The rational use of nucleic acid amplification testing for the
... NAAT is very expensive and unnecessary testing is a poor use of available ...
... NAAT is very expensive and unnecessary testing is a poor use of available ...
Prescription Drugs: Abuse and Addiction
... a prescription, in a way other than as prescribed, or for the experience or feelings elicited. According to several national surveys, prescription medications, such as those used to treat pain, attention deficit disorders, and anxiety, are being abused at a rate second only to marijuana among illici ...
... a prescription, in a way other than as prescribed, or for the experience or feelings elicited. According to several national surveys, prescription medications, such as those used to treat pain, attention deficit disorders, and anxiety, are being abused at a rate second only to marijuana among illici ...
Evaluation of Efficacy and Safety of Cystone Syrup in Lower Ureteric
... about the study drug, its effects, duration of stay in the trial and overall plan of the study. A written informed consent was obtained. The history was noted by interviewing each patient. Thorough clinical examination and symptomatic evaluation was carried out and the details were noted down in the ...
... about the study drug, its effects, duration of stay in the trial and overall plan of the study. A written informed consent was obtained. The history was noted by interviewing each patient. Thorough clinical examination and symptomatic evaluation was carried out and the details were noted down in the ...
Therapeutic Drug Monitoring of Antiepileptic Drugs in the 21st Century
... known. Ideal candidate drugs are those with significant inter-individual pharmacokinetic (PK) variability, low intra-individual PK variability and a good correlation between blood level and clinical response or side effects. Although the clinical contribution of TDM for some older antiepileptic drug ...
... known. Ideal candidate drugs are those with significant inter-individual pharmacokinetic (PK) variability, low intra-individual PK variability and a good correlation between blood level and clinical response or side effects. Although the clinical contribution of TDM for some older antiepileptic drug ...
Handedness, Footedness, Eyedness
... Summary of Cognitive Effects All of the AEDs produce some cognitive side effects. However, when used in monotherapy with anticonvulsant blood levels within the standard therapeutic ranges, these effects are modest. There is no convincing evidence at this time of clinically significant differential c ...
... Summary of Cognitive Effects All of the AEDs produce some cognitive side effects. However, when used in monotherapy with anticonvulsant blood levels within the standard therapeutic ranges, these effects are modest. There is no convincing evidence at this time of clinically significant differential c ...
Saquinavir/low dose ritonavir - WHO archives
... around 40 million persons world-wide are infected with HIV and more than 90% of infected persons live in the developing world. Growing experience of the provision of anti-retroviral therapy in resource-poor settings (eg. Brazil, Côte d’Ivoire, Senegal, Haiti, India) indicates that treatment can be p ...
... around 40 million persons world-wide are infected with HIV and more than 90% of infected persons live in the developing world. Growing experience of the provision of anti-retroviral therapy in resource-poor settings (eg. Brazil, Côte d’Ivoire, Senegal, Haiti, India) indicates that treatment can be p ...
What are Predatory Drugs
... drugs are invisible and odorless when dissolved in water. They are somewhat salty tasting, but are indiscernible when dissolved in beverages such as sodas, juice, liquor, or beer. ...
... drugs are invisible and odorless when dissolved in water. They are somewhat salty tasting, but are indiscernible when dissolved in beverages such as sodas, juice, liquor, or beer. ...
the facts on marijuana
... This means they contain dozens, if not hundreds, of other physiologically active compounds which are irrelevant to their palliative effects and may actually work at cross-purposes against those effects. For example, many people believe alcohol and nicotine lower their stress level, but in fact these ...
... This means they contain dozens, if not hundreds, of other physiologically active compounds which are irrelevant to their palliative effects and may actually work at cross-purposes against those effects. For example, many people believe alcohol and nicotine lower their stress level, but in fact these ...
Toxicology and safety pharmacology and metabolic studies
... Typical 1 month study – tissues examined ...
... Typical 1 month study – tissues examined ...
Chronic potassium iodide therapy caused remission in about half of
... are effective in controlling the hyperthyroidism in patients with Graves’ disease but can produce allergic responses. When that happens, the only other options are surgery to remove the thyroid or radioactive iodine therapy to destroy the thyroid. Stable iodine has been used to treat hyperthyroidism ...
