PrCIPRO® XL - Bayer Canada
... fluoroquinolone-associated tendinitis and tendon rupture is further increased in older patients usually over 60 years of age, in patients taking corticosteroid drugs, and in patients with kidney, heart, or lung transplants. Factors, in addition to age and corticosteroid use, that may independently i ...
... fluoroquinolone-associated tendinitis and tendon rupture is further increased in older patients usually over 60 years of age, in patients taking corticosteroid drugs, and in patients with kidney, heart, or lung transplants. Factors, in addition to age and corticosteroid use, that may independently i ...
CIPRO XL PRODUCT MONOGRAPH
... fluoroquinolone-associated tendinitis and tendon rupture is further increased in older patients usually over 60 years of age, in patients taking corticosteroid drugs, and in patients with kidney, heart, or lung transplants. Factors, in addition to age and corticosteroid use, that may independently i ...
... fluoroquinolone-associated tendinitis and tendon rupture is further increased in older patients usually over 60 years of age, in patients taking corticosteroid drugs, and in patients with kidney, heart, or lung transplants. Factors, in addition to age and corticosteroid use, that may independently i ...
PrCIPRO® XL
... fluoroquinolone-associated tendinitis and tendon rupture is further increased in older patients usually over 60 years of age, in patients taking corticosteroid drugs, and in patients with kidney, heart, or lung transplants. Factors, in addition to age and corticosteroid use, that may independently i ...
... fluoroquinolone-associated tendinitis and tendon rupture is further increased in older patients usually over 60 years of age, in patients taking corticosteroid drugs, and in patients with kidney, heart, or lung transplants. Factors, in addition to age and corticosteroid use, that may independently i ...
PRODUCT MONOGRAPH PrMONUROL® Fosfomycin powder, 3g
... Fosfomycin is bactericidal in urine at therapeutic doses. Its bactericidal action is due to inactivation of the enzyme enolpyruvyl transferase, thereby blocking the condensation of uridine diphosphate-Nacetylglucosamine with p-enolpyruvate, one of the first steps in bacterial cell synthesis. It also ...
... Fosfomycin is bactericidal in urine at therapeutic doses. Its bactericidal action is due to inactivation of the enzyme enolpyruvyl transferase, thereby blocking the condensation of uridine diphosphate-Nacetylglucosamine with p-enolpyruvate, one of the first steps in bacterial cell synthesis. It also ...
amoxicillin: a broad spectrum antibiotic
... related to ampicillin with the same spectrum of activity and potency but is much better absorbed when given orally, achieving blood concentrations approximately twice as high as those obtained with ampicillin (Fig. 5)24. ...
... related to ampicillin with the same spectrum of activity and potency but is much better absorbed when given orally, achieving blood concentrations approximately twice as high as those obtained with ampicillin (Fig. 5)24. ...
Apo-Amoxi
... Treatment should should be continued continued for for a minimum minimum of 48 to 72 hours beyond the time that the patient becomes asymptomatic or evidence of bacterial eradication has been obtained. It is recommended that there be at least 10 days treatment for any infection caused by haemolytic s ...
... Treatment should should be continued continued for for a minimum minimum of 48 to 72 hours beyond the time that the patient becomes asymptomatic or evidence of bacterial eradication has been obtained. It is recommended that there be at least 10 days treatment for any infection caused by haemolytic s ...
FLUOROQUINOLONES - American Academy of Veterinary
... Chlamydia, mycobacteria, mycoplasma, and ureaplasma can also be moderately to very susceptible to fluoroquinolones.{R-9} Local factors that affect activity are cations at the site of infection and low pH; however, fluoroquinolones are active in abscesses in spite of often unfavorable environmental c ...
... Chlamydia, mycobacteria, mycoplasma, and ureaplasma can also be moderately to very susceptible to fluoroquinolones.{R-9} Local factors that affect activity are cations at the site of infection and low pH; however, fluoroquinolones are active in abscesses in spite of often unfavorable environmental c ...
