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A Reference for Health Care Professionals
A Reference for Health Care Professionals

... patients. By one year MG symptoms have completely resolved in about 70% of patients, the titer of AChR antibodies improves, and the electrophysiological abnormalities improve or resolve.20,21 The fact that some patients remain symptomatic long after stopping penicillamine suggests that in some cases ...
EXTEMPORANEOUS PREPARATION OF PAEDIATRIC ORAL
EXTEMPORANEOUS PREPARATION OF PAEDIATRIC ORAL

... lack of suitable dosage forms for use in paediatric patients is a contributor to the widespread need for extemporaneous preparations. Extemporaneous preparations are prepared mainly in hospital and community pharmacies. ...
Formulation Considerations of Inhaled Products
Formulation Considerations of Inhaled Products

... Formulation Considerations of Inhaled Products Inhalation Therapy Nebulizers and Formulations Dry Powder Inhalers and Formulations Metered Dose Inhalers (MDI) and Formulations Conclusions ...
Situation Report National Drug Intelligence Center Synthetic Cathinones (Bath Salts):
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... individuals who seek stimulant effects similar to those produced by cocaine, amphetamine/methamphetamine (illicit and prescription), and MDMA.29 Synthetic cathinones abusers likely are attracted to the drugs because they can evade most drug testing. Most current routine drug testing screens do not d ...
PRODUCT MONOGRAPH PrLINCOCIN® Lincomycin injection USP
PRODUCT MONOGRAPH PrLINCOCIN® Lincomycin injection USP

... One hundred and twelve of the children, ages 6½ to 7½ years, from these patients have been examined and compared with a control group of 65 children born at the same time in the same hospital. LINCOCIN treatment did not result in any drug related abnormalities (physical, dental or developmental) whe ...
Clozapine augmentation
Clozapine augmentation

... augmentation with an antipsychotic. The antipsychotic involved was sulpiride, which is not available in Australia. More research is required to establish the efficacy and safety of the often expensive clozapine augmentation strategies. It is important to note that the addition of another antipsychot ...
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Stability Testing of Pharmaceutical Products
Stability Testing of Pharmaceutical Products

... been established. Stability of the reference material also includes the stability of reagents as well as consistency of the performance of the instrument to be used throughout the period of stability testing. However, system performance and control for drift and discontinuity resulting from changes ...
CALAN - verapamil hydrochloride tablet, film coated G.D. Searle LLC ---------- CALAN®
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Improving Antimicrobial Use - Academy of Managed Care Pharmacy
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Non-pharmacological treatment
Non-pharmacological treatment

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Methadone—metabolism, pharmacokinetics and interactions
Methadone—metabolism, pharmacokinetics and interactions

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Vol. 20, No. 3 Evra Transdermal System
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Macrolids
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(PSD) March 2015 PBAC Meeting
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... For prescribing by nurse practitioners where care of a patient is shared between a nurse practitioner and medical practitioner in a formalised arrangement with an agreed management plan. Further information can be found in the Explanatory Notes for Nurse Practitioners. The risk of drug dependence is ...
Public Assessment Report Scientific discussion Glatirameeracetaat
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... The synthesis of glatiramer acetate results in the complex heterogeneous mixture of random polypeptide chains. In view of the heterogeneity of the substance and the limitations of release controls the MAH has fixed the drug substance manufacturing conditions rigorously in the dossier within narrow r ...
Zeldox capsule, hard ENG SmPC
Zeldox capsule, hard ENG SmPC

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Part 7
Part 7

... about the sequence of CPR first versus shock first, see Part 5: "Electrical Therapies: Automated External Defibrillators, Defibrillation, Cardioversion, and Pacing." If VF/pulseless VT is present (Box 3), providers should deliver 1 shock (Box 4) and then resume CPR immediately, beginning with chest ...
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... harma landscape is changing due to demographic, epidemiological and economic shifts. Growing and aging population, diseases and medical needs has been offering some huge opportunities for Pharma. The markets of the developing world are changing even more radically than those of the developed world. ...
Studies on Variability in Olanzapine Disposition  
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... This thesis comprises of two studies. The aim of study 1 was to investigate factors that may influence the inter- and intra-individual variability of steady-state trough concentrations of OLA and its N-desmethyl metabolite (DMO) in serum. This was done in a cohort of patients treated with oral OLA i ...
Ocular Side Effects of Sildenafil: A Prospective Study
Ocular Side Effects of Sildenafil: A Prospective Study

... hemorrhages.4 However, a recent study found that there is “lack of conclusive evidence to indicate a direct causeeffect relationship between phosphodiesterase enzyme type 5 (PDE5) inhibitor use and vision-threatening ocular events. Men who use PDE5 inhibitors appear to suffer vision-threatening comp ...
neuro 2007 - addiction education home
neuro 2007 - addiction education home

... The endogenous endocannabinoid system encompasses a family of natural signaling lipids ("endocannabinoids") functionally related to Delta9-tetrahydrocannabinol, the psychoactive ingredient of marijuana (cannabis), along with proteins that modulate the endocannabinoids, including enzymes, ...
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Augmentin SR 1000mg Tablets
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Bad Pharma



Bad Pharma: How Drug Companies Mislead Doctors and Harm Patients is a book by British physician and academic Ben Goldacre about the pharmaceutical industry, its relationship with the medical profession, and the extent to which it controls academic research into its own products. The book was published in September 2012 in the UK by the Fourth Estate imprint of HarperCollins, and in February 2013 in the United States by Faber and Faber.Goldacre argues in the book that ""the whole edifice of medicine is broken"" because the evidence on which it is based is systematically distorted by the pharmaceutical industry. He writes that the industry finances most of the clinical trials into its own products and much of doctors' continuing education, that clinical trials are often conducted on small groups of unrepresentative subjects and negative data is routinely withheld, and that apparently independent academic papers may be planned and even ghostwritten by pharmaceutical companies or their contractors, without disclosure. Goldacre calls the situation a ""murderous disaster,"" and makes suggestions for action by patients' groups, physicians, academics and the industry itself.Responding to the book's publication, the Association of the British Pharmaceutical Industry issued a statement arguing that the examples the book offers are historical, that the concerns have been addressed, that the industry is among the most regulated in the world, and that it discloses all data in accordance with international standards.In January 2013 Goldacre joined the Cochrane Collaboration, British Medical Journal and others in setting up AllTrials, a campaign calling for the results of all past and current clinical trials to be reported. The British House of Commons Public Accounts Committee expressed concern in January 2014 that drug companies were still only publishing around 50 percent of clinical-trial results.
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