immunology – introduction - 1
... cellular elements. Caspases activated by • Intrinsic: mitochondrial membrane of inactive lymphocytes leak; products activate caspase = programmed cell death or death by neglect • Extrinsic: repeatedly activated T cells up-regulate FasL; reacts with Fas on same or adjacent cell • NK cell and cytotoxi ...
... cellular elements. Caspases activated by • Intrinsic: mitochondrial membrane of inactive lymphocytes leak; products activate caspase = programmed cell death or death by neglect • Extrinsic: repeatedly activated T cells up-regulate FasL; reacts with Fas on same or adjacent cell • NK cell and cytotoxi ...
4 Basic Principles of Immunology
... a) A family of more than twenty proteins in blood serum. b) Complement actions of other components of the immune system in the immune response. c) Activated by a complex series of reactions, working in four ways: (1) They can form a coating on the pathogen surface so that phagocytes (macrophages and ...
... a) A family of more than twenty proteins in blood serum. b) Complement actions of other components of the immune system in the immune response. c) Activated by a complex series of reactions, working in four ways: (1) They can form a coating on the pathogen surface so that phagocytes (macrophages and ...
Blood Product Modifications - UCLA Department of Pathology
... Benefits of leukoreduction o Prevention of alloimmunization to donor HLA antigens Anti-HLA can mediate graft rejection and immune mediated destruction of platelets o Leukoreduced products are indicated for transplant recipients or patients who are likely platelet transfusion dependent o Prevention ...
... Benefits of leukoreduction o Prevention of alloimmunization to donor HLA antigens Anti-HLA can mediate graft rejection and immune mediated destruction of platelets o Leukoreduced products are indicated for transplant recipients or patients who are likely platelet transfusion dependent o Prevention ...
Slide 1
... Type III – Caused by immunocomplexes Type IV – Delayed type (DTH) and contact hypersensitivity (TH1 reaction) ...
... Type III – Caused by immunocomplexes Type IV – Delayed type (DTH) and contact hypersensitivity (TH1 reaction) ...
The Gene Ontology and Immune System Processes
... • Developed for the annotation of gene products, primarily proteins, but also RNAs of various types, to provide a common language for representing protein properties. • Predates BFO and the OBO Foundry, and is still being improved to match recent best practices in ontology building. ...
... • Developed for the annotation of gene products, primarily proteins, but also RNAs of various types, to provide a common language for representing protein properties. • Predates BFO and the OBO Foundry, and is still being improved to match recent best practices in ontology building. ...
PPS - Doctor of the Future
... shallow answers that leave them puzzled with the mystery of “Why is this happening to me?” and “ What can I do about it?” • Trends research over 10 years ago identified a number of factors essential to being successful in the nutritional field – one of those was establishing yourself as an expert ...
... shallow answers that leave them puzzled with the mystery of “Why is this happening to me?” and “ What can I do about it?” • Trends research over 10 years ago identified a number of factors essential to being successful in the nutritional field – one of those was establishing yourself as an expert ...
Your lab partner cultured a population of mature B cells in the
... cells; on the surface of phagocytes, CR1 recognizes C3b, the main component of complement, and promotes phagocytosis (this is done in conjunction with the C5a receptor, otherwise phagocytosis would not occur). CR1 is also involved in complement regulation, promoting the dissociation of the C3 conver ...
... cells; on the surface of phagocytes, CR1 recognizes C3b, the main component of complement, and promotes phagocytosis (this is done in conjunction with the C5a receptor, otherwise phagocytosis would not occur). CR1 is also involved in complement regulation, promoting the dissociation of the C3 conver ...
Document
... This allows the next response to be a true secondary response – ie faster and bigger and with higher affinity IgG To avoid immune interference If another live vaccine is given while the immune system is making a primary immune response, the activation of the innate immune system may neutralise the s ...
... This allows the next response to be a true secondary response – ie faster and bigger and with higher affinity IgG To avoid immune interference If another live vaccine is given while the immune system is making a primary immune response, the activation of the innate immune system may neutralise the s ...
AIDS and its Effect on the Immune Response
... results in the destruction of an individual’s immune system. The virus that causes AIDS is passed from an infected individual to another person by means of body fluids such as blood, semen, or vaginal secretions. The virus itself, however, does not cause that life-threatening symptoms associated wit ...
... results in the destruction of an individual’s immune system. The virus that causes AIDS is passed from an infected individual to another person by means of body fluids such as blood, semen, or vaginal secretions. The virus itself, however, does not cause that life-threatening symptoms associated wit ...
ARTIFICIAL IMMUNE SYSTEMS FOR ILLNESSES DIAGNOSTIC Ubiquitous Computing and Communication Journal
... reduction and minimizes the processing time. The AIRS2 training steps are the same as AIRS one, just some changes which are presented as following: 1- It’s not necessary to initialize the ARB set. 2- It’s not necessary to mutate the ARBs class feature, because in AIRS2 we are interesting only about ...
