
Cannabinoid CB1 Receptor Antagonists as Promising New
... properties [intravenous drug self-administration, conditioned place preference (CPP), and intracranial self-stimulation procedures], the influence of environmental factors on drug-seeking behavior (CPP, second-order schedules of drug self-administration, reinstatement of extinguished drug-seeking be ...
... properties [intravenous drug self-administration, conditioned place preference (CPP), and intracranial self-stimulation procedures], the influence of environmental factors on drug-seeking behavior (CPP, second-order schedules of drug self-administration, reinstatement of extinguished drug-seeking be ...
Hypertension Medications
... Options and Progression of Treatment for Hypertension • Long-term success depends on patients understanding the characteristics and diseases that contribute to the issue Demographic characteristics – age, gender, race Coexisting diseases and risk factors – migraine headaches, dysrhythmias, angi ...
... Options and Progression of Treatment for Hypertension • Long-term success depends on patients understanding the characteristics and diseases that contribute to the issue Demographic characteristics – age, gender, race Coexisting diseases and risk factors – migraine headaches, dysrhythmias, angi ...
Using of medicine in clinical practice_1
... shoulder and down the arm, due to insufficient blood supply to the heart that is usually caused by coronary disease B. An often fatal form of arrhythmia characterized by rapid, irregular fibrillar twitching of the ventricles of the heart instead of normal contractions, resulting in a loss of pulse C ...
... shoulder and down the arm, due to insufficient blood supply to the heart that is usually caused by coronary disease B. An often fatal form of arrhythmia characterized by rapid, irregular fibrillar twitching of the ventricles of the heart instead of normal contractions, resulting in a loss of pulse C ...
Autonomic Pharmacology
... ACh also has a (-)'ve inotropic effect, whether applied directly or by vagal stimulation however this effect is smaller than that observed in the atrium and is more pronounced when contractility is enhanced by adrenergic stimulation automaticity is decreased and the threshold for VF is increased SNS ...
... ACh also has a (-)'ve inotropic effect, whether applied directly or by vagal stimulation however this effect is smaller than that observed in the atrium and is more pronounced when contractility is enhanced by adrenergic stimulation automaticity is decreased and the threshold for VF is increased SNS ...
View/Open
... DRUGS AFFECTING RENIN-ANGIOTENSIN SYSTEM AND PLASMA KININS involved in cognitive function and memory in animals. Thus Ang IV improves memory. Some vascular, renal and other peripheral effects of Ang IV have also been described. Angiotensin (1-7) This heptapeptide can be produced from Ang I or Ang II ...
... DRUGS AFFECTING RENIN-ANGIOTENSIN SYSTEM AND PLASMA KININS involved in cognitive function and memory in animals. Thus Ang IV improves memory. Some vascular, renal and other peripheral effects of Ang IV have also been described. Angiotensin (1-7) This heptapeptide can be produced from Ang I or Ang II ...
OVERVIEW
... the receptor than full agonist, the net effect will be less cumulative receptor activation. Therefore, the partial agonist will prevent the full agonist from binding the receptor and exerting a maximal response. The key point is that partial agonists are often used clinically to competitively inhibi ...
... the receptor than full agonist, the net effect will be less cumulative receptor activation. Therefore, the partial agonist will prevent the full agonist from binding the receptor and exerting a maximal response. The key point is that partial agonists are often used clinically to competitively inhibi ...
Anticholinergics for Overactive Bladder Therapy: Central Nervous
... The mainstay of pharmacological treatment of overactive bladder (OAB) is anticholinergic therapy using muscarinic receptor antagonists (tertiary or quaternary amines). Muscarinic receptors in the brain play an important role in cognitive function, and there is growing awareness that antimuscarinic O ...
... The mainstay of pharmacological treatment of overactive bladder (OAB) is anticholinergic therapy using muscarinic receptor antagonists (tertiary or quaternary amines). Muscarinic receptors in the brain play an important role in cognitive function, and there is growing awareness that antimuscarinic O ...
Anecortave Acetate for Steroid-Induced OHT
... Anecortave acetate is a cortisene, a synthetic molecule derived from cortisol acetate but devoid of glucocorticoid activity.6 Due to its angiostatic properties, the agent has been studied as a therapy for neovascular age-related macular degeneration.7 Preclinical safety pharmacology and toxicity stu ...