... are effective in controlling the hyperthyroidism in patients with Graves’ disease but can produce allergic responses. When that happens, the only other options are surgery to remove the thyroid or radioactive iodine therapy to destroy the thyroid. Stable iodine has been used to treat hyperthyroidism ...
Review Pharmacodynamic and pharmacokinetic interactions
... Though certain problems may occur when both types of medicines are taken together, they have not been adequately analyzed. It was reported that anticoagulation was enhanced in addition to bleeding when patients took long-term warfarin therapy in combination with Salvia miltiorrhiza (danshen), and la ...
... Though certain problems may occur when both types of medicines are taken together, they have not been adequately analyzed. It was reported that anticoagulation was enhanced in addition to bleeding when patients took long-term warfarin therapy in combination with Salvia miltiorrhiza (danshen), and la ...
a paper on crystal methamphetamine
... early stages of Crystal Meth addiction it may be a lot of fun for the user, because the molecular structure is more stimulating to the brain than any other substance. The high, lasting from about 10-12 hours with one usage lasts a lot longer than other stimulants, like cocaine. It is generally cheap ...
... early stages of Crystal Meth addiction it may be a lot of fun for the user, because the molecular structure is more stimulating to the brain than any other substance. The high, lasting from about 10-12 hours with one usage lasts a lot longer than other stimulants, like cocaine. It is generally cheap ...
Chapter 1 - Introduction to Psychopharmacology MULTIPLE
... 27. Dr. Lopez designs a clinical trial: • Group A will receive a placebo • Group B will receive Drug X-low dose • Group C will receive Drug X-high dose • Blood pressure will be measured four times for each participant This is an example of what type of study design? a. One-arm design: only one physi ...
... 27. Dr. Lopez designs a clinical trial: • Group A will receive a placebo • Group B will receive Drug X-low dose • Group C will receive Drug X-high dose • Blood pressure will be measured four times for each participant This is an example of what type of study design? a. One-arm design: only one physi ...
Optimal Use of Bendamustine in Chronic Lymphocytic Leukemia
... Bendamustine is a novel bifunctional alkylating agent with promising activity in lymphoid malignancies and several solid tumors. Unfortunately, the early development of this agent did not provide sufficient information on which to determine an optimal systematic dose and schedule. As a result, admini ...
... Bendamustine is a novel bifunctional alkylating agent with promising activity in lymphoid malignancies and several solid tumors. Unfortunately, the early development of this agent did not provide sufficient information on which to determine an optimal systematic dose and schedule. As a result, admini ...
Impact of Single Nucleotide Polymorphisms (SNPs) on
... Figure 4. Mycophenolic acid blood concentration in relation to other associated SNPs. Mycophenolic acid corrected (dose/weight) trough concentrations (C0/Dc, ((ng/mL)/(mg/kg/ 24 h))) are plotted (mean and standard deviation of all the measurements in each period) in relation to the SLCO1B1 rs2306283 ...
... Figure 4. Mycophenolic acid blood concentration in relation to other associated SNPs. Mycophenolic acid corrected (dose/weight) trough concentrations (C0/Dc, ((ng/mL)/(mg/kg/ 24 h))) are plotted (mean and standard deviation of all the measurements in each period) in relation to the SLCO1B1 rs2306283 ...
Antibioticss
... - Useful against anaerobic bacteria, so can be used in odontogenic infections. - Staining of developing teeth when used in pregnant, or lactating women, or in children. - Have anticollagenase effect so, can be used in periodontal and peri-implant diseases ...
... - Useful against anaerobic bacteria, so can be used in odontogenic infections. - Staining of developing teeth when used in pregnant, or lactating women, or in children. - Have anticollagenase effect so, can be used in periodontal and peri-implant diseases ...
Opioid Substition Therapy - California Opioid Maintenance Providers
... Partial agonist: ceiling effect Expensive: $300/month at average dose Not interchangeable with methadone ...
... Partial agonist: ceiling effect Expensive: $300/month at average dose Not interchangeable with methadone ...
