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Pulmozyme - Genentech
Pulmozyme - Genentech

... serum concentrations of DNase above normal endogenous levels. After administration of up to 2.5 mg of PULMOZYME twice daily for six months to 321 CF patients, no accumulation of serum DNase was noted. Dornase alfa is expected to be metabolized by proteases present in biological fluids. A human intra ...
2. Anti bacterial chemotherapy
2. Anti bacterial chemotherapy

... and that bacterial growth in the vicinity of the mould had been inhibited. He isolated the mould in pure culture and demonstrated that it produced an antibacterial substance, which he called penicillin. This substance was subsequently extracted and its antibacterial effects analysed by Florey, Chain ...
Piriton™ Tablets
Piriton™ Tablets

... Adults: 1 tablet three or four times a day. Children (aged 6 to 12 years): ½ tablet three or four times a day. Not recommended for children under the age of 6 years. Medical advice should be sought for patients with kidney or liver problems. Contraindications Piriton is contra-indicated in patients ...
Perioperative care of the eye
Perioperative care of the eye

... •  Hold the dropper tip down all the time. This stops the drops from flowing back into the bulb where there may be bacteria that can get into the medicine. •  The eye drops must be kept clean. Avoid touching the dropper against the eye or anything else. •  Have patient lie down or tilt back their he ...
Colloids
Colloids

... • Refers the the proportion of molecules that  are hydroxyethylated at the C2 vs he C6  position. • A higher C2:C6 ratio results in longer  intravascular half life. ...
Torax®
Torax®

... renal impairment (serum creatinine> 160 micromol/l), a history of asth ma, children under 16 years of age. Ketorolac tromethamine is contra-indicated as prophylactic analgesia before surgery due to inhibition of platelet aggregation and is contra-indicated intraoperatively because of the increased r ...
grand-round-ik-141016-v1 - Continuous Learning, Education
grand-round-ik-141016-v1 - Continuous Learning, Education

... ◦ delays in initiation of effective therapy ◦ lack of effective antimicrobial therapy ...
Oral Anti-diabetic Drugs in Special Populations
Oral Anti-diabetic Drugs in Special Populations

... risk of cardiovascular morbidity and mortality.  It is also important to note that none of the ...
Community-Acquired Pneumonia Drug Resistance Patterns Prove
Community-Acquired Pneumonia Drug Resistance Patterns Prove

... among such patients and should no longer be used routinely. However, Bishai and others disagree with that conclusion, arguing that macrolides are continuing to work clinically and that in vitro test data are providing a misleading picture about the extent of macrolide resistance. Lonk’s case-contro ...
Chlormet® Eye Drops - Beximco Pharmaceuticals Ltd.
Chlormet® Eye Drops - Beximco Pharmaceuticals Ltd.

... For steroid-responsive inflammatory ocular condition for which a corticosteriod is indicated and where bacterial infection or a risk of bacterial ocular infection exists. For inflammatory conditions of the palpebral and bulbar conjunctiva, cornea and anterior segment of the globe where the inherent ...
amphotericin B
amphotericin B

... Flucytosine(5-FC) for systemic fungal infection, such as cryptococcal meningitis. But this therapy is useful only when the patient had a normal renal function with hemodialysis, since both drugs have very strong nephrotoxicity. • The irreversible form of amphotericin nephrotoxicity usually occurs in ...
Focalin - Novartis
Focalin - Novartis

... previously treated patients aged 6 to 17 years old with a DSM-IV diagnosis of Attention Deficit Hyperactivity Disorder (ADHD). Both studies included all 3 subtypes of ADHD, i.e., Combined Type, Predominantly Inattentive Type, or Predominantly Hyperactive-Impulsive Type. While both children and adole ...
Penicillins Resistant to Staph Beta
Penicillins Resistant to Staph Beta

... Vancomycin is a glycopeptide antibiotic produced by Streptomyces orientalis. It is a cup-shaped molecule composed of a peptide linked to a disaccharide. The antibiotic blocks peptidoglycan synthesis by inhibiting the transpeptidation step that cross-links adjacent peptidoglycan strands. The resultin ...
Eylea® 40 mg/ml solution for injection in a vial (aflibercept
Eylea® 40 mg/ml solution for injection in a vial (aflibercept

... Each vial should only be used for the treatment of a single eye. The vial contains more than the recommended dose of 2 mg. The extractable volume of the vial (100 microlitres) is not to be used in total. The excess volume should be expelled before injecting. Refer to SmPC for full details. Adults: T ...
Latanoprost Orifarm eye drops, solution ENG SmPC
Latanoprost Orifarm eye drops, solution ENG SmPC