... reduction and minimizes the processing time. The AIRS2 training steps are the same as AIRS one, just some changes which are presented as following: 1- It’s not necessary to initialize the ARB set. 2- It’s not necessary to mutate the ARBs class feature, because in AIRS2 we are interesting only about ...
No Slide Title - University of Nottingham
... Variable regions is likely to be only one factor controlling the immunogenicity of therapeutic antibodies. However it is the final sequence of the antibodies which matters and not the route by which they were made. For example it is possible to come up with alternative humanised sequences for the sa ...
... Variable regions is likely to be only one factor controlling the immunogenicity of therapeutic antibodies. However it is the final sequence of the antibodies which matters and not the route by which they were made. For example it is possible to come up with alternative humanised sequences for the sa ...
Introduction
... Primary Phenomenon – Sensitization Secondary Phenomenon – Lattice formation Tertiary Phenomenon – Detected by affect on tissues or cells. ...
... Primary Phenomenon – Sensitization Secondary Phenomenon – Lattice formation Tertiary Phenomenon – Detected by affect on tissues or cells. ...
Chapter 8
... They are called lymphoid organs because they are home to lymphocytes--the white blood cells that are key operatives of the immune system. Within these organs, the lymphocytes grow, develop, and are deployed. Bone marrow, the soft tissue in the hollow center of bones, is the ultimate source of all bl ...
... They are called lymphoid organs because they are home to lymphocytes--the white blood cells that are key operatives of the immune system. Within these organs, the lymphocytes grow, develop, and are deployed. Bone marrow, the soft tissue in the hollow center of bones, is the ultimate source of all bl ...
Instructor`s Guide
... passive, artificial immunity: A way to acquire immunity to a particular disease by receiving serum from the blood of someone who has had that disease, and who has already developed antibodies to fight it. It differs from active artificial immunity in that it usually only lasts for a few months. A te ...
... passive, artificial immunity: A way to acquire immunity to a particular disease by receiving serum from the blood of someone who has had that disease, and who has already developed antibodies to fight it. It differs from active artificial immunity in that it usually only lasts for a few months. A te ...
MCB 150: Molecular Immunology - Department of Molecular & Cell
... Lymphocytes of the adaptive immune system T helper cells: regulate other immune cells T cytotoxic (killer) cells: kill infected cells B cells: produce antibodies (immunoglobulin) Dendritic cells and macrophage: directly kill microbes by phagocytosis and other mechanisms. They also help to activate T ...
... Lymphocytes of the adaptive immune system T helper cells: regulate other immune cells T cytotoxic (killer) cells: kill infected cells B cells: produce antibodies (immunoglobulin) Dendritic cells and macrophage: directly kill microbes by phagocytosis and other mechanisms. They also help to activate T ...
Software Modeling of the Complement System and its role in
... Innate immunity however does not specifically recognize every possible antigen. It recognizes a few highly conserved structures called pathogen associated molecular patterns present in many different microorganisms. The immune cells have pattern recognition receptors complementary for these common p ...
... Innate immunity however does not specifically recognize every possible antigen. It recognizes a few highly conserved structures called pathogen associated molecular patterns present in many different microorganisms. The immune cells have pattern recognition receptors complementary for these common p ...
Ouchterlony Procedure
... crosses the placenta conferring passive immunity to a fetus. IgD - A monomer - Found on the surface of B cells probably allowing recognition of antigens thus triggering differentiation into plasma and memory B cells ...
... crosses the placenta conferring passive immunity to a fetus. IgD - A monomer - Found on the surface of B cells probably allowing recognition of antigens thus triggering differentiation into plasma and memory B cells ...
Complement system
The complement system is a part of the immune system that helps or complements the ability of antibodies and phagocytic cells to clear pathogens from an organism. It is part of the innate immune system, which is not adaptable and does not change over the course of an individual's lifetime. However, it can be recruited and brought into action by the adaptive immune system.The complement system consists of a number of small proteins found in the blood, in general synthesized by the liver, and normally circulating as inactive precursors (pro-proteins). When stimulated by one of several triggers, proteases in the system cleave specific proteins to release cytokines and initiate an amplifying cascade of further cleavages. The end-result of this activation cascade is massive amplification of the response and activation of the cell-killing membrane attack complex. Over 30 proteins and protein fragments make up the complement system, including serum proteins, serosal proteins, and cell membrane receptors. They account for about 5% of the globulin fraction of blood serum and can serve as opsonins.Three biochemical pathways activate the complement system: the classical complement pathway, the alternative complement pathway, and the lectin pathway.