
File
... • The most common symptoms are high fever, chills, lethargy, and a rash. • If meningitis is present, the symptoms will also include headache and neck stiffness (which may not be present in infants); seizures may also occur. • Complications: shock, coma, and death can follow within several hours, eve ...
... • The most common symptoms are high fever, chills, lethargy, and a rash. • If meningitis is present, the symptoms will also include headache and neck stiffness (which may not be present in infants); seizures may also occur. • Complications: shock, coma, and death can follow within several hours, eve ...
Emerging Infectious Diseases
... many viral hemorrhagic fevers, LF is not a rare disease that emerges only in outbreak form. Lassa fever is an acute viral illness that occurs in West Africa (eastern Sierra Leone, northern Liberia, southeastern Guinea, and central and southern Nigeria). The illness was discovered in 1969 when two mi ...
... many viral hemorrhagic fevers, LF is not a rare disease that emerges only in outbreak form. Lassa fever is an acute viral illness that occurs in West Africa (eastern Sierra Leone, northern Liberia, southeastern Guinea, and central and southern Nigeria). The illness was discovered in 1969 when two mi ...
Tuberculosis and HIV/AIDS
... Rafael Laniado-Laborin MD, MPH, FCCP Universidad Autónoma de Baja California ...
... Rafael Laniado-Laborin MD, MPH, FCCP Universidad Autónoma de Baja California ...
viral infection
... • Disseminated HZ: in immunocompromised patients and cause gangrenous and necrotic lesions, varicella pneumonia and encephalitis are ...
... • Disseminated HZ: in immunocompromised patients and cause gangrenous and necrotic lesions, varicella pneumonia and encephalitis are ...
Globalization of Diseases
... Public health experts are equally worried that the outbreaks of animal-borne diseases provide new and terrifying opportunities for terrorists. Of the pathogens listed by the CDC as potential agents of bioterrorism, five are zoonotic. All are highly lethal and easily transmitted between people. "The ...
... Public health experts are equally worried that the outbreaks of animal-borne diseases provide new and terrifying opportunities for terrorists. Of the pathogens listed by the CDC as potential agents of bioterrorism, five are zoonotic. All are highly lethal and easily transmitted between people. "The ...
13.0 Other Infectiou.. - Georgia Coastal Health District
... Entamoeba histolytica causes invasive disease. Entamoeba dispar is a noninvasive parasite and does not cause disease. The organisms are excreted as cysts or trophozoites in the feces of infected persons. Transmission occurs when cysts are ingested. Transmission has occasionally been associated with ...
... Entamoeba histolytica causes invasive disease. Entamoeba dispar is a noninvasive parasite and does not cause disease. The organisms are excreted as cysts or trophozoites in the feces of infected persons. Transmission occurs when cysts are ingested. Transmission has occasionally been associated with ...
KASPER/MOLTZAN QUIZ
... a) 1yr graft survival 98%, acute rejection rate in first year ~10%, graft half-life 20-25 years b) 1yr graft survival 95%, acute rejection rate in first year ~20%, graft half-life 15-20 years c) 1yr graft survival 90%, acute rejection rate in first year ~30%, graft half-life 10-15 years ...
... a) 1yr graft survival 98%, acute rejection rate in first year ~10%, graft half-life 20-25 years b) 1yr graft survival 95%, acute rejection rate in first year ~20%, graft half-life 15-20 years c) 1yr graft survival 90%, acute rejection rate in first year ~30%, graft half-life 10-15 years ...
Vancom ycin-resistant Enterococci (VRE)
... environment. Generally these bacteria do not cause illness; however when illness does occur it can usually be treated with antibiotics. Vancomycin-resistant Enterococci (VRE) are strains of enterococci bacteria that are resistant to the antibiotic vancomycin. ...
... environment. Generally these bacteria do not cause illness; however when illness does occur it can usually be treated with antibiotics. Vancomycin-resistant Enterococci (VRE) are strains of enterococci bacteria that are resistant to the antibiotic vancomycin. ...
... never been treated with systemic aminoglycosides before amikacin therapy was administered but had received treatment with both topical neomycin and gentamicin, the possibility exists that there was a selection effect of prior therapy with topical aminoglycosides on aminoglycoside-resistant mutants [ ...
Otitis Media and Mastoiditis Due to Mycobacterium fortuitum: Case
... M fortuitum, most of the reports predate the availability of newer antibiotics with potent activity against this organism (e.g., imipenem, clarithromycin, and the fluoroquinolones). In addition, in two ofthe cases [2, 5], the authors seem to advocate the use of isoniazid, a drug that is inappropriat ...
