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Upper Gastrointestinal Bleeding as a Manifestation of Metastasis
... A 75-year-old white man presented to the emergency room (ER) with complaints of nausea, vomiting, and lower back pain for 1 day. His past medical history included peptic ulcer disease, prostate cancer status post radical prostatectomy in 2007, recent abdominal aortic aneurysmal (AAA) repair, and sta ...
... A 75-year-old white man presented to the emergency room (ER) with complaints of nausea, vomiting, and lower back pain for 1 day. His past medical history included peptic ulcer disease, prostate cancer status post radical prostatectomy in 2007, recent abdominal aortic aneurysmal (AAA) repair, and sta ...
a rare case of a patient with a metatypical basal cell carcinoma of
... Mohs micrographic surgery being an excellent surgical option having lower recurrence rates than classic excision [17]. Mohs is particularly indicated for high-risk locations such as the ears, midface, recurrent or large tumors, and tissue preser- ...
... Mohs micrographic surgery being an excellent surgical option having lower recurrence rates than classic excision [17]. Mohs is particularly indicated for high-risk locations such as the ears, midface, recurrent or large tumors, and tissue preser- ...
EphB2 Expression across 138 Human Tumor Types
... EphB2 expression in normal and neoplastic tissues. The results confirm the previously described high-level of EphB2 expression in normal colonic mucosa and expand these observations to show a significant association between loss of EphB2 expression and colorectal tumor progression. Furthermore, we a ...
... EphB2 expression in normal and neoplastic tissues. The results confirm the previously described high-level of EphB2 expression in normal colonic mucosa and expand these observations to show a significant association between loss of EphB2 expression and colorectal tumor progression. Furthermore, we a ...
Celgene Corporation, Dana-Farber Cancer Institute and University
... "The Myeloma Genome Project expects to lead the way towards developing personalized and targeted therapy to improve patient outcomes in myeloma," said Nikhil Munshi, M.D., Director of Basic and Correlative Science at the Jerome Lipper Multiple Myeloma Center at Dana-Farber Cancer Institute. The Myel ...
... "The Myeloma Genome Project expects to lead the way towards developing personalized and targeted therapy to improve patient outcomes in myeloma," said Nikhil Munshi, M.D., Director of Basic and Correlative Science at the Jerome Lipper Multiple Myeloma Center at Dana-Farber Cancer Institute. The Myel ...
Ovarian Cancer - SCBT-MR
... – Her2/Neu upregulated in clear cell carcinoma: may respond to anti- Her2/Neu antibody (Herceptin) therapy – Drugs aimed at MAPK/BRAF: ?Help in low-grade serous Ca Kurman RJ. Am J Surg Pathol 2010;34(3):433-443 ...
... – Her2/Neu upregulated in clear cell carcinoma: may respond to anti- Her2/Neu antibody (Herceptin) therapy – Drugs aimed at MAPK/BRAF: ?Help in low-grade serous Ca Kurman RJ. Am J Surg Pathol 2010;34(3):433-443 ...
Comprehensive Next-Generation Sequencing
... • The number of genomic alterations potentially treatable by targeted therapies is growing rapidly • Many of these targets are present in <10% of DNA in clinically relevant samples • A new paradigm for genomic testing is needed due to constraints of decreasing tissue amounts, increasing mutation num ...
... • The number of genomic alterations potentially treatable by targeted therapies is growing rapidly • Many of these targets are present in <10% of DNA in clinically relevant samples • A new paradigm for genomic testing is needed due to constraints of decreasing tissue amounts, increasing mutation num ...
Informatics for Population-based Cancer Surveillance
... surveillance and early case capture - Dependent upon hospital and provider EHRs - EHR often lacks fundamental cancer information such as diagnosis date, cancer site, histology, stage, treatment, biomarkers, and etc. ...
... surveillance and early case capture - Dependent upon hospital and provider EHRs - EHR often lacks fundamental cancer information such as diagnosis date, cancer site, histology, stage, treatment, biomarkers, and etc. ...
Print this article - Bengal Journal of Otolaryngology and Head Neck
... on top of some genetic contribution. This concept was introduced by Slaughter et al, who discovered that in oral cancers the epithelium beyond the boundaries of tumor possessed histologic changes resulting in wide array of premalignant diseases that give rise to multiple independent primary tumor.7 ...
