Activation of an inflammatory response is context
... Interestingly, despite the growing interest in understanding the costs of deploying or maintaining immune effectors in natural populations, rarely has ontogeny been taken into account in these studies. This is unfortunate, as there is evidence that not only does the immune system develop differently ...
... Interestingly, despite the growing interest in understanding the costs of deploying or maintaining immune effectors in natural populations, rarely has ontogeny been taken into account in these studies. This is unfortunate, as there is evidence that not only does the immune system develop differently ...
The age-dependent expression of the F18 E. coli receptor
... coli infections appeared to be dependent on the activity of the FUT1 gene, encoding the alpha(1,2)-fucosyltransferase (FUT1) (Meijerink et al., 1997, 2000). Sequencing of the FUT1 gene of pigs resistant to F18+ E. coli infection revealed a transition (G!A) of both alleles on bp 307. This results in ...
... coli infections appeared to be dependent on the activity of the FUT1 gene, encoding the alpha(1,2)-fucosyltransferase (FUT1) (Meijerink et al., 1997, 2000). Sequencing of the FUT1 gene of pigs resistant to F18+ E. coli infection revealed a transition (G!A) of both alleles on bp 307. This results in ...
Curriculum Vitae
... 16. 20123131; PubMed Central PMCID: PMC2892030.Zhang H, Wang P, Papangelopoulos N, Xu Y, Sette A, Bourne PE, Lund O, Ponomarenko J, Nielsen M, Peters B. Limitations of Ab initio predictions of peptide binding to MHC class II molecules. PLoS One. 2010 Feb 17;5(2):e9272. PMCID: PMC2822856 17. Moutaft ...
... 16. 20123131; PubMed Central PMCID: PMC2892030.Zhang H, Wang P, Papangelopoulos N, Xu Y, Sette A, Bourne PE, Lund O, Ponomarenko J, Nielsen M, Peters B. Limitations of Ab initio predictions of peptide binding to MHC class II molecules. PLoS One. 2010 Feb 17;5(2):e9272. PMCID: PMC2822856 17. Moutaft ...
Human ProBNP and proBNP-derived Peptides (BNP and NT
... proBNP biochemistry, such as proBNP/NT-proBNP glycosylation or incomplete proBNP processing, could significantly influence the current approach to both BNP and NT-proBNP measurements. As HyTest researchers demonstrated, NT-proBNP glycosylation negatively affects its recognition by some antibodies (8 ...
... proBNP biochemistry, such as proBNP/NT-proBNP glycosylation or incomplete proBNP processing, could significantly influence the current approach to both BNP and NT-proBNP measurements. As HyTest researchers demonstrated, NT-proBNP glycosylation negatively affects its recognition by some antibodies (8 ...
comparative characterization of porins from salmonella typhio
... JlL) of chromatographed S. typhi 0-901 porin aggregates was injected to HPLC. The chromatographic profile showed ...
... JlL) of chromatographed S. typhi 0-901 porin aggregates was injected to HPLC. The chromatographic profile showed ...
VENEZUELAN EQUINE ENCEPHALITIS VIRUS REPLICON
... thank my advisor, Bob Johnston for the opportunity to work in such a stimulating environment. I am appreciative of his giving me the freedom to pursue new avenues and the opportunity to witness his desire to understanding “how things work.” The support and guidance of Nancy Davis, Clayton Beard, Mar ...
... thank my advisor, Bob Johnston for the opportunity to work in such a stimulating environment. I am appreciative of his giving me the freedom to pursue new avenues and the opportunity to witness his desire to understanding “how things work.” The support and guidance of Nancy Davis, Clayton Beard, Mar ...
EFFECTS OF PSYCHOLOGICAL STRESS ON GLUCOCORTICOID
... inspiring me to join the Navy and see the world, become a nurse to help others in need, and begin this intellectual journey. For my dad, Voravit ("Jim"), your life's journey from Thailand in seek of the "American Dream" has always inspired me to strive to be the best that I can be for you, myself an ...
... inspiring me to join the Navy and see the world, become a nurse to help others in need, and begin this intellectual journey. For my dad, Voravit ("Jim"), your life's journey from Thailand in seek of the "American Dream" has always inspired me to strive to be the best that I can be for you, myself an ...
HPA Guidelines for the Public Health Management of Pertussis (Updated October 2012)
... Since 1991, coverage by second birthday has remained above 90% in England and has exceeded 95% since 2009/10 [10]. During this period, there has been a marked reduction in notifications of pertussis in England and Wales, although the typical 3–4 yearly cyclical pattern continues to occur with 2007/0 ...
... Since 1991, coverage by second birthday has remained above 90% in England and has exceeded 95% since 2009/10 [10]. During this period, there has been a marked reduction in notifications of pertussis in England and Wales, although the typical 3–4 yearly cyclical pattern continues to occur with 2007/0 ...
