File
... • H1 blockers are competitive pharmacologic antagonists at H1receptor, these drugs have no effect on histamine release from storage sites. Because their structure closely resembles that of muscarinic blockers and alpha blockers, many of these agents are also pharmacologic antagonists at these recept ...
... • H1 blockers are competitive pharmacologic antagonists at H1receptor, these drugs have no effect on histamine release from storage sites. Because their structure closely resembles that of muscarinic blockers and alpha blockers, many of these agents are also pharmacologic antagonists at these recept ...
Anti-platelets
... • Cyclic peptide inhibitor of the fibrinogen binding site on GpIIb/IIIa receptor • Short duration of action: 6-12 hrs • Given with aspirin and heparin • Use: – Acute coronary syndrome – Angioplastic coronary interventions • Adverse effects: – Bleeding (10%) – Thrombocytopenia (0.5-1%) 3) Tirofiban • ...
... • Cyclic peptide inhibitor of the fibrinogen binding site on GpIIb/IIIa receptor • Short duration of action: 6-12 hrs • Given with aspirin and heparin • Use: – Acute coronary syndrome – Angioplastic coronary interventions • Adverse effects: – Bleeding (10%) – Thrombocytopenia (0.5-1%) 3) Tirofiban • ...
Draft Version 1 Iraqi Hypertension Guidelines 2016 / Iraqi
... If hypertension is not diagnosed but there is evidence of target organ damage such as left ventricular hypertrophy, albuminuria or proteinuria, consider carrying out investigations for alternative causes of the target organ damage. If hypertension is not diagnosed, measure the person's clinic blood ...
... If hypertension is not diagnosed but there is evidence of target organ damage such as left ventricular hypertrophy, albuminuria or proteinuria, consider carrying out investigations for alternative causes of the target organ damage. If hypertension is not diagnosed, measure the person's clinic blood ...
Infusion therapy in severe heart failure. A reappraisal
... Milrinone. This drug is characterized by a long half-life (20 to 45 min) and the therapeutic regimen generally includes a bolus of 50 µg/kg given over 10-20 min followed by a constant infusion of 0.375 to 0.75 µg/kg/ min20. In earlier studies milrinone showed favorable effects on survival in patient ...
... Milrinone. This drug is characterized by a long half-life (20 to 45 min) and the therapeutic regimen generally includes a bolus of 50 µg/kg given over 10-20 min followed by a constant infusion of 0.375 to 0.75 µg/kg/ min20. In earlier studies milrinone showed favorable effects on survival in patient ...
Drugs acting on RAAS by Dr Vignesh S
... ARBs - well tolerated in patients who are intolerant of ACEIused in symptomatic and asymptomatic pts of HFrEF <40% who are ACE-intolerant for reasons other than hyperkalemia or renal insufficiency As with ACEI, ARBs should also be initiated in low doses, uptitrated every 3-5 days, and BP,RFT,Potassi ...
... ARBs - well tolerated in patients who are intolerant of ACEIused in symptomatic and asymptomatic pts of HFrEF <40% who are ACE-intolerant for reasons other than hyperkalemia or renal insufficiency As with ACEI, ARBs should also be initiated in low doses, uptitrated every 3-5 days, and BP,RFT,Potassi ...
Headache in Mild-to-Moderate Hypertension and Its
... Patients were men or women (surgically sterile or postmenopausal) 18 years or older (irbesartan therapy, n=1987; placebo, n= 686). All patients had newly discovered or established mild-to-moderate hypertension (defined as seated diastolic BP of 95-110 mm Hg) and were randomly assigned to a treatment ...
... Patients were men or women (surgically sterile or postmenopausal) 18 years or older (irbesartan therapy, n=1987; placebo, n= 686). All patients had newly discovered or established mild-to-moderate hypertension (defined as seated diastolic BP of 95-110 mm Hg) and were randomly assigned to a treatment ...
