DEVELOPMENT AND CHARACTERIZATION OF A TRANSGENIC
... connect the strands of the beta barrels and in the extensions at their amino and carboxyl termini. One copy of each capsid protein forms a protomer. Five protomers assemble into a pentamer and 12 pentamers assemble into the viral capsid. Figure 2 shows the architecture of a pentamer. VP1 encircles ...
... connect the strands of the beta barrels and in the extensions at their amino and carboxyl termini. One copy of each capsid protein forms a protomer. Five protomers assemble into a pentamer and 12 pentamers assemble into the viral capsid. Figure 2 shows the architecture of a pentamer. VP1 encircles ...
Introduction to Modern Virology
... bear in order to elucidate their subject and thus pick up some of the excitement of working in this field. Virology is a vibrant area and its study, far from being constraining, opens up a vista in which virus infections can be understood in the context of the biology of their hosts. ...
... bear in order to elucidate their subject and thus pick up some of the excitement of working in this field. Virology is a vibrant area and its study, far from being constraining, opens up a vista in which virus infections can be understood in the context of the biology of their hosts. ...
The characterization of inner core protein VP6 of African Horsesickness Virus
... CHAPTER 1: LITERATURE REVIEW 1.1 INTRODUCTION In 1898 researchers identified infectious agents that were smaller than the smallest known bacteria. Viruses are obligate intracellular parasites that use the machinery of the host cell to replicate. They consist of a DNA or RNA genome surrounded by a pr ...
... CHAPTER 1: LITERATURE REVIEW 1.1 INTRODUCTION In 1898 researchers identified infectious agents that were smaller than the smallest known bacteria. Viruses are obligate intracellular parasites that use the machinery of the host cell to replicate. They consist of a DNA or RNA genome surrounded by a pr ...
chapter 1 - UTMB Health SHARED Home
... cholesterol-dependency of CHIKV for growth and entry into C6/36 cells, and is responsible for increase in the pH dependency of CHIKV fusion reaction. However, analysis of viruses with specific mutations at position E1-226, and at other CHIKV genomic regions that modulate cholesterol dependency of CH ...
... cholesterol-dependency of CHIKV for growth and entry into C6/36 cells, and is responsible for increase in the pH dependency of CHIKV fusion reaction. However, analysis of viruses with specific mutations at position E1-226, and at other CHIKV genomic regions that modulate cholesterol dependency of CH ...
Characterization of bovine viral diarrhea viruses by their interactions
... Ether and chloroform sensitivities of BYD viruses have also been reported by other workers (17» 18, 22). A single contrary finding that the Oregon C24V strain of BVD viruses Is ether-stable was reported by Taylor et §d. (19). On the basis of size, lack of hemadsorption, and ether stability, these au ...
... Ether and chloroform sensitivities of BYD viruses have also been reported by other workers (17» 18, 22). A single contrary finding that the Oregon C24V strain of BVD viruses Is ether-stable was reported by Taylor et §d. (19). On the basis of size, lack of hemadsorption, and ether stability, these au ...
genetics and functions of herpes simplex virus type 1 membrane
... Table 4.1: Amino acid sequences of mutations .........................................................177 Table 4.2: Complementation results for cell fusion ...................................................184 Table 4.3: Differential effects of mutations on infectious virion production and cell fu ...
... Table 4.1: Amino acid sequences of mutations .........................................................177 Table 4.2: Complementation results for cell fusion ...................................................184 Table 4.3: Differential effects of mutations on infectious virion production and cell fu ...
ABSTRACT Title of Document:
... 3.4.1 Further adaptation of qa-mall/178 (H2N2) in chickens leads to a virus with expanded tissue tropism.......................................................................................55 3.4.2 Sequence analysis of ch-qa/178..................................................................56 3 ...
... 3.4.1 Further adaptation of qa-mall/178 (H2N2) in chickens leads to a virus with expanded tissue tropism.......................................................................................55 3.4.2 Sequence analysis of ch-qa/178..................................................................56 3 ...
Dissertation zur Erlangung des Doktorgrades der Fakultät für Chemie und Pharmazie
... sequence homology, have been identified. Although the other serotypes have attracted increasing attention during recent years, AAV type 2 is the most prominent serotype for gene therapy, being the first isolated, cloned, and best characterized. Since all following descriptions will refer to AAV type ...
