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Hormone therapy - The Prostate Cancer Charity
Hormone therapy - The Prostate Cancer Charity

... There are three main ways to have hormone therapy for prostate cancer. These are: • injections or implants to stop your testicles making testosterone • tablets to block the effects of testosterone • surgery to remove the testicles or the parts of the testicles that make testosterone. This is call ...
Animal Models of Human Prostate Cancer: The
Animal Models of Human Prostate Cancer: The

... that may depend on the underlying biology of the genetic alteration, the exact constructs used for expression, the site(s) of integration of transgenes, and the mouse strain. It is the opinion of the panel that it is premature to conclude that lesions in any given lobe are more representative of hum ...
Mission Moments - Relay For Life
Mission Moments - Relay For Life

... f. Any of the above – Beginning at age 50, men and women should begin screening with on of the examination schedules above. People who are at moderate or high risk for colorectal cancer should talk with a doctor about a different testing schedule. 8. Colon cancer usually causes no symptoms in its ea ...
International Union Against Cancer Introducing UICC What we do A
International Union Against Cancer Introducing UICC What we do A

... touched by cancer – either directly, as a person living with the disease, or through a family member or friend. More than 11 million new cases are diagnosed each year, and about 8 million people die from cancer – over 70% of them in low- and middle-income countries. Based on current trends, 15.5 mil ...
Cancer Incidence in Wales 2015 FINAL
Cancer Incidence in Wales 2015 FINAL

... Wales occurred in the over 65 year-olds in 2015. And the highest cancer rates are seen in older age-groups, especially men. Although the risk of most types of cancer increases with ageing - such as the most common cancers (breast, prostate, lung and bowel) - some rarer types of cancer are more commo ...
radiation therapy oncology group
radiation therapy oncology group

... * 32 months chosen because RTOG 9202 used 28 months and EORTC used 36 months = avg 32 months Note: As this protocol allows for treatment with exclusively EBRT or EBRT + brachytherapy (at the discretion of the treating physician), this must be specified at the time of study enrollment. Should a patie ...
Print this article
Print this article

... contains hundreds of studies about the effects of exercise in people who have been diagnosed with cancer (that is, cancer survivors), which have spawned dozens of systematic reviews, several international guidelines, and calls for the integration of exercise programs into clinical and community canc ...
The role and status of population-based cancer registration
The role and status of population-based cancer registration

WE CAN. I CAN. - World Cancer Day
WE CAN. I CAN. - World Cancer Day

... Twitter for example, not only does World Cancer Day continue to grow in high-level figures, but its impact is increasing also, with over 900 events taking place in 129 countries. It has become ‘the’ platform for the launch of meaningful initiatives, announcements and events, not only by organisation ...
Prostate Cancer - 2012 Report on Cancer Statistics in Alberta
Prostate Cancer - 2012 Report on Cancer Statistics in Alberta

... specific population. In this section of the report, incidence counts refer to the number of new prostate cancer diagnoses in Alberta residents in a calendar year. Incidence rates are the number of new cancer cases diagnosed per 100,000 population in a specific time period. Mortality counts describe ...
cancer control program - Pennsylvania Department of Health
cancer control program - Pennsylvania Department of Health

... emotional toll on individuals and families and creating an enormous drain on the Commonwealth's medical and health resources. To combat tobacco use and treat tobacco related illness, the Commonwealth has invested in state tobacco prevention and control programs that are comprehensive and make use of ...
Novel diagnostic biomarkers for prostate cancer
Novel diagnostic biomarkers for prostate cancer

... earlier age (4). Consequently, much effort is being placed on detecting prostate cancer in an early, curable stage to decrease the rate of mortality from this disease. Along with genetics, social and environmental factors (especially diet and lifestyle) may act as the determining factors, which may ...
MP 8.01.11 Brachytherapy for Clinically Localized Prostate Cancer
MP 8.01.11 Brachytherapy for Clinically Localized Prostate Cancer

... seeds become dislodged and travel to nearby organs such as the bladder or lung. While this has been reported in 6% to 55% of patients, reports of harm are limited to individual case studies. Brachytherapy used as monotherapy The vast majority of the data on brachytherapy consists of uncontrolled cas ...
Autoantibody Cancer Biomarker: Extracellular Protein
Autoantibody Cancer Biomarker: Extracellular Protein

