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Blood memory B cells are disturbed and predict the
Blood memory B cells are disturbed and predict the

... rheumatoid factor (RF) by nephelometry (BN Prospec; DadeBehring) and anti–cyclic citrullinated peptide (anti-CCP) IgG antibodies by enzyme-linked immunosorbent assay (ELISA) (DiaSorin). The cutoff values for positivity were 15 IU/liter for RF and 25 IU/liter for anti-CCP antibodies. BAFF was measure ...
Cancer Association of South Africa (CANSA)  Fact Sheet
Cancer Association of South Africa (CANSA) Fact Sheet

... When examined under a microscope, the granulocytes are not fully developed (immature). Over time, these abnormal white blood cells collect in the spleen, causing it to enlarge. They also fill the bone marrow and thereby reducing the number of normal white blood cells, red blood cells and platelets t ...
Carbon based materials for electronic bio-sensing
Carbon based materials for electronic bio-sensing

... case of PET, a moderate use of aqueous solvent and low-temperature ...
Chronic Lymphocytic Leukemia (CLL) - URMC
Chronic Lymphocytic Leukemia (CLL) - URMC

... The course of CLL varies a lot. Most patients do not need treatment at diagnosis, but they need to be monitored carefully for progression of their disease. A small number of patients have advanced disease at diagnosis and require treatment right away, but most will not need treatment until a later t ...
An Increase in B cell and Cytotoxic NK cell
An Increase in B cell and Cytotoxic NK cell

... nervous system (CNS), resulting in reduced intrathecal inflammation [6-8] and improvement in magnetic resonance imaging (MRI) measurements [9]. As a result of the decreased extravasation, a systemic accumulation of circulating NK cells [10], B cells [11] and pro-inflammatory T cells [12] has been ob ...
Biophysical injury mechanisms associated with
Biophysical injury mechanisms associated with

... above 10 7 Hz. At low frequencies (i.e., below radiofrequencies), it distributes so that the electric field strength is nearly uniform across any plane perpendicular to the current path [16,39,52]. The higher the frequency is the shorter the skin depth. At gigahertz frequencies the skin depth is on ...
LOAD CELL CABLING - marco
LOAD CELL CABLING - marco

... A temperature-independent variable resistor or potentio-meter of typically 10Ω is inserted in the + excitation lead of each load cell. There are two methods of trimming with excitation. The first method is to adjust the potentiometers by trial and error whilst moving calibration weights around from ...
Commercializing nanotechnology
Commercializing nanotechnology

... Taking a page from nature, researchers are using biological molecules and structures as scaffolds for building and growing materials at the nanoscale. Exploiting the molecular recognition properties of DNA, for example, Chad Mirkin (Northwestern University, Evanston, IL, USA) and others have organiz ...
Stem Cell Information
Stem Cell Information

... I. Introduction: What are stem cells, and why are they important? (1) Stem cells have the remarkable potential to develop into many different cell types in the body during early life and growth. In addition, in many tissues they serve as a sort of internal repair system, dividing essentially without ...
Pancreas: Anatomy & Physiology - bushelman-hap
Pancreas: Anatomy & Physiology - bushelman-hap

... • Ruphos, another Greek anatomist, gave pancreas its name after few hundred years • Wirsung discovered the pancreatic duct in 1642. • Pancreas as a secretory gland was investigated by Graaf in 1671. ...
2014 Annual Report - Maryland Stem Cell Research Fund
2014 Annual Report - Maryland Stem Cell Research Fund

... since they come from an unrelated donor). In contrast, since the Orgenesis protocol uses the patient’s own cells, these drugs are not needed and the patient is spared their toxic side effects. Global organizations such as the World Health Organizations and the International Diabetes Federation estim ...
ASCSL GA 2015 Immunohematology Review
ASCSL GA 2015 Immunohematology Review

... lack Kell antigens • ZZAP (DTT + papain) –used to remove immunoglobulins and  complement from the surface of red blood cells, commonly when  evaluating a potential autoantibody. ZZAP also deactivates a  multitude of red cell antigens on the red cell surface.  ...
Hematology of Lower Vertebrates
Hematology of Lower Vertebrates

... of a stained peripheral blood film. The basic techniques used in mammalian hematology also apply to that of lower vertebrates, such as birds and reptiles. However, because lower vertebrates have nucleated erythrocytes and thrombocytes, there are a few modifications to the techniques. Also, the morph ...
Metro Cells
Metro Cells

... 4. Metro cells: the latest evolution in small cells Metro cells, the latest evolution in small cells, are based on the same low-cost femtocell technology that has been successfully used in home and enterprise cells, but with enhanced capacity and coverage. With higher processing and transmit power, ...
Paul, her is a little story that mite interest you, its how cell therapy
Paul, her is a little story that mite interest you, its how cell therapy

