Germinating seeds of the mung bean, Vigna radiata (Fabaceae), as
... present study we have evaluated the possibility of using the germinating mung beans (Vigna radiata), for rapid and inexpensive screening of drugs exhibiting cytotoxic properties. Mung beans were allowed to germinate either in tap water or in different drug solutions, and parameters like percent germ ...
... present study we have evaluated the possibility of using the germinating mung beans (Vigna radiata), for rapid and inexpensive screening of drugs exhibiting cytotoxic properties. Mung beans were allowed to germinate either in tap water or in different drug solutions, and parameters like percent germ ...
Formulation Design and Characterization of Kollidon SR Based
... the following 7 hours. At specific time interval 5 mL of medium was withdrawn for measuring the drug release and in every case 5 mL of fresh buffer was substituted to maintain the volume constant. After filtration, the amount of Trimetazidine Dihydrochloride in each sample was determined spectrophot ...
... the following 7 hours. At specific time interval 5 mL of medium was withdrawn for measuring the drug release and in every case 5 mL of fresh buffer was substituted to maintain the volume constant. After filtration, the amount of Trimetazidine Dihydrochloride in each sample was determined spectrophot ...
Information on benefit-risk of medicines: patients`, consumers` and
... by assessing the results of scientific tests and studies that pharmaceutical companies are legally required to perform according to internationally agreed scientific standards, to show the efficacy and safety of a medicine for obtaining a marketing authorisation. The many facets of benefit-risk The ...
... by assessing the results of scientific tests and studies that pharmaceutical companies are legally required to perform according to internationally agreed scientific standards, to show the efficacy and safety of a medicine for obtaining a marketing authorisation. The many facets of benefit-risk The ...
milk thistle in liver diseases: past, present, future
... serpents”. Another famous ancient herbalist, Pliny the Elder, wrote that mixing the juice of the plant with honey was good for “carrying off bile” (Ross, 2008). ...
... serpents”. Another famous ancient herbalist, Pliny the Elder, wrote that mixing the juice of the plant with honey was good for “carrying off bile” (Ross, 2008). ...
Sept-Oct 2015
... (versus no alcohol) supports previous research; the findings of no significant effect from lower levels of intake are consistent with either a slight increase or a slight decrease in blood pressure among people with the participants’ baseline level of alcohol consumption. It is not known how the eff ...
... (versus no alcohol) supports previous research; the findings of no significant effect from lower levels of intake are consistent with either a slight increase or a slight decrease in blood pressure among people with the participants’ baseline level of alcohol consumption. It is not known how the eff ...
View PDF - European Heart Journal - Quality of Care and Clinical
... Evidence that one myocardial revascularisation strategy is clinically and economically superior is lacking, and in this context the choice of strategy for individual patients will depend on the clinical circumstances, angiographic pattern of disease, local policy and patient preference. In discussio ...
... Evidence that one myocardial revascularisation strategy is clinically and economically superior is lacking, and in this context the choice of strategy for individual patients will depend on the clinical circumstances, angiographic pattern of disease, local policy and patient preference. In discussio ...
Colic Pain Management - Hagyard Equine Medical Institute
... banamine is to provide relief in patients with mild to moderate colic pain when a period of "extended observation" is desired. Butorphanol can provide 30-45 minutes of relief in patients with moderate colic pain, and somewhat longer relief in patients with milder symptoms. Butorphanol should not be ...
... banamine is to provide relief in patients with mild to moderate colic pain when a period of "extended observation" is desired. Butorphanol can provide 30-45 minutes of relief in patients with moderate colic pain, and somewhat longer relief in patients with milder symptoms. Butorphanol should not be ...
NIDA Research Report - Hallucinogens and
... altering distribution of the neurotransmitter glutamate throughout the brain. Glutamate is involved in perception of pain, responses to the environment, and memory. rugs such as PCP (phenPCP is considered the typical cyclidine) and ketamine, dissociative drug, and the which were initially descriptio ...
... altering distribution of the neurotransmitter glutamate throughout the brain. Glutamate is involved in perception of pain, responses to the environment, and memory. rugs such as PCP (phenPCP is considered the typical cyclidine) and ketamine, dissociative drug, and the which were initially descriptio ...
How to withdraw - Surviving Antidepressants
... Withdrawal and dependence are physical phenomena. Even totally normal people given SSRIs for 2-3 weeks can have anxiety and depression when they try to stop. This is not an anxiety or mood disorder that responds to psychotherapy or cognitive therapy. But if you become anxious, you will be hypervigil ...
... Withdrawal and dependence are physical phenomena. Even totally normal people given SSRIs for 2-3 weeks can have anxiety and depression when they try to stop. This is not an anxiety or mood disorder that responds to psychotherapy or cognitive therapy. But if you become anxious, you will be hypervigil ...
for immediate release
... • Vancomycin is effective in the treatment of staphylococcal endocarditis. Vancomycin has been reported to be effective alone or in combination with an aminoglycoside for endocarditis caused by Streptococcus viridans or S. bovis. For endocarditis caused by enterococci (e.g., E. faecalis), vancomycin ...