... Anecortave acetate is a cortisene, a synthetic molecule derived from cortisol acetate but devoid of glucocorticoid activity.6 Due to its angiostatic properties, the agent has been studied as a therapy for neovascular age-related macular degeneration.7 Preclinical safety pharmacology and toxicity stu ...
Chapter 17
... Practice Question #1 When teaching a patient who has been prescribed metoprolol (Lopressor) about side/adverse effects, which is the highest priority teaching point? A. B. C. D. ...
... Practice Question #1 When teaching a patient who has been prescribed metoprolol (Lopressor) about side/adverse effects, which is the highest priority teaching point? A. B. C. D. ...
Poster presentation
... methyldopa, short-acting nifedipine and reserpine. The interview sessions were audio taped and the transcripts transcribed by two researchers (independently). Results: Overall, participants were ambivalent about the hypertension treatment guidelines. They were not adverse to the general concept of g ...
... methyldopa, short-acting nifedipine and reserpine. The interview sessions were audio taped and the transcripts transcribed by two researchers (independently). Results: Overall, participants were ambivalent about the hypertension treatment guidelines. They were not adverse to the general concept of g ...
Ocular Toxicology and Pharmacology
... Important Drug-related Adverse Effects for the Ophthalmologist Marijuana: • Primary use: Recreational. Legal in some states for medicinal purposes (IOP lowering, appetite stimulant) • Clinical concerns: The same cannabinols that lower IOP also cause CNS high. Other products are better at lowering I ...
... Important Drug-related Adverse Effects for the Ophthalmologist Marijuana: • Primary use: Recreational. Legal in some states for medicinal purposes (IOP lowering, appetite stimulant) • Clinical concerns: The same cannabinols that lower IOP also cause CNS high. Other products are better at lowering I ...
... cirrhosis and portal hypertension caused a marked fall in portal pressure, a reduction in hepatic blood flow, cardiac output and mean arterial blood pressure, but no additional change in azygos blood flow. The additional effect of isosorbide mononitrate was especially evident in patients whose porta ...
Pediatric Parenteral Nutrition
... ¾ Has a role in sedation for imaging, short procedures (Sedation-trained personnel should be involved with administration) ¾ NOT recommended for pediatric ICU sedation ¾ Associated with propofol infusion syndrome ¾ Monitor BP, HR, RR ¾ Green urine, may burn if given peripherally ...
... ¾ Has a role in sedation for imaging, short procedures (Sedation-trained personnel should be involved with administration) ¾ NOT recommended for pediatric ICU sedation ¾ Associated with propofol infusion syndrome ¾ Monitor BP, HR, RR ¾ Green urine, may burn if given peripherally ...
Anticoagulants, Thrombolytics Agents and Antiplatelet Drugs
... platelet aggregation on the first day, and inhibition reaches steady state between Day 3 and Day 7. Platelet aggregation and bleeding time gradually return to baseline values after treatment is discontinued, generally in about 5 days. ...
... platelet aggregation on the first day, and inhibition reaches steady state between Day 3 and Day 7. Platelet aggregation and bleeding time gradually return to baseline values after treatment is discontinued, generally in about 5 days. ...
Document
... are associated with the simultaneous production of two heart sounds during periods of atrioventricular disassociation. Ventricular tachycardia can be uniform (regular rhythm) or multiform (irregular rhythm). Multiform ventricular tachycardia is associated with more rapidly progressive signs of conge ...
... are associated with the simultaneous production of two heart sounds during periods of atrioventricular disassociation. Ventricular tachycardia can be uniform (regular rhythm) or multiform (irregular rhythm). Multiform ventricular tachycardia is associated with more rapidly progressive signs of conge ...
Atropine
... diaphragmatic contractions resume first. Depolarizing agents produce fascilations, lasting few second before inducing flaccid paralysis, but fascilations are not prominent in well anaesthezed patients. The action of SCh develops very rapidly. Apnoea occurs within 45–90 sec, but lasts only 2–5 min an ...
... diaphragmatic contractions resume first. Depolarizing agents produce fascilations, lasting few second before inducing flaccid paralysis, but fascilations are not prominent in well anaesthezed patients. The action of SCh develops very rapidly. Apnoea occurs within 45–90 sec, but lasts only 2–5 min an ...
Gram-Negative
... Led to contraindication in pediatric patients and pregnant or breastfeeding women Risk versus benefit ...
... Led to contraindication in pediatric patients and pregnant or breastfeeding women Risk versus benefit ...