... Myalgia, arthralgia. General disorders and administration site conditions: Very rare: Chest pain. Very rare cases of corneal calcification have been reported with the use of eye drops containing phosphate. In some patients, this has caused significant damage to the cornea. Paediatric population: In ...
a review of pharmacological and pharmaceutical profile of irbesartan
a review of pharmacological and pharmaceutical profile of irbesartan

... h after dosing. Food does not affect the bioavailability of irbesartan. The pharmacokinetics of irbesartan has been compared to the other available angiotensin receptor antagonists (Table1). The oral bioavailability of this AT1 antagonist is relatively high. Irbesartan is more completely absorbed fr ...
Question - MCE Conferences
Question - MCE Conferences

...  Should be stopped temporarily if diarrhea or vomiting occurs ...
Full Prescribing Information for NATRECOR® (nesiritide)
Full Prescribing Information for NATRECOR® (nesiritide)

... subjects requiring either hemofiltration or dialysis. In the PRECEDENT trial, the incidence of elevations in serum creatinine to >0.5 mg/dL above baseline through Day 14 was higher in the NATRECOR® 0.015 mcg/kg/min group (17%) and the NATRECOR® 0.03 mcg/kg/min group (19%) than with standard therapy ...
Inhaler Technology—Improving Prevention and Reversal of
Inhaler Technology—Improving Prevention and Reversal of

... Nursing Mothers: It is not known whether pirbuterol is excreted in human milk. Therefore, MAXAIR AUTOHALER should be used during nursing only if the potential benefit justifies the possible risk to the newborn. Pediatric Use: MAXAIR AUTOHALER is not recommended for patients under the age of 12 years ...
ESTUDO ACT
ESTUDO ACT

... Acetylcysteine represents a safe, non-expensive , easy to administer, and widely available drug THE EVIDENCE Low quality (few trials with allocation concealment, blinding, and ITT analysis) Low statistical power (median trial size = 80 patients) Uncertain effects on clinical endpoints Lack of standa ...
QUALITY EYE CARE STANDARDS AND MANAGED CARE FOR …
QUALITY EYE CARE STANDARDS AND MANAGED CARE FOR …

... Inhibit DNA synthesis (DNA gyrase) Broad spectrum of activity in vitro Low toxicity Excellent penetration ...
Ocular side-effects of urological pharmacy
Ocular side-effects of urological pharmacy

... Continuous advances in the treatment of several urological diseases and conditions are associated with the development of novel drugs and the evolution of older agents as well. The above may have led to a rising number of prescriptions of urological medications by non-specialized physicians, an evol ...
the_body_of_the_text
the_body_of_the_text

... including gentamycin, are considered among the most useful classes ...
5.563"
5.563"

... lymph and circulation, and are redistributed. • Drug Interactions PS can potentially interact with some anticholinergic and cholinergic medications.  It is recommended to consult with a physician about Vayacog® interactions that may apply to specific medical conditions. • Toxicity Vayacog®, similar ...
Azeptin Azeptin
Azeptin Azeptin

... Note) In the event of such symptoms, treatment should be discontinued. 3. Use in the Elderly Since the elderly often have a physiological hypofunction, it is advisable to take measures, such as reduction in dosage, under careful supervision. 4. Use during Pregnancy, Delivery or Lactation (1) AZEPTIN ...
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Ofloxacin



Ofloxacin is a synthetic antibiotic of the fluoroquinolone drug class considered to be a second-generation fluoroquinolone.Ofloxacin was first patented in 1982 (European Patent Daiichi) and received approval from the U.S. Food and Drug Administration (FDA) on December 28, 1990. Ofloxacin is sold under a wide variety of brand names as well as generic drug equivalents, for oral and intravenous administration. Ofloxacin is also available for topical use, as eye drops and ear drops (marketed as Ocuflox and Floxin Otic respectively in the United States and marketed as Optiflox, eylox respectively in Jordan and Saudi Arabia).Ofloxacin is a racemic mixture, which consists of 50% levofloxacin (the biologically active component) and 50% of its “mirror image” or enantiomer dextrofloxacin.Ofloxacin has been associated with adverse drug reactions, such as tendon damage (including spontaneous tendon ruptures) and peripheral neuropathy (which may be irreversible); tendon damage may manifest long after therapy had been completed, and, in severe cases, may result in lifelong disabilities.
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