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Autofluorescence Imaging and Spectroscopy of Human Lung Cancer
Autofluorescence Imaging and Spectroscopy of Human Lung Cancer

... examination to differentiate normal bronchus mucosa from malignant lesions [15,20]. Fawzy et al. differentiated bronchial cancerous lesions with fluorescence spectroscopy, and reached a sensitivity and specificity of 71% and 74% [21]. Most of bronchoscopes measured the decrease of autofluorescence i ...
Unusual Abscesses Associated with Colon Cancer: Report of Three
Unusual Abscesses Associated with Colon Cancer: Report of Three

... diagnosed intraoperatively. The cancer recurred in cases I and III. We emphasize that precise surgical evaluation has an important role in the diagnosis of these complicated diseases. In addition, surgery affords the patient the best chance of recovery, and in these advanced cases radical treatment i ...
Use of Imputed Population-based Cancer Registry Data as a
Use of Imputed Population-based Cancer Registry Data as a

... of the relation between ER+ breast cancer and the use of hormone replacement therapy. As use of hormone replacement therapy has declined in the population, so have the rates of ER+ breast cancer (2). Treatment and prognosis also differ by ER status, and rates of ER+ disease vary by race. As a result ...
A Population Genetic Perspective on Tumor
A Population Genetic Perspective on Tumor

... may be restricted to certain tumor regions or more pervasive, but as these events initially occur in a single cell, they only become detectable after subsequent rounds of cell division or as a result of a clonal expansion. As discussed in subsequent sections, multiple factors influence the ability to ...
Dataset for histopathology reporting of salivary gland neoplasms
Dataset for histopathology reporting of salivary gland neoplasms

... of recurrence and for survival, and varies between primary tumour types and sites. To keep the guidance relatively simple, not all possible variations are described in detail and the reader is referred to the cited literature for more information. The core set of data items for salivary malignancies ...
Thec.470 T > C CHEK2missense variant increases the risk of
Thec.470 T > C CHEK2missense variant increases the risk of

... differentiated thyroid carcinoma are reported in Poland each year (2389 cases in 2011) [1]. The majority of patients are women. Generally, in various populations thyroid cancer occurs approximately four to six times less frequently in males, which indicates different molecular backgrounds between th ...
Disease-specific genomic analysis: identifying the signature of
Disease-specific genomic analysis: identifying the signature of

... High dimensional data like microarray expression, SNP, array CGH and proteomic data have been used to study a wide range of problems aimed at achieving a deeper and more global understanding of diseases. Identification of expression relevant to the biological problem being studied can however be a d ...
Testicular metastasis from prostate carcinoma are rare despite the
Testicular metastasis from prostate carcinoma are rare despite the

... Metastasis to testis are most commonly from the prostate, lung, colon, stomach,melanoma, and kidney. Increased dectection of testicular metastasis from prostate carcinoma can be explained by orchiectomy done for prostate carcinoma. 3,4,11,12,13 Semans in 1938 reported the first case of prostatic ca ...
Induction of VX2 para-renal carcinoma in rabbits: generation of
Induction of VX2 para-renal carcinoma in rabbits: generation of

... easy propagation in the skeletal muscle, represent its features [1-4]. It is of note that this model has been used to model various types of cancer, including those of pancreas, kidney and liver [5,15]. The transplantation of VX2 cells can be achieved either by implanting solid tumor pieces or by in ...
Diagnostic and Prognostic MicroRNAs in Stage II Colon Cancer
Diagnostic and Prognostic MicroRNAs in Stage II Colon Cancer

... plotted according to Kaplan-Meier. Univariate analysis was performed using the log-rank test. Multivariate analysis was performed using the Cox proportional hazards regression model. The software used for survival analysis was STATA 9.2 (StataCorp). Construction of predictive biomarkers based on miR ...
High-resolution analysis of DNA copy number
High-resolution analysis of DNA copy number

... (CGH) allows for high throughput, high-resolution genomewide screening of DNA copy number changes in solid tumors (6--8). Copy number alterations detected by array-based CGH can be directly related to sequence information to aid in the localization, identification and validation of cancer causing ge ...
Cancer Registry Specialty Track HIM Curriculum
Cancer Registry Specialty Track HIM Curriculum

... Specialty Track Student Learning Outcomes and curricular considerations are derived from the NCRA website and staff. They are generally at a higher taxonomic level than similar learning outcomes from the associate level curriculum competencies as the intent of the specialty track is to build on the ...
Copyright Information of the Article Published Online TITLE CpG
Copyright Information of the Article Published Online TITLE CpG

... phenotype (CIMP)[5]. In this commentary, we discuss the classification and functional ramifications of CIMP across four types of gastrointestinal adenocarcinomas (esophageal, gastric, colon and rectal), using data from The Cancer Genome Atlas (TCGA) to address lingering questions and identify novel ...
Antar Labeeb EL Sheikh Aly Prof. Dr. / Ibrahim Mohamed El Ghazawy
Antar Labeeb EL Sheikh Aly Prof. Dr. / Ibrahim Mohamed El Ghazawy

... factors for cancer among patients with inflammatory bowel disease (IBD) include the younger age at diagnosis, greater extent, and duration of disease, increased severity of inflammation and family history of colorectal cancer. Recent evidence suggests that current medical therapies and surgical tech ...
Strategic Management Plan
Strategic Management Plan