Ken`s PowerPoint Slides
... In adults with hypertension, does treatment with antihypertensive pharmacologic therapy to a specified BP goal lead to improvements in health ...
... In adults with hypertension, does treatment with antihypertensive pharmacologic therapy to a specified BP goal lead to improvements in health ...
Angiotensin Receptor Blockers and Aldosterone Antagonists in
... inhibitors seems to mediate two important side effects of this class of compounds, that is, cough and angioedema. These side effects would be reduced if angiotensin converting enzyme remains intact and angiotensin II blockade is maintained at the receptor level. However, it also appears that the acc ...
... inhibitors seems to mediate two important side effects of this class of compounds, that is, cough and angioedema. These side effects would be reduced if angiotensin converting enzyme remains intact and angiotensin II blockade is maintained at the receptor level. However, it also appears that the acc ...
PRODUCT MONOGRAPH
... In cases where cyanosis should develop during high-dose treatment, work-up must include search for methemoglobinemia. Cardiovascular Nitroglycerin is a potent vasodilator and causes a slight decrease in mean blood pressure (approximately 10-15 mmHg) in some patients when used in therapeutic dosages. ...
... In cases where cyanosis should develop during high-dose treatment, work-up must include search for methemoglobinemia. Cardiovascular Nitroglycerin is a potent vasodilator and causes a slight decrease in mean blood pressure (approximately 10-15 mmHg) in some patients when used in therapeutic dosages. ...
preclinical evaluation of central nervous system stimulant agents
... Central nervous system (CNS) stimulants are agents that speed up physical and mental processes. The middle of the 20th centuries identifies a pivotal period in the treatment of mentally ill. Since the 1950's the development of psychopharmacology has expanded to include wide spread use of antipsychot ...
... Central nervous system (CNS) stimulants are agents that speed up physical and mental processes. The middle of the 20th centuries identifies a pivotal period in the treatment of mentally ill. Since the 1950's the development of psychopharmacology has expanded to include wide spread use of antipsychot ...
pharm chapter 21 [9-2
... when NO inhalation therapy stopped o NTG has short half-life (about 5 minutes) after which it is denitrated into biologically active glyceryl dinitrate metabolites that have longer half-lives (about 40 minutes) o Equivalent doses of isosorbide dinitrate can be more effective than NTG because isosorb ...
... when NO inhalation therapy stopped o NTG has short half-life (about 5 minutes) after which it is denitrated into biologically active glyceryl dinitrate metabolites that have longer half-lives (about 40 minutes) o Equivalent doses of isosorbide dinitrate can be more effective than NTG because isosorb ...
An Overview of the FDA Pregnancy and Lactation Labeling Rule
... Failed to provide meaningful clinical information about drug exposure ...
... Failed to provide meaningful clinical information about drug exposure ...
3) Antihypertensive Drugs (Cont`d)
... – As a result, Ca enters the cell in exchange for Na, causing additional Ca to be released from intracellular binding sites – With the increase in intracellular concentration of free Ca ions, more Ca is available to activate the contractile proteins, ...
... – As a result, Ca enters the cell in exchange for Na, causing additional Ca to be released from intracellular binding sites – With the increase in intracellular concentration of free Ca ions, more Ca is available to activate the contractile proteins, ...
Adreno-cortico-steroids, Inhibitors, and Antagonists
... The synthetic analogs are generally preferable to natural steroids because of their negligible sodium-retaining effects. ...
... The synthetic analogs are generally preferable to natural steroids because of their negligible sodium-retaining effects. ...
management of hypertension in diabetes
... Writing Group of American Society for Hypertension (WG-ASH) describes it as a complex cardiovascular disorder rather than just blood pressure values. It characterizes the disease as a progressive cardiovascular syndrome with many causes that result in both functional and structural changes in the he ...
... Writing Group of American Society for Hypertension (WG-ASH) describes it as a complex cardiovascular disorder rather than just blood pressure values. It characterizes the disease as a progressive cardiovascular syndrome with many causes that result in both functional and structural changes in the he ...
