Genetics of Asthma – Paul E. Moore MD
... Chronic inflammation Airway reactivity to specific triggers Reversible airway obstruction Manifest as symptoms that can include cough, wheeze, and dyspnea ...
... Chronic inflammation Airway reactivity to specific triggers Reversible airway obstruction Manifest as symptoms that can include cough, wheeze, and dyspnea ...
Drosophila melanogaster
... The first instar evolves after the first molting after the hatch of the egg where the mouth parts have also shed. They are about 1 mm in length. The second instar is twice as long as the first instar (2 mm). It appears after the molting of the first instar. The increase in length is merely due to th ...
... The first instar evolves after the first molting after the hatch of the egg where the mouth parts have also shed. They are about 1 mm in length. The second instar is twice as long as the first instar (2 mm). It appears after the molting of the first instar. The increase in length is merely due to th ...
A novel C. elegans zinc finger transcription factor, lsy
... Monod and Jacob proposed more than 40 years ago that the terminal differentiated state of a cell in a multicellular organism is determined and stabilized by feedback loops composed of gene regulatory factors (Monod and Jacob, 1961). The autoregulation of transcription factors has now indeed been rec ...
... Monod and Jacob proposed more than 40 years ago that the terminal differentiated state of a cell in a multicellular organism is determined and stabilized by feedback loops composed of gene regulatory factors (Monod and Jacob, 1961). The autoregulation of transcription factors has now indeed been rec ...
Mark Scheme - Unit F215 - Control, genomes and
... FA in guidance column means: Mark the first answer. If the answer is correct and an additional answer is given that is incorrect or contradicts the correct answer then = 0 marks. Apply the same reasoning where the instruction is to mark the first 2 suggestions. ACCEPT incorrect spellings if they are ...
... FA in guidance column means: Mark the first answer. If the answer is correct and an additional answer is given that is incorrect or contradicts the correct answer then = 0 marks. Apply the same reasoning where the instruction is to mark the first 2 suggestions. ACCEPT incorrect spellings if they are ...
Student Accomplishments for 2005 – 2006
... Jordan Kaplan (Senior) Mentor: Dr. Amanda Norvell Development of a genetic screen in Drosophila melanogaster for identifying new genes which are required for the production of correctly formed eggs Anjali Mone (Sophomore) Genes subject to translational control during zebrafish embryogenesis ...
... Jordan Kaplan (Senior) Mentor: Dr. Amanda Norvell Development of a genetic screen in Drosophila melanogaster for identifying new genes which are required for the production of correctly formed eggs Anjali Mone (Sophomore) Genes subject to translational control during zebrafish embryogenesis ...
Fig 16.12a - McGraw Hill Higher Education
... • Each regulatory region can have dozens of enhancers Enhanceosome – multimeric complex of proteins and other small molecules that associate with an enhancer • Enhancers can be bound by activators and repressors with varying affinities • Different sets of cofactors and corepressors compete for bindi ...
... • Each regulatory region can have dozens of enhancers Enhanceosome – multimeric complex of proteins and other small molecules that associate with an enhancer • Enhancers can be bound by activators and repressors with varying affinities • Different sets of cofactors and corepressors compete for bindi ...
1 Heterogeneous lineage marker expression in naive
... We are interested in the case where kA > kB since experimentally recovery from (-) is always slower than from (+). The requirement that all k be nonnegative therefore implies that g < 1/↵⇤ , so the range of possible values is 0 g < 1/↵⇤ . Calculated recovery curves are shown in Fig. S13. In the pl ...
... We are interested in the case where kA > kB since experimentally recovery from (-) is always slower than from (+). The requirement that all k be nonnegative therefore implies that g < 1/↵⇤ , so the range of possible values is 0 g < 1/↵⇤ . Calculated recovery curves are shown in Fig. S13. In the pl ...
Increased transversions in a novel mutator colon cancer cell line
... expected, when Vaco411 extracts are challenged with insertion-deletion heteroduplex substrates consisting of either a 5' T loop, a 5' CA loop, or a 3' CA loop, they repair these insertion ± deletion heteroduplex substrates as well as the control SO cell line. Vaco411 mutations lack frameshifts Consi ...
... expected, when Vaco411 extracts are challenged with insertion-deletion heteroduplex substrates consisting of either a 5' T loop, a 5' CA loop, or a 3' CA loop, they repair these insertion ± deletion heteroduplex substrates as well as the control SO cell line. Vaco411 mutations lack frameshifts Consi ...