... • Vancomycin is effective in the treatment of staphylococcal endocarditis. Vancomycin has been reported to be effective alone or in combination with an aminoglycoside for endocarditis caused by Streptococcus viridans or S. bovis. For endocarditis caused by enterococci (e.g., E. faecalis), vancomycin ...
IN-VITRO STUDIES OF EFAVIRENZ FORMULATION BY RP-HPLC Research Article
... Efavirenz is a non-nucleoside reverse transcriptase inhibitor (NNRTI) and is used as a part of highly active anti-retroviral therapy (HAART) for the treatment of human immunodeficiency virus (HIV1). It is chemically (4S)-6-chloro -4- (cyclopropylethynyl)-1, 4dihydro-4- (trifluoromethyl) - 2H-3, 1-be ...
... Efavirenz is a non-nucleoside reverse transcriptase inhibitor (NNRTI) and is used as a part of highly active anti-retroviral therapy (HAART) for the treatment of human immunodeficiency virus (HIV1). It is chemically (4S)-6-chloro -4- (cyclopropylethynyl)-1, 4dihydro-4- (trifluoromethyl) - 2H-3, 1-be ...
10. review of literature
... 2.1.14. Aschkenasy et al., 2005 have worked on osmotically swollen hydrophobic matrices of Salicylic acid to see on-demand release by ultrasound from osmotically swollen hydrophobic matrices by using EVA copolymer, methylene chloride and NaCl. They observed that swollen matrices had a high response ...
... 2.1.14. Aschkenasy et al., 2005 have worked on osmotically swollen hydrophobic matrices of Salicylic acid to see on-demand release by ultrasound from osmotically swollen hydrophobic matrices by using EVA copolymer, methylene chloride and NaCl. They observed that swollen matrices had a high response ...
Bactroban cream
... reproduction studies are not always predictive of human response, this drug should be used during pregnancy only if clearly needed. ...
... reproduction studies are not always predictive of human response, this drug should be used during pregnancy only if clearly needed. ...
Outsourcing API Manufacture to India & China A Suppliers Perspective
... Over 20 years experience 6 sites (3 in Switzerland, 1 in the United Kingdom, 1 in France and 1 in India) Over 200 chemists, with >40% Ph.D. Well over 500 projects per annum ...
... Over 20 years experience 6 sites (3 in Switzerland, 1 in the United Kingdom, 1 in France and 1 in India) Over 200 chemists, with >40% Ph.D. Well over 500 projects per annum ...
Renagel (sevelamer hydrochloride)
... Closer monitoring of TSH levels is therefore recommended for patients receiving both medications. When administering any other medication where a reduction in the bioavailability of that medication would have a clinically significant effect on safety or efficacy, the physician should consider monito ...
... Closer monitoring of TSH levels is therefore recommended for patients receiving both medications. When administering any other medication where a reduction in the bioavailability of that medication would have a clinically significant effect on safety or efficacy, the physician should consider monito ...
Antivirals
... In some countries, Relenza® may also be used as prophylaxis to prevent infection either before or after exposure to influenza. The usual preventative dose is an inhalation of two “blisters” (10mg).once a day, for 10 days following exposure or for the duration of exposure. ...
... In some countries, Relenza® may also be used as prophylaxis to prevent infection either before or after exposure to influenza. The usual preventative dose is an inhalation of two “blisters” (10mg).once a day, for 10 days following exposure or for the duration of exposure. ...
Drug alerts - National Treatment Agency
... or built the requirement into service specifications, while others have bought in outside expertise or used existing staff resources. It may be appropriate and cost effective for an LDIS co-ordinator to cover several local areas depending on geography and local considerations. The role should not be ...
... or built the requirement into service specifications, while others have bought in outside expertise or used existing staff resources. It may be appropriate and cost effective for an LDIS co-ordinator to cover several local areas depending on geography and local considerations. The role should not be ...
PRACTICAL THERAPEUTICS Drugs 45 (6): 918
... subgroups reflect entities with different pathophysiologies. These are shown in table I. However, patients with true GORD are likely to account for most cases of so-called reflux-like dyspepsia, and such cases have probably often been included in therapeutic trials of functional dyspepsia. It is wel ...
... subgroups reflect entities with different pathophysiologies. These are shown in table I. However, patients with true GORD are likely to account for most cases of so-called reflux-like dyspepsia, and such cases have probably often been included in therapeutic trials of functional dyspepsia. It is wel ...