Excess mortality in patients with asthma on long-acting b -agonists 2
... asthma-related deaths (13 versus three cases, RR 4.4). The NNH for death of any cause was 1,316 for patients treated for 28 weeks with salmeterol. In an attempt to explain the results of SMART, the authors, two of them employees of the sponsor, argued that the imbalance of the end-points occurred la ...
... asthma-related deaths (13 versus three cases, RR 4.4). The NNH for death of any cause was 1,316 for patients treated for 28 weeks with salmeterol. In an attempt to explain the results of SMART, the authors, two of them employees of the sponsor, argued that the imbalance of the end-points occurred la ...
Product Monograph
... As with other triptans, eletriptan has been associated with transient pain or pressure sensation in the chest or throat. Because of the potential of 5-HT1 agonists to cause coronary vasospasm, eletriptan should not be given to patients with documented ischemic or vasospastic coronary artery disease ...
... As with other triptans, eletriptan has been associated with transient pain or pressure sensation in the chest or throat. Because of the potential of 5-HT1 agonists to cause coronary vasospasm, eletriptan should not be given to patients with documented ischemic or vasospastic coronary artery disease ...
g 0 pH 7.2
... above-mentioned characteristic [1], [2], or [3] is particu 60 dissolved in an organic solvent; the obtained solution is spray coated on ?ne particle nuclei (e. g. by flow coating larly difficult to prepare in long acting form and such or ?uidized layer coating) followed by drying; the dried drug is ...
... above-mentioned characteristic [1], [2], or [3] is particu 60 dissolved in an organic solvent; the obtained solution is spray coated on ?ne particle nuclei (e. g. by flow coating larly difficult to prepare in long acting form and such or ?uidized layer coating) followed by drying; the dried drug is ...
Sample Chapter
... is very important to the clinician as current dosing in geriatric patients is often based on broad generalizations such as “use one third to one half the usual dose,” or anecdotal data—not on solid pharmacokinetic or pharmacodynamic studies. Pharmacokinetic and/or pharmacodynamic differences in olde ...
... is very important to the clinician as current dosing in geriatric patients is often based on broad generalizations such as “use one third to one half the usual dose,” or anecdotal data—not on solid pharmacokinetic or pharmacodynamic studies. Pharmacokinetic and/or pharmacodynamic differences in olde ...
159 - ASIPP
... 214. The states of a patient in which repetitions of the same dose of a drug has progressively less effect or in which the dose needs to be increased to obtain the same degree of pharmacological effect as was caused by the original dose is defined as: A. Physical dependence B. Synergistic effect C. ...
... 214. The states of a patient in which repetitions of the same dose of a drug has progressively less effect or in which the dose needs to be increased to obtain the same degree of pharmacological effect as was caused by the original dose is defined as: A. Physical dependence B. Synergistic effect C. ...
Bad Pharma
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Bad Pharma: How Drug Companies Mislead Doctors and Harm Patients is a book by British physician and academic Ben Goldacre about the pharmaceutical industry, its relationship with the medical profession, and the extent to which it controls academic research into its own products. The book was published in September 2012 in the UK by the Fourth Estate imprint of HarperCollins, and in February 2013 in the United States by Faber and Faber.Goldacre argues in the book that ""the whole edifice of medicine is broken"" because the evidence on which it is based is systematically distorted by the pharmaceutical industry. He writes that the industry finances most of the clinical trials into its own products and much of doctors' continuing education, that clinical trials are often conducted on small groups of unrepresentative subjects and negative data is routinely withheld, and that apparently independent academic papers may be planned and even ghostwritten by pharmaceutical companies or their contractors, without disclosure. Goldacre calls the situation a ""murderous disaster,"" and makes suggestions for action by patients' groups, physicians, academics and the industry itself.Responding to the book's publication, the Association of the British Pharmaceutical Industry issued a statement arguing that the examples the book offers are historical, that the concerns have been addressed, that the industry is among the most regulated in the world, and that it discloses all data in accordance with international standards.In January 2013 Goldacre joined the Cochrane Collaboration, British Medical Journal and others in setting up AllTrials, a campaign calling for the results of all past and current clinical trials to be reported. The British House of Commons Public Accounts Committee expressed concern in January 2014 that drug companies were still only publishing around 50 percent of clinical-trial results.