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Management of Status Epilepticus (SE)
Management of Status Epilepticus (SE)

... by 0.05-2 mg/kg/hr IV infusion or o Propofol 1-2 mg/kg IV bolus followed by 20-50 mcg/kg/min IV infusion or o Pentobarbital 5-15 mg/kg IV bolus followed by 0.5-5 mg/kg/IV infusion or o Ketamine 0.5-5 mg/kg IV bolus followed by 0.5-10 mg/kg/hr IV infusion ...
Suggestion from clinicians
Suggestion from clinicians

... with long-term, high-dose therapy. The cardiovascular risk conferred by non-aspirin NSAIDs is likely associated with inhibition of COX-2– mediated production of PGI2 , which has a cardioprotective role in the circulatory system, promoting vasodilation, preventing platelet activation and cell adhesio ...
Prescribing Information
Prescribing Information

... Patients who are receiving a beta-adrenergic blocking agent either orally or intravenously and COMBIGAN® should be observed for potential additive effects of beta-blockade, both systemic and on intraocular pressure. The concomitant use of two topical beta-adrenergic blocking agents is not recommende ...
leukotriene pathway inhibitors
leukotriene pathway inhibitors

... parts of R and S albuterol, • The S isomer may have some proinflammatory effects and binds to the ß2-receptor weakly, but for a longer period. S-isomer pharmacologically inert; may increase airway hyperreactivity, inc. in eosinophil activity and histamine production ...
The Need and Importance of Dose Flexibility - Accu
The Need and Importance of Dose Flexibility - Accu

... there are over 30 million Americans on statins.4 Dose adjustments during the first year are frequent as patients are titrated (or dose-adjusted) according to their cholesterol goals and response to therapy. Even after one full year of statin therapy, where “dose stabilization” has occurred, 17% of p ...
Dupixent - Regeneron
Dupixent - Regeneron

... The safety profile of DUPIXENT + TCS through Week 52 was generally consistent with the safety profile observed at Week 16. ...
Prospective Clinical Trial of Mediflex Posterior Chamber Acrylic
Prospective Clinical Trial of Mediflex Posterior Chamber Acrylic

... The Mediflex cumulative and persistent adverse event rates at 12 months are lower than the FDA historical control grids in all areas except macular edema and raised IOP requiring treatment, but these rates are not statistically significantly different from the FDA grid rates given the small sample s ...
Avastin promising in eyes with branch and retinal vein occlusions
Avastin promising in eyes with branch and retinal vein occlusions

... anatomic and functional benefits without causing complications. Relative to alternatives, such as intravitreal steroid treatment, which is associated with high rates of glaucoma, cataract, and pseudoendophthalmitis, or panretinal laser photocoagulation, which can result in visual field loss, night b ...
TESTOPEL - Endo Pharmaceuticals
TESTOPEL - Endo Pharmaceuticals

... testosterone replacement therapy in men. To date, epidemiologic studies and randomized controlled trials have been inconclusive for determining the risk of major adverse cardiovascular events (MACE), such as non-fatal myocardial infarction, non-fatal stroke, and cardiovascular death, with the use of ...
darbepoetin - Cancer Care Ontario
darbepoetin - Cancer Care Ontario

... reduction in the frequency of administration. Darbepoetin alfa is used for the non­emergency  increase/maintenance of red cell levels, and to decrease the need for transfusions in patients who  do not have other reversible anemias such as iron or folate deficiencies, hemolysis or  gastrointestinal b ...
Anaflex
Anaflex

... The usual dose of Anaflex® is 500 mg should be given initially, then 500mg at least 30 minutes after the initial dose. Children over 5 years: In juvenile arthritis (children over 5 years): The usual dosage of Anaflex® is 10 mg/kg/day taken in two doses at 12-hour intervals is recommended. Anaflex® G ...
Lorazepam Drug Information
Lorazepam Drug Information

... An experiment was conducted to compare pharmacokinetics of sublingual lorazepam with IV, IM and oral lorazepam [4]. Methods: A randomized, single-dose five-way crossover design was utilized [4]. Each subject was given single 2 mg dose of lorazepam at five different times via five different routes (I ...
BERBERIS ARISTATA TETRACHLORIDE INDUCED HEPATOTOXICITY IN RATS
BERBERIS ARISTATA TETRACHLORIDE INDUCED HEPATOTOXICITY IN RATS

... Liver is a vital organ of the body which maintains metabolic homoeostasis. These functions include the synthesis of most essential serum proteins, regulation of nutrients, production of bile and metabolism of xenobiotics. As the primary organ for detoxification of endogenous as well as exogenous com ...
Phosphatidylcholine in the treatment of localized fat
Phosphatidylcholine in the treatment of localized fat

... injections less than 1 cm below the epidermal surface, lack of pre- and post-application care, and perhaps most importantly, administration of the medication by unqualified persons. Among the possible complications that may also occur are infections, allergic reactions, tissue necrosis, and irregula ...
Orenitram Nutrition Guide
Orenitram Nutrition Guide

... *Values may vary according to brand and calculator used. ...


