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Efficacy and Safety of Traditional Medical Therapies for
Efficacy and Safety of Traditional Medical Therapies for

... Division of Gastroenterology, University of Iowa Carver College of Medicine, Iowa City, Iowa ...
1
1

... Adult — In controlled trials used to support the efficacy of fluoxetine, patients were administered morning doses ranging from 20 to 80 mg/day. Studies comparing fluoxetine 20, 40, and 60 mg/day to placebo indicate that 20 mg/day is sufficient to obtain a satisfactory response in Major Depressive Di ...
Diapositive 1 - Moodle Lille 2
Diapositive 1 - Moodle Lille 2

... AMGEN’s counterarguments Sample size similar to the original trial (427 vs 463 patients) Original pre-specified endpoints Vectibix already on US market, KRAS marker has a high clinical significance Strong biological rationale Saves the expenses and side-effects of futile therapy Idea of KRAS mutati ...
- City Research Online
- City Research Online

... Inclusion criteria Publications detailing non surgical management strategies in both the clinical and laboratory setting, which aimed to prevent ulceration or tissue necrosis following cytotoxic drug extravasation into the subcutaneous tissue of humans or animals. Both quantitative and qualitative s ...
Diapositive 1 - Moodle Lille 2
Diapositive 1 - Moodle Lille 2

... AMGEN’s counterarguments Sample size similar to the original trial (427 vs 463 patients) Original pre-specified endpoints Vectibix already on US market, KRAS marker has a high clinical significance Strong biological rationale Saves the expenses and side-effects of futile therapy Idea of KRAS mutati ...


... Postmarketing studies are essential in assessing optimal use of drugs and biologics. Results from such studies have made significant changes to how products are used. Listed below are a few examples of improvement to health care through better treatment regimens or decreased toxicity: Interferon alf ...
Prescribing Information - PI
Prescribing Information - PI

... and in non-cardiac patients. In children given Synagis for a second season, the mean ± SD serum concentrations following the first and fourth injections were 61 ± 17 mcg per mL and 86 ± 31 mcg per mL, respectively. In 139 children less than or equal to 24 months of age with hemodynamically significa ...
Guidelines for choice of selective serotonin reuptake inhibitor in
Guidelines for choice of selective serotonin reuptake inhibitor in

... In our analysis of nine studies comparing sertraline with other SSRIs, there were fewer dropouts attributed to adverse reactions during treatment with sertraline, with a number needed to treat of 19. However, four further studies involving sertraline have since been reported and a preliminary analys ...
Mevacor - Merck.com
Mevacor - Merck.com

... p=0.002), and of undergoing coronary revascularization procedures (e.g., coronary artery bypass grafting or percutaneous transluminal coronary angioplasty) by 33% (3.2 vs. 4.8%; p=0.001). Trends in risk reduction associated with treatment with MEVACOR were consistent across men and women, smokers an ...
Protocol S1.
Protocol S1.

... at the Data Management Center via e-mail [[email protected] for sites in the U.S. (ACTUs) or [email protected] for sites outside the U.S. (ICTUs)] to have the relevant personnel at the site added to the actg.protA5164 e-mail group as soon as possible. Inclusion in the protocol e-mail ...
Protocol S1.
Protocol S1.

... condom use has been shown to prevent HIV-1 transmission [4], but women are often unable to negotiate the use of condoms by their male partners [5-7]. The female condom has recently been marketed as an alternative barrier method [6], but use of this device requires a certain level of skill, and at le ...
A 76-Year-Old Man With Macular Degeneration
A 76-Year-Old Man With Macular Degeneration

... Age-related macular degeneration is associated with certain risk factors that may provide insight into its origins as well as allow for risk modification. These factors include age,2 family history,29 race,30 smoking,31-33 hypertension,34-38 atherosclerosis,38 inflammation,21,22 obesity,39 consumpti ...
Omnibus Codes - UnitedHealthcareOnline.com
Omnibus Codes - UnitedHealthcareOnline.com

... This Medical Policy provides assistance in interpreting UnitedHealthcare benefit plans. When deciding coverage, the member specific benefit plan document must be referenced. The terms of the member specific benefit plan document [e.g., Certificate of Coverage (COC), Schedule of Benefits (SOB), and/o ...
Chronic Pruritus
Chronic Pruritus

... low concentrations (1 to 5%); higher concentrations tend to cause irritation.27 The long-term use of this agent for chronic itch has not been studied. ...
Efficacy of methotrexate to prevent postoperative recurrence of Crohn’s disease
Efficacy of methotrexate to prevent postoperative recurrence of Crohn’s disease