... sequence homology, have been identified. Although the other serotypes have attracted increasing attention during recent years, AAV type 2 is the most prominent serotype for gene therapy, being the first isolated, cloned, and best characterized. Since all following descriptions will refer to AAV type ...
Genetics of Herpes Simplex Virus Type
... diagnostic PCR to confirm the presence of each mutation. (C) PCR fragments containing the kanamycin resistance or GFP-Zeocin resistance gene cassette flanked by approximately 50 bp of viral sequences on both sides were used for targeted GET recombination in E. coli to construct pYEbac102 mutant BACs ...
... diagnostic PCR to confirm the presence of each mutation. (C) PCR fragments containing the kanamycin resistance or GFP-Zeocin resistance gene cassette flanked by approximately 50 bp of viral sequences on both sides were used for targeted GET recombination in E. coli to construct pYEbac102 mutant BACs ...
Chapter 20
... • In 1935, biologist Wendell Stanley of the Rockefeller Institute purified tobacco mosaic virus (TMV) and determined that the purified virus is a crystal. • Stanley concluded that TMV is a chemical rather than an organism. Chapter menu ...
... • In 1935, biologist Wendell Stanley of the Rockefeller Institute purified tobacco mosaic virus (TMV) and determined that the purified virus is a crystal. • Stanley concluded that TMV is a chemical rather than an organism. Chapter menu ...
HB_20_win
... glycoproteins change to the point that they now recognize a new cell surface receptor. This receptor is found on the subset of lymphocytes called T cells. • Unlike its activity in macrophages, HIV reproduces in T cells and then destroys them. • It is this destruction of the body’s T cells that block ...
... glycoproteins change to the point that they now recognize a new cell surface receptor. This receptor is found on the subset of lymphocytes called T cells. • Unlike its activity in macrophages, HIV reproduces in T cells and then destroys them. • It is this destruction of the body’s T cells that block ...
Viruses - Red Wing Public Schools
... • After the viral genes have entered the cell, they use the host cell to replicate viral genes and to make viral proteins, such as capsids. • The proteins are then assembled with the replicated viral genes to form complete viruses. The host cell is broken open and releases newly made viruses. Chapte ...
... • After the viral genes have entered the cell, they use the host cell to replicate viral genes and to make viral proteins, such as capsids. • The proteins are then assembled with the replicated viral genes to form complete viruses. The host cell is broken open and releases newly made viruses. Chapte ...
Virus Inactivation - Evaluation of Processes used in Biowaste
... thermal and biological treatments such as composting, and disinfection using chemicals such as ammonia. As the high eggshell content of HW could make it unsuitable for composting and anaerobic digestion, liming is often used in Sweden as a chemical method for sanitation. However, this treatment resu ...
... thermal and biological treatments such as composting, and disinfection using chemicals such as ammonia. As the high eggshell content of HW could make it unsuitable for composting and anaerobic digestion, liming is often used in Sweden as a chemical method for sanitation. However, this treatment resu ...
Amino Acid Changes in the HIV-1 gp41 Membrane Proximal Region
... et al., 2016). Examination of the C-terminal MPER sequences revealed three amino acid changes (K677 N, W680R, and K683Q) in HIV-1 Envs isolated at 12 months and beyond (Fig. 1A). The month 21 and month 30 viruses with the W680R mutation were resistant to neutralization by the MPER bnAb 4E10 (Fig. 1A ...
... et al., 2016). Examination of the C-terminal MPER sequences revealed three amino acid changes (K677 N, W680R, and K683Q) in HIV-1 Envs isolated at 12 months and beyond (Fig. 1A). The month 21 and month 30 viruses with the W680R mutation were resistant to neutralization by the MPER bnAb 4E10 (Fig. 1A ...
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... accompanied by continuous extensive viral genetic diversification. Little is known about how virus diversification is influencing the viral replication capacity (RC) over time. The aim of this study was ...
... accompanied by continuous extensive viral genetic diversification. Little is known about how virus diversification is influencing the viral replication capacity (RC) over time. The aim of this study was ...
counting viruses in mat - Research Explorer
... The top layer of these mats is mostly composed of photoautotrophs (filamentous cyanobacteria and eukaryotic phytobenthos) that produce organic carbon, which is decomposed in a succession of layers of different heterotrophic prokaryotes reflecting concentration gradients in oxygen and other electron ...