... M fortuitum, most of the reports predate the availability of newer antibiotics with potent activity against this organism (e.g., imipenem, clarithromycin, and the fluoroquinolones). In addition, in two ofthe cases [2, 5], the authors seem to advocate the use of isoniazid, a drug that is inappropriat ...
Greens - Purpose LLC
... diabetes, not to mention overwhelming infection and cancer.(ii) When used selectively these drugs can help people get their lives back. But they are not a long-term solution. They shouldn’t be the end of treatment, but a bridge to cool off inflammation while we treat the root cause of the disease. T ...
... diabetes, not to mention overwhelming infection and cancer.(ii) When used selectively these drugs can help people get their lives back. But they are not a long-term solution. They shouldn’t be the end of treatment, but a bridge to cool off inflammation while we treat the root cause of the disease. T ...
Research Training - Jobs at LSHTM
... response to infection at the molecular, cellular and population levels. The goals are to develop a greater understanding of basic mechanisms of immunological protection versus pathology, and to apply this knowledge to the development of immunological interventions and the identification of correlate ...
... response to infection at the molecular, cellular and population levels. The goals are to develop a greater understanding of basic mechanisms of immunological protection versus pathology, and to apply this knowledge to the development of immunological interventions and the identification of correlate ...
word doc version
... ME is not a new disease and, until the late 1950s, it was generally considered to be an atypical, non paralytic or milder form of poliomyelitis. However, a new awareness of its disabling potential was first recognised in the more affluent communities of North America and Europe, then engaged in vast ...
... ME is not a new disease and, until the late 1950s, it was generally considered to be an atypical, non paralytic or milder form of poliomyelitis. However, a new awareness of its disabling potential was first recognised in the more affluent communities of North America and Europe, then engaged in vast ...
Preventing measles transmission in health care settings Key points
... Susceptible staff who have been exposed to measles should be removed from patient contact and th st excluded from the 5 to the 21 day after exposure regardless of whether they received vaccine or immunoglobulin after exposure1 If an outbreak occurs in the institution or area served by the inst ...
... Susceptible staff who have been exposed to measles should be removed from patient contact and th st excluded from the 5 to the 21 day after exposure regardless of whether they received vaccine or immunoglobulin after exposure1 If an outbreak occurs in the institution or area served by the inst ...
Homeopathic Alternative To Vaccines
... "Which is the best potency to give for protection? I could not lay down any hard and fast rules myself; I have only been feeling my way so far. A French Homeopathic doctor is reported to have conducted an experiment along these lines for years, and when he published his results later, he claimed tha ...
... "Which is the best potency to give for protection? I could not lay down any hard and fast rules myself; I have only been feeling my way so far. A French Homeopathic doctor is reported to have conducted an experiment along these lines for years, and when he published his results later, he claimed tha ...
Case No2 Medical history, objective data and results of laboratory
... to develop a maculopapular rash and this is especially the case if the patient is inadvertently treated with a beta-lactam antibiotic such as Ampicillin or Amoxicillin. Although IM is most commonly caused by EBV, EBV infection does not always cause IM, it can be asymptomatic or just a mild febrile i ...
... to develop a maculopapular rash and this is especially the case if the patient is inadvertently treated with a beta-lactam antibiotic such as Ampicillin or Amoxicillin. Although IM is most commonly caused by EBV, EBV infection does not always cause IM, it can be asymptomatic or just a mild febrile i ...
Infectious Disease Topics
... Diseases • www.cdc.gov/eid • Vol. 13, No. 6, June 2007 Clinical, Laboratory, and Epidemiologic Features of Murine ...
... Diseases • www.cdc.gov/eid • Vol. 13, No. 6, June 2007 Clinical, Laboratory, and Epidemiologic Features of Murine ...
Encephalitozoonosis (from Encephalitazoon cuniculi) in Rabbits
... that infects rabbits and other mammals. In most cases, it only causes disease in animals that do not have a fully functioning immune system. • Infection occurs when rabbits eat the microscopic spores in urine-contaminated food, such as grass or hay that another rabbit has urinated on. In the normal ...
... that infects rabbits and other mammals. In most cases, it only causes disease in animals that do not have a fully functioning immune system. • Infection occurs when rabbits eat the microscopic spores in urine-contaminated food, such as grass or hay that another rabbit has urinated on. In the normal ...
Association of Ocular Inflammatory Disease with Inflammatory Bowel
... C. Stephen Foster, M.D. Even more surprising than the association between arthritis and eye inflammation, at least to some people, is the association between bowel inflammation and eye inflammation. But history tells us that such an association exists. This may be true not only in infectious inflamm ...
... C. Stephen Foster, M.D. Even more surprising than the association between arthritis and eye inflammation, at least to some people, is the association between bowel inflammation and eye inflammation. But history tells us that such an association exists. This may be true not only in infectious inflamm ...