... • Narrow spectrum: Aerobic gram + plus some "atyplcals": • Chlamydia, Mycoplasma, Spirochetes, and legionella • Medical Uses: • Strep and staph • SyphiliS, gonorrhea, chlamydia • Mycoplasma pneumonia • Diphtheria • legionnaire's Disease (all macrolides) • Adverse effects: GI pain, diarrhe ...
Diamide, Capsule
Diamide, Capsule

... Women who are pregnant or breastfeeding infants should therefore be advised to consult their doctor for appropriate treatment, ...
PDF file - Via Medica Journals
PDF file - Via Medica Journals

... based on heart rate acceleration by isoprenaline or cardiac pacing, potassium (if hypokalemic) and intravenous magnesium sulfate [5]. Other alternative or non drug therapy is removing causative ...
taking care
taking care

... Tell your doctor if you have any side effect that bothers you or does not go away. Tell your doctor about all of the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. IBRANCE and other medicines may affect each other, causing side effects. D ...
Acetazolamide: Considerations for Systemic Administration
Acetazolamide: Considerations for Systemic Administration

... The diuresis associated with acetazolamide may be temporary due to the high number of carbonic anhydrase enzymes in the kidneys; this may require very high doses of the drug to be effective, which also exposes the patient to greater risk of adverse effects. Moreover, some patients develop drug toler ...
Full Prescribing Information
Full Prescribing Information

... Pregnancy Category C There are no adequate and well controlled studies of HYCOFENIX in pregnant women. Reproductive toxicity studies have not been conducted with HYCOFENIX; however, studies are available with an individual active ingredient or related active ingredient. Hydrocodone was teratogenic i ...
Word 60KB
Word 60KB

... a Grade 3, 4 or 5 immune mediated AE. The risk of these immunemediated events may be higher in clinical practice than that observed during the trial. This conclusion applies to patients with tumours which do not have an activating Epidermal Growth Factor Receptor (EGFR) gene mutation or Anaplastic l ...
Hydroxyurea - Thalassemia Dubai
Hydroxyurea - Thalassemia Dubai

... encouraging but is not as strong as in adults. ...
View SPC - Veterinary Medicines Directorate
View SPC - Veterinary Medicines Directorate

... gastrointestinal tract. This allows them to be passively swept along by peristalsis and be voided live in faeces. If the drug is quickly voided by the host, for example if a purgative accompanies drug administration, then a narcotized worm may regain its motility and re-establish a position in the g ...
CINERARIA LINN AGAINST CARBON TETRACHLORIDE INDUCED HEPATOTOXICITY Research Article VELMURUGAN V
CINERARIA LINN AGAINST CARBON TETRACHLORIDE INDUCED HEPATOTOXICITY Research Article VELMURUGAN V

... exogenous xenobiotic, drugs, viral infection and chronic alcoholism. The liver is involved with almost all the biochemical pathways to growth, fight against disease, nutrient supply, energy provision and reproduction [1]. The major functions of the liver are carbohydrate, protein and fat metabolism, ...
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Ofloxacin



Ofloxacin is a synthetic antibiotic of the fluoroquinolone drug class considered to be a second-generation fluoroquinolone.Ofloxacin was first patented in 1982 (European Patent Daiichi) and received approval from the U.S. Food and Drug Administration (FDA) on December 28, 1990. Ofloxacin is sold under a wide variety of brand names as well as generic drug equivalents, for oral and intravenous administration. Ofloxacin is also available for topical use, as eye drops and ear drops (marketed as Ocuflox and Floxin Otic respectively in the United States and marketed as Optiflox, eylox respectively in Jordan and Saudi Arabia).Ofloxacin is a racemic mixture, which consists of 50% levofloxacin (the biologically active component) and 50% of its “mirror image” or enantiomer dextrofloxacin.Ofloxacin has been associated with adverse drug reactions, such as tendon damage (including spontaneous tendon ruptures) and peripheral neuropathy (which may be irreversible); tendon damage may manifest long after therapy had been completed, and, in severe cases, may result in lifelong disabilities.
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