... on top of some genetic contribution. This concept was introduced by Slaughter et al, who discovered that in oral cancers the epithelium beyond the boundaries of tumor possessed histologic changes resulting in wide array of premalignant diseases that give rise to multiple independent primary tumor.7 ...
PDF - Journal of Cancer Metastasis and Treatment
... target genetic mutations known to play critical roles in the progression to metastatic disease. EGFR mutation is one of the most common targetable mutations in NSCLC particularly in non squamous histology. The incidence of EGFR mutations in NSCLC varies by ethnicity, with studies estimating a range ...
... target genetic mutations known to play critical roles in the progression to metastatic disease. EGFR mutation is one of the most common targetable mutations in NSCLC particularly in non squamous histology. The incidence of EGFR mutations in NSCLC varies by ethnicity, with studies estimating a range ...
SQUAMOUS CELL CARCINOMA OF THE SKIN
... © 2013 College of American Pathologists (CAP). All rights reserved. The College does not permit reproduction of any substantial portion of these protocols without its written authorization. The College hereby authorizes use of these protocols by physicians and other health care providers in reportin ...
... © 2013 College of American Pathologists (CAP). All rights reserved. The College does not permit reproduction of any substantial portion of these protocols without its written authorization. The College hereby authorizes use of these protocols by physicians and other health care providers in reportin ...
Use of BAC aCGH for molecular karyotyping of whole
... hybridization (aCGH), however many of these samples are unsuitable for microarray analysis due to nucleic acid damage introduced during the fixation process. Several methods have been shown to be effective in the assessment of DNA quality from sources of damaged DNA, with PCR-based assays being the ...
... hybridization (aCGH), however many of these samples are unsuitable for microarray analysis due to nucleic acid damage introduced during the fixation process. Several methods have been shown to be effective in the assessment of DNA quality from sources of damaged DNA, with PCR-based assays being the ...
06_Aryo Tedjo_Revisi 020809_KLASIFIKASI BEBERAPA JENIS
... multiexcitation. Through this technique, the normal tissue and carcinoma are expected to be differentiated more significantly since the overall tissue specificity will be determined by the specific intensity that appears in the fluorescence emission spectrum of each natural fluorophore that is excit ...
... multiexcitation. Through this technique, the normal tissue and carcinoma are expected to be differentiated more significantly since the overall tissue specificity will be determined by the specific intensity that appears in the fluorescence emission spectrum of each natural fluorophore that is excit ...
Bladder Cancer
... bladder is transitional epithelium but it can change to squamous epithelium or columnar type under the effect of continuous irritation by inflammation, or stone formation) ...
... bladder is transitional epithelium but it can change to squamous epithelium or columnar type under the effect of continuous irritation by inflammation, or stone formation) ...
The breast cancer genome - a key for better oncology REVIEW Open Access
... Molecular classification has added important knowledge to breast cancer biology, but has yet to be implemented as a clinical standard. Full sequencing of breast cancer genomes could potentially refine classification and give a more complete picture of the mutational profile of cancer and thus aid th ...
... Molecular classification has added important knowledge to breast cancer biology, but has yet to be implemented as a clinical standard. Full sequencing of breast cancer genomes could potentially refine classification and give a more complete picture of the mutational profile of cancer and thus aid th ...
Squamous Cell Carcinoma
... conditions such as actinic keratosis, leukoplakia and Bowen’s disease can develop into Squamous Cell Skin Carcinoma. ...
... conditions such as actinic keratosis, leukoplakia and Bowen’s disease can develop into Squamous Cell Skin Carcinoma. ...
PHS 398 (Rev. 9/04), Biographical Sketch Format Page
... cancer biology and have published numerous research articles and reviews summarizing my contributions to the field of tumor progression and metastasis. I was the first to clone galectin-3 from tumor cells and established its signaling pathways during cancer progression and metastasis in experimental ...
... cancer biology and have published numerous research articles and reviews summarizing my contributions to the field of tumor progression and metastasis. I was the first to clone galectin-3 from tumor cells and established its signaling pathways during cancer progression and metastasis in experimental ...