Sheet 41
... 1) Uncertain etiology.(there is no direct reason for these diseases .e.g (hyperlipidemia is a risk factor for hyepertension but not a cause , genetic factors are risk factor for diabetes but not a cause ) 2) they have multiple risk factors.( these may be high relative risk factor and moderate risk f ...
... 1) Uncertain etiology.(there is no direct reason for these diseases .e.g (hyperlipidemia is a risk factor for hyepertension but not a cause , genetic factors are risk factor for diabetes but not a cause ) 2) they have multiple risk factors.( these may be high relative risk factor and moderate risk f ...
ESKAPE Pathogens - ALS Environmental
... respiratory secretions, urine, wound exudates). S. maltophilia usually bypasses normal host’s defenses to cause human infection. The growth of S. maltophilia from sites which would normally be sterile (e.g., blood) usually represents true infection; growth of S. maltophilia in microbiological cultur ...
... respiratory secretions, urine, wound exudates). S. maltophilia usually bypasses normal host’s defenses to cause human infection. The growth of S. maltophilia from sites which would normally be sterile (e.g., blood) usually represents true infection; growth of S. maltophilia in microbiological cultur ...
File
... antibiotics would severely hinder the capability to control these infections. The population of greatest concern would be hospital patient, particularly those who have impaired immune systems. Immunosupressed individuals will have very little resistance to infections and rely heavily on antibiotics ...
... antibiotics would severely hinder the capability to control these infections. The population of greatest concern would be hospital patient, particularly those who have impaired immune systems. Immunosupressed individuals will have very little resistance to infections and rely heavily on antibiotics ...
Background information
... system to attack healthy tissues in the body and cause inflammation and damage. Anti-TNF medications bind to TNF or its receptor to block its action. Another target is a membrane-bound extracellular protein called ‘beta 7 integrin’. Humanised monoclonal antibodies being investigated for treatment of ...
... system to attack healthy tissues in the body and cause inflammation and damage. Anti-TNF medications bind to TNF or its receptor to block its action. Another target is a membrane-bound extracellular protein called ‘beta 7 integrin’. Humanised monoclonal antibodies being investigated for treatment of ...
Disease Informatics: Quality Aspects for Diseases Associated with
... Group (DIG) need to be well trained in statistics • It is felt that DIG needs to have at least 15 to 20% professional statisticians • Statistician should not be dominated, should be given credit for their work and should be involved early ...
... Group (DIG) need to be well trained in statistics • It is felt that DIG needs to have at least 15 to 20% professional statisticians • Statistician should not be dominated, should be given credit for their work and should be involved early ...
Neurologic Infections
... be primarily involved, or neurologic symptoms can develop as a result of systemic infection. Except in cases of penetrating head trauma or neurosurgery, most infections gain access via other parts of the body. Common sources for brain and intraspinal abscesses include contiguous spread from dental i ...
... be primarily involved, or neurologic symptoms can develop as a result of systemic infection. Except in cases of penetrating head trauma or neurosurgery, most infections gain access via other parts of the body. Common sources for brain and intraspinal abscesses include contiguous spread from dental i ...
Compartmental models in epidemiology

The establishment and spread of infectious diseases is a complex phenomenon with many interacting factors, e.g., the environment in which the pathogen and hosts are situated, the population(s) it is exposed to, and the intra- and inter-dynamics of the population it is exposed to. The role of mathematical epidemiology is to model the establishment and spread of pathogens. A predominant method of doing so, is to use the notion of abstracting the population into compartments under certain assumptions, which represent their health status with respect to the pathogen in the system. One of the cornerstone works to achieve success in this method was done by Kermack and McKendrick in the early 1900s.These models are known as compartmental models in epidemiology, and serve as a base mathematical framework for understanding the complex dynamics of these systems, which hope to model the main characteristics of the system. These compartments, in the simplest case, can stratify the population into two health states: susceptible to the infection of the pathogen (often denoted by S); and infected by the pathogen (given the symbol I). The way that these compartments interact is often based upon phenomenological assumptions, and the model is built up from there. These models are usually investigated through ordinary differential equations (which are deterministic), but can also be viewed in more realistic stochastic framework (for example, the Gillespie model). To push these basic models to further realism, other compartments are often included, most notably the recovered/removed/immune compartment (denoted R).Once one is able to model an infectious pathogen with compartmental models, one can predict the various properties of the pathogen spread, for example the prevalence (total number of infected from the epidemic) and the duration of the epidemic. Also, one can understand how different situations may affect the outcome of the epidemic, e.g., what is the best technique for issuing a limited number of vaccines in a given population?