... The top layer of these mats is mostly composed of photoautotrophs (filamentous cyanobacteria and eukaryotic phytobenthos) that produce organic carbon, which is decomposed in a succession of layers of different heterotrophic prokaryotes reflecting concentration gradients in oxygen and other electron ...
Henry Potosnak
... After connecting with the matching receptor, the bacteriophages begin their assault on the bacteria. More complex bacteriophages use a motion that can be compared to that of a syringe to inject their genetic material into the bacteria cell. Other bacteriophages use their tail fibers to move closer t ...
... After connecting with the matching receptor, the bacteriophages begin their assault on the bacteria. More complex bacteriophages use a motion that can be compared to that of a syringe to inject their genetic material into the bacteria cell. Other bacteriophages use their tail fibers to move closer t ...
The viral killer system in yeast: from molecular biology to application
... Since the initial discovery of the yeast killer system almost 40 years ago, intensive studies have substantially strengthened our knowledge in many areas of biology and provided deeper insights into basic aspects of eukaryotic cell biology as well as into virus^host cell interactions and general yea ...
... Since the initial discovery of the yeast killer system almost 40 years ago, intensive studies have substantially strengthened our knowledge in many areas of biology and provided deeper insights into basic aspects of eukaryotic cell biology as well as into virus^host cell interactions and general yea ...
Understanding phage, the viruses that infect
... d'Hérelle, working at the Pasteur Institute in Paris, announced on September 3, 1917 that he discovered "an invisible, antagonistic microbe of the dysentery bacillus". For d’Herelle, there was no question as to the nature of his discovery: "In a flash I had understood: what caused my clear spots was ...
... d'Hérelle, working at the Pasteur Institute in Paris, announced on September 3, 1917 that he discovered "an invisible, antagonistic microbe of the dysentery bacillus". For d’Herelle, there was no question as to the nature of his discovery: "In a flash I had understood: what caused my clear spots was ...
MOLECULAR CHARACTERIZATION OF A PORCINE PICOBIRNAVIRUS RNA- DEPENDENT RNA POLYMERASE. by
... in humans and animals. Picobirnavirus dsRNA has been detected in many cases when diagnostic PAGE screening for rotavirus dsRNA is performed. During this routine diagnosis, picobirnavirus dsRNA has been detected in the faeces of patients with and without viral gastroenteritis. Despite the common occu ...
... in humans and animals. Picobirnavirus dsRNA has been detected in many cases when diagnostic PAGE screening for rotavirus dsRNA is performed. During this routine diagnosis, picobirnavirus dsRNA has been detected in the faeces of patients with and without viral gastroenteritis. Despite the common occu ...
Chapter 23 Viruses and Prokaryotes
... • Takes over cell’s translation and transcription to reproduce Copyright © 2005 Brooks/Cole — Thomson Learning ...
... • Takes over cell’s translation and transcription to reproduce Copyright © 2005 Brooks/Cole — Thomson Learning ...
Assembly and budding of rabies virus
... superantigen‐like properties (Lafon et al., 1992). Already in 1885, Louis Pasteur treated a boy with desiccated spinal cords derived from rabies‐infected rabbits after the boy had been bitten by a rabid dog. This was the first successful use of a post‐exposure pro ...
... superantigen‐like properties (Lafon et al., 1992). Already in 1885, Louis Pasteur treated a boy with desiccated spinal cords derived from rabies‐infected rabbits after the boy had been bitten by a rabid dog. This was the first successful use of a post‐exposure pro ...
Human herpes virus: Bacteria and periodontium
... the leading cause of human viral diseases. Greek word Herpein from which Herpes name come, which means to creep. Nature ...
... the leading cause of human viral diseases. Greek word Herpein from which Herpes name come, which means to creep. Nature ...
Human herpes virus: Bacteria and periodontium
... from which Herpes name come, which means to creep. Nature Journal of Oral Disease Markers ● Vol. 1:1 ● 2015 ...
... from which Herpes name come, which means to creep. Nature Journal of Oral Disease Markers ● Vol. 1:1 ● 2015 ...
Geometry
... blocks, different types of building blocks, in the easiest case, a sino-one and then repeatedly synthesize it and use it, and that is what the virus does, and the multiplicity with which those building blocks then come together to form these containers are determined by the symmetry, in this case th ...
... blocks, different types of building blocks, in the easiest case, a sino-one and then repeatedly synthesize it and use it, and that is what the virus does, and the multiplicity with which those building blocks then come together to form these containers are determined by the symmetry, in this case th ...