Evaluation of Colonic Polyps 1
... MSI is a key factor in several cancers including colorectal, endometrial, ovarian and gastric cancers. Colorectal cancer studies have demonstrated two mechanisms for MSI occurrence. ► The first is in hereditary nonpolyposis colorectal cancer (HNPCC) or Lynch Syndrome, where an inherited mutation in ...
... MSI is a key factor in several cancers including colorectal, endometrial, ovarian and gastric cancers. Colorectal cancer studies have demonstrated two mechanisms for MSI occurrence. ► The first is in hereditary nonpolyposis colorectal cancer (HNPCC) or Lynch Syndrome, where an inherited mutation in ...
PPT
... e. Large lesions may undergo central necrosis, giving rise to cavitation. f. Are preceded by the development, over years, of squamous metaplasia or dysplasia in the bronchial ...
... e. Large lesions may undergo central necrosis, giving rise to cavitation. f. Are preceded by the development, over years, of squamous metaplasia or dysplasia in the bronchial ...
FCDS is pleased to announce the 7
... This is a reminder. The 2011 Consolidated Follow Back records are available for review. Consolidated Follow Back is a combination of AHCA, Ambulatory Surgery Center (AMBI) and the Death Clearance follow back process into a single follow back queue. FCDS completed the matching of the 2011 In-Patient ...
... This is a reminder. The 2011 Consolidated Follow Back records are available for review. Consolidated Follow Back is a combination of AHCA, Ambulatory Surgery Center (AMBI) and the Death Clearance follow back process into a single follow back queue. FCDS completed the matching of the 2011 In-Patient ...
Paradigms in Lung Cancer Molecular Pathology - 2015
... • Molecular abnormalities can be used to direct targeted therapy and improve patients’ outcomes • Mechanisms of resistance have been identified and new therapies have been developed • Liquid biopsy is an option for molecular testing • Immunotherapy is a new therapeutic option ...
... • Molecular abnormalities can be used to direct targeted therapy and improve patients’ outcomes • Mechanisms of resistance have been identified and new therapies have been developed • Liquid biopsy is an option for molecular testing • Immunotherapy is a new therapeutic option ...
Protocol for the Examination of Specimens From Patients With
... © 2013 College of Am erican Pathologists (CAP). All rights reserved. The College does not permit reproduction of any substantial portion of these protocols without its written authorization. The College hereby authorizes use of these protocols by physicians and other health care providers in reporti ...
... © 2013 College of Am erican Pathologists (CAP). All rights reserved. The College does not permit reproduction of any substantial portion of these protocols without its written authorization. The College hereby authorizes use of these protocols by physicians and other health care providers in reporti ...
SNVMix: predicting single nucleotide variants
... fraction fi = Naii , and then to call as SNVs those locations where fi is below some threshold. In the example in Figure 1A, applying threshold of 16 would successfully discard all columns (including the two columns which have singleton non-reference reads, which may be due to base-calling errors), ...
... fraction fi = Naii , and then to call as SNVs those locations where fi is below some threshold. In the example in Figure 1A, applying threshold of 16 would successfully discard all columns (including the two columns which have singleton non-reference reads, which may be due to base-calling errors), ...
isolated scapular metastasis in a patient with rectal carcinoma
... caused by secondary from adenocarcinoma of rectum. The diagnosis of metastatic adenocarcinoma was confirmed by fine needle aspiration cytology from the scapular mass (figure 4). CEA was 40 ng/ml. Palliative radiotherapy 3000CGry/10#/2 weeks was given to the patient. DISCUSSION: Colorectal cancer is ...
... caused by secondary from adenocarcinoma of rectum. The diagnosis of metastatic adenocarcinoma was confirmed by fine needle aspiration cytology from the scapular mass (figure 4). CEA was 40 ng/ml. Palliative radiotherapy 3000CGry/10#/2 weeks was given to the patient. DISCUSSION: Colorectal cancer is ...
National Prostate Cancer Audit
... • NPCA Minimum data set 3: The third category will be collected for all men for whom external beam radiation therapy or brachytherapy, is planned with or without hormone deprivation therapy ...
... • NPCA Minimum data set 3: The third category will be collected for all men for whom external beam radiation therapy or brachytherapy, is planned with or without hormone deprivation therapy ...