthase gene from aspen (Populus
... plants were bent to create tension stress for various time intervals (from 4 to 40 h). Surprisingly, tension stress rapidly induced phloem-speci®c GUS expression (Figure 5), but did not cause an apparent change in GUS expression in the developing xylem (Figure 5b). Thus under a normal developmental ...
... plants were bent to create tension stress for various time intervals (from 4 to 40 h). Surprisingly, tension stress rapidly induced phloem-speci®c GUS expression (Figure 5), but did not cause an apparent change in GUS expression in the developing xylem (Figure 5b). Thus under a normal developmental ...
Life: The Science of Biology, 8e
... The Genetics of Viruses and Prokaryotes - How do prokaryotes exchange genes? Transposable elements and transposons ...
... The Genetics of Viruses and Prokaryotes - How do prokaryotes exchange genes? Transposable elements and transposons ...
The Neurospora crassa colonial temperature
... On the other hand, even though reduced calcineurin activity has already been shown to affect hyphal polarity in N. crassa and A. nidulans, no significant effect on hyphal growth of C. albicans was observed (Bader et al. 2003), despite the protein having a clear effect on pathogenicity. Calcineurin w ...
... On the other hand, even though reduced calcineurin activity has already been shown to affect hyphal polarity in N. crassa and A. nidulans, no significant effect on hyphal growth of C. albicans was observed (Bader et al. 2003), despite the protein having a clear effect on pathogenicity. Calcineurin w ...
University of Groningen The evolution of bacterial cell differentiation
... The dense aggregation of cells on a surface, as seen in bio"ilms, inevitably results in both environmental and cellular heterogeneity. For example, nutrient gradients can trigger cells to differentiate into various phenotypic states. Not only do cells adapt physiologically to the local environmental ...
... The dense aggregation of cells on a surface, as seen in bio"ilms, inevitably results in both environmental and cellular heterogeneity. For example, nutrient gradients can trigger cells to differentiate into various phenotypic states. Not only do cells adapt physiologically to the local environmental ...
Risk Factors For Cancer
... • Some DNA mutations are the result of environmental exposures. – These exposures may include substances, such as the chemicals in tobacco smoke, or radiation, such as ultraviolet rays from the sun. – It may be harder to avoid others, such as the air we breathe, the water we drink, the food we eat, ...
... • Some DNA mutations are the result of environmental exposures. – These exposures may include substances, such as the chemicals in tobacco smoke, or radiation, such as ultraviolet rays from the sun. – It may be harder to avoid others, such as the air we breathe, the water we drink, the food we eat, ...
Ribosomal Protein RPL27a Promotes Female
... were indistinguishable from the wild type, and the number of defective ovules in siliques was not significantly different from the wild type (Fig. 2C). Homozygous rpl27ab-1 and rpl27ab-2 mutants were not noticeably different from the wild type, except siliques showed 14.4% and 11.3% defective ovules, ...
... were indistinguishable from the wild type, and the number of defective ovules in siliques was not significantly different from the wild type (Fig. 2C). Homozygous rpl27ab-1 and rpl27ab-2 mutants were not noticeably different from the wild type, except siliques showed 14.4% and 11.3% defective ovules, ...
Positional dependence of transcriptional inhibition by DNA torsional
... relative to the large RNA polymerase complex. This rotation is quickly hindered by nearby interactions that anchor DNA to other structures or, simply, by the large rotational drag of DNA folded in chromatin. Consequently, positive ( þ ) DNA helical tension increases in front of an advancing polymera ...
... relative to the large RNA polymerase complex. This rotation is quickly hindered by nearby interactions that anchor DNA to other structures or, simply, by the large rotational drag of DNA folded in chromatin. Consequently, positive ( þ ) DNA helical tension increases in front of an advancing polymera ...
Molecular characterization of dioxygenases from polycyclic aromatic
... component and contains two conserved regions : the [Fe2 ^S2 ] Rieske center and the mononuclear iron binding domain, which are involved in the consecutive electron transfer to the dioxygen molecule [6]. Both K and L subunits are necessary for function and in determining the substrate speci¢city of t ...
... component and contains two conserved regions : the [Fe2 ^S2 ] Rieske center and the mononuclear iron binding domain, which are involved in the consecutive electron transfer to the dioxygen molecule [6]. Both K and L subunits are necessary for function and in determining the substrate speci¢city of t ...
Chapter 10 and 13
... micropenis; B3, slight micropenis; and uncle, micropenis and penoscrotal hypospadias. All had been assigned a male gender. We detected the same L712F mutation of the androgen receptor (AR) gene in each subject. Methyltrienolone binding on cultured genital skin fibroblasts of B2 suggested moderate im ...
... micropenis; B3, slight micropenis; and uncle, micropenis and penoscrotal hypospadias. All had been assigned a male gender. We detected the same L712F mutation of the androgen receptor (AR) gene in each subject. Methyltrienolone binding on cultured genital skin fibroblasts of B2 suggested moderate im ...