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Recent Advances From Basic and Clinical Studies of Esophageal
Recent Advances From Basic and Clinical Studies of Esophageal

... esophagus, lungs, and salivary glands. (2) Extrinsic acetaldehyde derived from alcoholic beverages and foods (a) and that produced by oral microflora (b). Extrinsic acetaldehyde is believed to be associated with direct exposure to the esophageal epithelium. ...
1. Standard Demographics
1. Standard Demographics

... requirements have been identified predominantly from the CRS, with some additional requirements identified in the Standard NHS Contract for acute hospitals4. The business and information requirements will be presented as part of the Draft Stage submission. As part of the user guidance, the developer ...
Pathology Report: ERBB4 Expression in Ovarian Serous Carcinoma
Pathology Report: ERBB4 Expression in Ovarian Serous Carcinoma

... [IRs] to platinum-based therapy), 51 normal tissue controls, and 16 ovarian cancer cell lines. H scores were used to evaluate expression and were semiquantitatively classified into low, intermediate, and high categories. Category frequencies were compared between tumor specimens vs controls using an ...
Supplemental Information
Supplemental Information

... S1). The ultimate decisions for article inclusion/exclusion were made jointly between two of the authors (APS and RJK). Data abstraction and organization The following data was collected from all articles meeting our inclusion criteria: authors, journal, publication year, country, description of pat ...
LUNG CANCER. III. SCREENING, DIAGNOSIS AND STAGING
LUNG CANCER. III. SCREENING, DIAGNOSIS AND STAGING

... Screening. XIV. Computed tomography * while CT screening detects LC in 1 - 4% of screened pts over 5 - yr period, it also detects substantial no. of false+ lung lesions (25 to 75%) needing follow - up and evaluation; * appropriate management of these small lesions undefined; - unnecessary treatment ...
Ovary
Ovary

... Specify site(s): ____________________________ Summary of Organs/Tissues Microscopically Involved by Tumor (check all that apply) ___ One ovary ___ Both ovaries ___ Omentum ___ Uterus ___ Peritoneum ___ Other organs/tissues Specify all: ____________________________ *Venous/Lymphatic (Large/Small Vess ...
Is it cancer, doctor?
Is it cancer, doctor?

... provides prognostic information identifying those who may benefit from further surgery or adjuvant therapy ...
Unique microRNAprofiles in EGFRmutated lung
Unique microRNAprofiles in EGFRmutated lung

... microRNA expression and clinicopathological factors (sex, stage, age at surgery, adjuvant chemotherapy, smoking status, tumor size and EGFR- and KRAS-mutational status) with significant influence on progression-free survival. The Cox regression model was used for multivariate analyses. Factors include ...
MOLECULAR HOMOLOGY BETWEEN HUMAN AND DOG ON
MOLECULAR HOMOLOGY BETWEEN HUMAN AND DOG ON

... In the cancer genome, somatic mutations usually include base substitutions, insertions and deletions or structural variations (Helleday et al. 2014). The first report of cancer genome sequencing appeared in 2006 (Ley et al. 2008). In that study, 13,023 genes were sequenced in 11 breast and 11 colore ...
Metachronous carcinomas in colorectum and its clinicopathological
Metachronous carcinomas in colorectum and its clinicopathological

... polyposis and hyperplastic polyposis accounted for 2%, 4% and 2% of synchronous colorectal carcinoma [15]. In this study, ulcerative colitis and familial adenomatous polyposis were not found to be associated with metachronous colorectal carcinoma. It is likely that patients with these predisposing l ...
ovarian tumors
ovarian tumors

... SEROUS CYSTADENOMA A unilocular or multilocular cyst lined by epithelium similar to the fallopian tube. They are the most common benign epithelial tumors and form 20% of all ovarian neoplasm. In 10% of cases they are bilateral. It is uncommon to find them large than a fetal head. 2006-11-1 七年制 ...
Using semi-quantitative dynamic contrast
Using semi-quantitative dynamic contrast

... Abstract: Purpose: To test the feasibility of semi-quantitative dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) parameters for evaluating tumor hypoxia in a maxillofacial VX2 rabbit model. Methods: Eight New Zealand rabbits were inoculated with VX2 cell solution to establish a maxillo ...
Raman Spectroscopic Analysis of Blood, Urine, Saliva
Raman Spectroscopic Analysis of Blood, Urine, Saliva

... Background: Oral cancers are mostly being preceded by oral potentially malignant disorders (OPMD). Early diagnosis of oral cancer or OPMDs speed up treatment and improve prognosis. Raman spectroscopy of blood, urine, saliva and tissue samples collected from OPMD and oral cancer patients were compare ...
Magnification endoscopy in esophageal squamous cell carcinoma
Magnification endoscopy in esophageal squamous cell carcinoma

... cancer is the “pink-color” sign [16,17](Fig. 1A). This is readily identified as the “metallic silver” sign when it is seen with narrow-band imaging (NBI) enhancement [18](Fig.  1B). However, flat unstained areas smaller than 5 mm are usually not high-grade dysplasia. These can be disregarded during ...
Influence of NCI Cancer Center Attendance on Mortality in Lung
Influence of NCI Cancer Center Attendance on Mortality in Lung