Medicines Management Programme Preferred Drugs Calcium
... nifedipine slow-release (SR) or gastrointestinal therapeutic system (GITS).15,16 The second (subclass B) is comprised of chemical entities which have less negative effect on myocardial contractility and heart rate and reduced effect on atrioventricular conduction (e.g. nilvadipine).18 In clinical tr ...
... nifedipine slow-release (SR) or gastrointestinal therapeutic system (GITS).15,16 The second (subclass B) is comprised of chemical entities which have less negative effect on myocardial contractility and heart rate and reduced effect on atrioventricular conduction (e.g. nilvadipine).18 In clinical tr ...
No Slide Title
... a) Increasing the hydrophilicity of substituents allows the identification of an optimum value for p (Sp = -5). The equation is now parabolic (-0.034 (Sp)2) b) The optimum value of Sp is very low and implies a hydrophilic binding site c) R-5 implies that resonance effects are important at position 5 ...
... a) Increasing the hydrophilicity of substituents allows the identification of an optimum value for p (Sp = -5). The equation is now parabolic (-0.034 (Sp)2) b) The optimum value of Sp is very low and implies a hydrophilic binding site c) R-5 implies that resonance effects are important at position 5 ...
Cholinergic and Adrenergic Tones in the Control of Heart Rate
... Being so, there is no need to compensate for reflex changes in heart rate associated with hypertensive effects (24). The effects are also long lasting, and preliminary studies showed no substantial recovery in vagal tone after 24 hr in S. aurata or L. bergylta. Beta-adrenergic antagonists are known ...
... Being so, there is no need to compensate for reflex changes in heart rate associated with hypertensive effects (24). The effects are also long lasting, and preliminary studies showed no substantial recovery in vagal tone after 24 hr in S. aurata or L. bergylta. Beta-adrenergic antagonists are known ...
Antifungal Therapy During Pregnancy
... Imidazoles are the other commonly used topical agents for treatment of yeast vaginitis. In the studies comparing imidazoles to nystatin, imidazoles have uniformly superior cure rates and lower relapse rates [32, 33, 35, 37, 38]. In a study of volunteers, 1.4% of the topical vaginal dose of miconazol ...
... Imidazoles are the other commonly used topical agents for treatment of yeast vaginitis. In the studies comparing imidazoles to nystatin, imidazoles have uniformly superior cure rates and lower relapse rates [32, 33, 35, 37, 38]. In a study of volunteers, 1.4% of the topical vaginal dose of miconazol ...
Use of Herbal Products and Potential
... adverse reactions because of its effect on drug metabolism; it induces the hepatic cytochrome P450 system (8), particularly CYP3A4, an enzyme involved in oxidative metabolism ...
... adverse reactions because of its effect on drug metabolism; it induces the hepatic cytochrome P450 system (8), particularly CYP3A4, an enzyme involved in oxidative metabolism ...
Diuretics
... Elimination unchanged in kidney Variable elimination kinetics and therefore variable half-lives of elimination ranging from hours to days. ...
... Elimination unchanged in kidney Variable elimination kinetics and therefore variable half-lives of elimination ranging from hours to days. ...
Effects of the putative dopamine D receptor antagonist PNU 99194A
... isolated C57BLr6J mouse and a nonaggressive conspecific. In mice habituated to the activity chamber prior to drug administration, PNU 99194A increased locomotion and rearing at lower doses Ž5, 10 mgrkg. whereas higher doses Ž20, 30 mgrkg. reduced these behaviors early in the test session. Thigmotaxi ...
... isolated C57BLr6J mouse and a nonaggressive conspecific. In mice habituated to the activity chamber prior to drug administration, PNU 99194A increased locomotion and rearing at lower doses Ž5, 10 mgrkg. whereas higher doses Ž20, 30 mgrkg. reduced these behaviors early in the test session. Thigmotaxi ...
PDF Format - Indian Pediatrics
... Hydralazine: It is a non ACEi peripheral vasodilator, resulting in relaxation of arterial smooth muscles. Hydralazine does not produce hyperkalemia, and is safe in patients with renal impairment. It should be used in patients in whom ACEi or ARB are not tolerated or are contraindicated. Dose is 0.75 ...
... Hydralazine: It is a non ACEi peripheral vasodilator, resulting in relaxation of arterial smooth muscles. Hydralazine does not produce hyperkalemia, and is safe in patients with renal impairment. It should be used in patients in whom ACEi or ARB are not tolerated or are contraindicated. Dose is 0.75 ...