Green Book: Full - Department of Health
... Vaccines such as pertussis and inactivated poliomyelitis virus (IPV) contain inactivated bacteria or viruses. Other vaccines contain only the antigens that are important for protection. For example, tetanus and diphtheria vaccines contain inactivated toxins (toxoids), influenza vaccine contains a s ...
... Vaccines such as pertussis and inactivated poliomyelitis virus (IPV) contain inactivated bacteria or viruses. Other vaccines contain only the antigens that are important for protection. For example, tetanus and diphtheria vaccines contain inactivated toxins (toxoids), influenza vaccine contains a s ...
Anthrax: Biology of Bacillus anthracis - ePrints@IISc
... ras-MAPKK pathway5 in athymic mice (mice lacking Tcell function due to absence of thymus since embryonic stage). Thus there is a potential for it being used as an anti-cancer drug in the near future. Recently, the crystal structure6 of the LF has been resolved at 2.2 Å. The molecule has dimensions o ...
... ras-MAPKK pathway5 in athymic mice (mice lacking Tcell function due to absence of thymus since embryonic stage). Thus there is a potential for it being used as an anti-cancer drug in the near future. Recently, the crystal structure6 of the LF has been resolved at 2.2 Å. The molecule has dimensions o ...
Canadian Immunization Guide
... The goal of those concerned with immunization is the elimination of vaccinepreventable diseases. Eradication of smallpox has been achieved. Currently, global efforts are directed at the eradication of polio and the elimination of measles. Ongoing immunization programs with high vaccine coverage are ...
... The goal of those concerned with immunization is the elimination of vaccinepreventable diseases. Eradication of smallpox has been achieved. Currently, global efforts are directed at the eradication of polio and the elimination of measles. Ongoing immunization programs with high vaccine coverage are ...
Atypical serological profiles in hepatitis B virus infection Robério A
... mothers [14]. It has been postulated that HBeAg may have an immunoregulatory function in promoting viral persistence [15]. The HBcAg and HBeAg are distinctly recognized by antibodies but, due to their extensive amino acid homology, are highly cross-reactive at the T-cell level [15]. Thus, HBe antige ...
... mothers [14]. It has been postulated that HBeAg may have an immunoregulatory function in promoting viral persistence [15]. The HBcAg and HBeAg are distinctly recognized by antibodies but, due to their extensive amino acid homology, are highly cross-reactive at the T-cell level [15]. Thus, HBe antige ...
... FcγRIIa-H/H131 genotype showed a significant association with mild malaria. The levels of IgG1 and IgG3 subclass antibodies were statistically significantly higher in the mild malaria patients when compared with the severe malaria patients. A reduced risk of severe malaria with IgG3 antibodies in co ...
NS1 antigen ELISA
... nucleic acid to DENV, and virus isolation have been used for laboratory diagnostic assays for dengue. Nonstructural 1 (NS1) antigen which releases from DENV infected cells is also a useful diagnostic tool. The measure of duration and intensity of immune response and the first detection time of antib ...
... nucleic acid to DENV, and virus isolation have been used for laboratory diagnostic assays for dengue. Nonstructural 1 (NS1) antigen which releases from DENV infected cells is also a useful diagnostic tool. The measure of duration and intensity of immune response and the first detection time of antib ...
Characterization of cell-mediated immune responses elicited
... grafting. By contrast, mice with rejected corneal grafts displayed an intermediate DH response at 8 weeks, in which some individual mice still displayed significant DH activity whereas others lost the ability to generate graft-specific DH (Fig. 4). Graft-specific DH reactivity waned over the next 3 ...
... grafting. By contrast, mice with rejected corneal grafts displayed an intermediate DH response at 8 weeks, in which some individual mice still displayed significant DH activity whereas others lost the ability to generate graft-specific DH (Fig. 4). Graft-specific DH reactivity waned over the next 3 ...
Polysaccharide-protein conjugate vaccines
... tion ef?ciency. Simpli?ed puri?cation processes can be employed to separate the conjugate product from the uncon jugated protein and polysaccharide and other small molecule ...
... tion ef?ciency. Simpli?ed puri?cation processes can be employed to separate the conjugate product from the uncon jugated protein and polysaccharide and other small molecule ...
Structures Common to Different Glycans ...tials of Glycobiology
... Crossmatching procedures helped to identify a rare ABO blood group phenotype termed the Bombay phenotype, so named because the first identified individual lived in that city. Affected persons have red cells deficient in H, A, and B antigens, whereas their sera contain IgM antibodies that react with ...
... Crossmatching procedures helped to identify a rare ABO blood group phenotype termed the Bombay phenotype, so named because the first identified individual lived in that city. Affected persons have red cells deficient in H, A, and B antigens, whereas their sera contain IgM antibodies that react with ...
