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Intake of fat-soluble vitamins - Ghent University Library
Intake of fat-soluble vitamins - Ghent University Library

... intake of fat-soluble vitamins. Toddlers have the highest exposure per kg of body weight and they are considered to be one of the groups at risk. Despite this, the problem of inadequacy is still not solved (e.g. vitamin D). Subsequently an assessment of the current situation was needed, in order to ...
Vitamin K, moreover, is involved in much more than osteocalcin
Vitamin K, moreover, is involved in much more than osteocalcin

... even between strains of laboratory rats,15,16 and has not been determined in humans. The mammary glands appear to be especially efficient at making this conversion, presumably because vitamin K2 is essential for the growing infant.17 Vitamin K2 is also produced by lactic acid bacteria,18 although ba ...
6 Thiamin (Vitamin B1)
6 Thiamin (Vitamin B1)

... 10% because information is not available on the standard deviation of the requirement for thiamin. RDA is thus defined as equal to the estimated average requirement (EAR) plus twice the CV to cover the needs of 97 to 98 of the individuals in the group, or 120% of the EAR. In considering the requirem ...
Safety of Vitamin and Mineral Supplements
Safety of Vitamin and Mineral Supplements

... nutrients are helpful components of the total diet, with the supplemental intakes providing several established benefits for many persons, especially those in specific age and gender groups. Because of the tendency toward increased consumption by persons seeking to achieve the health benefits, as pa ...
By observing chickens, Christiaan Eijkman helped discover a cure
By observing chickens, Christiaan Eijkman helped discover a cure

... iron’s role in the citric acid cycle and the role of both iron and copper in the electron transport chain. See Chapter 15 for more detail on magnesium’s role in glycolysis, gluconeogenesis, and the citric acid cycle. This chapter also briefly describes choline, a newcomer to the list of important nu ...
1 Professor D.Sci. Judit Kosáry Nutritional biochemistry of the
1 Professor D.Sci. Judit Kosáry Nutritional biochemistry of the

... metabolic integrity and the prevention of deficiency. There are suggestions about the benefit of vitamins (and other nutritional supplements) intake higher than nutritional requirements. In some cases no scientific foundations exist and these hypotheses are based only on their pharmacological action ...
Invest in your bones Bone Appétit
Invest in your bones Bone Appétit

... for maintaining calcium levels in the blood. Blood calcium levels have to be tightly maintained at a constant level, for calcium’s other roles such as in nerve and muscle functioning. Recommended daily calcium intakes for populations vary between countries, often as a result of differing use and int ...
Printer Friendly PDF
Printer Friendly PDF

... vitamins A, C, D, E, B1, B12 and folic acid, as well as zinc and selenium. All combined, these deficiencies clearly indicate severe malnutrition. B12 injections corrected his anemia, but not his visual loss. Do you see the disconnection between the case history and the headlines? Starches, vegetabl ...
to - HealthFitLabs
to - HealthFitLabs

... vitamin known to man. It is consumed in a supplemental form by millions of people across the world for its antioxidant properties, which are well-documented in medical research. Calcium Ascorbate is an optimal nutritional supplement that combines Ascorbic Acid (Vitamin C) with Calcium Carbonate. By ...
Evaluation of total phenolic content, total antioxidant activity, and
Evaluation of total phenolic content, total antioxidant activity, and

... was washed, peeled, and stored. The fruit arils were crushed and squeezed by squeezing machine(National Juicer/Blender). The pomegranate juice (PJ) was filtered to remove any water-insoluble materials. Liquid nitrogen and freeze-drying machine was used to make powder from pomegranate juice, and then ...
Dr. Rath Cellular Nutrient Programme
Dr. Rath Cellular Nutrient Programme

... all the nutrient factors it needs for healthy metabolic processes. A food supplement can contribute to this supply. Our Cellular Nutrient Programme is divided into three groups, to allow for differing or increased nutrient requirements: a range of Basic Formulas, a Reconstructive Programme, and a va ...
Nutrition: vitamins and minerals
Nutrition: vitamins and minerals

... the last 20 years due to supplements to their feed. Pregnant women are advised to restrict their intake of liver and pâté made from liver, since there is some evidence that high doses of vitamin A can cause birth defects. However, vitamin A is an essential part of the human diet and severe health pr ...
Omega-3 expert - Orkla Health UK
Omega-3 expert - Orkla Health UK

... the few Omega-3 producers in the world having full control of the value chain for cod liver oil. This gives us greater control of the purity and quality of the oil. When releasing a batch, we can trace the raw material back to the place and time of the ...
Vitamins in Animal Nutrition
Vitamins in Animal Nutrition

... the deficiency: Common: retarded growth and fertility disorders. Poultry: poor plumage, inflammatory lesions of beak, legs and toes, fatty liver and kidney syndrome (FLKS). Pigs: hair loss, inflammation of the hooves and hoof-sole lesions. Cattle, sheep and horses: brittle horns and grooves and crac ...
counterskills - Alliance Healthcare
counterskills - Alliance Healthcare

... varied and balanced diet. However, some customers may choose to take vitamin and mineral supplements, either because they have been recommended to do so by a healthcare professional because they feel run down or know they are not eating as well as they should. Care should always be taken when recomm ...
Determination of vitamin D in foods: Current
Determination of vitamin D in foods: Current

... winter, however, oral intake of vitamin D may be the primary source as the UVB-related synthesis in the skin is limited. Similarly, oral intake of vitamin D is the primary source all the year round for people not exposed to sunlight, for example, due to wearing of clothing that prevents skin exposur ...
CoA - PetfoodIndustry
CoA - PetfoodIndustry