... enzymatic assay exhibited 83% sensitivity and 80% specificity, with an area under the curve (AUC) of 0.86938 (compared with the autoantibody EIA AUC of 0.93675; Fig. 3). These results show that the ECPKA autoantibody EIA did better than the enzymatic assay in distinguishing between patients with can ...
Understanding Prostate Cancer
Understanding Prostate Cancer

turn it purple - Pancreatic Cancer Action
turn it purple - Pancreatic Cancer Action

... earlier diagnosis and more effective treatments for pancreatic cancer. Every year, almost 9,000 men and women will be newly diagnosed with pancreatic cancer and due to late diagnosis, they will be faced with a shockingly low three per cent chance of survival and an average life expectancy of just th ...
This tool contains a summary of the NICE referral guidelines for
This tool contains a summary of the NICE referral guidelines for

... with a normal prostate, but rising/raised age-specific PSA, with or without lower urinary tract symptoms. (In patients compromised by other comorbidities, a discussion with the patient or carers and/or a specialist may be more appropriate.) ...
Prostate Imaging Clinical Compendium ®
Prostate Imaging Clinical Compendium ®

maintaining health androgen deprivation therapy
maintaining health androgen deprivation therapy

... FDA approval of multiple exciting new treatments for advanced prostate cancer, long-term ADT remains—and is likely to remain—the cornerstone of treatment. Clinicians routinely care for men taking these drugs for ten, and in some cases, 20 years. We have an increasing body of knowledge that suggests ...
March Is National Colorectal Cancer Awareness Month
March Is National Colorectal Cancer Awareness Month

... cause of cancer-related deaths in the United States when men and women are considered separately, and the second leading cause when both sexes are combined. In 2016, it is estimated that 134,490 new cases will be diagnosed, and 49,190 people will die from colorectal cancer. ...
Seasonality pattern of breast, colorectal, and prostate cancer is
Seasonality pattern of breast, colorectal, and prostate cancer is

... did not show any overall seasonality in cumulative probability of death from breast cancer [30]. Interestingly, a seasonal variation in tumor stage at the time of diagnosis was detected by the authors, with spring having the highest proportion of localized tumors. Cancers such as breast cancer are u ...
Appropriate Use Criteria for Bone Scintigraphy in Prostate and
Appropriate Use Criteria for Bone Scintigraphy in Prostate and

... using the U.S. Preventive Services Task Force criteria (for randomized trials and cohort studies) (20), QUADAS-2 (for diagnostic accuracy studies) (21), and AMSTAR (for systematic reviews) (22). The strength of overall evidence was graded as high, moderate, low, or very low using methods based on qu ...
Androgens and androgen receptor signaling in prostate tumorigenesis
Androgens and androgen receptor signaling in prostate tumorigenesis

... homeostasis has been well reviewed (Litvinov et al. 2003, Marker et al. 2003). Briefly, the androgens testosterone, produced by the fetal testis, and dihydrotestosterone (DHT), produced by local conversion of circulating testosterone by 5a-reductase, act to specify the development of the urogenital ...


STRANG National Cancer Prevention Month 2.16 FINAL.pub
STRANG National Cancer Prevention Month 2.16 FINAL.pub

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Prostate-specific antigen

Prostate-specific antigen (PSA), also known as gamma-seminoprotein or kallikrein-3 (KLK3), is a glycoprotein enzyme encoded in humans by the KLK3 gene. PSA is a member of the kallikrein-related peptidase family and is secreted by the epithelial cells of the prostate gland. PSA is produced for the ejaculate, where it liquefies semen in the seminal coagulum and allows sperm to swim freely. It is also believed to be instrumental in dissolving cervical mucus, allowing the entry of sperm into the uterus.PSA is present in small quantities in the serum of men with healthy prostates, but is often elevated in the presence of prostate cancer or other prostate disorders. The United States Preventive Services Task Force (USPSTF, 2012) does not recommend PSA screening, noting that the test may result in “overdiagnosis” and “overtreatment” because ""most prostate cancer is asymptomatic for life"" and treatments involve risks of complications including impotence (erectile dysfunction) and incontinence. The USPSTF concludes ""the potential benefit does not outweigh the expected harms."" PSA is not a unique indicator of prostate cancer, but may also detect prostatitis or benign prostatic hyperplasia. 30 percent of patients with high PSA have prostate cancer diagnosed after biopsy.
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