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evidence based review [2016] (PDF 1.3M)
... were excluded from the main body of this report; however the findings From this reasoning four of the five RCTs are included within Appendix 2 at the end of this report. The main finding from these excluded studies was that there was a paucity of RCTs that have investigated the efficacy of using bis ...
... were excluded from the main body of this report; however the findings From this reasoning four of the five RCTs are included within Appendix 2 at the end of this report. The main finding from these excluded studies was that there was a paucity of RCTs that have investigated the efficacy of using bis ...
Acute Renal Failure aka Acute Kidney Injury
... ANZICS Clinical Trial Group. Lancet 2000;356:2139-2143 ...
... ANZICS Clinical Trial Group. Lancet 2000;356:2139-2143 ...
Scleroderma lung disease - European Respiratory Review
... showed that SSc-ILD patients treated with CYC and prednisone had significant improvement in FVC at 6 and 12 months [61–63]. In 2000, a retrospective cohort study found that patients with abnormal BAL findings who were treated with CYC were more likely to have stabilisation or improvement in FVC and ...
... showed that SSc-ILD patients treated with CYC and prednisone had significant improvement in FVC at 6 and 12 months [61–63]. In 2000, a retrospective cohort study found that patients with abnormal BAL findings who were treated with CYC were more likely to have stabilisation or improvement in FVC and ...
Direct Laboratory Notification of Communicable Diseases
... just because of the information it provides us on broad trends in these diseases, but more importantly because it is the trigger for actions to control outbreaks, and hence protect the health of our communities. More complete and speedy reporting of diseases allows more complete and speedy responses ...
... just because of the information it provides us on broad trends in these diseases, but more importantly because it is the trigger for actions to control outbreaks, and hence protect the health of our communities. More complete and speedy reporting of diseases allows more complete and speedy responses ...
Osteoporosis and Vitamin D deficiency - Ezzat-Murad
... Osteoporotic fractures are those occurring from a fall from a standing height or less, without major trauma Fractures due to osteoporosis have a serious impact on a person’s health, happiness and quality of life. They can result in chronic pain, long-term disability and death. At least one in three ...
... Osteoporotic fractures are those occurring from a fall from a standing height or less, without major trauma Fractures due to osteoporosis have a serious impact on a person’s health, happiness and quality of life. They can result in chronic pain, long-term disability and death. At least one in three ...
Infections and the rise of antimicrobial resistance
... I have chosen infectious diseases as the subject for my first in-depth report for a number of reasons; Globally, this group of diseases represents the greatest cause of death and burden of disease. In developed countries, following the success of vaccination and antimicrobial drug therapy, infectiou ...
... I have chosen infectious diseases as the subject for my first in-depth report for a number of reasons; Globally, this group of diseases represents the greatest cause of death and burden of disease. In developed countries, following the success of vaccination and antimicrobial drug therapy, infectiou ...
INTRODUCTION: corneal blindness accounts for 20
... Antifungal treatment was supplemented with Broad spectrum antibiotics, Cycloplegic, Antiinflammatory agents, Vitamin C and Lubricating eye drops. For mycotic keratitis with secondary glaucoma anti-glaucoma medications were prescribed. For corneal ulcer with small perforation Bandage contact lens, Cy ...
... Antifungal treatment was supplemented with Broad spectrum antibiotics, Cycloplegic, Antiinflammatory agents, Vitamin C and Lubricating eye drops. For mycotic keratitis with secondary glaucoma anti-glaucoma medications were prescribed. For corneal ulcer with small perforation Bandage contact lens, Cy ...
ICH: E 4: Dose response information to support drug registration
... to compare several doses. A comparison of results from two or more controlled trials with single fixed doses might sometimes be informative, e.g., if control groups were similar, although, even in that case, the many across-study differences that occur in separate trials usually make this approach u ...
... to compare several doses. A comparison of results from two or more controlled trials with single fixed doses might sometimes be informative, e.g., if control groups were similar, although, even in that case, the many across-study differences that occur in separate trials usually make this approach u ...
lifestyle medicine – evidence review
... ~70% of modern health problems which have a lifestyle-based cause. [ALMA] Brings together sound scientific evidence from diverse health related fields to assist clinicians in the process of not only treating disease, but also promoting good health. [Rippe, 1999] Requires patients to change high ...
... ~70% of modern health problems which have a lifestyle-based cause. [ALMA] Brings together sound scientific evidence from diverse health related fields to assist clinicians in the process of not only treating disease, but also promoting good health. [Rippe, 1999] Requires patients to change high ...