... and other cancer surveillance organizations in all U.S. states and Canadian provinces; leading federal agencies, including the U.S. Centers for Disease Control and Prevention (CDC) and the National Cancer Institute (NCI); Canadian partner organizations, including the Canadian Council of Cancer Regis ...
Semiautomated primary tumor volume measurements by dynamic
Semiautomated primary tumor volume measurements by dynamic

... observers. In 1997, Rasch et al18 showed that MRIderived GTVs have less interobserver variation than CT-derived GTV. Furthermore, all studies showing the prognostic significance of tumor volume used delineated volumes determined on radiology. Therefore, we believe that MRI delineation by 1 observer ...
Carbohydrate-Containing Molecules as Potential Biomarkers
Carbohydrate-Containing Molecules as Potential Biomarkers

... from every patient (%, relative peak area) are shown in Supplementary Table S1 (for CS/DS) and Supplementary Table S2 (for HS) (Supplementary Material is available online at www.liebertpub.com). Despite some observed differences between normal and cancer tissue groups, it is unclear whether these di ...
case report primary papillary adenocarcinoma of vagina: a rare case
case report primary papillary adenocarcinoma of vagina: a rare case

... stage III primary papillary adenocarcinoma of vagina. As most of the adenocarcinoma of vagina is metastatic, the possibility of primary papillary adenocarcinoma of vagina has to be kept in mind. The present case was successfully treated with chemotherapy and radiotherapy, suggesting that chemoradiat ...
| Lung adenocarcinoma expression profile: one more layer of heterogeneity Elisabeth Brambilla
| Lung adenocarcinoma expression profile: one more layer of heterogeneity Elisabeth Brambilla

... We would have expected a BC signature corresponding to a typical basal airway cell to be more efficient in distinguishing subtypes of squamous cell carcinoma, which is not the case since the authors themselves recognise that the signature is shared by all squamous cell carcinoma because of their com ...
Squamous Cell Carcinoma - CEConnection
Squamous Cell Carcinoma - CEConnection

... risk and are identified by their location. The three main forms are oral, plantar, and Buschke-Loewenstein tumors (Lohmann & Solomon, 2001). Lymphoepithelioma-like carcinoma is a rare form of squamous cell carcinoma, recently classified by the World Health Organization. Its histogenesis is as yet un ...
a report on rare case of carcinoma fallopian tube
a report on rare case of carcinoma fallopian tube

... INTRODUCTION: Fallopian tube carcinoma is the most uncommon carcinoma of the mullerian system, accounting for 3.6 cases per million women per year [1]. This rarity has prevented prospective trials that could answer questions of optimal treatment and prognostic factors. Only through large retrospecti ...
female breast - Cancer Research
female breast - Cancer Research

... I n 1893, forty-one years ago, I assisted Dr. Halstecl in exploring a clinically benign tumor of the breast. The patient was sixty-seven years of age and had observed a small tumor for about eleven months. It was our custom then to cut into the tumor and decide on its pathological nature from the na ...
Basal-Cell Carcinoma
Basal-Cell Carcinoma

... Five-year cure rates of 95 percent or higher are possible with the use of either curettage and electrodesiccation or cryosurgery for low-risk lesions — that is, small, well-defined primary lesions on the neck, trunk, and arms and legs, with nonaggressive histologic features. Curettage and electrodes ...
Periampullary cancer, in Cameron JL (ed): Current Surgical Therapy
Periampullary cancer, in Cameron JL (ed): Current Surgical Therapy

... Neoadjuvant therapy – is not routinely performed – used when the tumor appears locally invasive – Downstaging in about 10% of cases which allows for resection ...
Basal Cell Carcinoma
Basal Cell Carcinoma

... and BCC. Four hundred and fifty four people with two types of basal cell carcinoma were interviewed. Statistics were developed which concluded with a 95% confidence interval that smoking and BCC are not related (Hertog, 2001). Clinical Manifestations BCC is most commonly found in the head and neck r ...
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The Cancer Genome Atlas

The Cancer Genome Atlas (TCGA) is a project, begun in 2005, to catalogue genetic mutations responsible for cancer, using genome sequencing and bioinformatics. TCGA represents an effort in the War on Cancer that is applying high-throughput genome analysis techniques to improve our ability to diagnose, treat, and prevent cancer through a better understanding of the genetic basis of this disease.TCGA is supervised by the National Cancer Institute and the National Human Genome Research Institute funded by the US government. A three-year pilot project, begun in 2006, focused on characterization of three types of human cancers: glioblastoma multiforme, lung, and ovarian cancer. In 2009, it expanded into phase II, which plans to complete the genomic characterization and sequence analysis of 20-25 different tumor types by 2014. Funding is split between genome characterization centers (GCCs), which perform the sequencing, and genome data analysis centers (GDACs), which perform the bioinformatic analyses.The project scheduled 500 patient samples, more than most genomics studies, and used different techniques to analyze the patient samples. Techniques gene expression profiling, copy number variation profiling, SNP genotyping, genome wide DNA methylation profiling, microRNA profiling, and exon sequencing of at least 1,200 genes. The TCGA is sequencing the entire genomes of some tumors, including at least 6,000 candidate genes and microRNA sequences. This targeted sequencing is being performed by all three sequencing centers using hybrid-capture technology. In phase II, TCGA is performing whole exon sequencing on 80% of the cases and whole genome sequencing on 80% of the cases used in the project.
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