Results of clinical trials with diuretics in heart failure - Heart
... Asymptomatic left ventricular dysfunction and the clinical syndrome of overt heart failure therefore involve a very different physiological state even though there is obviously a considerable overlap between the two conditions. There is no reason to suppose that both can be improved by the same drug ...
... Asymptomatic left ventricular dysfunction and the clinical syndrome of overt heart failure therefore involve a very different physiological state even though there is obviously a considerable overlap between the two conditions. There is no reason to suppose that both can be improved by the same drug ...
Protein Ligand Interactions: A Method and its Application to Drug Discovery
... • The truth is we know very little about how the major drugs we take work – receptors are unknown • We know even less about what side effects they might have - receptors are unknown • Drug discovery seems to be approached in a very consistent and conventional way • The cost of bringing a drug to mar ...
... • The truth is we know very little about how the major drugs we take work – receptors are unknown • We know even less about what side effects they might have - receptors are unknown • Drug discovery seems to be approached in a very consistent and conventional way • The cost of bringing a drug to mar ...
Benzodiazepine Metabolism and Pharmacokinetics
... States. 1,2 In 2008, approximately 5.2% of US adults (18-80 years old) have used benzodiazepines, and the percentage increases with age.1 Benzodiazepine core chemical structure is composed of diazepine fused to a benzene ring. Different benzodiazepines have different side chains, which determine the ...
... States. 1,2 In 2008, approximately 5.2% of US adults (18-80 years old) have used benzodiazepines, and the percentage increases with age.1 Benzodiazepine core chemical structure is composed of diazepine fused to a benzene ring. Different benzodiazepines have different side chains, which determine the ...
Drugs Used In Pregnancy
... Has been associated with fetal growth retardation in several uncontrolled studies And one small trial. In most studies, the causal nature of the association was Unclear either because multiple agents were administered simultaneously or because of inability to separate effects of the mother's underl ...
... Has been associated with fetal growth retardation in several uncontrolled studies And one small trial. In most studies, the causal nature of the association was Unclear either because multiple agents were administered simultaneously or because of inability to separate effects of the mother's underl ...
Mechanisms and Clinical Consequences of Heart Failure
... Supraventricular premature complex Supraventricular tachycardia Ventricular tachycardia Ventricular fibrillation ...
... Supraventricular premature complex Supraventricular tachycardia Ventricular tachycardia Ventricular fibrillation ...
Histamine receptor antagonists
... have significant activity in preventing motion sickness. They are less effective against an episode of motion sickness already present. 3. Antiparkinsonism effects—Some of the H1 antagonists, especially diphenhydramine, have significant acute suppressant effects on the extrapyramidal symptoms associ ...
... have significant activity in preventing motion sickness. They are less effective against an episode of motion sickness already present. 3. Antiparkinsonism effects—Some of the H1 antagonists, especially diphenhydramine, have significant acute suppressant effects on the extrapyramidal symptoms associ ...
practical approach to medical management of glaucoma
... ahead for treatment and regular follow up. • Give time to your glaucoma patient. • Praise the lower IOP value in follow up visits and the effort he/she has put in taking the treatment. ...
... ahead for treatment and regular follow up. • Give time to your glaucoma patient. • Praise the lower IOP value in follow up visits and the effort he/she has put in taking the treatment. ...
Journal of Chemical and Pharmaceutical Research __________________________________________________
... ineffective if administered after symptoms have already appeared. Scopolamine is one of the most effective single agent in preventing vertigo. Anticholinergics have prominent side effects of dry mouth, dilated pupils, sedation, decreased alertness and impaired attention. Addiction and psychosis have ...
... ineffective if administered after symptoms have already appeared. Scopolamine is one of the most effective single agent in preventing vertigo. Anticholinergics have prominent side effects of dry mouth, dilated pupils, sedation, decreased alertness and impaired attention. Addiction and psychosis have ...