The Plant Cell
... 2002). Plant miRNAs thus are likely to control developmental decisions by downregulating important developmental transcription factors. To date, however, there are limited data directly demonstrating a role for miRNAs in plant development. Llave et al. (2002b) have shown that a transcript for a SCAR ...
... 2002). Plant miRNAs thus are likely to control developmental decisions by downregulating important developmental transcription factors. To date, however, there are limited data directly demonstrating a role for miRNAs in plant development. Llave et al. (2002b) have shown that a transcript for a SCAR ...
View PDF - Faculty Web Sites at the University of Virginia
... motors have been linked only in general terms to particular in lliz)o functions. Nevertheless, it is not too early to speculate that the cell makes use of numerous microtubule motors, each of which normally specializes in particular tasks, but may overlap functionally with other motor proteins. This ...
... motors have been linked only in general terms to particular in lliz)o functions. Nevertheless, it is not too early to speculate that the cell makes use of numerous microtubule motors, each of which normally specializes in particular tasks, but may overlap functionally with other motor proteins. This ...
VistaSeq Hereditary Cancer Panel
... 6. Ratajska, M et al., Cancer predisposing BARD1 mutations in breast-ovarian cancer families. Breast Cancer Res Treat 2012; 131:89-97. 7. Garber, J and Offit, K, Hereditary Cancer Predisposition Syndromes. J Clin Oncol 2005; 23:276-92. 8. Rafner, T et al., Mutations in BRIP1 confer high ris ...
... 6. Ratajska, M et al., Cancer predisposing BARD1 mutations in breast-ovarian cancer families. Breast Cancer Res Treat 2012; 131:89-97. 7. Garber, J and Offit, K, Hereditary Cancer Predisposition Syndromes. J Clin Oncol 2005; 23:276-92. 8. Rafner, T et al., Mutations in BRIP1 confer high ris ...
A nested deletion approach to generate Cre deleter mice with
... Mouse genetics disposes of a set of technologies, which have made this animal a valuable model for human development, physiology and diseases. Of particular interest is the loxP/Cre recombinase system, which allows for site- or time-specific recombination of particular target sequences, hence for a ...
... Mouse genetics disposes of a set of technologies, which have made this animal a valuable model for human development, physiology and diseases. Of particular interest is the loxP/Cre recombinase system, which allows for site- or time-specific recombination of particular target sequences, hence for a ...
Considerations for Analyzing Targeted NGS Data – HLA
... High degree of heterozygosity – homozygotes are the exception in this region. ...
... High degree of heterozygosity – homozygotes are the exception in this region. ...
Chromatin Evolution and Molecular Drive in Speciation
... Population genetics studies have indicated that positive selection is operating in seven nucleoporin genes, including Nup160 and Nup96 [79, 80, 83] and have revealed significant correlated evolution between them [84]. Several hypotheses have been proposed for why nucleoporins are evolving so rapidly ...
... Population genetics studies have indicated that positive selection is operating in seven nucleoporin genes, including Nup160 and Nup96 [79, 80, 83] and have revealed significant correlated evolution between them [84]. Several hypotheses have been proposed for why nucleoporins are evolving so rapidly ...
Endocytobiosis and Cell Research
... Bradyrhizobium japonicum and Sinorhizobium fredii are sensitive towards the phytoalexin glyceollin. The antibacterial effect of the soybean phytoalexin glyceollin was assayed using a liquid microculture technique (Parniske et al., 1991). Log-phase cells of Bradyrhizobium japonicum and Sinorhizobium ...
... Bradyrhizobium japonicum and Sinorhizobium fredii are sensitive towards the phytoalexin glyceollin. The antibacterial effect of the soybean phytoalexin glyceollin was assayed using a liquid microculture technique (Parniske et al., 1991). Log-phase cells of Bradyrhizobium japonicum and Sinorhizobium ...
Chapter 21
... Each family of transposons in maize has both autonomous and nonautonomous controlling elements. Autonomous controlling elements code for proteins that enable them to transpose. Nonautonomous controlling elements have mutations that eliminate their capacity to catalyze transposition, but they can tra ...
... Each family of transposons in maize has both autonomous and nonautonomous controlling elements. Autonomous controlling elements code for proteins that enable them to transpose. Nonautonomous controlling elements have mutations that eliminate their capacity to catalyze transposition, but they can tra ...