Protective effect of the maternally derived porcine circovirus type 2
... cellular response. Furthermore, piglets that received maternal PCV2-specific memory T lymphocytes mount DTH reactions in response to intradermal injection of PCV2 antigen. The DTH response was PCV2-specific because skin lesions characteristic of the DTH response were only detected upon intradermal i ...
... cellular response. Furthermore, piglets that received maternal PCV2-specific memory T lymphocytes mount DTH reactions in response to intradermal injection of PCV2 antigen. The DTH response was PCV2-specific because skin lesions characteristic of the DTH response were only detected upon intradermal i ...
View/Open - Minerva Access
... compared to that induced by the PAS1K peptide or polymer. PAS1K polymers containing tandem repeats of C3d induced a significantly (p<0.05) stronger maximal proliferative response, at the same antigenic dose, compared to that induced by the PAS1K peptide or polymer. When used as immunogens to prime T ...
... compared to that induced by the PAS1K peptide or polymer. PAS1K polymers containing tandem repeats of C3d induced a significantly (p<0.05) stronger maximal proliferative response, at the same antigenic dose, compared to that induced by the PAS1K peptide or polymer. When used as immunogens to prime T ...
Clinical Synopsis A 32year old female presented with a four year
... melanocyte survival in three cases of vitiligo which had been inactive for 2-5years. Melanoma may develop from these melanocytes that have escaped immune destruction. The mechanisms of immune escape are not clearly known but Le Poole et al9 hypothesized that the tumor escape may be due to early acti ...
... melanocyte survival in three cases of vitiligo which had been inactive for 2-5years. Melanoma may develop from these melanocytes that have escaped immune destruction. The mechanisms of immune escape are not clearly known but Le Poole et al9 hypothesized that the tumor escape may be due to early acti ...
as a PDF
... deficiency in humans. Zinc could also be critical for some cytokine activity. For instance, it has been demonstrated that the production or the biological activity of IL-1, IL-2, IL-3, IL4, IL-6, IFN-g and TNF-a are affected by zinc deficiency. In addition, and as mentioned above, zinc deficiency in ...
... deficiency in humans. Zinc could also be critical for some cytokine activity. For instance, it has been demonstrated that the production or the biological activity of IL-1, IL-2, IL-3, IL4, IL-6, IFN-g and TNF-a are affected by zinc deficiency. In addition, and as mentioned above, zinc deficiency in ...
Locally delivered polyclonal antibodies potentiate the efficacy
... systemic antibiotics to manage and control the threat of infection in many indications. Antibiotic resistant pathogens are an increasingly problematic cause of hospital-based infections.1 A wide variety of pathogens now demonstrate clinical resistance to antibiotics of choice including methicillin r ...
... systemic antibiotics to manage and control the threat of infection in many indications. Antibiotic resistant pathogens are an increasingly problematic cause of hospital-based infections.1 A wide variety of pathogens now demonstrate clinical resistance to antibiotics of choice including methicillin r ...
Biological Feasibility of Measles Eradication
... Recent progress in reducing global measles mortality has renewed interest in measles eradication. Three biological criteria are deemed important for disease eradication: (1) humans are the sole pathogen reservoir; (2) accurate diagnostic tests exist; and (3) an effective, practical intervention is a ...
... Recent progress in reducing global measles mortality has renewed interest in measles eradication. Three biological criteria are deemed important for disease eradication: (1) humans are the sole pathogen reservoir; (2) accurate diagnostic tests exist; and (3) an effective, practical intervention is a ...
What the shark immune system can and cannot provide for the
... antigen and memory for that specific antigen long after an initial immune response. Lymphocytes are the cells that mediate adaptive immunity: B cells making antibodies for humoral immunity and T cells effecting cell-mediated immunity. The B and T lymphocytes develop in the primary lymphoid tissues, ...
... antigen and memory for that specific antigen long after an initial immune response. Lymphocytes are the cells that mediate adaptive immunity: B cells making antibodies for humoral immunity and T cells effecting cell-mediated immunity. The B and T lymphocytes develop in the primary lymphoid tissues, ...
What the shark immune system can and cannot provide for the
... antigen and memory for that specific antigen long after an initial immune response. Lymphocytes are the cells that mediate adaptive immunity: B cells making antibodies for humoral immunity and T cells effecting cell-mediated immunity. The B and T lymphocytes develop in the primary lymphoid tissues, ...
... antigen and memory for that specific antigen long after an initial immune response. Lymphocytes are the cells that mediate adaptive immunity: B cells making antibodies for humoral immunity and T cells effecting cell-mediated immunity. The B and T lymphocytes develop in the primary lymphoid tissues, ...