CIPRO XR 81532274, R.1 02/11
... The elimination kinetics of ciprofloxacin are similar for the immediate-release and the CIPRO XR tablet. In studies comparing the CIPRO XR and immediate-release ciprofloxacin, approximately 35% of an orally administered dose was excreted in the urine as unchanged drug for both formulations. The urin ...
... The elimination kinetics of ciprofloxacin are similar for the immediate-release and the CIPRO XR tablet. In studies comparing the CIPRO XR and immediate-release ciprofloxacin, approximately 35% of an orally administered dose was excreted in the urine as unchanged drug for both formulations. The urin ...
Ceftolozane (as sulfate) / Tazobactam (as sodium salt)
... information on resistance is desirable, particularly when treating severe infections. As necessary, expert microbiology advice should be sought when the local prevalence of resistance is such that the utility of the agent in at least some types of infections is questionable. Susceptibility of specif ...
... information on resistance is desirable, particularly when treating severe infections. As necessary, expert microbiology advice should be sought when the local prevalence of resistance is such that the utility of the agent in at least some types of infections is questionable. Susceptibility of specif ...
vigamox - Vision Institute of Canada
... than 1.1 million units sold) have been reported at an incidence of less than 0.01%. The most frequently reported adverse reactions with VIGAMOX® solution based on post-marketing reports include: Eye disorders: endophthalmitis, eye irritation, corneal infiltrates, anterior chamber cells, corneal depo ...
... than 1.1 million units sold) have been reported at an incidence of less than 0.01%. The most frequently reported adverse reactions with VIGAMOX® solution based on post-marketing reports include: Eye disorders: endophthalmitis, eye irritation, corneal infiltrates, anterior chamber cells, corneal depo ...
Traveler`s Diarrhea - Division of General Internal Medicine
... to 55 percent of persons who travel from developed countries to developing countries are affected.1,2 A study3 of Americans visiting developing countries found that 46 percent acquired diarrhea. The classic definition of traveler’s diarrhea is three or more unformed stools in 24 hours with at least ...
... to 55 percent of persons who travel from developed countries to developing countries are affected.1,2 A study3 of Americans visiting developing countries found that 46 percent acquired diarrhea. The classic definition of traveler’s diarrhea is three or more unformed stools in 24 hours with at least ...
6. Kelly CP. A 76-year-old man with recurrent
... antibiotic therapy, such as adverse effects associated with specific antibiotics, and the safe administration and monitoring of patients receiving antibiotics can appear daunting. However, issues of antibiotic therapy may be approached by knowing the adverse effects common to all antibiotics, those ...
... antibiotic therapy, such as adverse effects associated with specific antibiotics, and the safe administration and monitoring of patients receiving antibiotics can appear daunting. However, issues of antibiotic therapy may be approached by knowing the adverse effects common to all antibiotics, those ...
Michael Nailor - Hartford Hospital
... K, Barshikar S, Dolman HS, Baylor AE, Wilson RF. Impact of evaluating antibiotic concentrations in abdominal abscesses percutaneously drain. The American Journal of Surgery, 201: 348-352, ...
... K, Barshikar S, Dolman HS, Baylor AE, Wilson RF. Impact of evaluating antibiotic concentrations in abdominal abscesses percutaneously drain. The American Journal of Surgery, 201: 348-352, ...
Macrolides and ketolides: azithromycin, clarithromycin, telithromycin * Jerry M. Zuckerman, MD
... significantly exceeded plasma levels 8 hours after dosing and maintained elevated levels (23 and 2.15 mg/L) 24 and 48 hours after dosing [29]. Concentrations of telithromycin in bronchial mucosa and epithelial lining fluid exceeded for 24 hours the mean MIC90 of S pneumoniae, Moraxella catarrhalis, an ...
... significantly exceeded plasma levels 8 hours after dosing and maintained elevated levels (23 and 2.15 mg/L) 24 and 48 hours after dosing [29]. Concentrations of telithromycin in bronchial mucosa and epithelial lining fluid exceeded for 24 hours the mean MIC90 of S pneumoniae, Moraxella catarrhalis, an ...
the aminoglycosides - University of Illinois College of Veterinary
... administration, a low volume of distribution (usually in the 0.2 - 0.4 L/kg range, which approximates extracellular fluid volume), and minimal distribution to the CNS. Volumes of distribution are expected to be higher in neonates due to the higher amount of ECF. Their highest tissue concentrations a ...
