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Myochrysine (sodium aurothiolamate)
Myochrysine (sodium aurothiolamate)

... The predominant clinical effect of MYOCHRYSINE (sodium aurothiomalate) appears to be suppression of the synovitis in the active stage of the rheumatoid disease. The precise mechanism of action is unknown but it has been suggested that the drug may act by inhibiting cell-mediated and humoral immune m ...
Clinical Overview of Omacor - American Journal of Cardiology
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... Figure 1. Process of manufacturing Omacor. (Reprinted with permission from Solvay Healthcare Limited.21) ...
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New Drugs and Technologies
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... reviewed at the time of initial approval demonstrated that sibutramine led to a placebo-adjusted mean weight loss of approximately 4%, with twice as many patients (responders) losing at least 5% of baseline body weight as those randomized to placebo, consistent with the newer FDA guideline for obesi ...
Antiviral drugs
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... and inhibit a specific viral protein, most often an enzyme involved in viral nucleic acid synthesis. - Single nucleotide changes leading to critical amino acid substitutions in a target protein often are sufficient to cause antiviral drug resistance. - Current agents inhibit active replication but d ...
Oral Disease-Modifying Therapies for Multiple Sclerosis
Oral Disease-Modifying Therapies for Multiple Sclerosis

... MS (RRMS) was first documented in a 6-month, double-blind, phase II core study and a 6-month extension study, during which both investigators and patients were unaware of the treatment assignments.13 The median total numbers of gadolinium-enhanced lesions decreased with fingolimod treatment at both ...
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... actual results and developments to differ materially from those expressed or implied. The significant risks related to SkyePharma’s business which could cause our actual results and developments to differ materially from those forwardlooking statements are discussed in SkyePharma’s SEC filings under ...
Peer Education Training Manual
Peer Education Training Manual

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Key issues in Chronic Heart Failure Chronic Heart Failure (CHF)



... in 0.5N HCl by sonicating for 10 minutes. The volume was made up  to  mark  to  get  final  concentration  of  100μg/ml.  The  solution  was  then  filtered  through  Whatmann  filter  paper  (no.41).  This  solution  was used as stock solution.   The  working  solution  of  drug  (40μg/ml)  was  pr ...
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Protonil Tablet - Renata Limited

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... therapy, the difference wasn’t significant. The IVAN study group also conducted a meta analysis by including one-year data from CATT, again with similar results. In the second year of the CATT study, a group of subjects receiving monthly treatments were randomized to the p.r.n. regimen, allowing inv ...
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the side effects of common psychiAtric drugs internAtionAl

... hallucinations, suicidal ideation, psychotic behavior, aggression and violent behavior.5 September 13, 2005: The Oregon Health & Science University, Evidence-Based Practice Center published the findings of its review of 2,287 studies—virtually every study ever conducted on ADHD drugs—and found that ...
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Syllabus Fall 2016

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Methotrexate - Wolverhampton Formulary

... This shared care agreement outlines suggested ways in which the responsibilities for managing the prescribing of methotrexate for ocular inflammatory diseases can be shared between the specialist and general practitioner (GP). GPs are invited to participate. If the GP is not confident to undertake t ...
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Drug/Alcohol Addiction… - Neuroscienze e Dipendenze

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Treatment of walking impairment in multiple sclerosis with

... The original United States Adopted Name (USAN) for 4-AP was fampridine. The US Food and Drug Administration (FDA), at the time of approval of the drug in MS, required the name to be changed to avoid potential confusion with the existing drug famotidine. The name dalfampridine was proposed to the USA ...
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Bad Pharma



Bad Pharma: How Drug Companies Mislead Doctors and Harm Patients is a book by British physician and academic Ben Goldacre about the pharmaceutical industry, its relationship with the medical profession, and the extent to which it controls academic research into its own products. The book was published in September 2012 in the UK by the Fourth Estate imprint of HarperCollins, and in February 2013 in the United States by Faber and Faber.Goldacre argues in the book that ""the whole edifice of medicine is broken"" because the evidence on which it is based is systematically distorted by the pharmaceutical industry. He writes that the industry finances most of the clinical trials into its own products and much of doctors' continuing education, that clinical trials are often conducted on small groups of unrepresentative subjects and negative data is routinely withheld, and that apparently independent academic papers may be planned and even ghostwritten by pharmaceutical companies or their contractors, without disclosure. Goldacre calls the situation a ""murderous disaster,"" and makes suggestions for action by patients' groups, physicians, academics and the industry itself.Responding to the book's publication, the Association of the British Pharmaceutical Industry issued a statement arguing that the examples the book offers are historical, that the concerns have been addressed, that the industry is among the most regulated in the world, and that it discloses all data in accordance with international standards.In January 2013 Goldacre joined the Cochrane Collaboration, British Medical Journal and others in setting up AllTrials, a campaign calling for the results of all past and current clinical trials to be reported. The British House of Commons Public Accounts Committee expressed concern in January 2014 that drug companies were still only publishing around 50 percent of clinical-trial results.
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