
Διαφάνεια 1 - rheumatology.gr
... Bacteria necessary but not sufficient Bacterial eradication does not necessarily lead to resolution Antibody response to bacteria predicts progressive disease and bone loss (e.g. IgG Anti- P. gingivalis) T-cell component (CD4:CD8 = 2:1, Tregs) B cell component (plasma cells, Ag presentatio ...
... Bacteria necessary but not sufficient Bacterial eradication does not necessarily lead to resolution Antibody response to bacteria predicts progressive disease and bone loss (e.g. IgG Anti- P. gingivalis) T-cell component (CD4:CD8 = 2:1, Tregs) B cell component (plasma cells, Ag presentatio ...
Autoimmunity - Egyptian Society of Pediatric Allergy and Immunology
... family bind to ligand-specific (high affinity) Trk receptors. In addition, all neurotrophins bind to the common pan-neurotrophin (low affinity) receptor p75NTR. The high affinity receptors mediate trophic effects, whereas the low affinity receptor may be involved in induction of apoptosis. 2-Neurotr ...
... family bind to ligand-specific (high affinity) Trk receptors. In addition, all neurotrophins bind to the common pan-neurotrophin (low affinity) receptor p75NTR. The high affinity receptors mediate trophic effects, whereas the low affinity receptor may be involved in induction of apoptosis. 2-Neurotr ...
Rheumatic Fever Etiology and Pathogenesis
... Mesenchymal cells cover the tonsillar region while Ectodermal cells cover the Skin. Hypothesis: GAS infection of Pharyngeal mesothelial cells sensitizes the cells in such a way which later manifests as endothelial cell damage of valves and mesothelial cell damage of joints. ...
... Mesenchymal cells cover the tonsillar region while Ectodermal cells cover the Skin. Hypothesis: GAS infection of Pharyngeal mesothelial cells sensitizes the cells in such a way which later manifests as endothelial cell damage of valves and mesothelial cell damage of joints. ...
11-28-04 Anti-inflammatory
... Pain quality is often described as a dull ache in • joint pain (osteoarthritis, gout) • muscle pain (myalgia) • headache (nonmigraine) ...
... Pain quality is often described as a dull ache in • joint pain (osteoarthritis, gout) • muscle pain (myalgia) • headache (nonmigraine) ...
Exercise for Joint Pain
... Joint pain, or arthralgia, associated with autoimmune disease often includes stiffness that lasts more than an hour along with redness, swelling and warmth near the joint itself. It commonly affects joints on both sides of the body especially smaller joints of the hands and feet. Some of the most co ...
... Joint pain, or arthralgia, associated with autoimmune disease often includes stiffness that lasts more than an hour along with redness, swelling and warmth near the joint itself. It commonly affects joints on both sides of the body especially smaller joints of the hands and feet. Some of the most co ...
Asymptomatic Apical Periodontitis
... If the periapical infection and inflammation extend through the marrow spaces of the jaw, the result is osteomyelitis. In this case, you can identify the offending tooth causing the diffuse and irregular bone destruction. ...
... If the periapical infection and inflammation extend through the marrow spaces of the jaw, the result is osteomyelitis. In this case, you can identify the offending tooth causing the diffuse and irregular bone destruction. ...
The Hygiene Hypothesis: Intestinal Parasites and
... “Conclusions: Ova therapy seems safe and effective in patients with active colitis.” ...
... “Conclusions: Ova therapy seems safe and effective in patients with active colitis.” ...
Brain-Spleen Inflammatory Coupling: A Literature Review 4 BRIEF MEDICAL REVIEWS
... 2005). For example, intravenous methyl prednisolone sodium succinate, a steroid that was once a mainstay therapy for TBI, was abandoned after being shown to worsen morbidity and mortality (Edwards et al., 2005). This suggests that the anti-inflammatory pathways affected by selective inhibition of br ...
... 2005). For example, intravenous methyl prednisolone sodium succinate, a steroid that was once a mainstay therapy for TBI, was abandoned after being shown to worsen morbidity and mortality (Edwards et al., 2005). This suggests that the anti-inflammatory pathways affected by selective inhibition of br ...
Gonorrhoea - Soa Aids Nederland
... In men: Men do usually have symptoms of gonorrhoea. The first signs appear between several days and several weeks after becoming infected. This could be a pus-like yellowish/ greenish discharge from the urethra (urine tube). There might be quite a lot of it. If the urethra is inflamed, there will al ...
... In men: Men do usually have symptoms of gonorrhoea. The first signs appear between several days and several weeks after becoming infected. This could be a pus-like yellowish/ greenish discharge from the urethra (urine tube). There might be quite a lot of it. If the urethra is inflamed, there will al ...
Six Hot Topics in Rheumatology
... immune responses, cancer cells and the effects of stress. Some people who have chronic stress from conditions such as depression/anxiety, chronic infections or severe chronic diseases will use all the cortisone their bodies produce during the night time, which results in deficient cortisone levels. ...
... immune responses, cancer cells and the effects of stress. Some people who have chronic stress from conditions such as depression/anxiety, chronic infections or severe chronic diseases will use all the cortisone their bodies produce during the night time, which results in deficient cortisone levels. ...
Inflammation

Inflammation (Latin, inflammatio) is part of the complex biological response of body tissues to harmful stimuli, such as pathogens, damaged cells, or irritants.Inflammation is a protective response that involves immune cells, blood vessels, and molecular mediators. The purpose of inflammation is to eliminate the initial cause of cell injury, clear out necrotic cells and tissues damaged from the original insult and the inflammatory process, and to initiate tissue repair.The classical signs of acute inflammation are pain, heat, redness, swelling, and loss of function. Inflammation is a generic response, and therefore it is considered as a mechanism of innate immunity, as compared to adaptive immunity, which is specific for each pathogen.Too little inflammation could lead to progressive tissue destruction by the harmful stimulus (e.g. bacteria) and compromise the survival of the organism. In contrast, chronic inflammation may lead to a host of diseases, such as hay fever, periodontitis, atherosclerosis, rheumatoid arthritis, and even cancer (e.g., gallbladder carcinoma). Inflammation is therefore normally closely regulated by the body.Inflammation can be classified as either acute or chronic. Acute inflammation is the initial response of the body to harmful stimuli and is achieved by the increased movement of plasma and leukocytes (especially granulocytes) from the blood into the injured tissues. A series of biochemical events propagates and matures the inflammatory response, involving the local vascular system, the immune system, and various cells within the injured tissue. Prolonged inflammation, known as chronic inflammation, leads to a progressive shift in the type of cells present at the site of inflammation and is characterized by simultaneous destruction and healing of the tissue from the inflammatory process.Inflammation is not a synonym for infection. Infection describes the interaction between the action of microbial invasion and the reaction of the body's inflammatory defensive response — the two components are considered together when discussing an infection, and the word is used to imply a microbial invasive cause for the observed inflammatory reaction. Inflammation on the other hand describes purely the body's immunovascular response, whatever the cause may be. But because of how often the two are correlated, words ending in the suffix -itis (which refers to inflammation) are sometimes informally described as referring to infection. For example, the word urethritis strictly means only ""urethral inflammation"", but clinical health care providers usually discuss urethritis as a urethral infection because urethral microbial invasion is the most common cause of urethritis.It is useful to differentiate inflammation and infection as there are many pathological situations where inflammation is not driven by microbial invasion - for example, atherosclerosis, type III hypersensitivity, trauma, ischaemia. There are also pathological situations where microbial invasion does not result in classic inflammatory response—for example, parasitosis, eosinophilia.