HIGHLIGHTS OF PRESCRIBING INFORMATION ----------------------- WARNINGS AND PRECAUTIONS -----------------------
... C. Due to the small number of co-infected subjects studied, no conclusions can be drawn regarding whether they are at an increased risk for hepatic adverse events with administration of SELZENTRY. ...
... C. Due to the small number of co-infected subjects studied, no conclusions can be drawn regarding whether they are at an increased risk for hepatic adverse events with administration of SELZENTRY. ...
Antileishmanial activity of HIV protease inhibitors
... opportunistic infection [1], particularly in patients infected with human immunodeficiency virus (HIV), has given rise to the need for new therapeutic strategies. The control of leishmania infection is T-cell dependent and requires a Th1 response. There has therefore been an increased incidence of k ...
... opportunistic infection [1], particularly in patients infected with human immunodeficiency virus (HIV), has given rise to the need for new therapeutic strategies. The control of leishmania infection is T-cell dependent and requires a Th1 response. There has therefore been an increased incidence of k ...
Group 1 - Random Sampling
... 1. To determine the loss of righting reflex after injection of intravenous and intramuscular ketamine on rabbits. 2. To statistically compare the latency and duration of the loss of righting reflex upon administration of intravenous and intramuscular ketamine in rabbits. 3. To review and observe the ...
... 1. To determine the loss of righting reflex after injection of intravenous and intramuscular ketamine on rabbits. 2. To statistically compare the latency and duration of the loss of righting reflex upon administration of intravenous and intramuscular ketamine in rabbits. 3. To review and observe the ...
Research Report Series
... Injection drug users (IDUs) are the highest-risk group for acquiring hepatitis C (HCV) infection and continue to drive the escalating HCV epidemic: Each IDU infected with HCV is likely to infect 20 other people.17 Of the 17,000 new HCV infections occurring in the United States in 2010, over half (53 ...
... Injection drug users (IDUs) are the highest-risk group for acquiring hepatitis C (HCV) infection and continue to drive the escalating HCV epidemic: Each IDU infected with HCV is likely to infect 20 other people.17 Of the 17,000 new HCV infections occurring in the United States in 2010, over half (53 ...
Full Text PDF - Science and Education Publishing
... namely silicone membrane were performed using Franztype diffusion cells that have a receptor phase of ~5 ml, and a diffusional area of 0.788cm2. Sheets of silicone membrane were cut to appropriate sizes in round-shape and soaked overnight in the receptor phase (mixture of PBS and methanol; 1:1 v/v). ...
... namely silicone membrane were performed using Franztype diffusion cells that have a receptor phase of ~5 ml, and a diffusional area of 0.788cm2. Sheets of silicone membrane were cut to appropriate sizes in round-shape and soaked overnight in the receptor phase (mixture of PBS and methanol; 1:1 v/v). ...
validated spectroscopic method for estimation of frovatriptan
... 0.9999). The LOD and LOQ were found to be 0.4362 and 1.3265 g/ ml respectively. The result of estimation of marketed tablet formulation (FROVA) was found to be 99.47% with their % RSD 0.4362.The accuracy of the method was determined by recovery studies. The percentage recovery was found to be 99.83% ...
... 0.9999). The LOD and LOQ were found to be 0.4362 and 1.3265 g/ ml respectively. The result of estimation of marketed tablet formulation (FROVA) was found to be 99.47% with their % RSD 0.4362.The accuracy of the method was determined by recovery studies. The percentage recovery was found to be 99.83% ...
Bad Pharma
.JPG?width=300)
Bad Pharma: How Drug Companies Mislead Doctors and Harm Patients is a book by British physician and academic Ben Goldacre about the pharmaceutical industry, its relationship with the medical profession, and the extent to which it controls academic research into its own products. The book was published in September 2012 in the UK by the Fourth Estate imprint of HarperCollins, and in February 2013 in the United States by Faber and Faber.Goldacre argues in the book that ""the whole edifice of medicine is broken"" because the evidence on which it is based is systematically distorted by the pharmaceutical industry. He writes that the industry finances most of the clinical trials into its own products and much of doctors' continuing education, that clinical trials are often conducted on small groups of unrepresentative subjects and negative data is routinely withheld, and that apparently independent academic papers may be planned and even ghostwritten by pharmaceutical companies or their contractors, without disclosure. Goldacre calls the situation a ""murderous disaster,"" and makes suggestions for action by patients' groups, physicians, academics and the industry itself.Responding to the book's publication, the Association of the British Pharmaceutical Industry issued a statement arguing that the examples the book offers are historical, that the concerns have been addressed, that the industry is among the most regulated in the world, and that it discloses all data in accordance with international standards.In January 2013 Goldacre joined the Cochrane Collaboration, British Medical Journal and others in setting up AllTrials, a campaign calling for the results of all past and current clinical trials to be reported. The British House of Commons Public Accounts Committee expressed concern in January 2014 that drug companies were still only publishing around 50 percent of clinical-trial results.