... administration, a low volume of distribution (usually in the 0.2 - 0.4 L/kg range, which approximates extracellular fluid volume), and minimal distribution to the CNS. Volumes of distribution are expected to be higher in neonates due to the higher amount of ECF. Their highest tissue concentrations a ...
Suprax (cefixime)
... Reproduction studies have been performed in mice and rats at doses up to 400 times the human dose and have revealed no evidence of impaired fertility or harm to the fetus due to cefixime. Because animal reproduction studies are not always predictive of human response, this drug should be used during ...
... Reproduction studies have been performed in mice and rats at doses up to 400 times the human dose and have revealed no evidence of impaired fertility or harm to the fetus due to cefixime. Because animal reproduction studies are not always predictive of human response, this drug should be used during ...
... Ciprofloxacin was recommended to most of those individuals for all or part of the prophylaxis regimen. Some persons were also given anthrax vaccine or were switched to alternative antibiotics. No one who received ciprofloxacin or other therapies as prophylactic treatment subsequently developed inhal ...
Clindamycin in 0.9% Sodium Chloride Injection
... with severe colitis which may end fatally, it should be reserved for serious infections where less toxic antimicrobial agents are inappropriate [see Indications and Usage (1)]. It should not be used in patients with nonbacterial infections such as most upper respiratory tract infections. C. difficil ...
... with severe colitis which may end fatally, it should be reserved for serious infections where less toxic antimicrobial agents are inappropriate [see Indications and Usage (1)]. It should not be used in patients with nonbacterial infections such as most upper respiratory tract infections. C. difficil ...
NEW ZEALAND DATA SHEET Ospamox
... Following single dose therapy of acute lower urinary tract infections, the urine should be cultured. A positive culture may be evidence of a complicated or upper urinary tract infection, and higher dose or prolonged course of treatment may be appropriate. Following administration of ampicillin to pr ...
... Following single dose therapy of acute lower urinary tract infections, the urine should be cultured. A positive culture may be evidence of a complicated or upper urinary tract infection, and higher dose or prolonged course of treatment may be appropriate. Following administration of ampicillin to pr ...
PRODUCT MONOGRAPH Pr CILOXAN® 0.3% Ciprofloxacin
... Anaphylactic reactions following the first dose, have been reported in patients receiving therapy with quinolones by systemic administration. Some reactions were accompanied by cardiovascular collapse, loss of consciousness, tingling, pharyngeal or facial edema, dyspnea, urticaria, and itching. Only ...
... Anaphylactic reactions following the first dose, have been reported in patients receiving therapy with quinolones by systemic administration. Some reactions were accompanied by cardiovascular collapse, loss of consciousness, tingling, pharyngeal or facial edema, dyspnea, urticaria, and itching. Only ...
Rocephin Prescribing Information
... Rocephin and other antibacterial drugs, Rocephin should be used only to treat or prevent infections that are proven or strongly suspected to be caused by susceptible bacteria. When culture and susceptibility information are available, they should be considered in selecting or modifying antibacterial ...
... Rocephin and other antibacterial drugs, Rocephin should be used only to treat or prevent infections that are proven or strongly suspected to be caused by susceptible bacteria. When culture and susceptibility information are available, they should be considered in selecting or modifying antibacterial ...
Full Prescribing Information
... Uncomplicated urethral, endocervical, or rectal infection caused by Chlamydia trachomatis: 100 mg by mouth twice a day for 7 days. As an alternate dosing regimen for uncomplicated urethral or endocervical infection caused by Chlamydia trachomatis, administer 200 mg by mouth once-a-day for 7 days. Un ...
