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Future directions in the prevention of prostate cancer
Future directions in the prevention of prostate cancer

... a host of adverse effects and most men with metastatic prostate cancer will ultimately die of their disease. In response to this challenge, serum prostate-specific antigen (PSA) testing became highly prevalent in the late 1980s. Current US guidelines regarding PSA screening vary, but the 2013 Americ ...
Causes of death in men with localized prostate cancer: a nationwide
Causes of death in men with localized prostate cancer: a nationwide

... partnership status and was defined as not single, single with children, or single with no children. From the NPCR, which started in 1996 and captures 98% of all newly diagnosed, biopsy-confirmed PCa cases as compared with the Swedish Cancer Registry [8], we had detailed information about tumour charac ...
International & National Patterns of Cancer Rates
International & National Patterns of Cancer Rates

Announcements - Yale Cancer Center
Announcements - Yale Cancer Center

... extended for an additional 5 years following an extensive grant submission and review process. The award includes $12.2 million in funding over 5 years to support the Center's 7 research programs and 8 shared resources, along with the continuation of the Center's comprehensive status, the most prest ...
Breast Cancer - Georgetown University
Breast Cancer - Georgetown University

... outcomes because of limited number or power of studies, important flaws in their design or conduct, gaps in the chain of evidence, or lack of information on important health ...
METABOLIC SYNDROME AND OXIDATIVE STRESS IN GHANAIANS PRESENTING WITH PROSTATE CANCER
METABOLIC SYNDROME AND OXIDATIVE STRESS IN GHANAIANS PRESENTING WITH PROSTATE CANCER



The Cancer Vanguard
The Cancer Vanguard

Cancer Screening in ESRD - American Society of Nephrology
Cancer Screening in ESRD - American Society of Nephrology

... data, the SIR for cervical cancer in ESRD patients suggests that young women (and men) with ESRD American Society of Nephrology ...
Genetic Testing-BRCA
Genetic Testing-BRCA

... MUST MEET ALL OF THE FOLLOWING: 1. The results of the genetic testing will directly impact surveillance or treatment of the member. 2. One of the following criteria is met: a. Three or more close relatives1 (including the member) on the same side of the family have breast (either invasive or non-inv ...
What is Cancer? - Rainbow Health Ontario
What is Cancer? - Rainbow Health Ontario

... age 50, and risks increase after age 70. In North America, for reasons that are not understood, black men are at highest risk, with white men having medium risk and Asian men having low rates. MTFs who are not taking hormones are at the same risk for prostate cancer as non-trans men. Feminizing horm ...
The changing therapeutic landscape of castration
The changing therapeutic landscape of castration

... The changing therapeutic landscape of castration-resistant prostate cancer Timothy A. Yap, Andrea Zivi, Aurelius Omlin and Johann S. de Bono Abstract | Castration-resistant prostate cancer (CRPC) has a poor prognosis and remains a significant therapeutic challenge. Before 2010, only docetaxel-based ...
MicroRNAs and zinc metabolism-related gene
MicroRNAs and zinc metabolism-related gene

... is diagnosed soon. Thus, the search for suitable biomarkers used for early detection of the presence and progression of the disease, as well as the prediction after the clinical interventions is ongoing. The current prostate cancer biomarkers do not fulfill all a forementioned requirement as there r ...
ucsf urology - UCSF Department of Urology
ucsf urology - UCSF Department of Urology

... studies. The skill and experience of the provider and hospital, as well as the technology used, play an important role in patient outcomes. A large body of literature has shown that positive outcomes are correlated with the volume of procedures performed by a surgeon and facility. It is important to ...
ln compliance with the Canadian Privacy
ln compliance with the Canadian Privacy

... grading system provide signifieant prognostic information but it has also exhibited highly reproducible results (2). The Gleason grading system is based on the gIanduIar pattern of the tumor as identified by microscopic examination of prostatic tissue un der low magnification (2,23). A 5-step gradin ...
Cancer Screening: A Review of Current Evidence and
Cancer Screening: A Review of Current Evidence and

... Early History of Cancer Screening • 1920 – Dr. George Papanicolaou begins studying the Papanicolaou test as a method of understanding the cervical changes associated with the menstrual cycle. • 1923 – Panpanicolaou reports his findings of cervical carcinoma by “Pap smear” and suggests its utility a ...
Using the NAACCR Geocoder to Perform In
Using the NAACCR Geocoder to Perform In

lecture15hs
lecture15hs

Ten years of progress in radiation oncology COMMENTARY Open Access Dirk Vordermark
Ten years of progress in radiation oncology COMMENTARY Open Access Dirk Vordermark

Breast Cancer Research - Law Offices of Diana Santa Maria
Breast Cancer Research - Law Offices of Diana Santa Maria

... cancer. However, her research did reveal that weight loss of 10 or more pounds that was maintained over at least 5 years might reduce breast cancer risk among postmenopausal women. ...
South West Queensland region
South West Queensland region

... Disclaimer: The information in this publication should not be used as a substitute for advice from a properly qualified medical professional who can advise you about your own individual medical needs. It is not intended to constitute medical advice and is provided for general information purposes on ...
Urban/rural disparities in cancer incidence in New York
Urban/rural disparities in cancer incidence in New York

... other locations. Previous research on the relationship between prostate cancer and urban/rural residence has not been consistent, with some studies reporting a positive association with urban, some with rural, and some reporting no relationship [11]. However, several potential contributing factors t ...
Real-Time Intra-Fraction Motion Management During Radiation
Real-Time Intra-Fraction Motion Management During Radiation

... prostate cancer, use of a rectal balloon has been reported to improve consistent positioning of the prostate and thus reduce rectal tissue irradiation during radiation therapy. In addition, more sophisticated imaging techniques, including use of implanted fiducial markers, have been used to better p ...
Src as a therapeutic target in men with prostate cancer and bone
Src as a therapeutic target in men with prostate cancer and bone

... mutants of src were effective, suggesting that Src recruits and/or activates downstream kinases [21]. Various in vitro studies using inhibitors of Src were consistent with its integral role in osteoclast function [22–25]. Lastly, suppression of Src also interfered with chloride-channel transport and ...
Us TOO University Presents: Estrogen Deficiency Side Effects Due
Us TOO University Presents: Estrogen Deficiency Side Effects Due

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Prostate-specific antigen

Prostate-specific antigen (PSA), also known as gamma-seminoprotein or kallikrein-3 (KLK3), is a glycoprotein enzyme encoded in humans by the KLK3 gene. PSA is a member of the kallikrein-related peptidase family and is secreted by the epithelial cells of the prostate gland. PSA is produced for the ejaculate, where it liquefies semen in the seminal coagulum and allows sperm to swim freely. It is also believed to be instrumental in dissolving cervical mucus, allowing the entry of sperm into the uterus.PSA is present in small quantities in the serum of men with healthy prostates, but is often elevated in the presence of prostate cancer or other prostate disorders. The United States Preventive Services Task Force (USPSTF, 2012) does not recommend PSA screening, noting that the test may result in “overdiagnosis” and “overtreatment” because ""most prostate cancer is asymptomatic for life"" and treatments involve risks of complications including impotence (erectile dysfunction) and incontinence. The USPSTF concludes ""the potential benefit does not outweigh the expected harms."" PSA is not a unique indicator of prostate cancer, but may also detect prostatitis or benign prostatic hyperplasia. 30 percent of patients with high PSA have prostate cancer diagnosed after biopsy.
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