VOJNOSANITETSKI PREGLED
... Correspondence to: Silva Dobriý, Institute for Scientific Information, Military Medical Academy, Crnotravska 17, 000 Belgrade, Serbia. ...
... Correspondence to: Silva Dobriý, Institute for Scientific Information, Military Medical Academy, Crnotravska 17, 000 Belgrade, Serbia. ...
Key words in plain language
... ecide what is most important. Spend your time on those important activities and with those people who mean the most to you. More tips... •C onsider joining a support group like Arthritis Ireland or seeing a counsellor. Counselling is help from a professional who will listen to you and help you d ...
... ecide what is most important. Spend your time on those important activities and with those people who mean the most to you. More tips... •C onsider joining a support group like Arthritis Ireland or seeing a counsellor. Counselling is help from a professional who will listen to you and help you d ...
Endometriosis Awareness Week-Month
... simply don’t disappear although they do grow smaller. The lesions are generally return to their pretreatment size within three months of the Lupron ™ wearing off. Because of the significant menopausal symptoms during treatment and the potential for bone loss, one should use Lupron™ sparingly. A newe ...
... simply don’t disappear although they do grow smaller. The lesions are generally return to their pretreatment size within three months of the Lupron ™ wearing off. Because of the significant menopausal symptoms during treatment and the potential for bone loss, one should use Lupron™ sparingly. A newe ...
Aspirin Use and All-Cause Mortality Among Patients Being
... Results During 3.1 years of follow-up, 276 patients (4.5%) died. In a simple univariable analysis, there was no association between aspirin use and mortality (4.5% vs 4.5%). However, after adjustment for age, sex, standard cardiovascular risk factors, use of other medications, coronary disease histo ...
... Results During 3.1 years of follow-up, 276 patients (4.5%) died. In a simple univariable analysis, there was no association between aspirin use and mortality (4.5% vs 4.5%). However, after adjustment for age, sex, standard cardiovascular risk factors, use of other medications, coronary disease histo ...
DonorNet Abbreviations
... A decision that individuals who work in the organization may use any abbreviation, acronym or symbol that is not on the list of unacceptable abbreviations. However, if multiple abbreviations, symbols, or acronyms exist for the same term, the organization identifies what will be used to eliminate amb ...
... A decision that individuals who work in the organization may use any abbreviation, acronym or symbol that is not on the list of unacceptable abbreviations. However, if multiple abbreviations, symbols, or acronyms exist for the same term, the organization identifies what will be used to eliminate amb ...
Contracted Assessment Report - Medical Services Advisory
... Enquiries about the content of the report should be directed to the above address. This report is a contracted technical report for use by the Medical Services Advisory Committee (MSAC) to inform its deliberations. MSAC is an independent committee which has been established to provide advice to the ...
... Enquiries about the content of the report should be directed to the above address. This report is a contracted technical report for use by the Medical Services Advisory Committee (MSAC) to inform its deliberations. MSAC is an independent committee which has been established to provide advice to the ...
Australian Public Assessment Report (AUSPAR) for Romiplostim
... structure of romiplostim. The molecule is comprised of two identical subunits. Each subunit consists of a human immunoglobulin IgG1 Fc domain at the N-terminus which is fused at the Cterminus to two thrombopoietin receptor binding domains (TRBD), with each binding domain consisting of a 14-amino aci ...
... structure of romiplostim. The molecule is comprised of two identical subunits. Each subunit consists of a human immunoglobulin IgG1 Fc domain at the N-terminus which is fused at the Cterminus to two thrombopoietin receptor binding domains (TRBD), with each binding domain consisting of a 14-amino aci ...
WCET Journal
... the world and learn from all of them. I try to have articles in multiple languages and have wonderful executive and editorial board members that help me with reviews and translations. Some editions have more ostomy or wound or continence articles. While I strive for a balance in content, I am limite ...
... the world and learn from all of them. I try to have articles in multiple languages and have wonderful executive and editorial board members that help me with reviews and translations. Some editions have more ostomy or wound or continence articles. While I strive for a balance in content, I am limite ...
Dictionary of Pharmaceutical Medicine
... organisations. Many years of experience with new colleagues showed me how useful some sort of booklet might be, that would give them a better understanding of some of the less familiar technical terms and their context. In this dictionary, containing at present more than 800 keywords, the attention ...
... organisations. Many years of experience with new colleagues showed me how useful some sort of booklet might be, that would give them a better understanding of some of the less familiar technical terms and their context. In this dictionary, containing at present more than 800 keywords, the attention ...
To view a copy of this license, visit http://creativecommons.org
... unsafe, and some evidence that successful withdrawal was more likely in those on fewer agents and lower baseline blood pressures. Several months of follow-up is required to determine whether withdrawal has been successful, as half of those who become hypertensive after withdrawal do so after 10 week ...