... AIMS: to determine the efficacy and safety of MTX to prevent endoscopic and clinical POR at 24 weeks after surgery in low risk patients. METHODS: the study consists on a multicenter, randomized, double-blind and placebocontrolled clinical trial that will enroll 132 patients at low risk for POR (non- ...
Medical Examinations
Medical Examinations

... But when well written, A-type less often forces the writer to deal with isolated facts ...
Medical Examinations
Medical Examinations

... But when well written, A-type less often forces the writer to deal with isolated facts ...
Medicines Management Programme Preferred Drugs Calcium
Medicines Management Programme Preferred Drugs Calcium

... Second generation DHP CCBs were developed in order to improve the pharmacokinetic profile and reduce the unwanted side effects of first generation CCBs, with a longer duration of action and enhanced vascular selectivity.13 There are two subclasses of CCBs in this group, the first (subclass A) compri ...
Biomedical Consent Template
Biomedical Consent Template

... This research study is a Phase I clinical trial, which tests the safety of an investigational [drug//device/intervention] and also tries to define the appropriate dose of the investigational [drug/device/intervention] to use for further studies. “Investigational” means that the [drug/device/interven ...
Dapoxetine for Premature Ejaculation Mon Jan 14 2013
Dapoxetine for Premature Ejaculation Mon Jan 14 2013

... serotonin reuptake inhibitors (SSRIs) is common, effective and safe. Development and regulatory approval of drugs specifically for the treatment of PE will reduce reliance on off-label treatments and serve to fill an unmet treatment need. The objective of this article is to review evidence supportin ...
ICD-10 : Interactive Training Guide
ICD-10 : Interactive Training Guide

... is better for physicians to provide more rather than less. ...
A New Option in the Medical Management of Premature Ejaculation
A New Option in the Medical Management of Premature Ejaculation

... inhibitors (SSRIs) is common, effective and safe. Development and regulatory approval of drugs specifically for the treatment of PE will reduce reliance on off-label treatments and serve to fill an unmet treatment need. The objective of this article is to review evidence supporting the efficacy and ...
in the high court of kano state holden at kano suit no
in the high court of kano state holden at kano suit no

... It would be disingenuous to ignore the significant humanitarian aspect of the Defendants’ intervention. The Defendants believed Trovan could save lives. It was the Defendants’ hope that this new drug would significantly reduce the cost of care and improve the treatment and health of patients in epid ...
Ongoing Clinical Trials Posters II
Ongoing Clinical Trials Posters II

... Author Block: Raul Nogueira, Emory Univ, Atlanta, GA; Tudor Jovin, UPMC, Pittsburgh, PA; DAWN Trial Investigators Abstract Body: Background: Whether the treatment window for endovascular therapy can be expanded in properly selected patients remains to be established. Objective: To evaluate the hypot ...
Passionflower: A review of research and clinical
Passionflower: A review of research and clinical

... Passifloraceae. Passiflora incarnata and P. alata, also commonly known as Passionflower, are two species of a perennial climbing vine with beautiful exotic flowers and delicious fruit that grow worldwide, preferring subtropical, frost-free climates. They are native to the tropical and semi-tropical ...
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Clinical trial

Clinical trials are experiments done in clinical research. Such prospective biomedical or behavioral research studies on human participants are designed to answer specific questions about biomedical or behavioral interventions, including new treatments (such as novel vaccines, drugs, dietary choices, dietary supplements, and medical devices) and known interventions that warrant further study and comparison. Clinical trials generate data on safety and efficacy. They are conducted only after they have received health authority/ethics committee approval in the country where approval of the therapy is sought. These authorities are responsible for vetting the risk/benefit ratio of the trial - their approval does not mean that the therapy is 'safe' or effective, only that the trial may be conducted.Depending on product type and development stage, investigators initially enroll volunteers and/or patients into small pilot studies, and subsequently conduct progressively larger scale comparative studies. Clinical trials can vary in size and cost, and they can involve a single research center or multiple centers, in one country or in multiple countries. Clinical study design aims to ensure the scientific validity and reproducibility of the results.Trials can be quite costly, depending on a number of factors. The sponsor may be a governmental organization or a pharmaceutical, biotechnology or medical device company. Certain functions necessary to the trial, such as monitoring and lab work, may be managed by an outsourced partner, such as a contract research organization or a central laboratory.Only 10% of all drugs started in human clinical trials become an approved drug.
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