... Our research contributes to the cancer control literature as well as to health care delivery and health policy literature. This work expands on previously demonstrated variation in outcomes for cancer patients in relation to the place of service. We augment the sparse literature with which we can un ...
Histopathology Reporting
Histopathology Reporting

... aware of significant pathology in other areas that might impact on their own specialization, e.g. metastatic carcinoma. Availability as PC-based templates also facilitates reporting, audit and download to cancer registries. • In immunohistochemistry there is an ever-expanding range of increasingly r ...
IOSR Journal of Dental and Medical Sciences (IOSR-JDMS)
IOSR Journal of Dental and Medical Sciences (IOSR-JDMS)

... registries have reported that the incidence of thyroid cancer is increasing 9-14. In our study, If we compare with all head and neck malignancy, out of 404 cases of head and neck malignancy registered in our Institute from January 2012 to December 2014,thyroid malignancy was found in 41 patients whi ...
Comparative Study of Metaplastic Breast Carcinoma and Triple
Comparative Study of Metaplastic Breast Carcinoma and Triple

... Nineteen (31.7%) patients experienced lymph node metastasis. In 19 patients with lymph node metastasis, the mean number of positive nodes was 2.4 (range, 1 to 11). Fourteen patients presented with American Joint Committee on Cancer (AJCC, 7th edition) stage IA, and 29 with stage IIA disease. Tumor s ...
Human papillomavirus genotypes distribution in 175
Human papillomavirus genotypes distribution in 175

... HPV18 (12.3%), HPV31 (8.8%), HPV33 (7.1%) and HPV35 (5.9%). Most infections (75%) were caused by individual HPV types. Women with adenocarcinoma were not younger than those with squamous cell carcinoma, as well, as women infected with HPV33 were older than those infected by other HPV types. Some dif ...
Dr. Rekha Patil N - journal of evidence based medicine and healthcare
Dr. Rekha Patil N - journal of evidence based medicine and healthcare

... atrophic seminiferous tubules along with malignant cells in groups and comado pattern. Cells had moderate amount of pale cytoplasm vesicular nuclei with prominent nucleolus. It was reported as metastasis of prostate adenocarcinoma in testis (Figure 2). An immunohistochemical prostate specific antige ...
Epithelial ovarian neoplasm
Epithelial ovarian neoplasm

... Prevention and Screening  Hereditary ovarian cancer – Genetic counseling and genetic testing for BRCA1and BRCA2. – Screening by transvaginal ultrasonography every 6 months for women wishing to preserve their reproductive capacity – Oral contraceptives for young women before they embark on an attem ...
Ovarian Cancer Biomarker Discovery Based on Genomic Approaches
Ovarian Cancer Biomarker Discovery Based on Genomic Approaches

... outcomes. Although the advancing proteomic technologies led to the discovery of numerous ovarian cancer biomarkers, no screening method has been recommended for early detection of ovarian cancer. Complexity and heterogeneity of ovarian carcinogenesis is a major obstacle to discover biomarkers. As ca ...
[pdf]
[pdf]

... saturation, and optical scattering coefficients in breast tissue. Recently, we developed a statistical image analysis technique for DOT [11] and applied it to a breast cancer data set [12]. The statistical approach derives a probability of malignancy signature for normal and cancerous tissues based ...
Significant Associations Between Driver Gene Mutations And DNA
Significant Associations Between Driver Gene Mutations And DNA

... peer-reviewed) is the author/funder. It is made available under a CC-BY-NC-ND 4.0 International license. ...
Dataset for the histological reporting of primary cutaneous basal cell
Dataset for the histological reporting of primary cutaneous basal cell

... Ideally, staging of basal cell carcinoma should be based on the latest published edition of the tumour, node and metastasis (TNM) categorisation of malignant tumours published by the International Union against Cancer (UICC).1 It has been internationally agreed that this should be identical to the s ...
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The Cancer Genome Atlas

The Cancer Genome Atlas (TCGA) is a project, begun in 2005, to catalogue genetic mutations responsible for cancer, using genome sequencing and bioinformatics. TCGA represents an effort in the War on Cancer that is applying high-throughput genome analysis techniques to improve our ability to diagnose, treat, and prevent cancer through a better understanding of the genetic basis of this disease.TCGA is supervised by the National Cancer Institute and the National Human Genome Research Institute funded by the US government. A three-year pilot project, begun in 2006, focused on characterization of three types of human cancers: glioblastoma multiforme, lung, and ovarian cancer. In 2009, it expanded into phase II, which plans to complete the genomic characterization and sequence analysis of 20-25 different tumor types by 2014. Funding is split between genome characterization centers (GCCs), which perform the sequencing, and genome data analysis centers (GDACs), which perform the bioinformatic analyses.The project scheduled 500 patient samples, more than most genomics studies, and used different techniques to analyze the patient samples. Techniques gene expression profiling, copy number variation profiling, SNP genotyping, genome wide DNA methylation profiling, microRNA profiling, and exon sequencing of at least 1,200 genes. The TCGA is sequencing the entire genomes of some tumors, including at least 6,000 candidate genes and microRNA sequences. This targeted sequencing is being performed by all three sequencing centers using hybrid-capture technology. In phase II, TCGA is performing whole exon sequencing on 80% of the cases and whole genome sequencing on 80% of the cases used in the project.
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