... The participating doctors were amazed and bombarded the doctor with technical questions as to how this miracle was possible. The Future of Medicine We are entering a new evolution in medicine - the Medicine of Regeneration. Spearheading this new frontier world-wide are scientists, researchers and ac ...
Session 362 Corneal tissue engineering and molecular
Session 362 Corneal tissue engineering and molecular

... Baltimore, MD. Purpose: Collagen fibrillogenesis can be controlled by pH, temperature, and ionic strength. Using these factors, we have previously developed a type I collagen based ‘vitrigel’ biomaterial with cornea mimetic fibril alignment and lamella formation via a controlled self-assembly proces ...
Respiratory Pathology
Respiratory Pathology

... • Seen in the pulmonary artery to the left lung on cut section is a large pulmonary thromboembolus. Such thromboemboli typically originate in the leg veins or pelvic veins of persons who are immobilized. Other contributing factors include trauma to the extremities, hypercoagulable states (Trousseau ...
Understanding BMT - Aplastic Anemia and MDS International
Understanding BMT - Aplastic Anemia and MDS International

... Sexual dysfunction is a common, enduring consequence of systemic cancer treatment Changes in body image, decline in perceived attractiveness Infertility for both men and women Majority of survivors say they were not prepared for changes in sex life ...
PDF file - Via Medica Journals
PDF file - Via Medica Journals

... number of G and D cells in the pyloric part of the human stomach. These differences might be due to different antisera, methods, and species used in each study. But until now, no report has shown the numbers of endocrine cells in healthy human gastrointestinal tract in such large samples. The distri ...
Disorders of White Blood Cells and Lymphoid Tissues
Disorders of White Blood Cells and Lymphoid Tissues

... form blood cells and replenish bone marrow by a process of self-renewal. All the hematopoietic precursors, including the erythroid (red blood cell), myelocyte (granulocyte and monocyte), lymphocyte (T cell and B cell), and megakaryocyte (platelet) series, are derived from a small population of cells ...
Alkaline-Manganese Dioxide
Alkaline-Manganese Dioxide

... 1960-1970 decade, this battery system rapidly became the popular choice of designers in the ever-widening field of consumer electronics. The product information and test data included in this technical bulletin represent Duracell’s newest alkaline battery products. The zinc/potassium hydroxide/manga ...
Aalborg Universitet Jeppesen, Christian; Blanke, Mogens; Zhou, Fan; Andreasen, Søren Juhl
Aalborg Universitet Jeppesen, Christian; Blanke, Mogens; Zhou, Fan; Andreasen, Søren Juhl

... In Fig. 5 it can clearly be seen that when CO is introduced, the fuel cell is rapidly losing performance, by means of a reduction in the cell voltage. The change in performance can also clearly be seen in Fig. 6. The red data shows the fuel cell impedance without CO mixed into the anode gas, and the ...
Acoustic-Based Biosensors
Acoustic-Based Biosensors

... system from MHz range to kHz range [6]. Third, SAW devices have the ability to directly sense mass and mechanical changes in an environment, which makes them more sensitive than other electrical and thermal biosensors. Furthermore, they have numerous advantages in biological applications [6]. These ...
Bone marrow transplant for sickle cell disease
Bone marrow transplant for sickle cell disease

... be able to have their own children in the future. This is a possible side effect of the chemotherapy; however there have been patients who were able to conceive children after having a transplant. If the patient has gone through puberty before having a transplant it may be possible to collect and st ...
single dna molecule detection by on-bead rolling circle amplification
single dna molecule detection by on-bead rolling circle amplification

... per one bead could be detected (n=3), corresponding to a detection ratio of ~1% (Table 2). With 3,000 polystyrene beads in a PCR tube, 250 countable RCA products per one bead could be detected (n=3), corresponding to a detection rate of ~0.04%. Polystyrene bead showed lower detection rate because am ...
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Bio-MEMS



Bio-MEMS is an abbreviation for biomedical (or biological) microelectromechanical systems. Bio-MEMS have considerable overlap, and is sometimes considered synonymous, with lab-on-a-chip (LOC) and micro total analysis systems (μTAS). Bio-MEMS is typically more focused on mechanical parts and microfabrication technologies made suitable for biological applications. On the other hand, lab-on-a-chip is concerned with miniaturization and integration of laboratory processes and experiments into single (often microfluidic) chips. In this definition, lab-on-a-chip devices do not strictly have biological applications, although most do or are amendable to be adapted for biological purposes. Similarly, micro total analysis systems may not have biological applications in mind, and are usually dedicated to chemical analysis. A broad definition for bio-MEMS can be used to refer to the science and technology of operating at the microscale for biological and biomedical applications, which may or may not include any electronic or mechanical functions. The interdisciplinary nature of bio-MEMS combines material sciences, clinical sciences, medicine, surgery, electrical engineering, mechanical engineering, optical engineering, chemical engineering, and biomedical engineering. Some of its major applications include genomics, proteomics, molecular diagnostics, point-of-care diagnostics, tissue engineering, and implantable microdevices.
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