... Approved: AAFCO and FDA approved ...
20 key nutrients for bone health — an overview
20 key nutrients for bone health — an overview

... complex interplay of hormones and other factors, chief of which is vitamin D.2425  ...
Neuroenhancement with Vitamin B12—Underestimated
Neuroenhancement with Vitamin B12—Underestimated

... cerebral atrophy, and Vitamin B12 status show clinically relevant interrelationships. The clinical manifestations of B12 deficiency in infants and small children whose mothers suffered from Vitamin B12 deficiency require special attention. Such infants may develop severe haematological and neurologi ...
Neuroenhancement with Vitamin B12—Underestimated
Neuroenhancement with Vitamin B12—Underestimated

... cerebral atrophy, and Vitamin B12 status show clinically relevant interrelationships. The clinical manifestations of B12 deficiency in infants and small children whose mothers suffered from Vitamin B12 deficiency require special attention. Such infants may develop severe haematological and neurologi ...
Vitamin B12 QuickFacts Datos en español Health Professional Other
Vitamin B12 QuickFacts Datos en español Health Professional Other

... Evidence from the Framingham Offspring Study suggests that the prevalence of vitamin B12 deficiency in young adults might be greater than previously assumed [15]. This study found that the percentage of participants in three age groups (26– 49 years, 50–64 years, and 65 years and older) with defici ...
NSC 207 - National Open University of Nigeria
NSC 207 - National Open University of Nigeria

... AcetylcoA + CO 2 + NADH The reaction is catalyzed by the Pyruvate dehydrogenase complex ...
The medical importance of vitamin A and carotenoids
The medical importance of vitamin A and carotenoids

... Some 75 years ago, vitamin A was discovered as a fat-soluble growth factor present in liver, and recognized as an essential biochemical for normal vision in man and animals. It is, in fact, the first vitamin to be discovered. Today, after several decades, very little is known about the vitamin’s bio ...
Evaluating the public health significance of micronutrient malnutrition
Evaluating the public health significance of micronutrient malnutrition

... 1.2). Iron deficiency has been shown to reduce physical endurance, even in the absence of anaemia (80), and severe anaemia has been associated with an increased risk of both maternal and child mortality (81,82). As indicated previously (see section 1.1), there is now substantial evidence to suggest ...
Avitron® V
Avitron® V

... transketolase in the direct oxidation pathway of glucose metabolism. In thiamine deficiency, pyruvic acid and lactic acid accumulate in tissues. Thiamine deficiency affects the peripheral nervous system, the gastrointestinal tract, and the cardiovascular system. Thiamine is not stored in the body, i ...
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Vitamin D



Vitamin D refers to a group of fat-soluble secosteroids responsible for enhancing intestinal absorption of calcium, iron, magnesium, phosphate and zinc. In humans, the most important compounds in this group are vitamin D3 (also known as cholecalciferol) and vitamin D2 (ergocalciferol). Cholecalciferol and ergocalciferol can be ingested from the diet and from supplements. Very few foods contain vitamin D; synthesis of vitamin D (specifically cholecalciferol) in the skin is the major natural source of the vitamin. Dermal synthesis of vitamin D from cholesterol is dependent on sun exposure (specifically UVB radiation).Vitamin D from the diet or dermal synthesis from sunlight is biologically inactive; activation requires enzymatic conversion (hydroxylation) in the liver and kidney. Evidence indicates the synthesis of vitamin D from sun exposure is regulated by a negative feedback loop that prevents toxicity, but because of uncertainty about the cancer risk from sunlight, no recommendations are issued by the Institute of Medicine (US), for the amount of sun exposure required to meet vitamin D requirements. Accordingly, the Dietary Reference Intake for vitamin D assumes no synthesis occurs and all of a person's vitamin D is from food intake, although that will rarely occur in practice. As vitamin D is synthesized in adequate amounts by most mammals exposed to sunlight, it is not strictly a vitamin, and may be considered a hormone as its synthesis and activity occur in different locations. Vitamin D has a significant role in calcium homeostasis and metabolism. Its discovery was due to effort to find the dietary substance lacking in rickets (the childhood form of osteomalacia).Beyond its use to prevent osteomalacia or rickets, the evidence for other health effects of vitamin D supplementation in the general population is inconsistent. The best evidence of benefit is for bone health. The effect of vitamin D supplementation on mortality is not clear, with one meta-analysis finding a decrease in mortality in elderly people, and another concluding no clear justification exists for recommending vitamin D. Because it found mounting evidence for a benefit to bone health, though it had not found good evidence of other benefits, the Food and Drug Administration of the United States has proposed requiring manufacturers to declare the amount of Vitamin D on nutrition facts labels, as ""nutrients of public health significance"". As of August 2015, this is currently still open for public comment.In the liver, cholecalciferol (vitamin D3) is converted to calcidiol, which is also known as calcifediol (INN), 25-hydroxycholecalciferol (aka 25-hydroxyvitamin D3 — abbreviated 25(OH)D3). Ergocalciferol (vitamin D2) is converted in the liver to 25-hydroxyergocalciferol (aka 25-hydroxyvitamin D2 — abbreviated 25(OH)D2). These two specific vitamin D metabolites are measured in serum to determine a person's vitamin D status. Part of the calcidiol is converted by the kidneys to calcitriol, the biologically active form of vitamin D. Calcitriol circulates as a hormone in the blood, regulating the concentration of calcium and phosphate in the bloodstream and promoting the healthy growth and remodeling of bone. Calcitriol also affects neuromuscular and immune function.
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