... Uncomplicated urethral, endocervical, or rectal infection caused by Chlamydia trachomatis: 100 mg by mouth twice a day for 7 days. As an alternate dosing regimen for uncomplicated urethral or endocervical infection caused by Chlamydia trachomatis, administer 200 mg by mouth once-a-day for 7 days. Un ...
Daptomycin Use in United States Children*s Hospitals
... • A class of antibiotics with a spectrum of activity similar to that of vancomycin, • Daptomycin is highly bactericidal against S. aureus and other G+ bacteria. • FDA Approrved drug, • Daptomycin is inactivated by surfactant and should NOT be used to treat pneumonia. ...
... • A class of antibiotics with a spectrum of activity similar to that of vancomycin, • Daptomycin is highly bactericidal against S. aureus and other G+ bacteria. • FDA Approrved drug, • Daptomycin is inactivated by surfactant and should NOT be used to treat pneumonia. ...
Ranzith®
... The extensive tissue distribution was confirmed by examination of additional tissues and fluids (bone, ejaculum, prostate, ovary, uterus, salpinx, stomach, liver, and gallbladder). Metabolism: Liver; CYP450: unknown Elimination: Terminal elimination half life (T1/2): 68 hours.The prolonged terminal ...
... The extensive tissue distribution was confirmed by examination of additional tissues and fluids (bone, ejaculum, prostate, ovary, uterus, salpinx, stomach, liver, and gallbladder). Metabolism: Liver; CYP450: unknown Elimination: Terminal elimination half life (T1/2): 68 hours.The prolonged terminal ...
DOXYCYCLINE HYCLATE TABLETS, USP Rev. 06/11
... antibacterial agents, including Doxycycline, and may range in severity from mild diarrhea to fatal colitis. Treatment with antibacterial agents alters the normal flora of the colon leading to overgrowth of C. difficile. C. difficile produces toxins A and B which contribute to the development of CDAD ...
... antibacterial agents, including Doxycycline, and may range in severity from mild diarrhea to fatal colitis. Treatment with antibacterial agents alters the normal flora of the colon leading to overgrowth of C. difficile. C. difficile produces toxins A and B which contribute to the development of CDAD ...
Levofloxacin
Levofloxacin (trade names Levaquin (US), Tavanic (EU), and others) is a broad-spectrum antibiotic of the fluoroquinolone drug class, and the levo isomer of its predecessor ofloxacin. Its spectrum of activity includes most strains of bacterial pathogens responsible for respiratory, urinary tract, gastrointestinal, and abdominal infections, including Gram negative (Escherichia coli, Haemophilus influenzae, Klebsiella pneumoniae, Legionella pneumophila, Moraxella catarrhalis, Proteus mirabilis, and Pseudomonas aeruginosa), Gram positive (methicillin-sensitive but not methicillin-resistant Staphylococcus aureus, Streptococcus pneumoniae, Staphylococcus epidermidis, Enterococcus faecalis, and Streptococcus pyogenes), and atypical bacterial pathogens (Chlamydophila pneumoniae and Mycoplasma pneumoniae). Compared to earlier antibiotics of the fluoroquinoline class such as ciprofloxacin, levofloxacin exhibits greater activity towards Gram-positive bacteria but lesser activity toward Gram-negative bacteria, especially Pseudomonas aeruginosa. Levofloxacin and later generation fluoroquinolones are collectively referred to as ""respiratory quinolones"" to distinguish them from earlier fluoroquinolones which exhibited modest activity toward the important respiratory pathogen Streptococcus pneumoniae.Levofloxacin and other fluoroquinolones are valued for their broad spectrum of activity, excellent tissue penetration, and for their availability in both oral and intravenous formulations. Levofloxacin is used alone or in combination with other antibacterial drugs to treat certain bacterial infections including pneumonia, urinary tract infections, and abdominal infections.Levofloxacin and other fluoroquinolones are generally well tolerated, but in rare instances have produced serious adverse reactions such as spontaneous tendon ruptures and irreversible peripheral neuropathy. Tendon damage may manifest months after therapy had been completed. Levofloxacin may cause worsening of myasthenia gravis symptoms, including muscle weakness and breathing problems.