Dragon Genetics
... For the Law of Independent Assortment activity, each student will need two popsicle sticks, representing the two pairs of homologous chromosomes for the mother. One popsicle stick will have a W on one side of the popsicle stick and a w on the other side, representing the heterozygous wing genes. The ...
... For the Law of Independent Assortment activity, each student will need two popsicle sticks, representing the two pairs of homologous chromosomes for the mother. One popsicle stick will have a W on one side of the popsicle stick and a w on the other side, representing the heterozygous wing genes. The ...
Gene Section SRSF1 (serine/arginine rich splicing factor 1) -
... SF2/ASF modulates both constitutive and alternative pre-mRNA splicing. The function of SF2/ASF in splicing depends on the pre-mRNA sequence and the cellular context. Cis-acting sequences and trans-acting factors modulate SF2/ASF activity. For example, SF2/ASF antagonizes the activity of hnRNP A/B pr ...
... SF2/ASF modulates both constitutive and alternative pre-mRNA splicing. The function of SF2/ASF in splicing depends on the pre-mRNA sequence and the cellular context. Cis-acting sequences and trans-acting factors modulate SF2/ASF activity. For example, SF2/ASF antagonizes the activity of hnRNP A/B pr ...
Experimental procedures (detailed)
... gamete-related cells or organs, local tBLASTx searches were performed with a cut-off value of 1.0×e-10. ...
... gamete-related cells or organs, local tBLASTx searches were performed with a cut-off value of 1.0×e-10. ...
Oncogenic potential of the DNA replication licensing protein
... Cells overexpressing Ris2/Cdt1 exhibited a quicker entry into S phase when released from serum starvation compared to controls. Our results suggest that CDT1, an essential licensing protein for DNA replication, can function as an oncogene in mammals. Oncogene (2002) 21, 1150 ± 1158. DOI: 10.1038/sj/ ...
... Cells overexpressing Ris2/Cdt1 exhibited a quicker entry into S phase when released from serum starvation compared to controls. Our results suggest that CDT1, an essential licensing protein for DNA replication, can function as an oncogene in mammals. Oncogene (2002) 21, 1150 ± 1158. DOI: 10.1038/sj/ ...
Epigenetic changes in the estrogen receptor α gene
... Androgen does not affect the brain directly; instead masculinization is largely mediated by estradiol converted from testosterone by aromatase in the brain. The presence or absence of brief exposure to estradiol during the perinatal period creates permanent sex differences in the brain including las ...
... Androgen does not affect the brain directly; instead masculinization is largely mediated by estradiol converted from testosterone by aromatase in the brain. The presence or absence of brief exposure to estradiol during the perinatal period creates permanent sex differences in the brain including las ...
Microarrays - Consortium for Mathematics and its Applications
... border with the pigment spreading into to surrounding skin. Its coloration is varied with some parts being red, some tan and some black. You tell Ralph that you are concerned that this mole may have developed into melanoma, a type of skin cancer, and that he should see a specialist as soon as possib ...
... border with the pigment spreading into to surrounding skin. Its coloration is varied with some parts being red, some tan and some black. You tell Ralph that you are concerned that this mole may have developed into melanoma, a type of skin cancer, and that he should see a specialist as soon as possib ...
Genes - Gerstein Lab Publications
... determining rates of genomic DNA loss for an organism: a smaller complement of pseudogenes in a genome implies a greater net loss of genomic DNA [10, 16]. Petrov et al. [16] demonstrated experimentally, using dead copies of retrotransposons as ‘pseudogene surrogates’, that the rates of DNA loss in D ...
... determining rates of genomic DNA loss for an organism: a smaller complement of pseudogenes in a genome implies a greater net loss of genomic DNA [10, 16]. Petrov et al. [16] demonstrated experimentally, using dead copies of retrotransposons as ‘pseudogene surrogates’, that the rates of DNA loss in D ...
Chapter 15 ppt - Bremen High School District 228
... different chromosomes, the alleles from the F1 dihybrid would sort into gametes independently, and we would expect to see equal numbers of the four types of offspring. If these two genes were on the same chromosome, we would expect each allele combination, B+ vg+ and b vg, to stay together as gamete ...
... different chromosomes, the alleles from the F1 dihybrid would sort into gametes independently, and we would expect to see equal numbers of the four types of offspring. If these two genes were on the same chromosome, we would expect each allele combination, B+ vg+ and b vg, to stay together as gamete ...