... unsafe, and some evidence that successful withdrawal was more likely in those on fewer agents and lower baseline blood pressures. Several months of follow-up is required to determine whether withdrawal has been successful, as half of those who become hypertensive after withdrawal do so after 10 week ...
Does neonatal pain management in intensive care units
... as early night+late night. These timings were chosen because in France, most of the day and night nurse shifts start at 7:00 and 19:00, respectively. Descriptive statistics were used to summarise continuous and categorical variables. The outcome was the use of procedural analgesia. We calculated the ...
... as early night+late night. These timings were chosen because in France, most of the day and night nurse shifts start at 7:00 and 19:00, respectively. Descriptive statistics were used to summarise continuous and categorical variables. The outcome was the use of procedural analgesia. We calculated the ...
PDF Version - US Preventive Services Task Force
... association between statin use and diabetes mellitus is mixed, with 1 prevention trial suggesting that there may be a small increased risk of developing diabetes with use of high-dose statins. Myalgia is a commonly reported adverse effect of statins, but placebocontrolled trial data do not support t ...
... association between statin use and diabetes mellitus is mixed, with 1 prevention trial suggesting that there may be a small increased risk of developing diabetes with use of high-dose statins. Myalgia is a commonly reported adverse effect of statins, but placebocontrolled trial data do not support t ...
Hodgkin Disease
... Unexplained loss of more than 10% of body weight within the preceding 6 months o An "A" designation is the absence of the above. o An "X" designation is sometimes used to indicate the presence of bulky disease. Approximately one third of new patients have splenic involvement based on laparotomy ...
... Unexplained loss of more than 10% of body weight within the preceding 6 months o An "A" designation is the absence of the above. o An "X" designation is sometimes used to indicate the presence of bulky disease. Approximately one third of new patients have splenic involvement based on laparotomy ...
PYODERMA GANGRENOSUM: A MINI
... of other NDs.5,27 PG most commonly presents on the lower limbs, namely the pretibial area, but other skin areas (head, neck, breasts, genitalia, and upper extremities) can be involved.5,28 Clinically, the classical form (ulcerative) is characterised by rapidly progressing, painful ulcers with well-d ...
... of other NDs.5,27 PG most commonly presents on the lower limbs, namely the pretibial area, but other skin areas (head, neck, breasts, genitalia, and upper extremities) can be involved.5,28 Clinically, the classical form (ulcerative) is characterised by rapidly progressing, painful ulcers with well-d ...
Miles Stanford - EMA
... the expression of adhesion molecules. These studies have highlighted the important role played by cytokines and chemokines in the attraction and diapedesis of inflammatory cells at the blood retinal barrier (8). Furthermore, in our clinical studies, the value of measuring soluble forms of these adhe ...
... the expression of adhesion molecules. These studies have highlighted the important role played by cytokines and chemokines in the attraction and diapedesis of inflammatory cells at the blood retinal barrier (8). Furthermore, in our clinical studies, the value of measuring soluble forms of these adhe ...
1 Opioids in chronic osteoarthritis pain - A systematic review
... Background: The efficacy, tolerability and safety of opioid therapy in chronic osteoarthritis (OA) pain are under debate. We updated Cochrane systematic reviews on the efficacy and safety of opioids in chronic OA pain published in 2008. Methods: We screened Medline, Scopus, and the Cochrane Library ...
... Background: The efficacy, tolerability and safety of opioid therapy in chronic osteoarthritis (OA) pain are under debate. We updated Cochrane systematic reviews on the efficacy and safety of opioids in chronic OA pain published in 2008. Methods: We screened Medline, Scopus, and the Cochrane Library ...
Epidemiology
Epidemiology is the study of the patterns, causes, and effects of health and disease conditions in defined populations. It is the cornerstone of public health, and shapes policy decisions and evidence-based practice by identifying risk factors for disease and targets for preventive healthcare. Epidemiologists help with study design, collection, and statistical analysis of data, and interpretation and dissemination of results (including peer review and occasional systematic review). Epidemiology has helped develop methodology used in clinical research, public health studies, and, to a lesser extent, basic research in the biological sciences.Major areas of epidemiological study include disease etiology, transmission, outbreak investigation, disease surveillance and screening, biomonitoring, and comparisons of treatment effects such as in clinical trials. Epidemiologists rely on other scientific disciplines like biology to better understand disease processes, statistics to make efficient use of the data and draw appropriate conclusions, social sciences to understand proximate and distal causes better, and engineering for exposure assessment.